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[193971_at]

Description C52A11.4 /REP_DB=WormBase Gene ID /WP=CE24861 /TR=Q09515 /GB=CAA86789.2 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=lethal(1) discs large-1 tumor suppressor protein-like repeats
Cluster 6grp_total > 17      4grp_total > 46      6grp_cgc > 13      6grp_cgc_sub > De      6grp_total_sub > Decrease      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 307
1 2 3 4 range
A 272.8
(3)
P 		147.3
(0)
A 		19.2
(-3)
A 		42.8
(-2.4)
A 		254
B 263.5
(3)
P 		101.2
(-2.9)
A 		104.4
(-2.7)
A 		97.3
(-3)
A 		166
C 326.6
(3)
A 		159.6
(-1.3)
A 		94.6
(-3)
A 		104.7
(-2.7)
A 		232
avr 287.6
(3) 		136
(-1.2) 		72.7
(-3) 		81.6
(-2.8) 		215

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 462
1 2 3 4 5 6 range
A 159.8
(0.5)
A 		265.4
(3)
P 		14.3
(-3)
A 		130.3
(-0.2)
A 		23.7
(-2.8)
A 		109.6
(-0.7)
A 		251
B 179
(3)
A 		151
(2)
A 		17.7
(-3)
A 		74.2
(-0.9)
A 		63.2
(-1.3)
A 		49.1
(-1.8)
A 		161
C 468.1
(3)
P 		51.3
(-2.4)
A 		118.3
(-1.5)
A 		23.6
(-2.8)
A 		109.9
(-1.7)
A 		6.4
(-3)
A 		462
avr 269
(3) 		155.9
(-0.1) 		50.1
(-3) 		76
(-2.3) 		65.6
(-2.6) 		55
(-2.9) 		219
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 103
1 2 3 4 range
A 99.3
(3)
P 		32
(-1.3)
A 		5
(-3)
A 		6.3
(-2.9)
A 		94
B 84
(3)
P 		25
(-2.6)
A 		24.2
(-2.7)
A 		20.7
(-3)
A 		63
C 108.1
(3)
A 		45.9
(-1.1)
A 		33
(-2)
A 		17.7
(-3)
A 		90
avr 97.1
(3) 		34.3
(-1.6) 		20.7
(-2.6) 		14.9
(-3) 		82

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 171
1 2 3 4 5 6 range
A 29.5
(-1.3)
A 		94.4
(3)
P 		3.1
(-3)
A 		33
(-1)
A 		7.2
(-2.7)
A 		26.7
(-1.4)
A 		91
B 62.3
(3)
A 		50.3
(1.8)
A 		4.3
(-3)
A 		19.6
(-1.4)
A 		25.7
(-0.8)
A 		18.3
(-1.6)
A 		58
C 173.5
(3)
P 		15.6
(-2.5)
A 		30.1
(-2)
A 		4.7
(-2.9)
A 		35.6
(-1.8)
A 		2.1
(-3)
A 		171
avr 88.4
(3) 		53.4
(0.2) 		12.5
(-3) 		19.1
(-2.5) 		22.8
(-2.2) 		15.7
(-2.7) 		76
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193971_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3963
Sequence Type Exemplar sequence
Representative Public ID C52A11.4 NCBI
Target Description C52A11.4 /REP_DB=WormBase Gene ID /WP=CE24861 /TR=Q09515 /GB=CAA86789.2 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=lethal(1) discs large-1 tumor suppressor protein-like repeats
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001026867(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001026867 NCBI Caenorhabditis elegans Multiple PDZ domain protein family member (mpz-1) (mpz-1) mRNA, complete cds. 11/11 None
SNAP00000035266 ENSEMBL cdna:SNAP chromosome:CEL140:II:10739186:10742447:-1 11/11 None
GENEFINDER00000035275 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:10739186:10742447:-1 11/11 None
C52A11.4a ENSEMBL cdna:known chromosome:CEL140:II:10738558:10766552:-1 gene:C52A11.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Splice Variants
Entrez Total Refseq Isoforms Total Detected By This Probeset Refseq Probesets
174657 2 1 NM_001026867 193971_at (11)
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:10739182-10768305(-) 97.6 100.0
Public Domain and Genome References
Ensembl C52A11.4
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA86789 Hypothetical protein C52A11.4a [Caenorhabditis elegans] emb|CAA86769.3| Hypothetical protein C52A11.4a [Caenorhabditis elegans] ref|NP_001022038.1| Multiple PDZ domain protein family member (mpz-1) [Caenorhabditis elegans] 0.0
blast CAE59603 Hypothetical protein CBG03011 [Caenorhabditis briggsae] 0.0
blast CAE48511 Hypothetical protein C52A11.4b [Caenorhabditis elegans] emb|CAE48495.1| Hypothetical protein C52A11.4b [Caenorhabditis elegans] ref|NP_001022039.1| Multiple PDZ domain protein family member (mpz-1) [Caenorhabditis elegans] 0.0
blast CAE59603 Hypothetical protein CBG03011 [Caenorhabditis briggsae] 1.0E-115
Protein Domains
Database ID Description E-Value
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 6.1E-12
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 2.1E-17
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 1.9E-7
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 5.0E-14
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 1.5E-10
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 3.2E-21
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 8.7E-8
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 2.1E-18
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 1.7E-21
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 1.3E-11
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 2.1E-18
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 1.7E-21
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 1.3E-11
Sequence
Target Sequence 
>C. ELEGANS:193971_AT
gtgacagtaacatcagcgcctgcaacatcagtacctgagccgaatgttgtggtggagccg
attccaggtccgacaagtgcaagggaggagaggaacgatgttccaccaccggcacctcca
atgagaccaattatcactcatacgtctcccgaaggttgtgagactcaacaagaaccagct
ggattgtcaccggtcacggaagaaccttcttcgggttgtgactttatgagtgtacaagaa
gaagaacaaccacgtacaccaacaaccactacctcgagcagcaataacaacaattcactt
gcaattgatattattcatgacctgaaagaagaaggcagcgatacgttgctcgtcgagctc
aaaaaggttgttgatcagcaacttggcatgggaattggaaagagatcacgaggaattttg
gtaacttctctacaacctggatcagctgccgctgagaaattgaaagttggagatcggatt
ttagcggtcaatgcgcttccagtttctgatcagctctccgcggtgacatttgtcaaagcc
tccggtcaacggctgta

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GTGACAGTAACATCAGCGCCTGCAA 40 483 6043 Antisense
GCCTGCAACATCAGTACCTGAGCCG 476 283 6060 Antisense
TTGTGGTGGAGCCGATTCCAGGTCC 476 705 6089 Antisense
CTCATACGTCTCCCGAAGGTTGTGA 253 229 6179 Antisense
AGAACCAGCTGGATTGTCACCGGTC 674 71 6213 Antisense
GTCACCGGTCACGGAAGAACCTTCT 222 465 6228 Antisense
AGAAGGCAGCGATACGTTGCTCGTC 93 75 6372 Antisense
TAACTTCTCTACAACCTGGATCAGC 588 639 6464 Antisense
CAATGCGCTTCCAGTTTCTGATCAG 16 183 6531 Antisense
GCTCTCCGCGGTGACATTTGTCAAA 645 297 6555 Antisense
TCAAAGCCTCCGGTCAACGGCTGTA 495 629 6575 Antisense
Sequence Source Affymetrix Proprietary Database