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[194085_at] IG (immunoglobulin) superfamily (3 domains), tyrosine-protein kinase (KIN15/KIN16 subfamily)

Description F59F3.5 /REP_DB=WormBase Gene ID /WP=CE03440 /TR=Q21041 /GB=CAA91991.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=IG (immunoglobulin) superfamily (3 domains), tyrosine-protein kinase (KIN15-KIN16 subfamily)
Cluster 4grp_high_8_8 > 20      6grp_total > 20      4grp_total > 20      6grp_cgc > 72      6grp_cgc_sub > 02      6grp_total_sub > Hat      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 91
1 2 3 4 range
A 80.8
(-0.6)
P 		79.6
(-0.7)
P 		60.2
(-3)
P 		111.4
(3)
P 		51
B 85.5
(3)
P 		82.7
(2.6)
P 		63.4
(0.1)
P 		39.9
(-3)
A 		46
C 66.3
(-2.2)
P 		69.2
(-2)
M 		56.3
(-3)
P 		131.1
(3)
P 		75
avr 77.5
(0.1) 		77.2
(0) 		60
(-3) 		94.1
(3) 		34

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 89
1 2 3 4 5 6 range
A 54.2
(-2.4)
A 		111.7
(2.1)
P 		122.9
(3)
P 		82.1
(-0.2)
P 		46.1
(-3)
P 		51.5
(-2.6)
A 		77
B 72.5
(-0.2)
P 		112.5
(3)
P 		58.7
(-1.3)
P 		77.2
(0.2)
P 		38
(-3)
A 		51.9
(-1.9)
A 		75
C 45.1
(-2.2)
A 		112.7
(2.4)
P 		121.9
(3)
P 		77
(-0.1)
A 		72.6
(-0.3)
P 		33.6
(-3)
A 		88
avr 57.3
(-2) 		112.3
(3) 		101.2
(2) 		78.8
(-0) 		52.2
(-2.4) 		45.7
(-3) 		67
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 21
1 2 3 4 range
A 29.4
(3)
P 		17.3
(-2.3)
P 		15.7
(-3)
P 		16.3
(-2.7)
P 		14
B 27.3
(3)
P 		20.4
(0.8)
P 		14.7
(-1)
P 		8.5
(-3)
A 		19
C 21.9
(2.5)
P 		19.9
(-2.3)
M 		19.6
(-3)
P 		22.1
(3)
P 		3
avr 26.2
(3) 		19.2
(-1) 		16.7
(-2.4) 		15.6
(-3) 		11

