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[193973_at] Helix-loop-helix DNA-binding domain, serine/threonine kinase

Description Y106G6E.1 /REP_DB=WormBase Gene ID /WP=CE20405 /TR=Q9N667 /GB=CAB76409.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Helix-loop-helix DNA-binding domain, serine-threonine kinase
Cluster 6grp_total > 73      4grp_total > 0      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 77
1 2 3 4 range
A 9.8
(-3)
A 		10.2
(-3)
A 		52.8
(1.5)
A 		67.3
(3)
A 		58
B 18.2
(1.9)
A 		3.4
(-3)
A 		17.1
(1.5)
A 		21.5
(3)
A 		18
C 41.1
(-0.8)
A 		18.9
(-3)
A 		26.8
(-2.2)
A 		80.2
(3)
A 		61
avr 23
(-1.4) 		10.8
(-3) 		32.2
(-0.2) 		56.3
(3) 		46

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 56
1 2 3 4 5 6 range
A 22.9
(-1.3)
A 		7.7
(-3)
A 		7.5
(-3)
A 		45.4
(1.2)
A 		61.7
(3)
A 		29.8
(-0.5)
A 		54
B 23.1
(-3)
A 		38.2
(-0.8)
A 		48.1
(0.7)
M 		63.4
(3)
A 		49.6
(0.9)
A 		27.6
(-2.3)
A 		40
C 41
(1.1)
A 		26
(-0.9)
A 		55.6
(3)
A 		16.9
(-2.1)
A 		9.7
(-3)
A 		38.1
(0.7)
P 		46
avr 29
(-1.3) 		24
(-3) 		37.1
(1.4) 		41.9
(3) 		40.3
(2.5) 		31.8
(-0.4) 		18
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 13
1 2 3 4 range
A 3.6
(-2.3)
A 		2.2
(-3)
A 		13.8
(3)
A 		9.9
(1)
A 		12
B 5.8
(3)
A 		0.8
(-3)
A 		4
(0.8)
A 		4.6
(1.6)
A 		5
C 13.6
(3)
A 		5.4
(-3)
A 		9.3
(-0.1)
A 		13.5
(2.9)
A 		8
avr 7.7
(1.5) 		2.8
(-3) 		9
(2.7) 		9.3
(3) 		7

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 19
1 2 3 4 5 6 range
A 4.2
(-2.1)
A 		2.7
(-2.6)
A 		1.6
(-3)
A 		11.5
(0.5)
A 		18.6
(3)
A 		7.3
(-1)
A 		17
B 8
(-3)
A 		12.7
(-0.7)
A 		11.7
(-1.2)
M 		16.8
(1.3)
A 		20.2
(3)
A 		10.3
(-1.9)
A 		12
C 15.2
(3)
A 		7.9
(-0.6)
A 		14.2
(2.5)
A 		3.4
(-2.9)
A 		3.1
(-3)
A 		12.8
(1.8)
P 		12
avr 9.1
(-1.7) 		7.8
(-3) 		9.2
(-1.6) 		10.6
(-0.3) 		14
(3) 		10.1
(-0.8) 		6
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193973_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.616
Sequence Type Exemplar sequence
Representative Public ID Y106G6E.1 NCBI
Target Description Y106G6E.1 /REP_DB=WormBase Gene ID /WP=CE20405 /TR=Q9N667 /GB=CAB76409.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Helix-loop-helix DNA-binding domain, serine-threonine kinase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060288(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060288 NCBI Caenorhabditis elegans Y106G6E.1 (Y106G6E.1) mRNA, complete cds. 11/11 None
Y106G6E.1 ENSEMBL cdna:known chromosome:CEL140:I:10206407:10208561:-1 gene:Y106G6E.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:10206337-10208492(-) 100.0 100.0
Public Domain and Genome References
Gene Title Helix-loop-helix DNA-binding domain, serine/threonine kinase
Ensembl Y106G6E.1
Entrez Gene 190919 Entrez gene
SwissProt Q9N667 EMBL-EBI
WormBase CE20405 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6468 protein amino acid phosphorylation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4672 protein kinase activity inferred from electronic annotation QuickGO AmiGO
4674 protein serine/threonine kinase activity inferred from electronic annotation QuickGO AmiGO
4713 protein-tyrosine kinase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB76409 Hypothetical protein Y106G6E.1 [Caenorhabditis elegans] emb|CAB76732.1| Hypothetical protein Y106G6E.1 [Caenorhabditis elegans] ref|NP_492689.1| Y106G6E.1 [Caenorhabditis elegans] 0.0
blast CAB02275 Hypothetical protein C36B1.10 [Caenorhabditis elegans] ref|NP_492367.1| C36B1.10 [Caenorhabditis elegans] 1.0E-180
blast CAE60578 Hypothetical protein CBG04212 [Caenorhabditis briggsae] 1.0E-134
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-56
hanks 3.1.7 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; PCTAIRE1 1.0E-52
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 7.9E-59
Sequence
Target Sequence 
>C. ELEGANS:193973_AT
tcatcgtccatccaatctacaaaatcaccacagcaaagttatcatgtcacgagatactac
agaccaccagaattgattttaggctccaagtactatggatgcaaaattgacacgtggtct
tgcggatgtgtatttggagagctactgaaaggcggaatcatcttggctggaaaatcatcg
aacaatcaagcggaggtcattttcgatatgctcggatacccaacagattctgatgtgtca
tcaatgaaagtgagcagcacgaagttgcaggaagttttggattcatatgaatataataaa
tcgaagacaactgccgacttgacttatctctacacacagacagtcatttatcagaaggat
cggagaactacagtctataatacgaaaattgagcaagatgacatgaaagagtcagtagca
gttcttcttcaaatccttgtctacaatccgaacaagcgtctctctggaattgagattctc
actcatccgtactttaatgtgttattcaacgagaaaacggtgagattcaataaaaagaag
attttgtgtctttctgcagtcgacttacaatccgtgaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCATCGTCCATCCAATCTACAAAAT 516 621 532 Antisense
TCACGAGATACTACAGACCACCAGA 165 627 578 Antisense
AATTGACACGTGGTCTTGCGGATGT 265 179 636 Antisense
GAAAGGCGGAATCATCTTGGCTGGA 209 361 678 Antisense
TGCTCGGATACCCAACAGATTCTGA 641 579 740 Antisense
ATCGAAGACAACTGCCGACTTGACT 385 37 831 Antisense
CGACTTGACTTATCTCTACACACAG 85 253 846 Antisense
TACAATCCGAACAAGCGTCTCTCTG 432 641 973 Antisense
ATTCTCACTCATCCGTACTTTAATG 702 9 1006 Antisense
GATTTTGTGTCTTTCTGCAGTCGAC 267 429 1071 Antisense
TGCAGTCGACTTACAATCCGTGAAA 185 579 1086 Antisense
Sequence Source Affymetrix Proprietary Database