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[193935_at] 2-oxo acid dehydrogenases acyltransferase (catalytic domain)

Description C30H6.7 /REP_DB=WormBase Gene ID /WP=CE15651 /TR=O45279 /GB=CAB02813.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=2-oxo acid dehydrogenases acyltransferase (catalytic domain)
Cluster 6grp_highest_10_10 > 16      6grp_high1_10_10 > 50      4grp_highest_8_8 > 52      4grp_high_8_8 > 16      6grp_highest_nonorm > 36      6grp_total > 50      4grp_total > 39      6grp_highest_sub > 03_04      6grp_high1_sub > 03_04      6grp_total_sub > Hat      6grp_rule_based > S3      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1751
1 2 3 4 range
A 4656.9
(3)
P 		2905.8
(-3)
P 		3152.2
(-2.2)
P 		3113.4
(-2.3)
P 		1751
B 3976.1
(3)
P 		3488.2
(-0.3)
P 		3098.5
(-3)
P 		3866.6
(2.3)
P 		878
C 4195.6
(3)
P 		3384.9
(-1.7)
P 		3165.9
(-3)
P 		3750
(0.4)
P 		1030
avr 4276.2
(3) 		3259.6
(-2.4) 		3138.9
(-3) 		3576.7
(-0.7) 		1137

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2279
1 2 3 4 5 6 range
A 3749.5
(-3)
P 		4711.8
(0.1)
P 		5204.7
(1.6)
P 		5627.4
(3)
P 		3773
(-2.9)
P 		3754.7
(-3)
P 		1878
B 4314.3
(-0.3)
P 		4123.6
(-0.9)
P 		5490
(3)
P 		4718
(0.8)
P 		3533.6
(-2.5)
P 		3367.8
(-3)
P 		2122
C 4705.1
(0.2)
P 		3966
(-2)
P 		5435.1
(2.4)
P 		5647
(3)
P 		4321
(-0.9)
P 		3629.7
(-3)
P 		2017
avr 4256.3
(-0.7) 		4267.1
(-0.7) 		5376.6
(3) 		5330.8
(2.8) 		3875.9
(-2) 		3584.1
(-3) 		1793
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1240
1 2 3 4 range
A 1695.6
(3)
P 		630.8
(-2.2)
P 		824
(-1.2)
P 		455.7
(-3)
P 		1240
B 1267.9
(3)
P 		861.5
(-1.4)
P 		718
(-3)
P 		824
(-1.8)
P 		550
C 1388.9
(3)
P 		973.2
(-0.3)
P 		1103.4
(0.7)
P 		632.3
(-3)
P 		757
avr 1450.8
(3) 		821.8
(-1.6) 		881.8
(-1.2) 		637.3
(-3) 		814

