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[193958_at] cathepsin B-like cysteine proteinase 4 precursor

Description F44C4.3 /REP_DB=WormBase Gene ID /WP=CE07251 /GEN=cpr-4 /TR=SW:P43508 /GB=AAA92327.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=cathepsin B-like cysteine proteinase 4 precursor
Cluster 6grp_highest_10_10 > 05      6grp_high1_10_10 > 50      4grp_highest_8_8 > 32      4grp_high_8_8 > 51      6grp_highest_nonorm > 08      6grp_total > 51      4grp_total > 60      6grp_highest_sub > 03_04      6grp_cgc > 83      6grp_high1_sub > 03_04      6grp_cgc_sub > 03      6grp_total_sub > Hat      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 19895
1 2 3 4 range
A 18674.5
(2.5)
P
20348.2
(3)
P
17953.7
(2.3)
P
453
(-3)
P
19895
B 18359.8
(3)
P
16586
(2.4)
P
15954.7
(2.2)
P
566.5
(-3)
P
17793
C 18274.1
(3)
P
15530.8
(2.1)
P
14477.2
(1.7)
P
620.8
(-3)
P
17653
avr 18436.1
(3)
17488.3
(2.7)
16128.5
(2.2)
546.8
(-3)
17889

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 27146
1 2 3 4 5 6 range
A 25145.4
(2.1)
P
22002.1
(1)
P
27463.5
(3)
P
27602.5
(3)
P
18701.1
(-0.2)
P
10892
(-3)
P
16711
B 18093.1
(0.2)
P
17855.1
(0.2)
P
27080.8
(3)
P
22732.4
(1.7)
P
17892.7
(0.2)
P
7527.3
(-3)
P
19554
C 20235.7
(-0.2)
P
16373.3
(-1)
P
34622.3
(3)
P
29666.9
(1.9)
P
22914.6
(0.4)
P
7476.3
(-3)
P
27146
avr 21158.1
(0.6)
18743.5
(-0.1)
29722.2
(3)
26667.3
(2.1)
19836.1
(0.2)
8631.9
(-3)
21090
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 6733
1 2 3 4 range
A 6799.4
(3)
P
4417
(0.9)
P
4693.4
(1.1)
P
66.3
(-3)
P
6733
B 5854.8
(3)
P
4096.3
(1.2)
P
3697.1
(0.7)
P
120.7
(-3)
P
5734
C 6049.3
(3)
P
4465.2
(1.4)
P
5045.8
(2)
P
104.7
(-3)
P
5945
avr 6234.5
(3)
4326.2
(1.1)
4478.8
(1.3)
97.2
(-3)
6137

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 6309
1 2 3 4 5 6 range
A 4635.4
(-0.7)
P
7825
(3)
P
5981
(0.9)
P
7000.6
(2)
P
5643.2
(0.5)
P
2651.9
(-3)
P
5173
B 6295.5
(1.7)
P
5943.2
(1.2)
P
6576
(2.1)
P
6021
(1.3)
P
7269.6
(3)
P
2806.9
(-3)
P
4463
C 7500.5
(1.8)
P
4996
(-0.6)
P
8812
(3)
P
5966
(0.3)
P
7414.8
(1.7)
P
2502.7
(-3)
P
6309
avr 6143.8
(1.7)
6254.7
(1.8)
7123
(3)
6329.2
(1.9)
6775.9
(2.5)
2653.8
(-3)
4469
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193958_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.11341
Sequence Type Exemplar sequence
Representative Public ID F44C4.3 NCBI
Target Description F44C4.3 /REP_DB=WormBase Gene ID /WP=CE07251 /GEN=cpr-4 /TR=SW:P43508 /GB=AAA92327.1 /SUBMIT=ST.LOUIS /CHR=5 /FEA=Sanger Annotation /DEF=cathepsin B-like cysteine proteinase 4 precursor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_072281(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_072281 NCBI Caenorhabditis elegans Cysteine PRotease related family member (cpr-4) (cpr-4) mRNA, complete cds. 11/11 None
SNAP00000007885 ENSEMBL cdna:SNAP chromosome:CEL140:V:6617194:6618362:1 11/11 None
GENEFINDER00000007893 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:6617194:6618362:1 11/11 None
F44C4.3.1 ENSEMBL cdna:known chromosome:CEL140:V:6617268:6618677:1 gene:F44C4.3 11/11 None
F44C4.3.2 ENSEMBL cdna:known chromosome:CEL140:V:6617268:6618438:1 gene:F44C4.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:6617354-6618362(+) 99.9 99.9
Public Domain and Genome References
Gene Title cathepsin B-like cysteine proteinase 4 precursor
Gene Symbol cpr-4
Ensembl F44C4.3
Entrez Gene 179053 Entrez gene
SwissProt P43508 EMBL-EBI
WormBase CE07251 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:259416_AT cathepsin B-like cysteine protease, putative at
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4197 cysteine-type endopeptidase activity inferred from electronic annotation QuickGO AmiGO
8234 cysteine-type peptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAA92327 Cysteine protease related protein 4 [Caenorhabditis elegans] ref|NP_504682.1| Cysteine PRotease related family member (cpr-4) [Caenorhabditis elegans] sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4 precursor (Cysteine protease-related 4) gb|AAA98783.1| cathepsin B-like cysteine proteinase gb|AAA98785.1| cathepsin B-like cysteine proteinase [Caenorhabditis elegans] 0.0
blast CAE71916 Hypothetical protein CBG18978 [Caenorhabditis briggsae] 1.0E-180
Protein Domains
Database ID Description E-Value
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 1.8E-115
Pfam IPR000668 EMBL-EBI Peptidase C1A, papain 1.8E-115
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000007885 1 24-43
GENEFINDER00000007893 1 24-43
Sequence
Target Sequence
>C. ELEGANS:193958_AT
aacacccttctctcagctgaagatgttctttcttgctgctccaactgcggatacggatgc
gagggaggatacccaatcaacgcctggaagtaccttgtcaagagcggattctgcaccgga
ggatcttacgaggctcagttcggatgcaagccatactcccttgccccatgcggagagacc
gtcggaaacgttacctggccatcttgcccagatgatggatacgataccccagcttgtgtt
aacaagtgcaccaacaagaactacaacgttgcctacaccgctgacaagcacttcggaagc
accgcttacgccgtcggaaagaaggtctcccagatccaagctgaaatcattgcccacgga
ccagtcgaggccgcattcactgtctacgaggacttctaccaatacaagaccggagtctac
gttcacaccactggacaagaactcggaggacatgccatcaga


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
AACACCCTTCTCTCAGCTGAAGATG 704 135 403 Antisense
CTGCTCCAACTGCGGATACGGATGC 503 237 438 Antisense
GGATACCCAATCAACGCCTGGAAGT 627 505 469 Antisense
GATTCTGCACCGGAGGATCTTACGA 161 433 509 Antisense
GGATCTTACGAGGCTCAGTTCGGAT 325 509 523 Antisense
TACGATACCCCAGCTTGTGTTAACA 93 645 622 Antisense
CAAGAACTACAACGTTGCCTACACC 329 183 657 Antisense
GACAAGCACTTCGGAAGCACCGCTT 326 365 685 Antisense
AGGTCTCCCAGATCCAAGCTGAAAT 36 59 725 Antisense
CAAGACCGGAGTCTACGTTCACACC 39 183 807 Antisense
AGAACTCGGAGGACATGCCATCAGA 44 73 840 Antisense
Sequence Source Affymetrix Proprietary Database