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[193982_at] CTP SYNTHASE (EC 6.3.4.2) (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)

Description W06H3.3 /REP_DB=WormBase Gene ID /WP=CE19014 /TR=Q9XXN1 /GB=CAA16517.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=CTP SYNTHASE (EC 6.3.4.2) (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
Cluster 6grp_total > 40      4grp_total > 21      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 81
1 2 3 4 range
A 65.4
(2.8)
A
22.8
(-3)
A
46.7
(0.3)
A
66.9
(3)
A
44
B 11.6
(-2.1)
A
23.3
(-0.5)
A
4.9
(-3)
A
49.3
(3)
A
44
C 69.4
(1.7)
A
57.5
(0.8)
A
8.9
(-3)
A
85.9
(3)
A
77
avr 48.8
(0.6)
34.5
(-1.2)
20.2
(-3)
67.4
(3)
47

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 67
1 2 3 4 5 6 range
A 28.3
(-1)
A
53.4
(1.5)
A
47.4
(0.9)
A
68.2
(3)
A
8.8
(-3)
A
38.7
(0)
A
59
B 9.7
(-2.9)
A
40.9
(-0)
A
73.4
(3)
A
20.7
(-1.9)
A
48.2
(0.7)
A
8.9
(-3)
A
65
C 62.9
(3)
A
37
(0.3)
A
6
(-3)
A
59.3
(2.6)
A
9.2
(-2.7)
A
16.6
(-1.9)
A
57
avr 33.6
(-0.4)
43.8
(1.8)
42.3
(1.5)
49.4
(3)
22.1
(-2.9)
21.4
(-3)
28
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 23
1 2 3 4 range
A 23.8
(3)
A
4.9
(-3)
A
12.2
(-0.7)
A
9.8
(-1.4)
A
19
B 3.7
(-1.3)
A
5.8
(-0)
A
1.1
(-3)
A
10.5
(3)
A
9
C 23
(3)
A
16.5
(1)
A
3.1
(-3)
A
14.5
(0.4)
A
20
avr 16.8
(3)
9.1
(-1.1)
5.5
(-3)
11.6
(0.2)
11

