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[194079_at] Alcohol/other dehydrogenases, short chain type, Short chain dehydrogenase/reductase C-terminus

Description Y39A1A.11 /REP_DB=WormBase Gene ID /WP=CE19130 /TR=Q9XX28 /GB=CAA21012.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Alcohol-other dehydrogenases, short chain type, Short chain dehydrogenase-reductase C-terminus
Cluster 6grp_total > 86      4grp_total > 16      6grp_cgc > 68      6grp_cgc_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 761
1 2 3 4 range
A 20
(-3)
A 		174.2
(-1.8)
A 		303.1
(-0.8)
A 		780.5
(3)
P 		761
B 36.9
(-3)
A 		39.5
(-3)
A 		239.4
(-0.7)
A 		556.1
(3)
P 		519
C 30.3
(-3)
A 		127
(-2)
A 		193
(-1.3)
A 		599.4
(3)
P 		569
avr 29.1
(-3) 		113.6
(-2.2) 		245.2
(-0.9) 		645.3
(3) 		616

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 747
1 2 3 4 5 6 range
A 70.9
(-2.7)
A 		39.6
(-3)
A 		164.7
(-1.9)
A 		303.9
(-0.6)
P 		491.3
(1.1)
P 		704.9
(3)
P 		665
B 18.7
(-3)
A 		76
(-2.5)
A 		161.5
(-1.9)
A 		293.7
(-0.8)
P 		435.6
(0.3)
P 		765.6
(3)
P 		747
C 19.5
(-3)
A 		138.2
(-1.9)
A 		119.7
(-2.1)
A 		362.8
(0.2)
P 		317.5
(-0.2)
P 		657.8
(3)
P 		638
avr 36.4
(-3) 		84.6
(-2.6) 		148.6
(-2) 		320.1
(-0.5) 		414.8
(0.4) 		709.4
(3) 		673
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 111
1 2 3 4 range
A 7.3
(-3)
A 		37.8
(-1.3)
A 		79.2
(1)
A 		114.2
(3)
P 		107
B 11.8
(-2.9)
A 		9.8
(-3)
A 		55.5
(-0.5)
A 		118.5
(3)
P 		109
C 10
(-3)
A 		36.5
(-1.3)
A 		67.3
(0.8)
A 		101.1
(3)
P 		91
avr 9.7
(-3) 		28
(-1.9) 		67.3
(0.4) 		111.3
(3) 		102

