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[193950_s_at] FKBP-type peptidyl-prolyl cis-trans isomerases

Description Y18D10A.19A /REP_DB=WormBase Gene ID /WP=CE21415 /GEN=fkb-8 /TR=Q9XW05 /GB=CAA22328.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=FKBP-type peptidyl-prolyl cis-trans isomerases
Cluster 6grp_highest_10_10 > 17      6grp_high1_10_10 > 61      4grp_highest_8_8 > 24      4grp_high_8_8 > 52      6grp_highest_nonorm > 52      6grp_total > 71      4grp_total > 60      6grp_highest_sub > 04      6grp_cgc > 84      6grp_high1_sub > 04      6grp_cgc_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 445
1 2 3 4 range
A 788.7
(0.6)
P 		920.7
(3)
P 		762.2
(0.1)
P 		587.3
(-3)
P 		333
B 727.1
(1.2)
P 		775.4
(2.1)
P 		818.5
(3)
P 		516.3
(-3)
P 		302
C 768.1
(2.6)
P 		787.2
(3)
P 		757.7
(2.4)
P 		476.2
(-3)
P 		311
avr 761.3
(1.7) 		827.8
(3) 		779.5
(2) 		526.6
(-3) 		301

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 807
1 2 3 4 5 6 range
A 431.3
(-2.1)
P 		580.5
(-1)
P 		895.8
(1.4)
P 		1114.1
(3)
P 		540
(-1.3)
P 		307.1
(-3)
P 		807
B 534.1
(-1.1)
P 		683.3
(0.8)
P 		716.3
(1.2)
P 		857.7
(3)
P 		650.4
(0.4)
P 		386.6
(-3)
P 		471
C 432.9
(-2.5)
P 		663.3
(0.9)
P 		749.5
(2.2)
P 		803.3
(3)
P 		541.7
(-0.9)
P 		397.6
(-3)
P 		406
avr 466.1
(-1.9) 		642.4
(-0) 		787.2
(1.5) 		925
(3) 		577.4
(-0.7) 		363.8
(-3) 		561
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 207
1 2 3 4 range
A 287.2
(3)
P 		199.9
(0.4)
P 		199.3
(0.4)
P 		86
(-3)
P 		201
B 231.9
(3)
P 		191.5
(1)
P 		189.7
(0.9)
P 		110
(-3)
P 		122
C 254.3
(2.7)
P 		226.3
(1.8)
P 		264.1
(3)
P 		80.3
(-3)
P 		184
avr 257.8
(3) 		205.9
(1.1) 		217.7
(1.5) 		92.1
(-3) 		166

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 208
1 2 3 4 5 6 range
A 79.5
(-2.9)
P 		206.4
(0.8)
P 		195.1
(0.5)
P 		282.6
(3)
P 		162.9
(-0.5)
P 		74.8
(-3)
P 		208
B 185.8
(-0.9)
P 		227.4
(1.2)
P 		173.9
(-1.5)
P 		227.2
(1.2)
P 		264.2
(3)
P 		144.2
(-3)
P 		120
C 160.5
(-0.6)
P 		202.4
(3)
P 		190.8
(2)
P 		161.5
(-0.5)
P 		175.3
(0.7)
P 		133.1
(-3)
P 		69
avr 141.9
(-1.6) 		212.1
(2.3) 		186.6
(0.9) 		223.8
(3) 		200.8
(1.7) 		117.4
(-3) 		106
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193950_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2542
Sequence Type Exemplar sequence
Representative Public ID Y18D10A.19A NCBI
Target Description Y18D10A.19A /REP_DB=WormBase Gene ID /WP=CE21415 /GEN=fkb-8 /TR=Q9XW05 /GB=CAA22328.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=FKBP-type peptidyl-prolyl cis-trans isomerases
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001026554(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001026554 NCBI Caenorhabditis elegans FK506-Binding protein family member (fkb-8) (fkb-8) mRNA, complete cds. 11/11 None
SNAP00000000429 ENSEMBL cdna:SNAP chromosome:CEL140:I:12924636:12926095:1 11/11 None
GENEFINDER00000000436 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:12924636:12926216:1 11/11 None
Y18D10A.25 ENSEMBL cdna:known chromosome:CEL140:I:12924562:12926184:1 gene:Y18D10A.25 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:12924566-12926026(+) 100.0 100.0
Public Domain and Genome References
Gene Title FKBP-type peptidyl-prolyl cis-trans isomerases
Gene Symbol fkb-8
Ensembl Y18D10A.25
Entrez Gene 173159 Entrez gene
SwissProt Q8I4E5 EMBL-EBI
WormBase CE21415 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
8233 peptidase activity inferred from electronic annotation QuickGO AmiGO
3755 peptidyl-prolyl cis-trans isomerase activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA22328 Hypothetical protein Y18D10A.25 [Caenorhabditis elegans] ref|NP_001021725.1| FK506-Binding protein family member (fkb-8) [Caenorhabditis elegans] 1.0E-172
blast T26538 hypothetical protein Y18D10A.19b - Caenorhabditis elegans 1.0E-163
blast CAA22330 Hypothetical protein Y18D10A.19 [Caenorhabditis elegans] ref|NP_001021722.1| FK506-Binding protein family member (fkb-2) [Caenorhabditis elegans] 1.0E-33
Protein Domains
Database ID Description E-Value
Pfam IPR001179 EMBL-EBI Peptidylprolyl isomerase, FKBP-type 1.9E-24
Pfam IPR001179 EMBL-EBI Peptidylprolyl isomerase, FKBP-type 5.5E-29
Sequence
Target Sequence 
>C. ELEGANS:193950_S_AT
gggcaacttgttcagtgctacatcgaaattaagcttgcggattgctacacatcttggtcc
aattacgagagccaaaatccgattatctttaaaattggattcggtgaagtcattcctggt
ttagatatcggaatccctaagatgaaagtcggtgaaatcgcaacatttcacgtgagtggc
aaatatggttacggccgcgctgggttcagaggactgattcctcgaaacgcttccctaact
tgcaaagttaggctgttcaattgctcatgggactcatatgcaaaaattggcgtcgataga
cagattctcgtccagggcgacaacgtcaccaagtcaaagaacggtcagaccgtcacctgc
cactacgtgctcatccttgtggacggaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGGCAACTTGTTCAGTGCTACATCG 662 493 316 Antisense
AAGCTTGCGGATTGCTACACATCTT 222 151 346 Antisense
CATCTTGGTCCAATTACGAGAGCCA 446 211 365 Antisense
GATTCGGTGAAGTCATTCCTGGTTT 272 433 413 Antisense
AATCGCAACATTTCACGTGAGTGGC 328 167 471 Antisense
GGCAAATATGGTTACGGCCGCGCTG 57 535 493 Antisense
CCGCGCTGGGTTCAGAGGACTGATT 573 261 510 Antisense
AGGACTGATTCCTCGAAACGCTTCC 371 53 525 Antisense
GGCTGTTCAATTGCTCATGGGACTC 157 541 566 Antisense
GATAGACAGATTCTCGTCCAGGGCG 189 423 610 Antisense
TACGTGCTCATCCTTGTGGACGGAA 684 647 679 Antisense
Sequence Source Affymetrix Proprietary Database