[Home] | [Total List]

[194087_s_at] Phorbol esters/diacylglycerol binding domain (C1 domain) ; Eukaryotic protein kinase domain

Description W09C5.5 /REP_DB=WormBase Gene ID /WP=CE20167 /TR=Q9XUJ7 /GB=CAB04940.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Phorbol esters-diacylglycerol binding domain (C1 domain) ; Eukaryotic protein kinase domain
Cluster 6grp_highest_10_10 > 21      6grp_high1_10_10 > 12      4grp_highest_8_8 > 41      4grp_high_8_8 > 50      6grp_highest_nonorm > 41      6grp_total > 23      4grp_total > 62      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 433
1 2 3 4 range
A 894.5
(3)
P 		659.4
(-0.3)
P 		708.5
(0.4)
P 		461.5
(-3)
P 		433
B 888.8
(3)
P 		815.7
(1.8)
P 		823.8
(1.9)
P 		533.9
(-3)
P 		355
C 845.1
(3)
P 		717.8
(-1.1)
P 		768.1
(0.5)
P 		658.8
(-3)
P 		186
avr 876.1
(3) 		731
(0.3) 		766.8
(1) 		551.4
(-3) 		325

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 456
1 2 3 4 5 6 range
A 886.2
(3)
P 		713
(0.7)
P 		612.1
(-0.6)
P 		679.7
(0.3)
P 		637.5
(-0.3)
P 		430.4
(-3)
P 		456
B 808.6
(3)
P 		719.5
(1.6)
P 		794.1
(2.8)
P 		660.4
(0.6)
P 		546.6
(-1.2)
P 		433.6
(-3)
P 		375
C 850.4
(3)
P 		766.4
(1.7)
P 		791.1
(2)
P 		594.1
(-1.1)
P 		578.1
(-1.4)
P 		476.1
(-3)
P 		374
avr 848.4
(3) 		733
(1.3) 		732.4
(1.3) 		644.7
(-0) 		587.4
(-0.9) 		446.7
(-3) 		402
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 258
1 2 3 4 range
A 325.7
(3)
P 		143.1
(-1.2)
P 		185.2
(-0.3)
P 		67.6
(-3)
P 		258
B 283.4
(3)
P 		201.5
(0.1)
P 		190.9
(-0.3)
P 		113.8
(-3)
P 		170
C 279.7
(3)
P 		206.4
(0.4)
P 		267.7
(2.6)
P 		111.1
(-3)
P 		169
avr 296.3
(3) 		183.7
(-0.4) 		214.6
(0.5) 		97.5
(-3) 		199

