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[194184_x_at] serine/threonine kinase

Description CEK037G6R_rc /REP_DB=TREMBL Accession /GB=D33894 /CHR=4 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk37g6 : 3prime end, single read.
Cluster 6grp_highest_10_10 > 94      6grp_high1_10_10 > 59      4grp_highest_8_8 > 38      4grp_high_8_8 > 03      6grp_highest_nonorm > 84      6grp_total > 49      4grp_total > 05      6grp_highest_sub > Cu      6grp_cgc > 19      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 493
1 2 3 4 range
A 420.2
(-0.2)
P 		333.9
(-1.9)
P 		280
(-3)
P 		581.4
(3)
P 		301
B 598.7
(0.9)
P 		336.3
(-2.4)
P 		284.4
(-3)
P 		772.6
(3)
P 		488
C 492.3
(-0.7)
P 		378.3
(-3)
P 		416.1
(-2.2)
P 		672.1
(3)
P 		294
avr 503.7
(0) 		349.5
(-2.6) 		326.8
(-3) 		675.4
(3) 		349

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 570
1 2 3 4 5 6 range
A 614.1
(1.7)
P 		525.2
(0.5)
P 		281.2
(-3)
P 		405.5
(-1.2)
P 		647.3
(2.2)
P 		703.1
(3)
P 		422
B 524.3
(-0.1)
P 		606
(0.7)
P 		253.4
(-3)
P 		507.4
(-0.3)
P 		589
(0.5)
P 		822.9
(3)
P 		570
C 636.9
(3)
P 		490
(-0.7)
P 		439.3
(-1.9)
P 		395.7
(-3)
P 		596
(2)
P 		615.4
(2.5)
P 		241
avr 591.8
(1.1) 		540.4
(0.3) 		324.6
(-3) 		436.2
(-1.3) 		610.8
(1.4) 		713.8
(3) 		389
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 125
1 2 3 4 range
A 153
(3)
P 		72.5
(-3)
P 		73.2
(-2.9)
P 		85.1
(-2.1)
P 		81
B 190.9
(3)
P 		83.1
(-2.2)
P 		65.9
(-3)
P 		164.6
(1.7)
P 		125
C 163
(3)
P 		108.8
(-3)
P 		145
(1)
P 		113.3
(-2.5)
P 		54
avr 169
(3) 		88.1
(-3) 		94.7
(-2.5) 		121
(-0.6) 		81

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 246
1 2 3 4 5 6 range
A 113.2
(-0.7)
P 		186.8
(2.6)
P 		61.2
(-3)
P 		102.8
(-1.1)
P 		195.3
(3)
P 		171.2
(1.9)
P 		134
B 182.4
(-0)
P 		201.7
(0.4)
P 		61.5
(-3)
P 		134.4
(-1.2)
P 		239.3
(1.3)
P 		306.9
(3)
P 		245
C 236.1
(3)
P 		149.5
(-0.3)
P 		111.8
(-1.8)
P 		79.6
(-3)
P 		192.8
(1.3)
P 		206
(1.8)
P 		157
avr 177.2
(1) 		179.3
(1) 		78.2
(-3) 		105.6
(-1.9) 		209.1
(2.2) 		228
(3) 		150
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 194184_x_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.21477
Sequence Type Exemplar sequence
Representative Public ID CEK037G6R NCBI
Target Description CEK037G6R_rc /REP_DB=TREMBL Accession /GB=D33894 /CHR=4 /FEA=Genomic Cluster /DEF=C.elegans cDNA clone yk37g6 : 3prime end, single read.
