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[194113_at] IG (immunoglobulin) superfamily (3 domains), tyrosine-protein kinase (KIN15/KIN16 subfamily) (2 domains)

Description F59F3.1 /REP_DB=WormBase Gene ID /WP=CE03437 /TR=Q21038 /GB=CAA91990.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=IG (immunoglobulin) superfamily (3 domains), tyrosine-protein kinase (KIN15-KIN16 subfamily) (2 domains)
Cluster 6grp_highest_10_10 > 75      6grp_high1_10_10 > 66      4grp_highest_8_8 > 46      4grp_high_8_8 > 10      6grp_highest_nonorm > 91      6grp_total > 57      4grp_total > 21      6grp_highest_sub > Cu      6grp_cgc > 38      6grp_high1_sub > Da      6grp_cgc_sub > Da      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 124
1 2 3 4 range
A 196.7
(0.3)
P 		136
(-2.6)
P 		128.1
(-3)
P 		251.7
(3)
P 		124
B 218.3
(3)
P 		207.6
(1.7)
P 		170.2
(-3)
P 		201
(0.8)
P 		48
C 239.8
(3)
P 		195.4
(-2.9)
P 		194.3
(-3)
P 		239.9
(3)
P 		46
avr 218.3
(1.9) 		179.7
(-1.6) 		164.2
(-3) 		230.9
(3) 		67

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 109
1 2 3 4 5 6 range
A 242.5
(1.8)
P 		199.2
(-1.9)
P 		189.7
(-2.7)
P 		186
(-3)
P 		212.6
(-0.8)
P 		257.2
(3)
P 		71
B 254.5
(1.9)
P 		196.1
(-2.2)
P 		208.8
(-1.3)
P 		259.5
(2.2)
P 		184
(-3)
P 		271
(3)
P 		87
C 162.2
(-3)
P 		237.4
(1.8)
P 		213.7
(0.3)
P 		209.5
(0)
P 		213.9
(0.3)
P 		256.8
(3)
P 		95
avr 219.7
(-1.3) 		210.9
(-2.2) 		204.1
(-2.9) 		218.3
(-1.5) 		203.5
(-3) 		261.7
(3) 		58
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 50
1 2 3 4 range
A 71.6
(3)
P 		29.5
(-3)
P 		33.5
(-2.4)
P 		36.8
(-2)
P 		42
B 69.6
(3)
P 		51.3
(-0.6)
P 		39.4
(-3)
P 		42.8
(-2.3)
P 		30
C 79.4
(3)
P 		56.2
(-0.6)
P 		67.7
(1.2)
P 		40.5
(-3)
P 		39
avr 73.5
(3) 		45.7
(-2) 		46.9
(-1.8) 		40
(-3) 		34

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 60
1 2 3 4 5 6 range
A 44.7
(-2.3)
P 		70.8
(3)
P 		41.3
(-3)
P 		47.2
(-1.8)
P 		64.1
(1.6)
P 		62.6
(1.3)
P 		30
B 88.5
(1.5)
P 		65.3
(-1.3)
P 		50.7
(-3)
P 		68.7
(-0.9)
P 		74.8
(-0.1)
P 		101.1
(3)
P 		50
C 60.1
(-0.5)
P 		72.4
(1.1)
P 		54.4
(-1.3)
P 		42.1
(-3)
P 		69.2
(0.7)
P 		86
(3)
P 		44
avr 64.4
(-0.3) 		69.5
(0.6) 		48.8
(-3) 		52.7
(-2.3) 		69.4
(0.6) 		83.2
(3) 		34
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 194113_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.15968
Sequence Type Exemplar sequence
Representative Public ID F59F3.1 NCBI
Target Description F59F3.1 /REP_DB=WormBase Gene ID /WP=CE03437 /TR=Q21038 /GB=CAA91990.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=IG (immunoglobulin) superfamily (3 domains), tyrosine-protein kinase (KIN15-KIN16 subfamily) (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077435(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077435 NCBI Caenorhabditis elegans VEGF (vascular endothelial growth factor) Receptor family member (ver-3) (ver-3) mRNA, complete cds. 11/11 None
GENEFINDER00000038687 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:10982351:10997288:1 11/11 None
SNAP00000038680 ENSEMBL cdna:SNAP chromosome:CEL140:X:10992453:10997288:1 11/11 None
F59F3.1 ENSEMBL cdna:known chromosome:CEL140:X:10992432:10997751:1 gene:F59F3.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:10992452-10997288(+) 100.0 100.0
Public Domain and Genome References
Gene Title IG (immunoglobulin) superfamily (3 domains), tyrosine-protein kinase (KIN15/KIN16 subfamily) (2 domains)
Gene Symbol ver-3
Ensembl F59F3.1
Entrez Gene 181289 Entrez gene
SwissProt Q21038 EMBL-EBI
WormBase CE03437 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1602441_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) cfa
CANINE:1582817_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) cfa
CANINE_2:CFA.19323.1.S1_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) cfa
CANINE_2:CFA.19323.1.S1_S_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) cfa
CANINE_2:CFA.3593.1.S1_S_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) cfa
CANINE_2:CFAAFFX.10969.1.S1_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) cfa
CANINE_2:CFAAFFX.10991.1.S1_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) cfa
CHICKEN:GGA.150.1.S1_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) gga
CHICKEN:GGA.150.2.S1_A_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) gga