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 279
1 2 3 4 5 6 range
A 13.1
(-3)
A 		14.1
(-3)
A 		35.9
(-2.1)
A 		77.1
(-0.6)
P 		148.3
(2.1)
P 		171.6
(3)
P 		159
B 6.5
(-3)
A 		25.3
(-2.6)
A 		39.2
(-2.3)
A 		77.8
(-1.5)
P 		177
(0.7)
P 		285.5
(3)
P 		279
C 7.2
(-3)
A 		42.2
(-2)
A 		30.5
(-2.3)
A 		73
(-1.1)
P 		102.7
(-0.3)
P 		220.2
(3)
P 		213
avr 8.9
(-3) 		27.2
(-2.5) 		35.2
(-2.3) 		76
(-1.1) 		142.7
(0.7) 		225.8
(3) 		217
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 194079_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.7641
Sequence Type Exemplar sequence
Representative Public ID Y39A1A.11 NCBI
Target Description Y39A1A.11 /REP_DB=WormBase Gene ID /WP=CE19130 /TR=Q9XX28 /GB=CAA21012.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=Alcohol-other dehydrogenases, short chain type, Short chain dehydrogenase-reductase C-terminus
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066945(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066945 NCBI Caenorhabditis elegans DeHydrogenases, Short chain family member (dhs-11) (dhs-11) mRNA, complete cds. 11/11 None
SNAP00000012913 ENSEMBL cdna:SNAP chromosome:CEL140:III:10640763:10657285:-1 11/11 None
GENEFINDER00000012936 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10640763:10642943:-1 11/11 None
Y39A1A.11 ENSEMBL cdna:known chromosome:CEL140:III:10640763:10642949:-1 gene:Y39A1A.11 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10640758-10642945(-) 100.0 100.0
Public Domain and Genome References
Gene Title Alcohol/other dehydrogenases, short chain type, Short chain dehydrogenase/reductase C-terminus
Gene Symbol dhs-11
Ensembl Y39A1A.11
Entrez Gene 176485 Entrez gene
SwissProt Q9XX28 EMBL-EBI
WormBase CE19130 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:265026_AT 3-oxoacyl-(acyl-carrier protein) reductase, chloroplast / 3-ketoacyl-acyl carrier protein reductase at
ATGENOME1:20709_S_AT 3-oxoacyl-(acyl-carrier protein) reductase, chloroplast / 3-ketoacyl-acyl carrier protein reductase at
CANINE_2:CFA.17185.1.S1_AT similar to Estradiol 17-beta-dehydrogenase 8 (17-beta-HSD 8) (17-beta-hydroxysteroid dehydrogenase 8) (Protein Ke6) (Ke-6) cfa
CANINE_2:CFA.17185.1.S1_S_AT similar to Estradiol 17-beta-dehydrogenase 8 (17-beta-HSD 8) (17-beta-hydroxysteroid dehydrogenase 8) (Protein Ke6) (Ke-6) cfa
CANINE_2:CFA.7274.1.A1_AT similar to Estradiol 17-beta-dehydrogenase 8 (17-beta-HSD 8) (17-beta-hydroxysteroid dehydrogenase 8) (Protein Ke6) (Ke-6) cfa
DROSOPHILA_2:1639654_AT dm
DROSGENOME1:144428_AT dm
HG-U95AV2:41440_AT hydroxysteroid (17-beta) dehydrogenase 8 hs
HU35KSUBA:D82061_AT hydroxysteroid (17-beta) dehydrogenase 8 hs
HUGENEFL:D82061_AT hydroxysteroid (17-beta) dehydrogenase 8 hs
U133_X3P:HS.288354.0.S1_3P_AT hydroxysteroid (17-beta) dehydrogenase 8 hs
HG-U133A_2:213540_AT hydroxysteroid (17-beta) dehydrogenase 8 hs
HG-U133_PLUS_2:213540_AT hydroxysteroid (17-beta) dehydrogenase 8 hs
HG-U133A:213540_AT hydroxysteroid (17-beta) dehydrogenase 8 hs
HU35KSUBB:RC_AA113291_AT Hydroxysteroid (17-beta) dehydrogenase 8 hs
MU11KSUBA:U34072-2_S_AT H2-K region expressed gene 6 mm
MG-U74AV2:102992_AT H2-K region expressed gene 6 mm
MG-U74AV2:102991_S_AT H2-K region expressed gene 6 mm
MOE430A:1454987_A_AT H2-K region expressed gene 6 mm
MOUSE430A_2:1454987_A_AT H2-K region expressed gene 6 mm
MOUSE430_2:1454987_A_AT H2-K region expressed gene 6 mm
MU19KSUBC:TC39287_S_AT H2-K region expressed gene 6 (H2-Ke6), mRNA mm
MU19KSUBC:TC39288_S_AT H2-K region expressed gene 6 (H2-Ke6), mRNA mm
RG-U34A:RC_AA866404_AT hydroxysteroid (17-beta) dehydrogenase 8 rn
RAE230A:1382492_A_AT hydroxysteroid (17-beta) dehydrogenase 8 rn
RAT230_2:1382492_A_AT hydroxysteroid (17-beta) dehydrogenase 8 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
16491 oxidoreductase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA21012 Hypothetical protein Y39A1A.11 [Caenorhabditis elegans] ref|NP_499346.1| DeHydrogenases, Short chain family member (dhs-11) [Caenorhabditis elegans] 1.0E-155
blast CAA21012 Hypothetical protein Y39A1A.11 [Caenorhabditis elegans] ref|NP_499346.1| DeHydrogenases, Short chain family member (dhs-11) [Caenorhabditis elegans] 1.0E-142
blast CAA21012 Hypothetical protein Y39A1A.11 [Caenorhabditis elegans] ref|NP_499346.1| DeHydrogenases, Short chain family member (dhs-11) [Caenorhabditis elegans] 1.0E-117
blast CAE71423 Hypothetical protein CBG18334 [Caenorhabditis briggsae] 1.0E-100
blast CAE71423 Hypothetical protein CBG18334 [Caenorhabditis briggsae] 6.0E-96
blast CAE71423 Hypothetical protein CBG18334 [Caenorhabditis briggsae] 3.0E-95
blast AAB52488 Dehydrogenases, short chain protein 25 [Caenorhabditis elegans] ref|NP_508282.2| DeHydrogenases, Short chain family member (dhs-25) [Caenorhabditis elegans] 5.0E-73
Protein Domains
Database ID Description E-Value
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 4.5E-72
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 1.2E-65
Pfam IPR002198 EMBL-EBI Short-chain dehydrogenase/reductase SDR 1.2E-66
Sequence
Target Sequence 
>C. ELEGANS:194079_AT
gaagccacagcaggcaatcttcctggaaatgggcattcggcctttgagattgatgtcagc
gatccagaacacgtggctcgtctacaagaattcataaaatcttccggagaatcgccatct
gtgctcgtgaattgtgcaggcatcaccaaggacgctaccctgttgaaaatgagccagaat
cagtggcaggatgtgatgaatgtcaatttgaatagtgtttttctgatgtctcagatgatt
gctcgtgaatctgtggccgccggatctccgctctccattgtaaacgtgtcgtcgatcgtc
ggaaaaatcggaaatttcggccaaactaactacgctgccactaaatctggagtgattggt
tttacgaaatcggcagccagggagcttgccacaaagaacatccgcgtgaatgctgtgctc
cccggcttcatcagaacaccaatgacagaggctatgcctccgaaggtccttgatgcaatg
gtctcgatggttccacaacggagactcggtgagactgaggagatcgcgaacgccgtgttg
tt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAGCCACAGCAGGCAATCTTCCTG 141 345 292 Antisense
CGCCATCTGTGCTCGTGAATTGTGC 629 257 404 Antisense
TCACCAAGGACGCTACCCTGTTGAA 285 611 434 Antisense
TGATTGCTCGTGAATCTGTGGCCGC 113 565 527 Antisense
CTCCGCTCTCCATTGTAAACGTGTC 271 235 557 Antisense
GTAAACGTGTCGTCGATCGTCGGAA 322 459 571 Antisense
TCGGCCAAACTAACTACGCTGCCAC 577 607 608 Antisense
AGAACATCCGCGTGAATGCTGTGCT 499 73 686 Antisense
TATGCCTCCGAAGGTCCTTGATGCA 564 657 744 Antisense
ATGGTCTCGATGGTTCCACAACGGA 547 49 769 Antisense
AGGAGATCGCGAACGCCGTGTTGTT 360 55 809 Antisense
Sequence Source Affymetrix Proprietary Database