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[194258_x_at]

Description CEK069A8R_rc /REP_DB=TREMBL Accession /GB=D65821 /CHR=1 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk69a8 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 61      6grp_high1_10_10 > 18      4grp_highest_8_8 > 57      4grp_high_8_8 > 34      6grp_highest_nonorm > 40      6grp_total > 06      4grp_total > 46      6grp_highest_sub > De      6grp_cgc > 03      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 600
1 2 3 4 range
A 960.6
(3)
P 		542.4
(-1.2)
P 		433.1
(-2.3)
P 		360.2
(-3)
P 		600
B 655.9
(3)
P 		590.3
(1.2)
P 		434.1
(-3)
P 		503.8
(-1.1)
P 		222
C 803.6
(3)
P 		593.3
(-1.1)
P 		506.8
(-2.8)
P 		496.1
(-3)
P 		308
avr 806.7
(3) 		575.3
(-0.9) 		458
(-2.9) 		453.4
(-3) 		353

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 658
1 2 3 4 5 6 range
A 959.6
(3)
P 		667.2
(-0.2)
P 		602.1
(-0.9)
P 		405.1
(-3)
P 		685
(0)
P 		471
(-2.3)
P 		555
B 1062.9
(3)
P 		827.8
(0.6)
P 		477.4
(-3)
P 		610
(-1.6)
P 		621.2
(-1.5)
P 		626.3
(-1.5)
P 		586
C 880
(2.8)
P 		894.3
(3)
P 		484.6
(-2.9)
P 		586.2
(-1.4)
P 		551.8
(-1.9)
P 		478.6
(-3)
P 		416
avr 967.5
(3) 		796.4
(0.7) 		521.4
(-3) 		533.8
(-2.8) 		619.3
(-1.7) 		525.3
(-2.9) 		446
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 297
1 2 3 4 range
A 349.8
(3)
P 		117.7
(-1.7)
P 		113.2
(-1.8)
P 		52.7
(-3)
P 		297
B 209.2
(3)
P 		145.8
(-0.5)
P 		100.6
(-3)
P 		107.4
(-2.6)
P 		109
C 266
(3)
P 		170.6
(-0.1)
P 		176.6
(0.1)
P 		83.7
(-3)
P 		182
avr 275
(3) 		144.7
(-1) 		130.1
(-1.5) 		81.3
(-3) 		194

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 267
1 2 3 4 5 6 range
A 176.9
(0.3)
P 		237.3
(3)
P 		131.1
(-1.7)
P 		102.7
(-3)
P 		206.7
(1.6)
P 		114.7
(-2.5)
P 		135
B 369.9
(3)
P 		275.5
(0.8)
P 		115.9
(-3)
P 		161.6
(-1.9)
P 		252.4
(0.2)
P 		233.5
(-0.2)
P 		254
C 326.2
(3)
P 		272.9
(1.5)
P 		123.3
(-2.8)
P 		117.9
(-3)
P 		178.5
(-1.3)
P 		160.2
(-1.8)
P 		208
avr 291
(3) 		261.9
(2) 		123.4
(-3) 		127.4
(-2.9) 		212.5
(0.2) 		169.5
(-1.3) 		168
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 194258_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.20433
Sequence Type Exemplar sequence
Representative Public ID CEK069A8R NCBI
Target Description CEK069A8R_rc /REP_DB=TREMBL Accession /GB=D65821 /CHR=1 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk69a8 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001025812(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001025812 NCBI Caenorhabditis elegans TOLl (Drosophila) family member (tol-1) (tol-1) mRNA, complete cds. 11/11 None
C07F11.1 ENSEMBL cdna:known chromosome:CEL140:I:444002:461590:1 gene:C07F11.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:461233-461572(+) 93.81 100.0
Public Domain and Genome References
Gene Title
Gene Symbol tol-1
Ensembl C07F11.1
Entrez Gene 171635 Entrez gene
SwissProt Q9N5Z3 EMBL-EBI
WormBase CE28818 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1624790_AT Toll-6 dm
DROSGENOME1:153641_AT Toll-6 dm
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
5623 cell inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4888 transmembrane receptor activity inferred from electronic annotation QuickGO AmiGO
5057 receptor signaling protein activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAF39752 Toll (drosophila) family protein 1 [Caenorhabditis elegans] ref|NP_001020983.1| TOLl (Drosophila) family member (tol-1) [Caenorhabditis elegans] 0.0
blast AAK37544 Toll-like receptor TOL-1 [Caenorhabditis elegans] 0.0
blast CAE74340 Hypothetical protein CBG22058 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.48
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.13
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.023
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.0038
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.07
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.045
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.49
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.0063
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.012
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.034
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.95
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.022
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.034
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.39
Pfam IPR001611 EMBL-EBI Leucine-rich repeat 0.02
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_001020983.1 1 999-1021
C07F11.1 1 999-1021
Sequence
Target Sequence 
>C. ELEGANS:194258_X_AT
tcctcttccaaatgtacgagtttccattattcacgaggtttctttttcacccccaattct
tctgtgcacaatttgccattttttgaatttttacaacaataccggtactatatttttcga
ttttctttctttttctatgaatcttgccatcattctctaataattgaccagcgattatat
ttttgatttaataattgaatattctcgtttttcagttcaaattattgcttttttctgtca
ccacaaattcaaattctcgtcctaccctgtgtgatcttctgtaat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCCTCTTCCAAATGTACGAGTTTCC 297 583 36 Antisense
TGTACGAGTTTCCATTATTCACGAG 648 559 48 Antisense
CATTATTCACGAGGTTTCTTTTTCA 675 213 60 Antisense
AATTCTTCTGTGCACAATTTGCCAT 320 177 90 Antisense
TTTCGATTTTCTTTCTTTTTCTATG 408 671 150 Antisense
TCTTTTTCTATGAATCTTGCCATCA 47 617 163 Antisense
AATCTTGCCATCATTCTCTAATAAT 348 169 175 Antisense
AATATTCTCGTTTTTCAGTTCAAAT 29 175 233 Antisense
AATTATTGCTTTTTTCTGTCACCAC 446 175 255 Antisense
CACAAATTCAAATTCTCGTCCTACC 313 193 277 Antisense
CCTACCCTGTGTGATCTTCTGTAAT 148 269 296 Antisense
Sequence Source Affymetrix Proprietary Database