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[194136_s_at]

Description ZK617.1B /REP_DB=WormBase Gene ID /WP=CE06635 /GEN=unc-22 /TR=Q23551 /GB=CAA98082.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Fibronectin type III domain (31 domains), IG (immunoglobulin) superfamily (18 domains), calcium-calmodulin dependent protein kinase
Cluster 4grp_high_8_8 > 32      6grp_total > 27      4grp_total > 47      6grp_cgc > 15      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 222
1 2 3 4 range
A 263
(3)
P 		92.1
(-1.9)
A 		54.1
(-3)
A 		98.8
(-1.7)
A 		209
B 227.8
(3)
P 		66.5
(-3)
P 		74.3
(-2.7)
P 		77
(-2.6)
A 		161
C 258.6
(3)
P 		96.8
(-1.5)
P 		40.7
(-3)
A 		67
(-2.3)
P 		218
avr 249.8
(3) 		85.1
(-2.1) 		56.4
(-3) 		80.9
(-2.2) 		193

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 130
1 2 3 4 5 6 range
A 67.6
(1.2)
P 		90
(3)
P 		17
(-2.8)
A 		33.5
(-1.5)
P 		15.1
(-3)
A 		53.8
(0.1)
A 		75
B 99.3
(3)
P 		49.2
(-1.1)
A 		53.1
(-0.8)
A 		82.9
(1.7)
P 		26.1
(-3)
A 		77.1
(1.2)
A 		73
C 144.6
(3)
P 		60.9
(-0.9)
A 		76.1
(-0.2)
P 		16.9
(-3)
A 		37.4
(-2)
A 		59.9
(-1)
A 		128
avr 103.8
(3) 		66.7
(0.1) 		48.7
(-1.3) 		44.4
(-1.6) 		26.2
(-3) 		63.6
(-0.1) 		78
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 84
1 2 3 4 range
A 95.7
(3)
P 		20
(-2.6)
A 		14.1
(-3)
A 		14.5
(-3)
A 		82
B 72.6
(3)
P 		16.4
(-3)
P 		17.2
(-2.9)
P 		16.4
(-3)
A 		56
C 85.6
(3)
P 		27.8
(-1.7)
P 		14.2
(-2.8)
A 		11.3
(-3)
P 		74
avr 84.6
(3) 		21.4
(-2.4) 		15.2
(-2.9) 		14.1
(-3) 		71

