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[194130_s_at]

Description C01H6.5 /REP_DB=WormBase Gene ID /WP=CE24775 /GEN=nhr-23 /TR=Q17584 /GB=CAA95782.2 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
Cluster 6grp_high1_10_10 > 07      4grp_high_8_8 > 29      6grp_total > 08      4grp_total > 42      6grp_cgc > 0      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 91
1 2 3 4 range
A 68.2
(-3)
A 		143
(3)
P 		101
(-0.4)
P 		139.2
(2.7)
P 		75
B 52.3
(-3)
A 		116.1
(3)
P 		90.4
(0.6)
P 		57.5
(-2.5)
A 		64
C 83.6
(-1.1)
P 		129.1
(3)
P 		96.8
(0.1)
P 		62.1
(-3)
A 		67
avr 68
(-3) 		129.4
(3) 		96.1
(-0.3) 		86.3
(-1.2) 		61

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 86
1 2 3 4 5 6 range
A 147.2
(3)
P 		62.8
(-3)
A 		100.6
(-0.3)
P 		104.7
(-0)
P 		92.3
(-0.9)
P 		114.8
(0.7)
A 		84
B 140.4
(3)
P 		81.1
(-1.5)
M 		68.4
(-2.5)
P 		100.3
(-0.1)
P 		61.7
(-3)
P 		68.9
(-2.5)
P 		79
C 78.9
(-1)
A 		105.4
(3)
P 		99.9
(2.2)
A 		94.5
(1.3)
M 		90
(0.6)
A 		66.1
(-3)
P 		39
avr 122.2
(3) 		83.1
(-2.7) 		89.6
(-1.8) 		99.8
(-0.3) 		81.3
(-3) 		83.3
(-2.7) 		41
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 27
1 2 3 4 range
A 24.8
(-0.5)
A 		31
(3)
P 		26.4
(0.4)
P 		20.4
(-3)
P 		11
B 16.7
(-1.4)
A 		28.7
(3)
P 		20.9
(0.2)
P 		12.2
(-3)
A 		17
C 27.7
(0.9)
P 		37.1
(3)
P 		33.7
(2.2)
P 		10.5
(-3)
A 		27
avr 23.1
(-0.1) 		32.3
(3) 		27
(1.2) 		14.4
(-3) 		18