Cluster Evidence This cluster is supported by a Genomic Cluster.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069760(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069760 NCBI Caenorhabditis elegans protein KINase family member (kin-4) (kin-4) mRNA, complete cds. 11/11 None
C10C6.1 ENSEMBL cdna:known chromosome:CEL140:IV:11439402:11447021:1 gene:C10C6.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11446683-11446998(+) 100.0 100.0
Public Domain and Genome References
Gene Title serine/threonine kinase
Gene Symbol kin-4
Ensembl C10C6.1
Entrez Gene 178068 Entrez gene
SwissProt P90744 EMBL-EBI
WormBase CE20493 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.7547.1.S1_AT similar to Microtubule-associated serine/threonine-protein kinase 2 cfa
CANINE_2:CFAAFFX.7549.1.S1_S_AT similar to Microtubule-associated serine/threonine-protein kinase 2 cfa
CANINE_2:CFAAFFX.7571.1.S1_S_AT similar to Microtubule-associated serine/threonine-protein kinase 2 cfa
CANINE_2:CFAAFFX.7583.1.S1_S_AT similar to Microtubule-associated serine/threonine-protein kinase 2 cfa
DROSOPHILA_2:1630573_AT dm
DROSGENOME1:151608_S_AT dm
DROSGENOME1:142528_AT dm
CHICKEN:GGA.9937.1.S1_AT similar to Mast2 protein gga
CHICKEN:GGAAFFX.6491.1.S1_AT similar to Mast2 protein gga
CHICKEN:GGAAFFX.6507.1.S1_AT similar to Mast2 protein gga
CHICKEN:GGAAFFX.6507.2.S1_S_AT similar to Mast2 protein gga
CHICKEN:GGAAFFX.6507.4.S1_S_AT similar to Mast2 protein gga
CHICKEN:GGAAFFX.6507.5.S1_S_AT similar to Mast2 protein gga
HG-U133_PLUS_2:215903_S_AT microtubule associated serine/threonine kinase 2 hs
HG-U133A_2:215903_S_AT microtubule associated serine/threonine kinase 2 hs
HG-U133A:215903_S_AT microtubule associated serine/threonine kinase 2 hs
HG-U133_PLUS_2:215661_AT microtubule associated serine/threonine kinase 2 hs
HG-U133A_2:215661_AT microtubule associated serine/threonine kinase 2 hs
HG-U133A:215661_AT microtubule associated serine/threonine kinase 2 hs
HG-U133_PLUS_2:211593_S_AT microtubule associated serine/threonine kinase 2 hs
HG-U133A:211593_S_AT microtubule associated serine/threonine kinase 2 hs
HG-U133A_2:211593_S_AT microtubule associated serine/threonine kinase 2 hs
HG-U133_PLUS_2:215660_S_AT microtubule associated serine/threonine kinase 2 hs
HG-U133A_2:215660_S_AT microtubule associated serine/threonine kinase 2 hs
HG-U133A:215660_S_AT microtubule associated serine/threonine kinase 2 hs
HU35KSUBB:RC_R53574_AT microtubule associated serine/threonine kinase 2 hs
U133_X3P:G13537203_3P_S_AT microtubule associated serine/threonine kinase 2 hs
U133_X3P:HS.306804.0.A1_3P_S_AT microtubule associated serine/threonine kinase 2 hs
U133_X3P:HS.306804.0.A1_3P_AT microtubule associated serine/threonine kinase 2 hs
U133_X3P:HS.101474.1.S1_3P_AT microtubule associated serine/threonine kinase 2 hs
U133_X3P:215660_3P_S_AT microtubule associated serine/threonine kinase 2 hs
HG-U95AV2:41114_AT microtubule associated serine/threonine kinase 2 hs
HG-U133_PLUS_2:215662_AT Microtubule associated serine/threonine kinase 2 hs
HG-U133A_2:215662_AT Microtubule associated serine/threonine kinase 2 hs
HG-U133A:215662_AT Microtubule associated serine/threonine kinase 2 hs
U133_X3P:HS.306804.0.S1_3P_AT Microtubule associated serine/threonine kinase 2 hs
HG-U95B:59575_AT Microtubule associated serine/threonine kinase 2 hs
HU35KSUBC:RC_N25619_AT Microtubule associated serine/threonine kinase 2 hs
HU35KSUBD:RC_D20269_AT Microtubule associated serine/threonine kinase 2 hs
