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[194040_at] mouse CREB-binding protein; human transcriptional adaptor protein p300

Description F22F1.3 /REP_DB=WormBase Gene ID /WP=CE04445 /TR=Q19744 /GB=AAA83283.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=mouse CREB-binding protein; human transcriptional adaptor protein p300
Cluster 6grp_total > 34      4grp_total > 22      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 230
1 2 3 4 range
A 240.6
(0.9)
P 		118.6
(-2.3)
A 		93
(-3)
A 		320.8
(3)
P 		228
B 279.9
(3)
P 		109.3
(-3)
A 		125.9
(-2.4)
A 		246.9
(1.8)
P 		171
C 286.2
(2.3)
P 		134.1
(-1.8)
A 		90.5
(-3)
A 		314.1
(3)
P 		224
avr 268.9
(2.2) 		120.7
(-2.4) 		103.1
(-3) 		293.9
(3) 		191

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 112
1 2 3 4 5 6 range
A 177.8
(3)
P 		140.3
(0.8)
A 		151.2
(1.4)
A 		77.4
(-3)
A 		96
(-1.9)
A 		79.2
(-2.9)
A 		100
B 188.3
(2.9)
P 		138.8
(-0.1)
M 		189.6
(3)
P 		90.3
(-3)
A 		91.5
(-2.9)
A 		100.2
(-2.4)
P 		99
C 146.8
(2)
P 		160
(3)
A 		140.1
(1.5)
A 		82.9
(-3)
A 		100
(-1.7)
A 		114.8
(-0.5)
M 		77
avr 171
(3) 		146.4
(1.3) 		160.3
(2.3) 		83.5
(-3) 		95.8
(-2.2) 		98.1
(-2) 		88
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 70
1 2 3 4 range
A 87.6
(3)
P 		25.7
(-2.9)
A 		24.3
(-3)
A 		47
(-0.8)
P 		63
B 89.3
(3)
P 		27
(-3)
A 		29.2
(-2.8)
A 		52.6
(-0.5)
P 		62
C 94.7
(3)
P 		38.6
(-2.3)
A 		31.5
(-3)
A 		53
(-1)
P 		63
avr 90.5
(3) 		30.4
(-2.8) 		28.3
(-3) 		50.9
(-0.8) 		62