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 32
1 2 3 4 5 6 range
A 27.1
(2.1)
P 		22.3
(-2.6)
A 		21.9
(-3)
P 		26.6
(1.6)
P 		27.8
(2.8)
P 		28
(3)
A 		6
B 48.8
(3)
P 		27
(-1.1)
M 		16.6
(-3)
P 		26.6
(-1.1)
P 		25.1
(-1.4)
P 		25.7
(-1.3)
P 		32
C 29.2
(1.6)
A 		32.2
(3)
P 		25.4
(-0.1)
A 		19
(-3)
M 		29.1
(1.6)
A 		22.1
(-1.6)
P 		13
avr 35
(3) 		27.2
(-0.4) 		21.3
(-3) 		24.1
(-1.8) 		27.3
(-0.4) 		25.3
(-1.2) 		14
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 194130_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.942
Sequence Type Exemplar sequence
Representative Public ID C01H6.5 NCBI
Target Description C01H6.5 /REP_DB=WormBase Gene ID /WP=CE24775 /GEN=nhr-23 /TR=Q17584 /GB=CAA95782.2 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001025806(11), NM_001025804(11), NM_001025805(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001025806 NCBI Caenorhabditis elegans Nuclear Hormone Receptor family member (nhr-23) (nhr-23) mRNA, complete cds. 11/11 None
NM_001025804 NCBI Caenorhabditis elegans Nuclear Hormone Receptor family member (nhr-23) (nhr-23) mRNA, complete cds. 11/11 None
NM_001025805 NCBI Caenorhabditis elegans Nuclear Hormone Receptor family member (nhr-23) (nhr-23) mRNA, complete cds. 11/11 None
SNAP00000008119 ENSEMBL cdna:SNAP chromosome:CEL140:I:7226954:7229083:1 11/11 None
GENEFINDER00000008133 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7226954:7229083:1 11/11 None
C01H6.5c ENSEMBL cdna:known chromosome:CEL140:I:7222876:7229260:1 gene:C01H6.5 11/11 None
C01H6.5a ENSEMBL cdna:known chromosome:CEL140:I:7224915:7229937:1 gene:C01H6.5 11/11 A 
C01H6.5b.3 ENSEMBL cdna:known chromosome:CEL140:I:7226751:7229669:1 gene:C01H6.5 11/11 None
C01H6.5b.2 ENSEMBL cdna:known chromosome:CEL140:I:7226915:7229958:1 gene:C01H6.5 11/11 None
C01H6.5b.1 ENSEMBL cdna:known chromosome:CEL140:I:7226917:7229083:1 gene:C01H6.5 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7225023-7229014(+) 100.0 100.0
Public Domain and Genome References
Ensembl C01H6.5
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAI46548 Hypothetical protein C01H6.5c [Caenorhabditis elegans] ref|NP_001020977.1| Nuclear Hormone Receptor family member (nhr-23) [Caenorhabditis elegans] 0.0
blast CAA95782 Hypothetical protein C01H6.5a [Caenorhabditis elegans] ref|NP_001020975.1| Nuclear Hormone Receptor family member (nhr-23) [Caenorhabditis elegans] gb|AAK17974.1| nuclear receptor NHR-23 [Caenorhabditis elegans] sp|P41828|NHR23_CAEEL Nuclear hormone receptor family member nhr-23 (Steroid hormone receptor family member chr-3) 0.0
blast CAD30427 Hypothetical protein C01H6.5b [Caenorhabditis elegans] ref|NP_001020976.1| Nuclear Hormone Receptor family member (nhr-23) [Caenorhabditis elegans] gb|AAA96057.1| CHR3 gene product 0.0
blast T18848 hypothetical protein C01H6.5 - Caenorhabditis elegans 0.0
blast AAK17973 nuclear receptor NHR-23 [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 3.3E-22
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 3.3E-54
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 3.3E-22
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 3.3E-54
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 3.3E-22
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 3.3E-54
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 3.3E-22
Sequence
Target Sequence 
>C. ELEGANS:194130_S_AT
ggttgggagctcttcgctagggagctcaatccgcttattcaagcaattattgagtttgcc
aaaagtattgatggatttatgaatcttccgcaagaaacacagattcaattgctgaaggga
agcgtttttgagttatcactcgtttttgctgctatgtattacaatgtagacgcgcaggca
gtgtgcggtgaaaggtattctgttccatttgcatgcttgattgccgaagatgatgccgag
atgcaattgatcgttgaagttaataacactcttcaagaaattgttcatttacaaccgcat
caatccgaattagctcttcttgccgctggacttattctggagcaagtgtcttcttctcat
ggaattgggattcttgacactgcgacgattgccactgcagaaacactgaagaacgcgttg
taccaaagtgtcatgccaagaattggatgcatggaagacacgattcaccgaattcaagat
gttgagacaagaatcagacaaacagctcgtttgcatcaagaggctcttcaaaacttccga
atgtctgatccaac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGTTGGGAGCTCTTCGCTAGGGAGC 709 507 1168 Antisense
GCTAGGGAGCTCAATCCGCTTATTC 170 301 1183 Antisense
TCACTCGTTTTTGCTGCTATGTATT 469 627 1303 Antisense
GTAGACGCGCAGGCAGTGTGCGGTG 90 457 1333 Antisense
AGGTATTCTGTTCCATTTGCATGCT 623 57 1360 Antisense
TTCATTTACAACCGCATCAATCCGA 517 681 1451 Antisense
CAATCCGAATTAGCTCTTCTTGCCG 137 183 1468 Antisense
TGCCGCTGGACTTATTCTGGAGCAA 216 585 1488 Antisense
GGAGCAAGTGTCTTCTTCTCATGGA 22 521 1506 Antisense
GGATTCTTGACACTGCGACGATTGC 98 509 1535 Antisense
AAAACTTCCGAATGTCTGATCCAAC 95 131 1697 Antisense
Sequence Source Affymetrix Proprietary Database