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[194089_s_at] mechanosensory protein (mec-9)

Description C50H2.3B /REP_DB=WormBase Gene ID /WP=CE08916 /GEN=mec-9 /TR=O17692 /GB=CAA98256.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=EGF-like domain (3 domains), Kunitz-Bovine pancreatic trypsin inhibitor domain
Cluster 6grp_high1_10_10 > 13      4grp_high_8_8 > 34      6grp_total > 14      4grp_total > 45      6grp_cgc > 33      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 175
1 2 3 4 range
A 148.7
(1)
P 		173.6
(3)
P 		99.4
(-3)
A 		132.3
(-0.3)
P 		74
B 168.5
(3)
P 		86.6
(-1.3)
P 		100.3
(-0.6)
A 		54.3
(-3)
P 		114
C 229.6
(3)
P 		146.2
(-0.1)
P 		68.5
(-3)
P 		115
(-1.3)
P 		161
avr 182.3
(3) 		135.5
(-0) 		89.4
(-3) 		100.5
(-2.3) 		93

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 173
1 2 3 4 5 6 range
A 136.8
(-0.5)
P 		234.8
(3)
P 		130.9
(-0.7)
P 		121.7
(-1.1)
P 		68.4
(-3)
A 		71.8
(-2.9)
A 		166
B 200.8
(3)
P 		191.2
(2.4)
P 		96.3
(-3)
P 		120.1
(-1.6)
P 		104.9
(-2.5)
P 		115.6
(-1.9)
P 		105
C 193.6
(3)
P 		171.4
(2)
P 		171.6
(2)
P 		142.5
(0.7)
P 		81.8
(-2.1)
P 		62.1
(-3)
P 		132
avr 177.1
(1.9) 		199.1
(3) 		132.9
(-0.4) 		128.1
(-0.7) 		85
(-2.9) 		83.2
(-3) 		116
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 64
1 2 3 4 range
A 54.2
(3)
P 		37.7
(0.2)
P 		26
(-1.9)
A 		19.4
(-3)
P 		35
B 53.7
(3)
P 		21.4
(-1.6)
P 		23.2
(-1.3)
A 		11.6
(-3)
P 		42
C 76
(3)
P 		42
(-0.6)
P 		23.9
(-2.5)
P 		19.4
(-3)
P 		57
avr 61.3
(3) 		33.7
(-0.7) 		24.4
(-2) 		16.8
(-3) 		45

