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[194187_x_at] Kunitz/Bovine pancreatic trypsin inhibitor domain (10 domains), Thyroglobulin type-1 repeat

Description C62304 /REP_DB=TREMBL Accession /GB=C62304 /CHR=5 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk250a7 : 5prime end, single read.
Cluster 6grp_highest_10_10 > 10      6grp_high1_10_10 > 14      4grp_highest_8_8 > 02      4grp_high_8_8 > 46      6grp_highest_nonorm > 22      6grp_total > 03      4grp_total > 49      6grp_cgc > 51      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2584
1 2 3 4 range
A 46.9
(-3)
P 		2245.8
(2.6)
P 		2406.4
(3)
P 		115.7
(-2.8)
P 		2360
B 47.7
(-3)
P 		2568
(3)
P 		2490.4
(2.8)
P 		105.8
(-2.9)
P 		2520
C 47
(-3)
P 		2631.1
(3)
P 		2529.5
(2.8)
P 		123
(-2.8)
P 		2584
avr 47.2
(-3) 		2481.6
(3) 		2475.4
(3) 		114.8
(-2.8) 		2434

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2115
1 2 3 4 5 6 range
A 1669.5
(2.7)
P 		1689.3
(2.8)
P 		1469.8
(1.8)
P 		1205.1
(0.5)
P 		1729.3
(3)
P 		477.4
(-3)
P 		1252
B 2536.4
(3)
P 		2083.4
(1.5)
P 		1345.3
(-0.8)
P 		2026.1
(1.4)
P 		1200
(-1.3)
P 		664.1
(-3)
P 		1872
C 2096
(3)
P 		2042.9
(2.8)
P 		1065.1
(-0.7)
P 		1483.5
(0.8)
P 		1570.2
(1.1)
P 		421.9
(-3)
P 		1674
avr 2100.6
(3) 		1938.5
(2.4) 		1293.4
(-0.1) 		1571.6
(1) 		1499.8
(0.7) 		521.1
(-3) 		1580
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 866
1 2 3 4 range
A 17.1
(-3)
P 		487.5
(1.6)
P 		629.1
(3)
P 		16.9
(-3)
P 		612
B 15.2
(-3)
P 		634.2
(3)
P 		577.1
(2.4)
P 		22.5
(-2.9)
P 		619
C 15.5
(-3)
P 		756.4
(2.1)
P 		881.6
(3)
P 		20.7
(-3)
P 		866
avr 15.9
(-3) 		626
(2.4) 		695.9
(3) 		20
(-3) 		680

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 766
1 2 3 4 5 6 range
A 307.8
(-0.6)
P 		600.8
(3)
P 		320.1
(-0.5)
P 		305.6
(-0.7)
P 		521.8
(2)
P 		116.2
(-3)
P 		485
B 882.5
(3)
P 		693.5
(1.2)
P 		326.7
(-2.3)
P 		536.6
(-0.3)
P 		487.5
(-0.7)
P 		247.6
(-3)
P 		635
C 776.9
(3)
P 		623.3
(1.6)
P 		271.1
(-1.8)
P 		298.3
(-1.5)
P 		508.1
(0.5)
P 		141.2
(-3)
P 		636
avr 655.7
(3) 		639.2
(2.8) 		306
(-1.3) 		380.2
(-0.4) 		505.8
(1.2) 		168.3
(-3) 		487
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 194187_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.21835
Sequence Type Exemplar sequence
Representative Public ID C62304 NCBI
Target Description C62304 /REP_DB=TREMBL Accession /GB=C62304 /CHR=5 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk250a7 : 5prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Genome Target Overlap based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade B annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075592
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
GENEFINDER00000024491 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:20665285:20679891:1 None
W01F3.3 ENSEMBL cdna:known chromosome:CEL140:V:20663308:20676528:1 gene:W01F3.3 A 
NM_075592 NCBI Caenorhabditis elegans W01F3.3 (W01F3.3) mRNA, complete cds. A 
SNAP00000024490 ENSEMBL cdna:SNAP chromosome:CEL140:V:20665285:20676211:1 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:20676147-20676529(+) 88.48 100.0
Public Domain and Genome References
Gene Title Kunitz/Bovine pancreatic trypsin inhibitor domain (10 domains), Thyroglobulin type-1 repeat
Gene Symbol mlt-11
Ensembl W01F3.3
Entrez Gene 180352 Entrez gene
SwissProt O45881 EMBL-EBI
WormBase CE16531 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB07294 Hypothetical protein W01F3.3 [Caenorhabditis elegans] ref|NP_507993.1| W01F3.3 [Caenorhabditis elegans] 0.0
blast CAE61690 Hypothetical protein CBG05636 [Caenorhabditis briggsae] 0.0
blast AAN10061 Kunitz-like protease inhibitor precursor [Ancylostoma caninum] 2.0E-67
Protein Domains
Database ID Description E-Value
Pfam IPR000716 EMBL-EBI Thyroglobulin type-1 3.0E-18
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.6E-23
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.6E-27
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 6.1E-28
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 7.0E-25
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.0E-26
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 4.9E-28
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.0E-26
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 3.4E-21
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 9.8E-30
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.3E-16
Pfam IPR000716 EMBL-EBI Thyroglobulin type-1 3.0E-18
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.6E-23
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.6E-27
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 6.1E-28
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 7.0E-25
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.0E-26
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 4.9E-28
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 2.0E-26
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 3.4E-21
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 9.8E-30
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.3E-16
Trans Membrane
ID Number Of Domains Domain Boundaries
GENEFINDER00000024491 3 3197-3219,3232-3254,3269-3291
Sequence
Target Sequence 
>C. ELEGANS:194187_X_AT
aaagtccgactgtgaagctctgtgcctgtaattgttttttcttttttttttcgtttttct
tattgacgtccttcttctaagattttctcattcttcccacaccgaaatctcagtttttcc
tctttttttaattttgcagaactcttttttttgagttttccttgactgattgatatttct
tccaaagttgccaagccttaatttttacgttgtacgttttttttcacaaatccacaaaat
tctatatttattttctctgtaactttgctcctgggctcagccatccctaataatat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAGTCCGACTGTGAAGCTCTGTGC 588 121 46 Antisense
GCTCTGTGCCTGTAATTGTTTTTTC 465 299 62 Antisense
TCGTTTTTCTTATTGACGTCCTTCT 494 603 96 Antisense
GACGTCCTTCTTCTAAGATTTTCTC 361 375 110 Antisense
CTAAGATTTTCTCATTCTTCCCACA 681 225 122 Antisense
CACACCGAAATCTCAGTTTTTCCTC 283 191 143 Antisense
TAATTTTGCAGAACTCTTTTTTTTG 342 635 174 Antisense
CCTTGACTGATTGATATTTCTTCCA 562 269 205 Antisense
ATTTCTTCCAAAGTTGCCAAGCCTT 109 17 220 Antisense
TTATTTTCTCTGTAACTTTGCTCCT 175 679 293 Antisense
TGGGCTCAGCCATCCCTAATAATAT 185 553 317 Antisense
Sequence Source Affymetrix Proprietary Database