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[194020_s_at] tyrosine-protein kinase (KIN15/KIN16 subfamily) (2 domains)

Description M176.7 /REP_DB=WormBase Gene ID /WP=CE12472 /GEN=kin-16 /TR=SW:P34892 /GB=CAB01652.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase (KIN15-KIN16 subfamily) (2 domains)
Cluster 6grp_highest_10_10 > 35      6grp_high1_10_10 > 53      4grp_highest_8_8 > 52      4grp_high_8_8 > 17      6grp_highest_nonorm > 62      6grp_total > 53      4grp_total > 31      6grp_highest_sub > 03      6grp_cgc > 82      6grp_high1_sub > 03      6grp_cgc_sub > 03      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 297
1 2 3 4 range
A 662.2
(3)
P 		430.1
(-3)
P 		454.5
(-2.4)
P 		559.5
(0.3)
P 		232
B 608.7
(3)
P 		477.4
(-0.3)
P 		369.7
(-3)
P 		477.1
(-0.3)
P 		239
C 666.3
(3)
P 		450.7
(-3)
P 		467.2
(-2.5)
P 		579.1
(0.6)
P 		216
avr 645.7
(3) 		452.7
(-2.4) 		430.5
(-3) 		538.6
(0) 		215

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 435
1 2 3 4 5 6 range
A 398.6
(-2.6)
P 		559.6
(0.1)
P 		730.6
(3)
P 		487.8
(-1.1)
P 		375.8
(-3)
P 		442.4
(-1.9)
P 		355
B 438
(-2.1)
P 		581.7
(3)
P 		556
(2.1)
P 		472.2
(-0.9)
P 		420.2
(-2.7)
P 		412.8
(-3)
P 		169
C 378.2
(-1.7)
P 		547.4
(1)
P 		673.9
(3)
P 		540.9
(0.9)
P 		296
(-3)
P 		497.9
(0.2)
P 		378
avr 404.9
(-2.2) 		562.9
(1.1) 		653.5
(3) 		500.3
(-0.2) 		364
(-3) 		451
(-1.2) 		290
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 159
1 2 3 4 range
A 241.1
(3)
P 		93.4
(-2.6)
P 		118.8
(-1.6)
P 		81.9
(-3)
P 		159
B 194.1
(3)
P 		117.9
(-1.2)
P 		85.7
(-3)
P 		101.7
(-2.1)
P 		108
C 220.6
(3)
P 		129.6
(-1.4)
P 		162.8
(0.2)
P 		97.6
(-3)
P 		123
avr 218.6
(3) 		113.6
(-2) 		122.4
(-1.6) 		93.7
(-3) 		125