CHICKEN:GGA.150.2.S2_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) gga
HG-U133_PLUS_2:210287_S_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133A:210287_S_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133A_2:210287_S_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95AV2:1545_G_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HC-G110:1545_G_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95AV2:1964_G_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HC-G110:1964_G_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95AV2:1567_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HC-G110:1567_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95AV2:990_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HC-G110:990_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95AV2:1963_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HC-G110:1963_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133_PLUS_2:204406_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133A:204406_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133A_2:204406_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HU35KSUBB:RC_AA194109_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HU35KSUBD:RC_T52674_S_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95AV2:991_G_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HC-G110:991_G_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HUGENEFL:X51602_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HUGENEFL:S77812_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
U133_X3P:G451321_3P_S_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
U133_X3P:G4503748_3P_AT fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133_PLUS_2:232809_S_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133B:232809_S_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HU35KSUBA:AA248994_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HU35KSUBA:RC_AA047437_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HU35KSUBB:RC_T23555_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
U133_X3P:HS.22968.2.S1_3P_A_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
U133_X3P:HS.22968.0.S1_3P_A_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133_PLUS_2:226497_S_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133B:226497_S_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133_PLUS_2:226498_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133B:226498_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95B:56189_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95B:56332_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95C:60318_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95D:87197_S_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133A_2:222033_S_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-FOCUS:222033_S_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133_PLUS_2:222033_S_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U133A:222033_S_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95C:54068_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HG-U95E:71869_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
HU35KSUBB:RC_AA121881_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
U133_X3P:HS.138671.2.A1_3P_A_AT Fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) hs
MG-U74AV2:98452_AT FMS-like tyrosine kinase 1 mm
MOUSE430_2:1451756_AT FMS-like tyrosine kinase 1 mm
MOE430A:1451756_AT FMS-like tyrosine kinase 1 mm
MOUSE430A_2:1451756_AT FMS-like tyrosine kinase 1 mm
MU11KSUBA:L07297_S_AT FMS-like tyrosine kinase 1 mm
MU11KSUBB:MSA.20425.0_S_AT FMS-like tyrosine kinase 1 mm
MU11KSUBB:MSA.19499.0_S_AT FMS-like tyrosine kinase 1 mm
MG-U74AV2:98453_AT FMS-like tyrosine kinase 1 mm
MG-U74CV2:167596_AT FMS-like tyrosine kinase 1 mm
MOE430A:1454037_A_AT FMS-like tyrosine kinase 1 mm
MOUSE430A_2:1454037_A_AT FMS-like tyrosine kinase 1 mm
MOUSE430_2:1454037_A_AT FMS-like tyrosine kinase 1 mm
MOE430A:1419300_AT FMS-like tyrosine kinase 1 mm
MOUSE430A_2:1419300_AT FMS-like tyrosine kinase 1 mm
MOUSE430_2:1419300_AT FMS-like tyrosine kinase 1 mm
MG-U74BV2:106503_AT FMS-like tyrosine kinase 1, mRNA (cDNA clone MGC:36074 IMAGE:5368921) mm
MOE430B:1440926_AT FMS-like tyrosine kinase 1, mRNA (cDNA clone MGC:36074 IMAGE:5368921) mm
MOUSE430_2:1440926_AT FMS-like tyrosine kinase 1, mRNA (cDNA clone MGC:36074 IMAGE:5368921) mm