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 49
1 2 3 4 5 6 range
A 32.8
(-0.4)
P 		49.9
(3)
A 		32.9
(-0.3)
A 		19.6
(-2.9)
A 		29
(-1.1)
A 		19.3
(-3)
A 		31
B 65.5
(3)
P 		46.2
(0.2)
M 		46
(0.2)
P 		23.9
(-3)
A 		37.2
(-1.1)
A 		37.4
(-1.1)
P 		42
C 54.4
(3)
P 		48.8
(2.1)
A 		35.7
(0)
A 		16.7
(-3)
A 		32.4
(-0.5)
A 		38.4
(0.5)
M 		38
avr 50.9
(3) 		48.3
(2.5) 		38.2
(0.5) 		20.1
(-3) 		32.9
(-0.5) 		31.7
(-0.7) 		31
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 194040_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17164
Sequence Type Exemplar sequence
Representative Public ID F22F1.3 NCBI
Target Description F22F1.3 /REP_DB=WormBase Gene ID /WP=CE04445 /TR=Q19744 /GB=AAA83283.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=mouse CREB-binding protein; human transcriptional adaptor protein p300
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076975(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076975 NCBI Caenorhabditis elegans F22F1.3 (F22F1.3) mRNA, complete cds. 11/11 None
SNAP00000034835 ENSEMBL cdna:SNAP chromosome:CEL140:X:8161784:8163008:-1 11/11 None
GENEFINDER00000034839 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:8161784:8163013:-1 11/11 None
F22F1.3 ENSEMBL cdna:known chromosome:CEL140:X:8161784:8163222:-1 gene:F22F1.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:8161782-8163221(-) 100.0 100.0
Public Domain and Genome References
Gene Title mouse CREB-binding protein; human transcriptional adaptor protein p300
Ensembl F22F1.3
Entrez Gene 184851 Entrez gene
SwissProt Q19744 EMBL-EBI
WormBase CE04445 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6355 regulation of transcription, DNA-dependent inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3712 transcription cofactor activity inferred from electronic annotation QuickGO AmiGO
5515 protein binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA83283 Hypothetical protein F22F1.3 [Caenorhabditis elegans] ref|NP_509376.1| F22F1.3 [Caenorhabditis elegans] 1.0E-155
blast AAA83283 Hypothetical protein F22F1.3 [Caenorhabditis elegans] ref|NP_509376.1| F22F1.3 [Caenorhabditis elegans] 1.0E-140
blast AAA83283 Hypothetical protein F22F1.3 [Caenorhabditis elegans] ref|NP_509376.1| F22F1.3 [Caenorhabditis elegans] 1.0E-139
blast CAE74852 Hypothetical protein CBG22702 [Caenorhabditis briggsae] 5.0E-51
blast CAE74852 Hypothetical protein CBG22702 [Caenorhabditis briggsae] 6.0E-51
blast CAE65110 Hypothetical protein CBG09974 [Caenorhabditis briggsae] 6.0E-14
blast CAE65110 Hypothetical protein CBG09974 [Caenorhabditis briggsae] 8.0E-14
Protein Domains
Database ID Description E-Value
Pfam IPR003101 EMBL-EBI Coactivator CBP, KIX 1.3E-42
Pfam IPR003101 EMBL-EBI Coactivator CBP, KIX 4.3E-44
Pfam IPR003101 EMBL-EBI Coactivator CBP, KIX 1.3E-42
Pfam IPR003101 EMBL-EBI Coactivator CBP, KIX 4.3E-44
Pfam IPR003101 EMBL-EBI Coactivator CBP, KIX 1.3E-42
Pfam IPR003101 EMBL-EBI Coactivator CBP, KIX 4.3E-44
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509376.1 1 12-34
F22F1.3 1 12-34
Sequence
Target Sequence 
>C. ELEGANS:194040_AT
gaatactacgccgaacttgccagaattatacttagcatgcagaaacacttgcagtcaagg
cccaaaggatcttatgaagatccgtactcgaatattcctccatcccacgagctggctgat
tttttggggttgtcggcacaagaaagggacgagttttatcttttgcatccacatagacta
ttaaaaccaaatgcaaagtcgagaataacaagaagaattcgaattcatgtgatcgacaaa
ctcgggctcatgctcttccctgccccagatcaaaatgcgtattacgatggaagaatggat
agaatcattagaaaattgcggaatcttgaagctgaagcatttcgagaatgtattgattgt
gatgattattacaacttggcttctatcaaagcttacaaattgcataaaacaatgaagaaa
aatggagagcattatgttgaccacgaggtcaaatacccagccattcacatttatacat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAATACTACGCCGAACTTGCCAGAA 201 327 367 Antisense
GAAACACTTGCAGTCAAGGCCCAAA 607 355 408 Antisense
AAGATCCGTACTCGAATATTCCTCC 431 155 443 Antisense
CATCCCACGAGCTGGCTGATTTTTT 602 211 467 Antisense
GCTGATTTTTTGGGGTTGTCGGCAC 629 293 481 Antisense
GACGAGTTTTATCTTTTGCATCCAC 500 379 514 Antisense
TCCCTGCCCCAGATCAAAATGCGTA 415 597 623 Antisense
GATTATTACAACTTGGCTTCTATCA 198 429 730 Antisense
GAGAGCATTATGTTGACCACGAGGT 110 395 791 Antisense
GACCACGAGGTCAAATACCCAGCCA 5 385 805 Antisense
TACCCAGCCATTCACATTTATACAT 611 649 820 Antisense
Sequence Source Affymetrix Proprietary Database