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[193942_s_at]

Description C45B11.1B /REP_DB=WormBase Gene ID /WP=CE20564 /TR=Q9U3M1 /GB=CAA98433.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=P21-Rho-binding domain ; Eukaryotic protein kinase domain
Cluster 6grp_highest_10_10 > 77      6grp_high1_10_10 > 77      4grp_highest_8_8 > 43      4grp_high_8_8 > 32      6grp_highest_nonorm > 93      6grp_total > 76      4grp_total > 47      6grp_highest_sub > Da      6grp_cgc > 48      6grp_high1_sub > Da      6grp_cgc_sub > Da      6grp_total_sub > Increase      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 193
1 2 3 4 range
A 389.6
(3)
P 		244.6
(-3)
P 		243.8
(-3)
P 		280
(-1.5)
P 		146
B 381.9
(3)
P 		264.6
(-2.1)
P 		328.6
(0.7)
P 		245.1
(-3)
P 		137
C 437
(3)
P 		261.3
(-2.6)
P 		249
(-3)
P 		250.9
(-2.9)
P 		188
avr 402.8
(3) 		256.8
(-3) 		273.8
(-2.3) 		258.7
(-2.9) 		146

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 295
1 2 3 4 5 6 range
A 334.2
(-2.6)
P 		329.1
(-2.7)
P 		317.8
(-3)
P 		344.1
(-2.4)
P 		420.6
(-0.6)
P 		576.2
(3)
P 		258
B 343
(-2)
P 		303.1
(-3)
P 		322.5
(-2.5)
P 		393.3
(-0.7)
P 		402.4
(-0.5)
P 		542.6
(3)
P 		240
C 325.8
(-2)
P 		313.3
(-2.3)
P 		365.8
(-1.2)
P 		401.7
(-0.4)
P 		281.1
(-3)
P 		562.6
(3)
P 		282
avr 334.3
(-2.5) 		315.2
(-3) 		335.4
(-2.5) 		379.7
(-1.4) 		368
(-1.7) 		560.5
(3) 		245
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 104
1 2 3 4 range
A 141.9
(3)
P 		53.1
(-2.3)
P 		63.7
(-1.7)
P 		41
(-3)
P 		101
B 121.8
(3)
P 		65.4
(-1.9)
P 		76.1
(-0.9)
P 		52.2
(-3)
P 		70
C 144.7
(3)
P 		75.1
(-1.1)
P 		86.8
(-0.4)
P 		42.3
(-3)
P 		102
avr 136.1
(3) 		64.5
(-1.7) 		75.5
(-1) 		45.2
(-3) 		91