MU19KSUBA:TC19263_S_AT FMS-like tyrosine kinase 1, mRNA (cDNA clone MGC:36074 IMAGE:5368921) mm
MU19KSUBA:TC21533_AT FMS-like tyrosine kinase 1, mRNA (cDNA clone MGC:36074 IMAGE:5368921) mm
MU19KSUBC:TC35392_AT FMS-like tyrosine kinase 1, mRNA (cDNA clone MGC:36074 IMAGE:5368921) mm
RG-U34A:D28498_AT FMS-like tyrosine kinase 1 rn
RAE230A:1370492_A_AT FMS-like tyrosine kinase 1 rn
RAT230_2:1370492_A_AT FMS-like tyrosine kinase 1 rn
RAE230A:1369087_AT FMS-like tyrosine kinase 1 rn
RAT230_2:1369087_AT FMS-like tyrosine kinase 1 rn
RAE230A:1375473_AT FMS-like tyrosine kinase 1 rn
RAT230_2:1375473_AT FMS-like tyrosine kinase 1 rn
RAE230A:1377113_AT FMS-like tyrosine kinase 1 rn
RAT230_2:1377113_AT FMS-like tyrosine kinase 1 rn
RAE230B:1383019_AT FMS-like tyrosine kinase 1 rn
RAT230_2:1383019_AT FMS-like tyrosine kinase 1 rn
RAE230B:1393179_AT FMS-like tyrosine kinase 1 rn
RAT230_2:1393179_AT FMS-like tyrosine kinase 1 rn
RAE230B:1393235_AT FMS-like tyrosine kinase 1 rn
RAT230_2:1393235_AT FMS-like tyrosine kinase 1 rn
RAE230B:1395197_AT FMS-like tyrosine kinase 1 rn
RAT230_2:1395197_AT FMS-like tyrosine kinase 1 rn
RG-U34A:RC_AA893612_AT FMS-like tyrosine kinase 1 rn
RG-U34B:RC_AI044948_AT FMS-like tyrosine kinase 1 rn
RG-U34B:RC_AI059968_AT FMS-like tyrosine kinase 1 rn
RG-U34C:RC_AI073212_AT FMS-like tyrosine kinase 1 rn
RG-U34C:RC_AI233956_S_AT FMS-like tyrosine kinase 1 rn
RG-U34A:RC_AI638974_AT FMS-like tyrosine kinase 1 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91990 Hypothetical protein F59F3.1 [Caenorhabditis elegans] ref|NP_509836.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-3) [Caenorhabditis elegans] 0.0
blast CAE70781 Hypothetical protein CBG17536 [Caenorhabditis briggsae] 0.0
blast CAA91991 Hypothetical protein F59F3.5 [Caenorhabditis elegans] ref|NP_509835.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-4) [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.2E-13
Pfam IPR000719 EMBL-EBI Protein kinase 1.8E-48
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.012
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.052
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 5.2E-5
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.12
Pfam IPR000719 EMBL-EBI Protein kinase 2.9E-15
Pfam IPR000719 EMBL-EBI Protein kinase 5.3E-39
Pfam IPR000719 EMBL-EBI Protein kinase 2.2E-13
Pfam IPR000719 EMBL-EBI Protein kinase 1.8E-48
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 2.8
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.38
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 1.2E-4
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 9.1E-7
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.012
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.052
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 5.2E-5
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.12
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509836.1 1 765-787
F59F3.1 1 765-787
GENEFINDER00000038687 3 641-660,772-794,1976-1998
SNAP00000038680 1 765-787
Sequence
Target Sequence 
>C. ELEGANS:194113_AT
agatgttccctgtgttcatcgtgatttggcttgccgaaatgttctcattaccaaaacgaa
aattgttcgtattgctgattttggtctttcgaagaaacatacgaataaaacctactatag
gacgaagaagagcaaggatactccactcccagttcgatggatgccgttagagtgtattga
agaatttaaattcactcaaaaatctgatgtctggtcttttggaatttgtctctatgagat
cttcacattaggcgggactccatatccaaattgtgatactttcaacgttattgaattcat
tcgaaatggaaatcgaaacaaacaaccagaatactgccatgacgaaatttatgagctaat
gaaagtgtgctggcaatttaatccaaaagatcgtccaacattcaatgattgtatcacgtt
ctttgaaaatcatatgcgagattcttctagccagtttcttgaacgcgtcgaaaacatgtt
gcacacggaaatgcaagaacagtcaaaacttgatgattggattcaagattcgcgtcctga
tgtccctaatgtgtcattccaaaagtctccga

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGATGTTCCCTGTGTTCATCGTGAT 48 67 3078 Antisense
TTTGGCTTGCCGAAATGTTCTCATT 176 667 3102 Antisense
GAAGAGCAAGGATACTCCACTCCCA 328 337 3204 Antisense
TCCACTCCCAGTTCGATGGATGCCG 190 589 3219 Antisense
AGATCTTCACATTAGGCGGGACTCC 75 67 3314 Antisense
GGCGGGACTCCATATCCAAATTGTG 291 539 3328 Antisense
CTAGCCAGTTTCTTGAACGCGTCGA 202 225 3524 Antisense
AACGCGTCGAAAACATGTTGCACAC 30 147 3539 Antisense
GATTCAAGATTCGCGTCCTGATGTC 150 431 3597 Antisense
GTCCTGATGTCCCTAATGTGTCATT 252 477 3611 Antisense
AATGTGTCATTCCAAAAGTCTCCGA 164 163 3625 Antisense
Sequence Source Affymetrix Proprietary Database