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[194228_x_at]

Description AV203628 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=T22H2.6A /5_PRIME_EXT_DB=WormBase Gene ID /GB=AV203628 /WB_GENE_ID=T22H2.6A /WP=CE24004 /CHR=1 /FEA=Genomic Cluster /DEF=granulin precursor; Caenorhabditis elegans cDNA clone:yk579a12 : 5prime end, single read.
Cluster 6grp_highest_10_10 > 27      6grp_high1_10_10 > 72      4grp_highest_8_8 > 30      4grp_high_8_8 > 04      6grp_highest_nonorm > 55      6grp_total > 73      4grp_total > 04      6grp_highest_sub > 03_04      6grp_high1_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1072
1 2 3 4 range
A 1539.1
(-2.2)
P 		1410.5
(-3)
P 		1463.3
(-2.7)
P 		2424.8
(3)
P 		1014
B 1727.8
(-0.9)
P 		1396
(-3)
P 		1585.4
(-1.8)
P 		2364.1
(3)
P 		968
C 1600.3
(-1.1)
P 		1352.5
(-3)
P 		1367.4
(-2.9)
P 		2128.6
(3)
P 		776
avr 1622.4
(-1.5) 		1386.3
(-3) 		1472
(-2.4) 		2305.8
(3) 		920

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 774
1 2 3 4 5 6 range
A 1399.9
(-3)
P 		1481.1
(-2.2)
P 		2043.1
(3)
P 		1980.1
(2.4)
P 		1830.1
(1)
P 		1553.4
(-1.6)
P 		643
B 1327.2
(-3)
P 		1498.5
(-1.7)
P 		2032.2
(2.5)
P 		2100.8
(3)
P 		1916.4
(1.6)
P 		1421.7
(-2.3)
P 		774
C 1407.8
(-3)
P 		1496.4
(-2.1)
P 		1980.8
(3)
P 		1851.4
(1.6)
P 		1725.3
(0.3)
P 		1610.4
(-0.9)
P 		573
avr 1378.3
(-3) 		1492
(-1.9) 		2018.7
(3) 		1977.4
(2.6) 		1823.9
(1.2) 		1528.5
(-1.6) 		640
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 254
1 2 3 4 range
A 560.4
(3)
P 		306.2
(-3)
P 		382.5
(-1.2)
P 		354.9
(-1.9)
P 		254
B 551
(3)
P 		344.8
(-3)
P 		367.4
(-2.3)
P 		503.8
(1.6)
P 		206
C 529.7
(3)
P 		388.8
(-1.9)
P 		476.6
(1.1)
P 		358.9
(-3)
P 		171
avr 547
(3) 		346.6
(-3) 		408.8
(-1.1) 		405.9
(-1.2) 		200

