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[193955_s_at]

Description H39E23.1A /REP_DB=WormBase Gene ID /WP=CE23838 /GEN=par-1 /TR=Q9TW45 /GB=CAB54263.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=serine-threonine kinase (KIN1-SNF1-Nim1 subfamily)
Cluster 6grp_total > 02      4grp_total > 47      6grp_cgc > 41      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 243
1 2 3 4 range
A 406.6
(3)
A 		280.2
(-2.5)
A 		268.8
(-3)
A 		284.4
(-2.3)
A 		138
B 436.9
(3)
A 		210.2
(-3)
A 		253.4
(-1.9)
A 		320.4
(-0.1)
A 		227
C 376.9
(3)
A 		211.5
(-2.4)
A 		248.1
(-1.2)
A 		194.1
(-3)
A 		183
avr 406.8
(3) 		234
(-3) 		256.8
(-2.2) 		266.3
(-1.9) 		173

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 490
1 2 3 4 5 6 range
A 412.3
(0.8)
A 		566.9
(3)
A 		139.7
(-3)
A 		195
(-2.2)
A 		303.4
(-0.7)
A 		204.1
(-2.1)
A 		427
B 307.8
(1.6)
A 		375.6
(3)
A 		76.6
(-3)
A 		289.2
(1.3)
A 		206.7
(-0.4)
A 		159.6
(-1.3)
A 		299
C 468.4
(3)
P 		456.4
(2.7)
A 		267.3
(-1.2)
A 		245.5
(-1.7)
A 		198.9
(-2.7)
A 		184.3
(-3)
A 		284
avr 396.2
(1.6) 		466.3
(3) 		161.2
(-3) 		243.2
(-1.4) 		236.3
(-1.5) 		182.7
(-2.6) 		305
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 115
1 2 3 4 range
A 148
(3)
A 		60.8
(-1.9)
A 		70.3
(-1.4)
A 		41.6
(-3)
A 		106
B 139.3
(3)
A 		51.9
(-3)
A 		58.7
(-2.5)
A 		68.3
(-1.9)
A 		87
C 124.8
(3)
A 		60.8
(-1.2)
A 		86.5
(0.5)
A 		32.7
(-3)
A 		92
avr 137.4
(3) 		57.8
(-2.3) 		71.8
(-1.4) 		47.5
(-3) 		90

