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[193988_at] similarity with a human hypothetical protein (PIR Acc. No. A38919)

Description D2085.4 /REP_DB=WormBase Gene ID /WP=CE15744 /TR=O17736 /GB=CAA91061.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=similarity with a human hypothetical protein (PIR Acc. No. A38919)
Cluster 6grp_highest_10_10 > 64      6grp_high1_10_10 > 46      4grp_highest_8_8 > 52      4grp_high_8_8 > 16      6grp_highest_nonorm > 74      6grp_total > 47      4grp_total > 39      6grp_highest_sub > Cu      6grp_high1_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 368
1 2 3 4 range
A 825.6
(3)
P 		538.7
(-2.1)
P 		487.5
(-3)
P 		512.1
(-2.6)
P 		338
B 789.9
(3)
P 		498.3
(-2.6)
P 		477.4
(-3)
P 		700.9
(1.3)
P 		313
C 828.4
(3)
P 		460.3
(-3)
P 		541.2
(-1.7)
P 		633
(-0.2)
P 		368
avr 814.6
(3) 		499.1
(-3) 		502
(-2.9) 		615.3
(-0.8) 		316

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 371
1 2 3 4 5 6 range
A 722.1
(-0.5)
P 		825
(1.1)
P 		704.7
(-0.8)
P 		939.7
(3)
P 		568.7
(-3)
P 		870.5
(1.9)
P 		371
B 816.8
(3)
P 		719.2
(0.4)
P 		613
(-2.4)
P 		650.8
(-1.4)
P 		590
(-3)
P 		732.3
(0.8)
P 		227
C 878.3
(3)
P 		718.9
(-3)
P 		876.4
(2.9)
P 		773
(-1)
P 		720.3
(-2.9)
P 		863
(2.4)
P 		159
avr 805.7
(2.5) 		754.4
(0.9) 		731.4
(0.2) 		787.8
(2) 		626.3
(-3) 		821.9
(3) 		196
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 226
1 2 3 4 range
A 300.6
(3)
P 		116.9
(-1.9)
P 		127.5
(-1.6)
P 		75
(-3)
P 		226
B 251.9
(3)
P 		123.1
(-2.5)
P 		110.6
(-3)
P 		149.4
(-1.4)
P 		141
C 274.2
(3)
P 		132.3
(-2.1)
P 		188.6
(-0.1)
P 		106.7
(-3)
P 		168
avr 275.6
(3) 		124.1
(-2.5) 		142.2
(-1.8) 		110.4
(-3) 		165

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 193
1 2 3 4 5 6 range
A 133.1
(-3)
P 		293.4
(3)
P 		153.5
(-2.2)
P 		238.3
(0.9)
P 		171.6
(-1.6)
P 		212
(-0)
P 		160
B 284.2
(3)
P 		239.4
(1)
P 		148.8
(-3)
P 		172.4
(-2)
P 		239.7
(1)
P 		273.1
(2.5)
P 		135
C 325.6
(3)
P 		219.4
(-0.7)
P 		223
(-0.6)
P 		155.5
(-3)
P 		233.1
(-0.3)
P 		288.9
(1.7)
P 		170
avr 247.6
(2.2) 		250.7
(2.5) 		175.1
(-3) 		188.7
(-2) 		214.8
(-0.1) 		258
(3) 		83
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193988_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2848
Sequence Type Exemplar sequence
Representative Public ID D2085.4 NCBI
Target Description D2085.4 /REP_DB=WormBase Gene ID /WP=CE15744 /TR=O17736 /GB=CAA91061.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=similarity with a human hypothetical protein (PIR Acc. No. A38919)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063441(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063441 NCBI Caenorhabditis elegans D2085.4 (D2085.4) mRNA, complete cds. 11/11 None
SNAP00000003895 ENSEMBL cdna:SNAP chromosome:CEL140:II:8667419:8668987:1 11/11 None
GENEFINDER00000003896 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8664756:8668987:1 11/11 None
D2085.4 ENSEMBL cdna:known chromosome:CEL140:II:8664795:8669058:1 gene:D2085.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8664812-8668984(+) 100.0 100.0
Public Domain and Genome References
Gene Title similarity with a human hypothetical protein (PIR Acc. No. A38919)
Ensembl D2085.4
Entrez Gene 174388 Entrez gene
SwissProt O17736 EMBL-EBI
WormBase CE15744 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6464 protein modification inferred from electronic annotation QuickGO AmiGO
6512 ubiquitin cycle inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5622 intracellular inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4842 ubiquitin-protein ligase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91061 Hypothetical protein D2085.4 [Caenorhabditis elegans] ref|NP_495842.1| D2085.4 [Caenorhabditis elegans] 0.0
blast CAE57534 Hypothetical protein CBG00511 [Caenorhabditis briggsae] 0.0
blast CAE57534 Hypothetical protein CBG00511 [Caenorhabditis briggsae] 1.0E-149
blast XP_396547 PREDICTED: similar to ENSANGP00000004863 [Apis mellifera] 3.0E-91
Protein Domains
Database ID Description E-Value
Pfam IPR000569 EMBL-EBI HECT domain (Ubiquitin-protein ligase) 1.4E-50
Pfam IPR000569 EMBL-EBI HECT domain (Ubiquitin-protein ligase) 1.4E-50
Pfam IPR000569 EMBL-EBI HECT domain (Ubiquitin-protein ligase) 1.4E-50
Sequence
Target Sequence 
>C. ELEGANS:193988_AT
ggacgaactacagctagacttcagtgtggtcacaagtgacatgggattggttagaaatgt
gaacctgaaaccaaacggatcgaaatttcgggttactgtagagaatgtgcacgaatatgt
tcgtctctacgtcaattatcatttgaaacaaaggatcgcctcaatggttgacgccgttcg
gaaaggaatcagtgagatcatcagtattgaatggatgagaatgtttgcaccacatgagct
tcaaattatgatagctggatacgaagaagttttcacagcgaaagagctcagaaagttctg
cgaacttcgtttcgctgctggaacacaagacataaattacgaagaaatgttctgggatgt
tatcgataaactatccaatgatgataagaaggcacttttgaaatttgttaccggttgttc
tcgagctccagttgatggcttcaaaagtattcaaccacgaatgggtgttttagtgattcc
atcctccgacgacgagttgccaacaagtgccacatgtatgaatatgctcagaattccgaa
atattcaaatcgcacaaagctggaagagaagcttcgctacgccata

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGACGAACTACAGCTAGACTTCAGT 29 525 2403 Antisense
TATGTTCGTCTCTACGTCAATTATC 513 653 2518 Antisense
AAGGATCGCCTCAATGGTTGACGCC 4 161 2553 Antisense
GACGCCGTTCGGAAAGGAATCAGTG 602 379 2572 Antisense
GAATGTTTGCACCACATGAGCTTCA 413 331 2621 Antisense
GTTCTGCGAACTTCGTTTCGCTGCT 533 443 2697 Antisense
GTTTCGCTGCTGGAACACAAGACAT 194 449 2711 Antisense
ATTTGTTACCGGTTGTTCTCGAGCT 154 13 2805 Antisense
GGGTGTTTTAGTGATTCCATCCTCC 377 497 2865 Antisense
ACGAGTTGCCAACAAGTGCCACATG 432 93 2894 Antisense
GGAAGAGAAGCTTCGCTACGCCATA 548 531 2964 Antisense
Sequence Source Affymetrix Proprietary Database