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 521
1 2 3 4 5 6 range
A 258.1
(-3)
P 		526.7
(2.5)
P 		444.9
(0.8)
P 		502.2
(2)
P 		552.2
(3)
P 		378.2
(-0.5)
P 		294
B 461.8
(-3)
P 		498.8
(-2.3)
P 		493.5
(-2.4)
P 		556.4
(-1.2)
P 		778.6
(3)
P 		530.1
(-1.7)
P 		317
C 521.8
(1.8)
P 		456.6
(-0.3)
P 		504.2
(1.3)
P 		372.3
(-3)
P 		558.3
(3)
P 		539.1
(2.4)
P 		186
avr 413.9
(-3) 		494
(-0.8) 		480.9
(-1.1) 		477
(-1.2) 		629.7
(3) 		482.5
(-1.1) 		216
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 194228_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.22696
Sequence Type Exemplar sequence
Representative Public ID AV203628 NCBI
Target Description AV203628 /REP_DB=TREMBL Accession /5_PRIME_EXT_ID=T22H2.6A /5_PRIME_EXT_DB=WormBase Gene ID /GB=AV203628 /WB_GENE_ID=T22H2.6A /WP=CE24004 /CHR=1 /FEA=Genomic Cluster /DEF=granulin precursor; Caenorhabditis elegans cDNA clone:yk579a12 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060580(10), NM_060581(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060580 NCBI Caenorhabditis elegans T22H2.6a (T22H2.6) mRNA, complete cds. 10/11 A 
NM_060581 NCBI Caenorhabditis elegans T22H2.6b (T22H2.6) mRNA, complete cds. 9/11 A 
GENEFINDER00000038049 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:11707291:11711715:1 10/11 None
SNAP00000038045 ENSEMBL cdna:SNAP chromosome:CEL140:I:11709987:11711715:1 10/11 None
T22H2.6a ENSEMBL cdna:known chromosome:CEL140:I:11709753:11711804:1 gene:T22H2.6 10/11 A 
T22H2.6b ENSEMBL cdna:known chromosome:CEL140:I:11709753:11711741:1 gene:T22H2.6 9/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000018817 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:11709684-11711647(+) 100.0 100.0
Public Domain and Genome References
Ensembl T22H2.6
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB54304 Hypothetical protein T22H2.6a [Caenorhabditis elegans] ref|NP_492981.1| T22H2.6a [Caenorhabditis elegans] 0.0
blast E87929 protein T22H2.6 [imported] - Caenorhabditis elegans 0.0
blast CAB54305 Hypothetical protein T22H2.6b [Caenorhabditis elegans] ref|NP_492982.1| T22H2.6b [Caenorhabditis elegans] 0.0
blast CAB54305 Hypothetical protein T22H2.6b [Caenorhabditis elegans] ref|NP_492982.1| T22H2.6b [Caenorhabditis elegans] 1.0E-172
blast CAB54304 Hypothetical protein T22H2.6a [Caenorhabditis elegans] ref|NP_492981.1| T22H2.6a [Caenorhabditis elegans] 1.0E-172
Protein Domains
Database ID Description E-Value
Pfam IPR000118 EMBL-EBI Granulin 1.5E-22
Pfam IPR000118 EMBL-EBI Granulin 3.9E-20
Pfam IPR000118 EMBL-EBI Granulin 3.7E-7
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 1.1E-26
Pfam IPR003003 EMBL-EBI 7TM chemoreceptor, subfamily 2 3.1E-31
Pfam IPR000118 EMBL-EBI Granulin 1.5E-22
Pfam IPR000118 EMBL-EBI Granulin 3.9E-20
Pfam IPR000118 EMBL-EBI Granulin 3.7E-7
Pfam IPR000118 EMBL-EBI Granulin 1.5E-22
Pfam IPR000118 EMBL-EBI Granulin 3.9E-20
Pfam IPR000118 EMBL-EBI Granulin 3.7E-7
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_492981.1 2 21-40,69-91
NP_492982.1 2 21-40,69-91
T22H2.6a 2 21-40,69-91
T22H2.6b 2 21-40,69-91
GENEFINDER00000038049 4 15-37,116-135,174-196,217-239
Sequence
Target Sequence 
>C. ELEGANS:194228_X_AT
tcgtctgcccggacaaggctagcaagtgcccagatggttcgacgtgctgtctgttggagc
agggaagctacggatgttgcccggtgccgaatgcggtgtgctgcgcagatatgttgcact
gctgtccgaatggatttacgtgtcacgggcagttttgctcgcagaatgtcgccatgatcc
cacacctgcggaagttcgcctccacctccatccatcgcaagccagcagtggagttccttt
ccgaagaagaggaggatgatgatgatgaggaatccacgtcatcagaggatccagaaagcg
atgtggacccgattgcctgtggagttggaaagacgtgtccagcaaaaaccacgtgctgta
atgtccgaggaaagaatggggagccgaagacgatgtgttgtccattgagcaacgccatct
gctgtgagaacacttgctgcccag

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCGTCTGCCCGGACAAGGCTAGCAA 45 599 541 Antisense
AAGTGCCCAGATGGTTCGACGTGCT 97 159 564 Antisense
GGGAAGCTACGGATGTTGCCCGGTG 225 493 602 Antisense
GATATGTTGCACTGCTGTCCGAATG 595 425 648 Antisense
TTACGTGTCACGGGCAGTTTTGCTC 418 681 676 Antisense
TTTTGCTCGCAGAATGTCGCCATGA 555 677 693 Antisense
GCAAGCCAGCAGTGGAGTTCCTTTC 164 321 757 Antisense
GAAAGCGATGTGGACCCGATTGCCT 538 359 834 Antisense
AACCACGTGCTGTAATGTCCGAGGA 553 147 887 Antisense
TTGTCCATTGAGCAACGCCATCTGC 614 701 938 Antisense
TGCTGTGAGAACACTTGCTGCCCAG 308 581 960 Antisense
Sequence Source Affymetrix Proprietary Database