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 183
1 2 3 4 5 6 range
A 76
(-1.4)
A 		201.6
(3)
A 		30.4
(-3)
A 		49.5
(-2.3)
A 		91.6
(-0.9)
A 		49.7
(-2.3)
A 		171
B 107.1
(2)
A 		125
(3)
A 		18.6
(-3)
A 		76.6
(0.3)
A 		84
(0.7)
A 		59.5
(-0.7)
A 		106
C 173.6
(3)
P 		139.3
(1.3)
A 		68
(-2.1)
A 		49.4
(-3)
A 		64.4
(-2.3)
A 		61.7
(-2.4)
A 		124
avr 118.9
(1.1) 		155.3
(3) 		39
(-3) 		58.5
(-2) 		80
(-0.9) 		57
(-2.1) 		116
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193955_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13024
Sequence Type Exemplar sequence
Representative Public ID H39E23.1A NCBI
Target Description H39E23.1A /REP_DB=WormBase Gene ID /WP=CE23838 /GEN=par-1 /TR=Q9TW45 /GB=CAB54263.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=serine-threonine kinase (KIN1-SNF1-Nim1 subfamily)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001028847(11), NM_001028848(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001028847 NCBI Caenorhabditis elegans abnormal embryonic PARtitioning of cytoplasm family member (par-1) (par-1) mRNA, complete cds. 11/11 None
NM_001028848 NCBI Caenorhabditis elegans abnormal embryonic PARtitioning of cytoplasm family member (par-1) (par-1) mRNA, complete cds. 11/11 None
SNAP00000005256 ENSEMBL cdna:SNAP chromosome:CEL140:V:14115390:14116383:-1 9/11 None
GENEFINDER00000005263 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:14115390:14116383:-1 9/11 None
H39E23.1a ENSEMBL cdna:known chromosome:CEL140:V:14114624:14143724:-1 gene:H39E23.1 11/11 A 
H39E23.1b ENSEMBL cdna:known chromosome:CEL140:V:14114627:14134942:-1 gene:H39E23.1 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000005257 1/11 Cross Hyb Matching Probes None
GENEFINDER00000005259 1/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:14115389-14143707(-) 100.0 100.0
Public Domain and Genome References
Ensembl H39E23.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAB54179 Hypothetical protein H39E23.1a [Caenorhabditis elegans] emb|CAB54263.1| Hypothetical protein H39E23.1a [Caenorhabditis elegans] ref|NP_001024018.1| abnormal embryonic PARtitioning of cytoplasm family member (par-1) [Caenorhabditis elegans] 0.0
blast AAA97437 serine/threonine kinase 0.0
blast CAE61017 Hypothetical protein CBG04756 [Caenorhabditis briggsae] 0.0
blast CAB54178 Hypothetical protein H39E23.1b [Caenorhabditis elegans] emb|CAB54262.2| Hypothetical protein H39E23.1b [Caenorhabditis elegans] ref|NP_001024019.1| abnormal embryonic PARtitioning of cytoplasm family member (par-1) [Caenorhabditis elegans] gb|AAA83272.1| serine/threonine kinase 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 9.0E-76
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-76
hanks 2.2.4 CaMK Group; CaMK II KIN1/SNF1/Nim1; p78 1.0E-130
Protein Domains
Database ID Description E-Value
Pfam IPR001772 EMBL-EBI Kinase-associated, C-terminal 3.7E-23
Pfam IPR000719 EMBL-EBI Protein kinase 2.3E-101
Pfam IPR001772 EMBL-EBI Kinase-associated, C-terminal 3.7E-23
Pfam IPR000719 EMBL-EBI Protein kinase 2.3E-101
Pfam IPR001772 EMBL-EBI Kinase-associated, C-terminal 3.7E-23
Sequence
Target Sequence 
>C. ELEGANS:193955_S_AT
tggtccatcggccaacaatgcagaagcaacaatctggagcaaattgagcaaattgacgag
acgagatcataatcgagaaagtatgacccagccagtatcaggacgtgctggaaccatcgg
agcatcacaaggacagcaaaccgcggcggctcttgctgcgattcgggaacagtctggccc
aattgctccaggtgccggacaagttgcaccatcgcttccgattcatgaaggagacgtcaa
gccacgatcattgcggttcacgtggagtatgaagacgacttcttcattggctccggatga
tatgatgagagaaattcgaaaagttcttgacgctaacggttgtgactacgagcaacggga
acgatacatgattctgtgtgtgcacggtgatccgaatacagactcacttgttcaatggga
gatggaggtctgcaagttgccacgtctcagtctgaatgg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGGTCCATCGGCCAACAATGCAGAA 264 551 3051 Antisense
AGTATGACCCAGCCAGTATCAGGAC 325 63 3130 Antisense
GGAACCATCGGAGCATCACAAGGAC 707 529 3160 Antisense
TCACAAGGACAGCAAACCGCGGCGG 219 627 3175 Antisense
GCTCTTGCTGCGATTCGGGAACAGT 612 299 3199 Antisense
CGGGAACAGTCTGGCCCAATTGCTC 234 243 3214 Antisense
AATTGCTCCAGGTGCCGGACAAGTT 348 173 3231 Antisense
TCAAGCCACGATCATTGCGGTTCAC 204 625 3287 Antisense
ACTTCTTCATTGGCTCCGGATGATA 315 103 3328 Antisense
GATTCTGTGTGTGCACGGTGATCCG 157 433 3420 Antisense
AGTTGCCACGTCTCAGTCTGAATGG 72 65 3485 Antisense
Sequence Source Affymetrix Proprietary Database