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 50
1 2 3 4 5 6 range
A 12.5
(-1.1)
P 		32
(3)
P 		3.7
(-3)
A 		8.5
(-2)
P 		4.6
(-2.8)
A 		13.1
(-1)
A 		28
B 34.5
(3)
P 		16.4
(-1.5)
A 		12.9
(-2.4)
A 		22
(-0.1)
P 		10.6
(-3)
A 		28.8
(1.6)
A 		24
C 53.6
(3)
P 		18.6
(-1.2)
A 		19.4
(-1.1)
P 		3.4
(-3)
A 		12.1
(-2)
A 		20
(-1)
A 		50
avr 33.5
(3) 		22.3
(0.2) 		12
(-2.3) 		11.3
(-2.5) 		9.1
(-3) 		20.6
(-0.2) 		24
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 194136_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8804
Sequence Type Exemplar sequence
Representative Public ID ZK617.1B NCBI
Target Description ZK617.1B /REP_DB=WormBase Gene ID /WP=CE06635 /GEN=unc-22 /TR=Q23551 /GB=CAA98082.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=Fibronectin type III domain (31 domains), IG (immunoglobulin) superfamily (18 domains), calcium-calmodulin dependent protein kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069872(11), NM_069873(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069872 NCBI Caenorhabditis elegans UNCoordinated family member (unc-22) (unc-22) mRNA, complete cds. 11/11 None
NM_069873 NCBI Caenorhabditis elegans UNCoordinated family member (unc-22) (unc-22) mRNA, complete cds. 11/11 None
ZK617.1a.2 ENSEMBL cdna:known chromosome:CEL140:IV:11972678:12010977:-1 gene:ZK617.1 11/11 None
ZK617.1a.1 ENSEMBL cdna:known chromosome:CEL140:IV:11972693:12010977:-1 gene:ZK617.1 11/11 None
ZK617.1b ENSEMBL cdna:known chromosome:CEL140:IV:11973621:12010850:-1 gene:ZK617.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000023400 8/11 Cross Hyb Matching Probes None
GENEFINDER00000023542 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11973626-12009442(-) 100.0 100.0
Public Domain and Genome References
Ensembl ZK617.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA98081 Hypothetical protein ZK617.1a [Caenorhabditis elegans] emb|CAA98064.2| Hypothetical protein ZK617.1a [Caenorhabditis elegans] ref|NP_502273.2| UNCoordinated family member (unc-22) [Caenorhabditis elegans] 0.0
blast CAA98082 Hypothetical protein ZK617.1b [Caenorhabditis elegans] emb|CAA98065.2| Hypothetical protein ZK617.1b [Caenorhabditis elegans] ref|NP_502274.2| UNCoordinated family member (unc-22) [Caenorhabditis elegans] 0.0
blast CAA33463 twitchin [Caenorhabditis elegans] 0.0
blast CAE62158 Hypothetical protein CBG06205 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 8.0E-63
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-63
hanks 2.1.17 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; TWITCH 1.0E-154
Protein Domains
Database ID Description E-Value
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.0E-7
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.2E-13
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.0E-16
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.2E-23
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.2E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.3E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 9.7E-19
Pfam IPR003961 EMBL-EBI Fibronectin, type III 5.8E-16
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.4E-13
Pfam IPR003961 EMBL-EBI Fibronectin, type III 4.9E-21
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.4E-18
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.4E-13
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.4E-13
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.4E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 3.4E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.4E-18
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.8E-11
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.8E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 7.1E-18
Pfam IPR003961 EMBL-EBI Fibronectin, type III 6.7E-19
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.2E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.7E-21
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.1E-22
Pfam IPR003961 EMBL-EBI Fibronectin, type III 3.7E-19
Pfam IPR003961 EMBL-EBI Fibronectin, type III 6.3E-22
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.6E-12
Pfam IPR003961 EMBL-EBI Fibronectin, type III 5.9E-20
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.1E-15
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.8E-18
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.3E-19
Pfam IPR003961 EMBL-EBI Fibronectin, type III 4.6E-15
Pfam IPR000719 EMBL-EBI Protein kinase 4.9E-78
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 5.2E-6
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0027
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 1.3E-4
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 5.7E-6
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 2.1E-5
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 6.6E-5
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0034
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0037
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.13
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0069
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0014
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.024
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 7.9E-4
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0020
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 5.0E-6
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.031
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 3.4E-7
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 4.6E-6
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 8.1E-9
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 1.5E-4
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 2.1E-4
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.0E-7
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.2E-13
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.0E-16
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.2E-23
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.2E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.3E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 9.7E-19
Pfam IPR003961 EMBL-EBI Fibronectin, type III 5.8E-16
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.4E-13
Pfam IPR003961 EMBL-EBI Fibronectin, type III 4.9E-21
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.4E-18
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.4E-13
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.4E-13
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.4E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 3.4E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.4E-18
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.8E-11
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.8E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 7.1E-18
Pfam IPR003961 EMBL-EBI Fibronectin, type III 6.7E-19
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.2E-17
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.7E-21
Pfam IPR003961 EMBL-EBI Fibronectin, type III 2.1E-22
Pfam IPR003961 EMBL-EBI Fibronectin, type III 3.7E-19
Pfam IPR003961 EMBL-EBI Fibronectin, type III 6.3E-22
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.6E-12
Pfam IPR003961 EMBL-EBI Fibronectin, type III 5.9E-20
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.1E-15
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.8E-18
Pfam IPR003961 EMBL-EBI Fibronectin, type III 1.3E-19
Pfam IPR003961 EMBL-EBI Fibronectin, type III 4.6E-15
Pfam IPR000719 EMBL-EBI Protein kinase 4.9E-78
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 5.7E-6
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 2.1E-5
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 6.6E-5
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0034
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0037
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.13
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0069
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0014
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.024
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 7.9E-4
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.0020
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 5.0E-6
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.031
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 3.4E-7
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 4.6E-6
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 8.1E-9
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 1.5E-4
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 2.1E-4
Sequence
Target Sequence 
>C. ELEGANS:194136_S_AT
cacttctcaatggacacgctggacaggctgttgaaagtgaacttcgtgtaacaaagcact
tgggaggagaaattgtgaataatggagagtcagttacatttgaagctagagtgcaaggaa
caccagaagaagtgttatggatgagaaatggacaagaattgacaaatggagataagacaa
gcatcagtcaagatggtgaaacactatctttcactatcaactcagcagacgcatcagatg
ccggacactaccaactggaagttcgttcaaaaggaacaaatctcgtatctgttgcatccc
tggtagtagttggagagaaagctgatcctccagtcaccaggctaccatcctctgtctctg
ctcctctcggcggatcaacagcatttacgattgaatttgaaaatgttgaaggtctgacag
tacaatggttccgcggatcggaaaaaattgaaaagaatgaacgggtcaaatcagtcaaga
ccggaaacacctttaagcttgacattaagaacgtcgaacaggacgacgacggcatctatg
tcgcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CACTTCTCAATGGACACGCTGGACA 448 197 20891 Antisense
TGGACACGCTGGACAGGCTGTTGAA 483 547 20901 Antisense
AACACTATCTTTCACTATCAACTCA 689 135 21090 Antisense
AACTCAGCAGACGCATCAGATGCCG 51 139 21109 Antisense
GCCGGACACTACCAACTGGAAGTTC 105 263 21130 Antisense
ACAAATCTCGTATCTGTTGCATCCC 433 111 21166 Antisense
CTGTTGCATCCCTGGTAGTAGTTGG 421 215 21179 Antisense
TCCTCTCGGCGGATCAACAGCATTT 344 591 21252 Antisense
CAGTACAATGGTTCCGCGGATCGGA 437 205 21308 Antisense
TCAAGACCGGAAACACCTTTAAGCT 529 627 21365 Antisense
GGACGACGACGGCATCTATGTCGCC 668 523 21411 Antisense
Sequence Source Affymetrix Proprietary Database