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 66
1 2 3 4 5 6 range
A 25.2
(-2.3)
P 		83.5
(3)
P 		28.5
(-2)
P 		30.9
(-1.8)
P 		20.6
(-2.7)
A 		17.5
(-3)
A 		66
B 69.9
(3)
P 		63.6
(2.2)
P 		23.4
(-3)
P 		31.8
(-1.9)
P 		42.6
(-0.5)
P 		43.1
(-0.5)
P 		47
C 71.8
(3)
P 		52.3
(0.7)
P 		43.7
(-0.3)
P 		28.7
(-2.1)
P 		26.5
(-2.3)
P 		20.8
(-3)
P 		51
avr 55.6
(1.3) 		66.5
(3) 		31.9
(-2.3) 		30.5
(-2.5) 		29.9
(-2.6) 		27.1
(-3) 		39
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 194089_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11874
Sequence Type Exemplar sequence
Representative Public ID C50H2.3B NCBI
Target Description C50H2.3B /REP_DB=WormBase Gene ID /WP=CE08916 /GEN=mec-9 /TR=O17692 /GB=CAA98256.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=EGF-like domain (3 domains), Kunitz-Bovine pancreatic trypsin inhibitor domain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001028559(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001028559 NCBI Caenorhabditis elegans MEChanosensory abnormality family member (mec-9) (mec-9) mRNA, complete cds. 11/11 None
SNAP00000033465 ENSEMBL cdna:SNAP chromosome:CEL140:V:9908494:9913169:-1 11/11 None
GENEFINDER00000033477 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:9910488:9913169:-1 11/11 None
C50H2.3a ENSEMBL cdna:known chromosome:CEL140:V:9910214:9917669:-1 gene:C50H2.3 11/11 None
C50H2.3b ENSEMBL cdna:known chromosome:CEL140:V:9910488:9913091:-1 gene:C50H2.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:9910487-9913091(-) 92.38 100.0
Public Domain and Genome References
Gene Title mechanosensory protein (mec-9)
Gene Symbol mec-9
Ensembl C50H2.3
Entrez Gene 179382 Entrez gene
SwissProt Q18761 EMBL-EBI
WormBase CE05481 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
5509 calcium ion binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA98251 Hypothetical protein C50H2.3 [Caenorhabditis elegans] ref|NP_001023730.1| MEChanosensory abnormality family member (mec-9) [Caenorhabditis elegans] 0.0
blast AAA96507 MEC-9L gb|AAA96506.1| MEC-9L 0.0
blast CAE72279 Hypothetical protein CBG19401 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR006209 EMBL-EBI EGF-like domain 6.7E-7
Pfam IPR006209 EMBL-EBI EGF-like domain 1.3E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 1.9E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 9.7E-11
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.8E-22
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 4.8E-24
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 1.6E-7
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 6.1E-7
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 3.0E-19
Pfam IPR006209 EMBL-EBI EGF-like domain 1.3E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 1.9E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 9.7E-11
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 6.1E-7
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 3.0E-19
Pfam IPR006209 EMBL-EBI EGF-like domain 1.3E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 1.9E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 9.7E-11
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 6.1E-7
Pfam IPR002223 EMBL-EBI Pancreatic trypsin inhibitor (Kunitz) 3.0E-19
Pfam IPR006209 EMBL-EBI EGF-like domain 1.3E-8
Pfam IPR006209 EMBL-EBI EGF-like domain 1.9E-6
Pfam IPR006209 EMBL-EBI EGF-like domain 9.7E-11
Sequence
Target Sequence 
>C. ELEGANS:194089_S_AT
gagaccatgtgaatcaaatccttgtctgaataatggaacatgtcgtaccacaaaagggta
cagtacctatttctgtgaatgcgcaaatggtttcggtggaaagaactgtgacgtctcaat
cggcaacacgcctccagaagagaaatttggaaaaaatgtagaacagatttctagcggaaa
ggaagagtggattgcacaaatgcgacaaagattaaaagaaaccggtggtggaattggtgg
agcgtctggatctggattgaaatcagaaaatggaacaatgggaggatcttctggagagaa
atcaggagaaaagaaatcaggaaaaaataaaaagagcaaagccactcaggtcgcagatga
accatataaagatccagcaacacgaaaacgagaacgtgaagaacgagaaaagaaagaagc
tgaaatacaggcagcagaagaagaagaaaaacagagaaaagagtatgaagaagacgctca
acgaaaaaaagctgaagaaatggaattagaagctaaaaaggcattagaagcagcaaattt
tggattaaaaactgatttttcgatgtccctgct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAGACCATGTGAATCAAATCCTTGT 264 395 912 Antisense
GGAACATGTCGTACCACAAAAGGGT 128 529 946 Antisense
AGTACCTATTTCTGTGAATGCGCAA 125 63 973 Antisense
GAATGCGCAAATGGTTTCGGTGGAA 285 331 988 Antisense
GAACTGTGACGTCTCAATCGGCAAC 414 347 1014 Antisense
TCGGCAACACGCCTCCAGAAGAGAA 681 605 1031 Antisense
ATTGGTGGAGCGTCTGGATCTGGAT 681 3 1144 Antisense
AACAATGGGAGGATCTTCTGGAGAG 544 133 1185 Antisense
AAAGAGCAAAGCCACTCAGGTCGCA 541 119 1242 Antisense
GCCACTCAGGTCGCAGATGAACCAT 384 279 1252 Antisense
AAACTGATTTTTCGATGTCCCTGCT 571 127 1460 Antisense
Sequence Source Affymetrix Proprietary Database