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1053
1 2 3 4 5 6 range
A 691.2
(-3)
P 		1675.8
(3)
P 		1133.5
(-0.3)
P 		1427.2
(1.5)
P 		1138.5
(-0.3)
P 		914.1
(-1.6)
P 		985
B 1501.2
(3)
P 		1372.6
(-0.1)
P 		1333.1
(-1)
P 		1249.6
(-3)
P 		1435.7
(1.4)
P 		1255.8
(-2.9)
P 		252
C 1744
(3)
P 		1210.1
(-2.3)
P 		1383.3
(-0.6)
P 		1135.6
(-3)
P 		1398.2
(-0.4)
P 		1215.1
(-2.2)
P 		608
avr 1312.1
(0.8) 		1419.5
(3) 		1283.3
(0.2) 		1270.8
(-0.1) 		1324.1
(1) 		1128.3
(-3) 		291
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193935_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10230
Sequence Type Exemplar sequence
Representative Public ID C30H6.7 NCBI
Target Description C30H6.7 /REP_DB=WormBase Gene ID /WP=CE15651 /TR=O45279 /GB=CAB02813.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=2-oxo acid dehydrogenases acyltransferase (catalytic domain)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070699(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070699 NCBI Caenorhabditis elegans C30H6.7 (C30H6.7) mRNA, complete cds. 11/11 None
SNAP00000029654 ENSEMBL cdna:SNAP chromosome:CEL140:IV:17380590:17382102:1 11/11 None
GENEFINDER00000029658 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:17380590:17382102:1 11/11 None
C30H6.7 ENSEMBL cdna:known chromosome:CEL140:IV:17380588:17382180:1 gene:C30H6.7 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:17380595-17382108(+) 100.0 100.0
Public Domain and Genome References
Gene Title 2-oxo acid dehydrogenases acyltransferase (catalytic domain)
Ensembl C30H6.7
Entrez Gene 178524 Entrez gene
SwissProt O45279 EMBL-EBI
WormBase CE15651 Wormbase
Functional Annotations
Ortholog
ID Title Organism
RG-U34A:RC_AA893184_AT hypothetical protein LOC311254 rn
RAE230A:1398429_AT hypothetical protein LOC311254 rn
RAT230_2:1398429_AT hypothetical protein LOC311254 rn
RAE230B:1382234_AT Hypothetical protein LOC311254 rn
RAT230_2:1382234_AT Hypothetical protein LOC311254 rn
RG-U34C:RC_AI170418_AT Hypothetical protein LOC311254 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
8152 metabolism inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5515 protein binding inferred from electronic annotation QuickGO AmiGO
8415 acyltransferase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB02813 Hypothetical protein C30H6.7 [Caenorhabditis elegans] ref|NP_503100.1| C30H6.7 [Caenorhabditis elegans] 0.0
blast CAE57443 Hypothetical protein CBG00405 [Caenorhabditis briggsae] 1.0E-169
blast AAD30034 dihydrolipoyl dehydrogenase-binding protein [Ascaris suum] 1.0E-67
Protein Domains
Database ID Description E-Value
Pfam IPR001078 EMBL-EBI Catalytic domain of components of various dehydrogenase complexes 3.7E-102
Sequence
Target Sequence 
>C. ELEGANS:193935_AT
ctgctgtttcgctcaacgactttatcataaaagccgcagcccttgcactgaggtccgtgc
cgacagtaaatgttcgatggactccagaaggaatcggtctcggatcagtcgatatttcgg
tcgctgtggctactccaaccggccttatcactccaattgtagagaattctgatattttgg
gcgttttggcgatttctagcaaagtgaaggagttgtcgggattggcgcgagaaagcaaat
taaaaccacaacagttccagggaggatcttttacaatttcgaatcttggaatgttcggaa
gtgtgaccaacttcacagccatcataaatccaccgcaatgtgccattttgacgatcggag
gaactcgttctgaagttgtatctgttgatggacaattggagacacaaaaattaatgggtg
tcaatctttgtttcgacggacgagcaatctccgaagaatgtgcaaaacgattccttcttc
acttctccgaatcgctttctgatccggaattgctcattgctgaaccactttctccagaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTGCTGTTTCGCTCAACGACTTTAT 246 231 458 Antisense
CTGAGGTCCGTGCCGACAGTAAATG 626 225 505 Antisense
GACTCCAGAAGGAATCGGTCTCGGA 501 371 537 Antisense
TCGATATTTCGGTCGCTGTGGCTAC 263 603 566 Antisense
TTGGGCGTTTTGGCGATTTCTAGCA 441 707 634 Antisense
ACTTCACAGCCATCATAAATCCACC 235 103 767 Antisense
TAAATCCACCGCAATGTGCCATTTT 340 641 782 Antisense
GGGTGTCAATCTTTGTTTCGACGGA 496 497 873 Antisense
TCTCCGAATCGCTTTCTGATCCGGA 462 609 941 Antisense
GATCCGGAATTGCTCATTGCTGAAC 291 415 958 Antisense
CATTGCTGAACCACTTTCTCCAGAA 547 217 972 Antisense
Sequence Source Affymetrix Proprietary Database