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 30
1 2 3 4 5 6 range
A 10
(-3)
A 		39.7
(3)
P 		26.8
(0.4)
P 		20.8
(-0.8)
P 		13.9
(-2.2)
P 		12.5
(-2.5)
A 		30
B 25.2
(-0.2)
P 		37.4
(3)
P 		14.2
(-3)
P 		20.5
(-1.4)
P 		15.5
(-2.7)
A 		19.4
(-1.7)
A 		23
C 16.7
(-1.6)
A 		34.4
(3)
P 		31
(2.1)
P 		15.5
(-1.9)
A 		23.5
(0.2)
P 		11.3
(-3)
A 		23
avr 17.3
(-2.2) 		37.2
(3) 		24
(-0.5) 		18.9
(-1.8) 		17.6
(-2.2) 		14.4
(-3) 		23
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 194085_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17183
Sequence Type Exemplar sequence
Representative Public ID F59F3.5 NCBI
Target Description F59F3.5 /REP_DB=WormBase Gene ID /WP=CE03440 /TR=Q21041 /GB=CAA91991.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=IG (immunoglobulin) superfamily (3 domains), tyrosine-protein kinase (KIN15-KIN16 subfamily)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077434(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077434 NCBI Caenorhabditis elegans VEGF (vascular endothelial growth factor) Receptor family member (ver-4) (ver-4) mRNA, complete cds. 11/11 None
SNAP00000038679 ENSEMBL cdna:SNAP chromosome:CEL140:X:10982351:10987472:1 9/11 None
GENEFINDER00000038687 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:10982351:10997288:1 11/11 None
F59F3.5 ENSEMBL cdna:known chromosome:CEL140:X:10982351:10987815:1 gene:F59F3.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:10982350-10987815(+) 100.0 100.0
Public Domain and Genome References
Gene Title IG (immunoglobulin) superfamily (3 domains), tyrosine-protein kinase (KIN15/KIN16 subfamily)
Gene Symbol ver-4
Ensembl F59F3.5
Entrez Gene 186632 Entrez gene
SwissProt Q21041 EMBL-EBI
WormBase CE03440 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91991 Hypothetical protein F59F3.5 [Caenorhabditis elegans] ref|NP_509835.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-4) [Caenorhabditis elegans] 0.0
blast CAA91990 Hypothetical protein F59F3.1 [Caenorhabditis elegans] ref|NP_509836.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-3) [Caenorhabditis elegans] 0.0
blast CAE70781 Hypothetical protein CBG17536 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 2.9E-15
Pfam IPR000719 EMBL-EBI Protein kinase 5.3E-39
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 2.8
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.38
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 1.2E-4
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 9.1E-7
Pfam IPR000719 EMBL-EBI Protein kinase 2.9E-15
Pfam IPR000719 EMBL-EBI Protein kinase 4.1E-29
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 1.2E-4
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 9.1E-7
Pfam IPR000719 EMBL-EBI Protein kinase 2.2E-13
Pfam IPR000719 EMBL-EBI Protein kinase 1.8E-48
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.012
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.052
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 5.2E-5
Pfam IPR007110 EMBL-EBI Immunoglobulin-like 0.12
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509835.1 1 772-794
F59F3.5 1 772-794
SNAP00000038679 1 713-735
GENEFINDER00000038687 3 641-660,772-794,1976-1998
Sequence
Target Sequence 
>C. ELEGANS:194085_AT
atgaattcaattccctatgcacctctgatttattgtctattggtttacaaattgcaaatg
gaatggattggttggcaaatattccgtgtgtacatcgtgatttagcctgtcgaaacgttc
ttatttccaaaaccaaaatcattcgaatagctgactttggtctggcaaaaaagcacaccg
ataaagcttattacagagtaagagaaagtctagatacaccacttccagttcgttggatgc
ctttggaatccattacagatttaacgttcacacaaaaatcggatgtgtggtcttatggaa
tttgtttatatgaaatttttacacttggaggaacaccatatcccgactgtcctaatttta
gtcttgtagagtacataaaaacgggaaatattaacaaacgaccatctaactgtcataagg
acgtatataaaattatgaaaatgtgttggcaagcgtctccggatgaccggccaactttcg
ctgaatgcatcaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATGAATTCAATTCCCTATGCACCTC 245 43 2987 Antisense
TATGCACCTCTGATTTATTGTCTAT 310 657 3002 Antisense
GGTTGGCAAATATTCCGTGTGTACA 59 509 3056 Antisense
GTACATCGTGATTTAGCCTGTCGAA 250 461 3076 Antisense
GCCTGTCGAAACGTTCTTATTTCCA 233 281 3091 Antisense
CATTCGAATAGCTGACTTTGGTCTG 275 215 3126 Antisense
GAAAGTCTAGATACACCACTTCCAG 331 361 3190 Antisense
ACCACTTCCAGTTCGTTGGATGCCT 79 85 3204 Antisense
ACCATATCCCGACTGTCCTAATTTT 215 87 3321 Antisense
AAAATGTGTTGGCAAGCGTCTCCGG 323 131 3424 Antisense
GGCCAACTTTCGCTGAATGCATCAA 28 545 3455 Antisense
Sequence Source Affymetrix Proprietary Database