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 22
1 2 3 4 5 6 range
A 5.2
(-2.1)
A
19
(3)
A
10.3
(-0.2)
A
17.3
(2.4)
A
2.7
(-3)
A
9.4
(-0.5)
A
16
B 3.4
(-3)
A
13.6
(0.8)
A
17.8
(2.3)
A
5.5
(-2.2)
A
19.6
(3)
A
3.3
(-3)
A
16
C 23.3
(3)
A
11.3
(-0.3)
A
1.5
(-3)
A
11.9
(-0.1)
A
3
(-2.6)
A
5.5
(-1.9)
A
22
avr 10.6
(0.2)
14.6
(3)
9.9
(-0.3)
11.6
(0.9)
8.4
(-1.4)
6.1
(-3)
9
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193982_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14727
Sequence Type Exemplar sequence
Representative Public ID W06H3.3 NCBI
Target Description W06H3.3 /REP_DB=WormBase Gene ID /WP=CE19014 /TR=Q9XXN1 /GB=CAA16517.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=CTP SYNTHASE (EC 6.3.4.2) (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074842(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_074842 NCBI Caenorhabditis elegans W06H3.3 (W06H3.3) mRNA, complete cds. 11/11 None
SNAP00000017340 ENSEMBL cdna:SNAP chromosome:CEL140:V:16797914:16802737:1 11/11 None
GENEFINDER00000017345 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:16797914:16802737:1 11/11 None
W06H3.3 ENSEMBL cdna:known chromosome:CEL140:V:16797914:16804393:1 gene:W06H3.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:16797913-16802811(+) 100.0 100.0
Public Domain and Genome References
Gene Title CTP SYNTHASE (EC 6.3.4.2) (UTP--AMMONIA LIGASE) (CTP SYNTHETASE)
Ensembl W06H3.3
Entrez Gene 189267 Entrez gene
SwissProt Q9XXN1 EMBL-EBI
WormBase CE29830 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:257702_AT CTP synthase, putative / UTP--ammonia ligase, putative at
CANINE:1585851_AT similar to cytidine triphosphate synthase II cfa
CANINE_2:CFA.10572.1.A1_AT similar to cytidine triphosphate synthase II cfa
CANINE_2:CFAAFFX.19379.1.S1_S_AT similar to cytidine triphosphate synthase II cfa
CANINE_2:CFAAFFX.19388.1.S1_AT similar to cytidine triphosphate synthase II cfa
CANINE_2:CFAAFFX.19511.1.S1_AT similar to cytidine triphosphate synthase II cfa
CHICKEN:GGA.16217.1.S1_S_AT CTP synthase II gga
CHICKEN:GGAAFFX.10590.1.S1_AT CTP synthase II gga
HG-U133_PLUS_2:222819_AT CTP synthase II hs
HG-U133B:222819_AT CTP synthase II hs
HG-U133_PLUS_2:219080_S_AT CTP synthase II hs
HG-U133A:219080_S_AT CTP synthase II hs
HG-FOCUS:219080_S_AT CTP synthase II hs
HG-U133A_2:219080_S_AT CTP synthase II hs
HU35KSUBA:AA121287_AT CTP synthase II hs
HU35KSUBA:RC_AA233949_AT CTP synthase II hs
HU35KSUBC:RC_AA251012_AT CTP synthase II hs
U133_X3P:G9789918_3P_S_AT CTP synthase II hs
U133_X3P:HS.58553.0.S2_3P_AT CTP synthase II hs
HG-U95B:45362_G_AT CTP synthase II hs
HG-U95C:62475_AT CTP synthase II hs
HG-U95C:64894_AT CTP synthase II hs
HG-U95B:45361_AT CTP synthase II hs
HG-U95E:72605_AT CTP synthase II hs
MU11KSUBA:U49385_S_AT cytidine 5'-triphosphate synthase 2 mm
MG-U74CV2:137977_S_AT cytidine 5'-triphosphate synthase 2 mm
MG-U74AV2:160652_AT cytidine 5'-triphosphate synthase 2 mm
MOE430A:1435759_AT cytidine 5'-triphosphate synthase 2 mm
MOUSE430A_2:1435759_AT cytidine 5'-triphosphate synthase 2 mm
MOUSE430_2:1435759_AT cytidine 5'-triphosphate synthase 2 mm
MOE430A:1448111_AT cytidine 5'-triphosphate synthase 2 mm
MOUSE430A_2:1448111_AT cytidine 5'-triphosphate synthase 2 mm
MOUSE430_2:1448111_AT cytidine 5'-triphosphate synthase 2 mm
YEAST_2:1779018_AT Minor CTP synthase isozyme (see also URA7), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6221 pyrimidine nucleotide biosynthesis inferred from electronic annotation QuickGO AmiGO
6412 protein biosynthesis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5622 intracellular inferred from electronic annotation QuickGO AmiGO
5840 ribosome inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3735 structural constituent of ribosome inferred from electronic annotation QuickGO AmiGO
3824 catalytic activity inferred from electronic annotation QuickGO AmiGO
3883 CTP synthase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAD21649 Hypothetical protein W06H3.3 [Caenorhabditis elegans] emb|CAA16517.2| Hypothetical protein W06H3.3 [Caenorhabditis elegans] ref|NP_507243.2| W06H3.3 [Caenorhabditis elegans] 0.0
blast CAE56255 Hypothetical protein CBG23896 [Caenorhabditis briggsae] 0.0
blast AAH58048 CTP synthase [Danio rerio] ref|NP_954681.1| CTP synthase [Danio rerio] 1.0E-149
Protein Domains
Database ID Description E-Value
Pfam IPR000991 EMBL-EBI Glutamine amidotransferase class-I 4.1E-33
Pfam IPR004468 EMBL-EBI CTP synthase 1.0E-126
Pfam IPR000991 EMBL-EBI Glutamine amidotransferase class-I 4.1E-33
Pfam IPR004468 EMBL-EBI CTP synthase 4.9E-16
Pfam IPR004468 EMBL-EBI CTP synthase 1.0E-126
Sequence
Target Sequence
>C. ELEGANS:193982_AT
gcaagtggcggctatcgaattcgctagaaatgttctgagcatcgacggagccaattcgac
ggaatttaactcgaaattgcacgaaaatcagcagattgtgatcgatatgccagaacataa
tgttgaagagaagggattgggtggaactatgcgtcttggaagacgttctacagtattcct
taccgacgaatgcattcttcaccgtctctacggaactcacacagtggaagaacgtcaccg
tcaccgttacgaagtgaatccccacgttgttccacaaatggctcggaagggattcttgtt
cgtcggaatgggtgtagatgaacagaatactgatatttgggatgttaagaagcgaaccga
cagctcggcggagcttatgcagatggctgatcagactgaaattgatttgttgcacaaaat
tgatgatttgtgtcagagaggaggcgatggggttactcggccagctgttcgtatggaa


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
GCAAGTGGCGGCTATCGAATTCGCT 278 321 1245 Antisense
GGATTGGGTGGAACTATGCGTCTTG 526 505 1378 Antisense
GACGAATGCATTCTTCACCGTCTCT 442 379 1429 Antisense
ACCGTCTCTACGGAACTCACACAGT 146 89 1445 Antisense
ACAGTGGAAGAACGTCACCGTCACC 496 103 1465 Antisense
TACGAAGTGAATCCCCACGTTGTTC 319 649 1492 Antisense
GGCTCGGAAGGGATTCTTGTTCGTC 362 537 1524 Antisense
AAGAAGCGAACCGACAGCTCGGCGG 694 151 1591 Antisense
GCTCGGCGGAGCTTATGCAGATGGC 551 299 1607 Antisense
GAGGAGGCGATGGGGTTACTCGGCC 658 401 1682 Antisense
TACTCGGCCAGCTGTTCGTATGGAA 353 645 1698 Antisense
Sequence Source Affymetrix Proprietary Database