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[194246_x_at]

Description g2264333 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=F11A6.1B /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=F11A6.1B /WP=CE17654 /CHR=1 /FEA=Genomic Cluster /GEN=kpc-1 /DEF=celfurPC protein; Subtilase family of serine proteases
Cluster 6grp_highest_10_10 > 94      6grp_high1_10_10 > 58      4grp_highest_8_8 > 23      4grp_high_8_8 > 13      6grp_highest_nonorm > 85      6grp_total > 48      4grp_total > 03      6grp_highest_sub > Cu      6grp_cgc > 28      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2308
1 2 3 4 range
A 1082.8
(-2.5)
P 		1195.2
(-2.2)
P 		922.9
(-3)
P 		2991.6
(3)
P 		2069
B 1230.3
(-2.1)
P 		956.8
(-2.8)
P 		889.9
(-3)
P 		3198.2
(3)
P 		2308
C 1006.1
(-2.7)
P 		931.2
(-2.9)
P 		896.5
(-3)
P 		2817.5
(3)
P 		1921
avr 1106.4
(-2.4) 		1027.7
(-2.6) 		903.1
(-3) 		3002.4
(3) 		2099

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 588
1 2 3 4 5 6 range
A 1045.8
(2.3)
P 		805.4
(-0.2)
P 		529.2
(-3)
P 		668.8
(-1.6)
P 		700
(-1.3)
P 		1117.2
(3)
P 		588
B 792.6
(-0.4)
P 		855.5
(0.4)
P 		581
(-3)
P 		742.4
(-1)
P 		764.9
(-0.7)
P 		1065.4
(3)
P 		484
C 788.7
(-0.2)
P 		734.8
(-0.9)
P 		585.4
(-3)
P 		667.8
(-1.8)
P 		633.1
(-2.3)
P 		1013.8
(3)
P 		428
avr 875.7
(0.7) 		798.6
(-0.2) 		565.2
(-3) 		693
(-1.5) 		699.3
(-1.4) 		1065.5
(3) 		500
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 475
1 2 3 4 range
A 394.2
(1.7)
P 		259.4
(-2.4)
P 		241.3
(-3)
P 		437.9
(3)
P 		197
B 392.3
(-0.7)
P 		236.3
(-2.6)
P 		206.2
(-3)
P 		681.5
(3)
P 		475
C 333.1
(-1.1)
P 		267.7
(-3)
P 		312.5
(-1.7)
P 		475.1
(3)
P 		207
avr 373.2
(-0.4) 		254.5
(-3) 		253.3
(-3) 		531.5
(3) 		278

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 282
1 2 3 4 5 6 range
A 192.8
(-0.3)
P 		286.4
(3)
P 		115.3
(-3)
P 		169.6
(-1.1)
P 		211.2
(0.4)
P 		272
(2.5)
P 		171
B 275.8
(0.2)
P 		284.8
(0.4)
P 		141.1
(-3)
P 		196.6
(-1.7)
P 		310.8
(1)
P 		397.3
(3)
P 		256
C 292.3
(1.6)
P 		224.2
(-0.4)
P 		149
(-2.6)
P 		134.3
(-3)
P 		204.9
(-0.9)
P 		339.4
(3)
P 		205
avr 253.6
(0.5) 		265.1
(0.9) 		135.1
(-3) 		166.8
(-2.1) 		242.3
(0.2) 		336.2
(3) 		201
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 194246_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.23080
Sequence Type Exemplar sequence
Representative Public ID 2264333 NCBI
Target Description g2264333 /REP_DB=GenBank Identifier /5_PRIME_EXT_ID=F11A6.1B /5_PRIME_EXT_DB=WormBase Gene ID /WB_GENE_ID=F11A6.1B /WP=CE17654 /CHR=1 /FEA=Genomic Cluster /GEN=kpc-1 /DEF=celfurPC protein; Subtilase family of serine proteases
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060573(10), NM_001025929(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060573 NCBI Caenorhabditis elegans Kex-2 Proprotein Convertase family member (kpc-1) (kpc-1) mRNA, complete cds. 10/11 A 
NM_001025929 NCBI Caenorhabditis elegans Kex-2 Proprotein Convertase family member (kpc-1) (kpc-1) mRNA, complete cds. 11/11 None
SNAP00000041218 ENSEMBL cdna:SNAP chromosome:CEL140:I:11684167:11688754:1 10/11 None
GENEFINDER00000041221 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:11688016:11688754:1 10/11 None
F11A6.1a ENSEMBL cdna:known chromosome:CEL140:I:11684065:11688874:1 gene:F11A6.1 10/11 A 
F11A6.1b ENSEMBL cdna:known chromosome:CEL140:I:11684066:11689089:1 gene:F11A6.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:11684098-11688686(+) 90.98 100.0
Public Domain and Genome References
Ensembl F11A6.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB04086 Hypothetical protein F11A6.1a [Caenorhabditis elegans] ref|NP_492974.2| Kex-2 Proprotein Convertase family member (kpc-1) [Caenorhabditis elegans] 0.0
blast AAB63525 celfur protein 0.0
blast CAB04085 Hypothetical protein F11A6.1b [Caenorhabditis elegans] ref|NP_001021101.1| Kex-2 Proprotein Convertase family member (kpc-1) [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 6.3E-74
Pfam IPR000209 EMBL-EBI Peptidase S8 and S53, subtilisin, kexin, sedolisin 1.0E-126
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 1.7E-65
Pfam IPR002884 EMBL-EBI Peptidase S8B, proprotein convertase, P domain 1.7E-65
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000041221 1 159-176
Sequence
Target Sequence 
>C. ELEGANS:194246_X_AT
gaaatttccagggacttctacgcgttttcagaagtttccgaaaattctagaaattgagaa
aatgtttagaaattccaaaaaactccaagtttttagaaatatccccaacggaaaccgcct
tcaactccaactttactccgacggatgttatggtggagccgatgagaataaggtgtctta
tgtggagcacgtgcaggcaatcgtcacattgaaagctccaaaacgtggagatttgcaaat
ctacttgacttctccgtcaggcacaaaatccacgttgctcacaaaaagagcacgcgacac
atcacgaagtggcttcacagattgggctttcatgacgacccataactggggggagcaggc
cgccgggctgtggattctggaaatcgataatgatggatgggatggcgccgagcttgtaaa
atgggaactcgtgctctacggaactgatcgggaaaccggcgactttggaggccaacatgc
ttcaccgttagccgtcagaagtgtccagatggaagccacgtcatccggcacccaatattc
aattttccacgtcatcact

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAATTTCCAGGGACTTCTACGCGT 514 361 1700 Antisense
CTCCAACTTTACTCCGACGGATGTT 413 235 1824 Antisense
TGGAGCACGTGCAGGCAATCGTCAC 247 549 1882 Antisense
TGCAAATCTACTTGACTTCTCCGTC 305 577 1933 Antisense
GACTTCTCCGTCAGGCACAAAATCC 639 369 1946 Antisense
GCACGCGACACATCACGAAGTGGCT 47 315 1989 Antisense
GTGGCTTCACAGATTGGGCTTTCAT 445 491 2008 Antisense
GAACTCGTGCTCTACGGAACTGATC 339 347 2124 Antisense
CCGTTAGCCGTCAGAAGTGTCCAGA 274 261 2184 Antisense
CCAGATGGAAGCCACGTCATCCGGC 205 271 2204 Antisense
ATATTCAATTTTCCACGTCATCACT 199 19 2234 Antisense
Sequence Source GenBank