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 141
1 2 3 4 5 6 range
A 61.6
(-3)
P 		117
(1.2)
P 		69.2
(-2.4)
P 		87.3
(-1)
P 		126.9
(2)
P 		140.3
(3)
P 		79
B 119.4
(-1)
P 		100.9
(-1.9)
P 		78.3
(-3)
P 		104.2
(-1.7)
P 		163.5
(1.1)
P 		202.3
(3)
P 		124
C 120.8
(-0.8)
P 		95.6
(-2.2)
P 		93.1
(-2.3)
P 		80.8
(-3)
P 		91
(-2.4)
P 		188.3
(3)
P 		108
avr 100.6
(-1.7) 		104.5
(-1.5) 		80.2
(-3) 		90.8
(-2.3) 		127.1
(-0.1) 		177
(3) 		97
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193942_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14051
Sequence Type Exemplar sequence
Representative Public ID C45B11.1B NCBI
Target Description C45B11.1B /REP_DB=WormBase Gene ID /WP=CE20564 /TR=Q9U3M1 /GB=CAA98433.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=P21-Rho-binding domain ; Eukaryotic protein kinase domain
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_073409(11), NM_073408(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_073409 NCBI Caenorhabditis elegans Temporarily Assigned Gene name family member (tag-66) (tag-66) mRNA, complete cds. 11/11 None
NM_073408 NCBI Caenorhabditis elegans Temporarily Assigned Gene name family member (tag-66) (tag-66) mRNA, complete cds. 11/11 None
SNAP00000011917 ENSEMBL cdna:SNAP chromosome:CEL140:V:11039354:11041989:-1 11/11 None
GENEFINDER00000011923 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:11039354:11041989:-1 11/11 None
C45B11.1b ENSEMBL cdna:known chromosome:CEL140:V:11039054:11042909:-1 gene:C45B11.1 11/11 A 
C45B11.1a ENSEMBL cdna:known chromosome:CEL140:V:11039342:11042909:-1 gene:C45B11.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:11039341-11042909(-) 100.0 100.0
Public Domain and Genome References
Ensembl C45B11.1
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA98433 Hypothetical protein C45B11.1b [Caenorhabditis elegans] ref|NP_505810.1| Temporarily Assigned Gene name family member (tag-66) [Caenorhabditis elegans] 0.0
blast CAA98429 Hypothetical protein C45B11.1a [Caenorhabditis elegans] ref|NP_505809.1| Temporarily Assigned Gene name family member (tag-66) [Caenorhabditis elegans] 0.0
blast CAE75146 Hypothetical protein CBG23079 [Caenorhabditis briggsae] 0.0
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 2.0E-66
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-66
hanks 2.1.17 CaMK Group; CaMK I Regulated by Ca2+/CaM and close relatives; TWITCH 2.0E-72
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 7.8E-86
Pfam IPR000095 EMBL-EBI PAK-box/P21-Rho-binding 8.7E-24
Pfam IPR000719 EMBL-EBI Protein kinase 7.8E-86
Pfam IPR000719 EMBL-EBI Protein kinase 7.8E-86
Pfam IPR000095 EMBL-EBI PAK-box/P21-Rho-binding 8.7E-24
Sequence
Target Sequence 
>C. ELEGANS:193942_S_AT
ttgtgactgcaactcgtatgactgagccacaaattgctaccatttcaaggcaggttcttg
gtgctctagactttctacacgcaagaaaagtaatacacagagacataaaaagcgactcaa
ttctactgaagcgagacggaactgtgaaactgacggatttcggtttctgtggtcaactat
ctgaagaagttcctcgtcgtcgttcgcttgttggtacgccttactggacagctgcagaag
ttattgctcgtgaaccatatgacactcgtgctgatatttggtcttttggaataatgctca
tcgagatggtagaaggagaaccgccgtttttcaatgatcagccgtttcaagcaatgaaaa
ggatacgagatgaacatgaagcaagatttagtaggcatgccaaggtatctgtggaactct
ctgaattgctttcacattgcattgtcaaagatgttaataaacggtggccagctaaagatt
tacttcgtcatccattttttgcaaaagctcagcattcttcatcaattgctcctctccttc
tacagttacaggg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTGTGACTGCAACTCGTATGACTGA 434 705 1013 Antisense
AAGGCAGGTTCTTGGTGCTCTAGAC 550 159 1059 Antisense
GTGCTCTAGACTTTCTACACGCAAG 524 477 1073 Antisense
ACTGACGGATTTCGGTTTCTGTGGT 473 91 1161 Antisense
ATCTGAAGAAGTTCCTCGTCGTCGT 413 33 1191 Antisense
CTTGTTGGTACGCCTTACTGGACAG 143 219 1219 Antisense
GTGAACCATATGACACTCGTGCTGA 425 481 1262 Antisense
GGAGAACCGCCGTTTTTCAATGATC 152 519 1327 Antisense
GTATCTGTGGAACTCTCTGAATTGC 370 455 1417 Antisense
AGCATTCTTCATCAATTGCTCCTCT 132 79 1523 Antisense
CTCCTCTCCTTCTACAGTTACAGGG 17 235 1541 Antisense
Sequence Source Affymetrix Proprietary Database