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 210
1 2 3 4 5 6 range
A 163.4
(-0.6)
P 		253.6
(3)
P 		133.3
(-1.9)
P 		172.4
(-0.3)
P 		192.4
(0.5)
P 		104.8
(-3)
P 		149
B 281.3
(3)
P 		239.5
(0.9)
P 		192.8
(-1.4)
P 		174.9
(-2.3)
P 		222.1
(0)
P 		161.7
(-3)
P 		120
C 315.2
(3)
P 		233.8
(0.5)
P 		201.3
(-0.5)
P 		119.5
(-3)
P 		187.1
(-0.9)
P 		159.4
(-1.8)
P 		196
avr 253.3
(3) 		242.3
(2.4) 		175.8
(-1.2) 		155.6
(-2.3) 		200.5
(0.2) 		142
(-3) 		111
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 194087_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.1796
Sequence Type Exemplar sequence
Representative Public ID W09C5.5 NCBI
Target Description W09C5.5 /REP_DB=WormBase Gene ID /WP=CE20167 /TR=Q9XUJ7 /GB=CAB04940.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Phorbol esters-diacylglycerol binding domain (C1 domain) ; Eukaryotic protein kinase domain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060989(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060989 NCBI Caenorhabditis elegans W09C5.5 (W09C5.5) mRNA, complete cds. 11/11 None
SNAP00000012967 ENSEMBL cdna:SNAP chromosome:CEL140:I:13648553:13660679:-1 9/11 None
GENEFINDER00000013012 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:13648553:13656515:-1 11/11 None
W09C5.5 ENSEMBL cdna:known chromosome:CEL140:I:13648441:13656523:-1 gene:W09C5.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:13648483-13656446(-) 100.0 100.0
Public Domain and Genome References
Gene Title Phorbol esters/diacylglycerol binding domain (C1 domain) ; Eukaryotic protein kinase domain
Ensembl W09C5.5
Entrez Gene 173234 Entrez gene
SwissProt Q9XUJ7 EMBL-EBI
WormBase CE20167 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
7242 intracellular signaling cascade inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04940 Hypothetical protein W09C5.5 [Caenorhabditis elegans] ref|NP_493390.1| W09C5.5 [Caenorhabditis elegans] 0.0
blast CAE72586 Hypothetical protein CBG19775 [Caenorhabditis briggsae] 0.0
blast EAA06222 ENSANGP00000004713 [Anopheles gambiae str. PEST] ref|XP_311085.2| ENSANGP00000004713 [Anopheles gambiae str. PEST] 1.0E-142
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 5.0E-60
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-68
hanks 1.2.18 AGC group; AGC I Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family; PKCm 2.0E-72
hanks 1.2.18 AGC group; AGC I Diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family; PKCm 8.0E-89
Protein Domains
Database ID Description E-Value
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 1.9E-16
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 4.4E-15
Pfam IPR000719 EMBL-EBI Protein kinase 8.6E-66
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 1.9E-16
Pfam IPR002219 EMBL-EBI Protein kinase C, phorbol ester/diacylglycerol binding 4.4E-15
Pfam IPR000719 EMBL-EBI Protein kinase 3.0E-76
Sequence
Target Sequence 
>C. ELEGANS:194087_S_AT
tcaagaacttggtcgactcaactcccgagccacaaaattcctgctcgtccaaatcctatg
cgccttgaaataccttcacgatcagggaattgcacattgtgaccttaaaccggaaaacgt
actcctctcggatatgggatcaaactttccgcagacaaagatctgtgactttggctacgc
ccgattcattccagagtcacagtttaggaagactgttgtcggcacacctgcctaccttcc
acctgaagtgttacagagaaaaggatataataagtctctggatatgtggtctgttggtgt
cattatttatgtcacgttatctggaactttcccgtttaatgagggagaggagatatcgga
gcaaatccaaaatgcgtcctttatgttccctacggagccatggagtgaagtagagcctct
ggcagttgatttgattcaaaaattgctgaaagtggagatcgaagctcgaatgtcaatcga
acagtgtctggatcatggatggttgaaaggagaacaactgtatcgagatttgagggattt
ggaggttcgactaaacacgccgagatacctgacaagt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCAAGAACTTGGTCGACTCAACTCC 53 629 1563 Antisense
GAGCCACAAAATTCCTGCTCGTCCA 459 385 1589 Antisense
AATCCTATGCGCCTTGAAATACCTT 456 165 1614 Antisense
AACGTACTCCTCTCGGATATGGGAT 670 141 1678 Antisense
CCCGATTCATTCCAGAGTCACAGTT 644 259 1742 Antisense
TAGGAAGACTGTTGTCGGCACACCT 243 653 1767 Antisense
GCCTACCTTCCACCTGAAGTGTTAC 441 279 1792 Antisense
GTCACGTTATCTGGAACTTTCCCGT 154 459 1873 Antisense
CCAAAATGCGTCCTTTATGTTCCCT 564 273 1929 Antisense
TATGTTCCCTACGGAGCCATGGAGT 546 655 1944 Antisense
AAACACGCCGAGATACCTGACAAGT 150 129 2115 Antisense
Sequence Source Affymetrix Proprietary Database