MU11KSUBB:MSA.240.0_S_AT microtubule associated serine/threonine kinase 2 mm
MG-U74CV2:134878_AT microtubule associated serine/threonine kinase 2 mm
MG-U74AV2:160938_AT microtubule associated serine/threonine kinase 2 mm
MOE430A:1417324_AT microtubule associated serine/threonine kinase 2 mm
MOUSE430A_2:1417324_AT microtubule associated serine/threonine kinase 2 mm
MOUSE430_2:1417324_AT microtubule associated serine/threonine kinase 2 mm
MOE430B:1456927_AT microtubule associated serine/threonine kinase 2 mm
MOUSE430_2:1456927_AT microtubule associated serine/threonine kinase 2 mm
MOE430B:1444813_AT Microtubule associated serine/threonine kinase 2 (Mast2), mRNA mm
MOUSE430_2:1444813_AT Microtubule associated serine/threonine kinase 2 (Mast2), mRNA mm
MG-U74CV2:129245_AT Microtubule associated serine/threonine kinase 2 (Mast2), mRNA mm
MOE430B:1440321_AT Microtubule associated serine/threonine kinase 2 (Mast2), mRNA mm
MOUSE430_2:1440321_AT Microtubule associated serine/threonine kinase 2 (Mast2), mRNA mm
MOE430B:1441847_AT Microtubule associated serine/threonine kinase 2 (Mast2), mRNA mm
MOUSE430_2:1441847_AT Microtubule associated serine/threonine kinase 2 (Mast2), mRNA mm
MU19KSUBA:TC23567_S_AT Microtubule associated serine/threonine kinase 2 (Mast2), mRNA mm
MU19KSUBA:TC23568_S_AT Microtubule associated serine/threonine kinase 2 (Mast2), mRNA mm
RG-U34C:RC_AI230817_AT microtubule associated serine/threonine kinase 2 (predicted) rn
RAE230A:1388399_AT microtubule associated serine/threonine kinase 2 (predicted) rn
RAT230_2:1388399_AT microtubule associated serine/threonine kinase 2 (predicted) rn
RAE230B:1380873_AT microtubule associated serine/threonine kinase 2 (predicted) rn
RAT230_2:1380873_AT microtubule associated serine/threonine kinase 2 (predicted) rn
RAE230A:1375255_AT Microtubule associated serine/threonine kinase 2 (predicted) rn
RAT230_2:1375255_AT Microtubule associated serine/threonine kinase 2 (predicted) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5515 protein binding inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast NP_502161 protein KINase family member (kin-4) [Caenorhabditis elegans] 0.0
blast CAB05684 Hypothetical protein C10C6.1 [Caenorhabditis elegans] emb|CAJ31105.1| KIN-4 protein [Caenorhabditis elegans] 0.0
blast CAE62116 Hypothetical protein CBG06155 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 9.0E-67
hanks 1.9.3 AGC group; AGC Other; Mast205 1.0E-118
Protein Domains
Database ID Description E-Value
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 4.0E-8
Pfam IPR000719 EMBL-EBI Protein kinase 1.0E-81
Sequence
Target Sequence 
>C. ELEGANS:194184_X_AT
tttccaaaattctctttccaatctaaaacctagtcatttgacgtcacaatgcctttccaa
tctaattttgtaacctatctacactattttcttccttcataattctttcatctgttctta
atatatctaaccatttttcttctccctaaatatttccattctgttatattctagtttctc
ttccggctctgtccaccgtttccccgcaccacgcccattgataattagtaggcttcttgg
cctatgatta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTTCCAAAATTCTCTTTCCAATCTA 675 667 20 Antisense
TTTGACGTCACAATGCCTTTCCAAT 369 667 56 Antisense
AACCTATCTACACTATTTTCTTCCT 377 147 91 Antisense
TTTCTTCCTTCATAATTCTTTCATC 563 671 107 Antisense
TTCTTTCATCTGTTCTTAATATATC 202 691 122 Antisense
TATATCTAACCATTTTTCTTCTCCC 641 661 141 Antisense
TTCTTCTCCCTAAATATTTCCATTC 69 681 156 Antisense
ATTTCCATTCTGTTATATTCTAGTT 478 17 171 Antisense
TGTTATATTCTAGTTTCTCTTCCGG 602 561 181 Antisense
GCACCACGCCCATTGATAATTAGTA 322 313 225 Antisense
TAGTAGGCTTCTTGGCCTATGATTA 603 597 245 Antisense
Sequence Source Affymetrix Proprietary Database