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 126
1 2 3 4 5 6 range
A 73.5
(-3)
P 		199
(3)
P 		159.1
(1.1)
P 		123.7
(-0.6)
P 		113.4
(-1.1)
P 		107.7
(-1.4)
P 		126
B 152.4
(-0.6)
P 		193.6
(3)
P 		135
(-2.1)
P 		125.1
(-3)
P 		170.7
(1)
P 		153.9
(-0.5)
P 		69
C 140.2
(0.5)
P 		167
(2.6)
P 		171.5
(3)
P 		108.8
(-2)
P 		95.8
(-3)
P 		166.7
(2.6)
P 		76
avr 122
(-2.8) 		186.5
(3) 		155.2
(0.2) 		119.2
(-3) 		126.6
(-2.3) 		142.8
(-0.9) 		67
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 194020_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3172
Sequence Type Exemplar sequence
Representative Public ID M176.7 NCBI
Target Description M176.7 /REP_DB=WormBase Gene ID /WP=CE12472 /GEN=kin-16 /TR=SW:P34892 /GB=CAB01652.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=tyrosine-protein kinase (KIN15-KIN16 subfamily) (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063616(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063616 NCBI Caenorhabditis elegans protein KINase family member (kin-16) (kin-16) mRNA, complete cds. 11/11 None
SNAP00000025006 ENSEMBL cdna:SNAP chromosome:CEL140:II:9434064:9435972:-1 11/11 None
GENEFINDER00000025015 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:9434064:9438006:-1 11/11 None
M176.7 ENSEMBL cdna:known chromosome:CEL140:II:9433998:9436019:-1 gene:M176.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:9434060-9435969(-) 100.0 100.0
Public Domain and Genome References
Gene Title tyrosine-protein kinase (KIN15/KIN16 subfamily) (2 domains)
Gene Symbol kin-16
Ensembl M176.7
Entrez Gene 174499 Entrez gene
SwissProt P34892 EMBL-EBI
WormBase CE12472 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01652 Hypothetical protein M176.7 [Caenorhabditis elegans] ref|NP_496017.1| protein KINase family member (kin-16) [Caenorhabditis elegans] sp|P34892|KIN16_CAEEL Receptor-like tyrosine-protein kinase kin-16 precursor gb|AAA28152.1| protein-tyrosine kinase 0.0
blast CAB01653 Hypothetical protein M176.8 [Caenorhabditis elegans] ref|NP_496018.1| M176.8 [Caenorhabditis elegans] 0.0
blast CAE67807 Hypothetical protein CBG13385 [Caenorhabditis briggsae] 1.0E-152
blast CAA91990 Hypothetical protein F59F3.1 [Caenorhabditis elegans] ref|NP_509836.1| VEGF (vascular endothelial growth factor) Receptor family member (ver-3) [Caenorhabditis elegans] 1.0E-111
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.5E-63
Pfam IPR000719 EMBL-EBI Protein kinase 1.5E-63
Pfam IPR001223 EMBL-EBI Glycoside hydrolase, family 18 1.4E-29
Pfam IPR001223 EMBL-EBI Glycoside hydrolase, family 18 9.2E-63
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_496017.1 1 61-83
M176.7 1 61-83
SNAP00000025006 1 61-83
GENEFINDER00000025015 3 21-43,392-409,455-477
Sequence
Target Sequence 
>C. ELEGANS:194020_S_AT
tgacaacatctgatcttctttcctttggacttcaaatagctaacggaatgcaatacttgg
cttctattccgatggttcacagagatttggcgctaagaaatgtgctcctaaaaaagaaca
aaacaattcgaatcgcagattttggaatggcaagaacacatgaaaacaagtcatactata
taccacaaaaaaccaaagatgctccggtaccagttcgctggatgtctccagaagctttcg
acacaatgaagtttaccgaaaaatctgatgtctggtcatttggtatctgcctctatgaga
tcttcacgctgggacaacttccatatccagatgtgccatcagaacgaatttatgaatata
tgcatagcggtagacgatgtcctcaaccacagcattgccatgttgaattatatgatctta
tgaaactttgctggcatgagaaacccgagctacggcctaacttctctaattgcgtcgaat
acttcatcgggcaca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGACAACATCTGATCTTCTTTCCTT 17 573 890 Antisense
CTTGGCTTCTATTCCGATGGTTCAC 113 217 945 Antisense
GGTACCAGTTCGCTGGATGTCTCCA 344 505 1095 Antisense
GGTCATTTGGTATCTGCCTCTATGA 669 503 1163 Antisense
AGATCTTCACGCTGGGACAACTTCC 535 61 1187 Antisense
AACTTCCATATCCAGATGTGCCATC 404 139 1205 Antisense
TAGCGGTAGACGATGTCCTCAACCA 387 651 1254 Antisense
TCCTCAACCACAGCATTGCCATGTT 535 591 1269 Antisense
TGGCATGAGAAACCCGAGCTACGGC 310 543 1321 Antisense
GCTACGGCCTAACTTCTCTAATTGC 612 295 1338 Antisense
TGCGTCGAATACTTCATCGGGCACA 102 583 1360 Antisense
Sequence Source Affymetrix Proprietary Database