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[194098_at] Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)

Description ZK1037.5 /REP_DB=WormBase Gene ID /WP=CE16757 /TR=O45987 /GB=CAB03504.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
Cluster 6grp_total > 99      4grp_total > 34      6grp_cgc > 89      6grp_total_sub > Increase      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 17
1 2 3 4 range
A 1.6
(-3)
A 		1.5
(-3)
A 		3.3
(-2.3)
A 		16.9
(3)
A 		15
B 1.6
(-3)
A 		9.8
(2.6)
A 		10.4
(3)
A 		1.9
(-2.8)
A 		9
C 3.4
(-3)
A 		18.4
(3)
A 		4
(-2.8)
A 		9.6
(-0.5)
A 		15
avr 2.2
(-3) 		9.9
(3) 		5.9
(-0.1) 		9.5
(2.7) 		8

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 21
1 2 3 4 5 6 range
A 6
(3)
A 		2.6
(-1.5)
A 		2.8
(-1.3)
A 		1.5
(-3)
A 		3.4
(-0.5)
A 		2.9
(-1.1)
A 		5
B 2.2
(-1.2)
A 		2.3
(-0.9)
A 		1.5
(-3)
A 		3.8
(3)
A 		1.9
(-2)
A 		1.9
(-2)
A 		2
C 2
(-2.9)
A 		4.1
(-2.3)
A 		2.5
(-2.7)
A 		1.6
(-3)
A 		22.1
(3)
A 		16.3
(1.3)
A 		21
avr 3.4
(-2) 		3
(-2.4) 		2.3
(-3) 		2.3
(-3) 		9.1
(3) 		7
(1.1) 		7
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 5
1 2 3 4 range
A 0.6
(-2.2)
A 		0.3
(-3)
A 		0.9
(-1.4)
A 		2.5
(3)
A 		2
B 0.5
(-2.7)
A 		2.4
(3)
A 		2.4
(3)
A 		0.4
(-3)
A 		2
C 1.1
(-3)
A 		5.3
(3)
A 		1.4
(-2.6)
A 		1.6
(-2.3)
A 		4
avr 0.7
(-3) 		2.7
(3) 		1.6
(-0.3) 		1.5
(-0.6) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 7
1 2 3 4 5 6 range
A 1.1
(3)
A 		0.9
(1.3)
A 		0.6
(-1.3)
A 		0.4
(-3)
A 		1
(2.1)
A 		0.7
(-0.4)
A 		1
B 0.8
(1)
A 		0.8
(1)
A 		0.4
(-3)
A 		1
(3)
A 		0.8
(1)
A 		0.7
(-0)
A 		1
C 0.8
(-2.6)
A 		1.3
(-2.1)
A 		0.6
(-2.7)
A 		0.3
(-3)
A 		7.2
(3)
A 		5.5
(1.5)
A 		7
avr 0.9
(-2) 		1
(-1.8) 		0.5
(-3) 		0.6
(-2.8) 		3
(3) 		2.3
(1.3) 		3
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 194098_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13043
Sequence Type Exemplar sequence
Representative Public ID ZK1037.5 NCBI
Target Description ZK1037.5 /REP_DB=WormBase Gene ID /WP=CE16757 /TR=O45987 /GB=CAB03504.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074397(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074397 NCBI Caenorhabditis elegans ZK1037.5 (ZK1037.5) mRNA, complete cds. 11/11 None
GENEFINDER00000019051 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:15326439:15327937:1 11/11 None
ZK1037.5 ENSEMBL cdna:known chromosome:CEL140:V:15326439:15327937:1 gene:ZK1037.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:15326438-15327937(+) 100.0 100.0
Public Domain and Genome References
Gene Title Ligand-binding domain of nuclear hormone receptors, Zinc finger, C4 type (two domains)
Gene Symbol nhr-247
Ensembl ZK1037.5
Entrez Gene 191500 Entrez gene
SwissProt O45987 EMBL-EBI
WormBase CE16757 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5634 nucleus inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3677 DNA binding inferred from electronic annotation QuickGO AmiGO
3700 transcription factor activity inferred from electronic annotation QuickGO AmiGO
3707 steroid hormone receptor activity inferred from electronic annotation QuickGO AmiGO
4879 ligand-dependent nuclear receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03504 Hypothetical protein ZK1037.5 [Caenorhabditis elegans] ref|NP_506798.1| ZK1037.5 [Caenorhabditis elegans] 0.0
blast CAB03503 Hypothetical protein ZK1037.4 [Caenorhabditis elegans] ref|NP_506797.1| ZK1037.4 [Caenorhabditis elegans] 2.0E-82
blast CAE65412 Hypothetical protein CBG10365 [Caenorhabditis briggsae] 1.0E-77
Protein Domains
Database ID Description E-Value
Pfam IPR000536 EMBL-EBI Ligand-binding domain of nuclear hormone receptor 5.5E-28
Pfam IPR001628 EMBL-EBI Zn-finger, C4-type steroid receptor 6.3E-20
Sequence
Target Sequence 
>C. ELEGANS:194098_AT
gaagcaggcagattcagatgacgtcagatttgtaatgagcctcggattccaaaatgcctt
gagctgggcgaatcattttgaaacatttacgaaattgtctgaagatcaaaaggcattagt
tatgtcagagtttggaattgcatttattctaatagagcaagctttcaaaacagcagaaga
taccgaggaagggtgctggatactgcagaatgacacgtttttagaaatttcagatactag
aaatgttcagggacagaagagaattaactctgagtttgcggatttcttatttaagactct
gtcggagccaattaggagtttgcaactagacaagtttgaatgtgtggttttgaaaacaat
ggtgcttttatcacagtcatttcccagtcaactctacctgccacgtttcgaggaaaaccg
gaaaaactgcatgaaaacgttgatgaaatacgaactacgcaaattcccagaaacaggatc
tcagagatttggagaaataatattgttactgagttctgtgagatgtgcggtaaagcagtt
atacaaccataccaagcgatcagatctc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAGCAGGCAGATTCAGATGACGTC 682 341 408 Antisense
GACGTCAGATTTGTAATGAGCCTCG 108 379 427 Antisense
GAGCCTCGGATTCCAAAATGCCTTG 652 383 444 Antisense
ATGCCTTGAGCTGGGCGAATCATTT 76 41 461 Antisense
GGATACTGCAGAATGACACGTTTTT 381 511 605 Antisense
AACTCTGAGTTTGCGGATTTCTTAT 527 137 673 Antisense
AAGACTCTGTCGGAGCCAATTAGGA 393 153 700 Antisense
TTATCACAGTCATTTCCCAGTCAAC 579 679 775 Antisense
TCTACCTGCCACGTTTCGAGGAAAA 260 613 800 Antisense
AATACGAACTACGCAAATTCCCAGA 280 171 854 Antisense
CAACCATACCAAGCGATCAGATCTC 276 187 951 Antisense
Sequence Source Affymetrix Proprietary Database