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[193925_at] Serpins (serine protease inhibitors) (2 domains)

Description F09C6.4 /REP_DB=WormBase Gene ID /WP=CE15763 /GEN=srp-10 /TR=O45331 /GB=CAB04071.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Serpins (serine protease inhibitors) (2 domains)
Cluster 6grp_total > 90      4grp_total > 11      6grp_cgc > 0      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 91
1 2 3 4 range
A 16.9
(-3)
A 		29
(-2.2)
A 		18.3
(-2.9)
A 		103.9
(3)
A 		87
B 12.9
(-3)
A 		27
(0.1)
A 		19.6
(-1.5)
A 		40.1
(3)
A 		27
C 39
(2.6)
A 		21.3
(-1.2)
A 		13.2
(-3)
A 		40.8
(3)
A 		28
avr 22.9
(-2.2) 		25.8
(-1.8) 		17
(-3) 		61.6
(3) 		45

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 55
1 2 3 4 5 6 range
A 62.3
(3)
A 		22
(-1.7)
A 		10.9
(-3)
A 		29.5
(-0.8)
A 		22.9
(-1.6)
A 		19.1
(-2)
A 		51
B 36.1
(0.3)
A 		14.4
(-3)
A 		51.8
(2.8)
A 		40.7
(1.1)
A 		53.3
(3)
A 		25
(-1.4)
A 		39
C 7.6
(-3)
A 		39.2
(2.3)
A 		12.6
(-2.2)
A 		43.3
(3)
A 		12.4
(-2.2)
A 		30.6
(0.9)
A 		36
avr 35.3
(1.8) 		25.2
(-2.9) 		25.1
(-2.9) 		37.8
(3) 		29.5
(-0.9) 		24.9
(-3) 		13
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 11
1 2 3 4 range
A 6.2
(-2.2)
A 		6.3
(-2.1)
A 		4.8
(-3)
A 		15.2
(3)
A 		10
B 4.1
(-3)
A 		6.7
(0.5)
A 		4.5
(-2.5)
A 		8.5
(3)
A 		4
C 12.9
(3)
A 		6.1
(-1.9)
A 		4.6
(-3)
A 		6.9
(-1.3)
A 		8
avr 7.7
(0.3) 		6.4
(-1.1) 		4.6
(-3) 		10.2
(3) 		6

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 19
1 2 3 4 5 6 range
A 11.5
(3)
A 		7.8
(0.6)
A 		2.4
(-3)
A 		7.5
(0.4)
A 		6.9
(-0)
A 		4.7
(-1.5)
A 		9
B 12.6
(-0.2)
A 		4.8
(-3)
A 		12.6
(-0.2)
A 		10.8
(-0.9)
A 		21.7
(3)
A 		9.3
(-1.4)
A 		17
C 2.8
(-3)
A 		12
(3)
A 		3.2
(-2.7)
A 		8.7
(0.8)
A 		4
(-2.2)
A 		10.2
(1.8)
A 		9
avr 9
(0.6) 		8.2
(-0.4) 		6.1
(-3) 		9
(0.6) 		10.9
(3) 		8.1
(-0.5) 		5
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193925_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14433
Sequence Type Exemplar sequence
Representative Public ID F09C6.4 NCBI
Target Description F09C6.4 /REP_DB=WormBase Gene ID /WP=CE15763 /GEN=srp-10 /TR=O45331 /GB=CAB04071.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Serpins (serine protease inhibitors) (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074868(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074868 NCBI Caenorhabditis elegans SeRPin family member (srp-10) (srp-10) mRNA, complete cds. 11/11 None
SNAP00000006347 ENSEMBL cdna:SNAP chromosome:CEL140:V:16898938:16900307:1 11/11 None
GENEFINDER00000006355 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:16898938:16900307:1 11/11 None
F09C6.4 ENSEMBL cdna:known chromosome:CEL140:V:16898938:16900307:1 gene:F09C6.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:16898937-16900307(+) 100.0 100.0
Public Domain and Genome References
Gene Title Serpins (serine protease inhibitors) (2 domains)
Gene Symbol srp-10
Ensembl F09C6.4
Entrez Gene 191962 Entrez gene
SwissProt O45331 EMBL-EBI
WormBase CE15763 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04071 Hypothetical protein F09C6.4 [Caenorhabditis elegans] ref|NP_507269.1| SeRPin family member (srp-10) [Caenorhabditis elegans] 0.0
blast CAB04072 Hypothetical protein F09C6.5 [Caenorhabditis elegans] ref|NP_507268.2| SeRPin family member (srp-9) [Caenorhabditis elegans] 1.0E-157
blast AAB52318 Serpin protein 6 [Caenorhabditis elegans] ref|NP_504890.1| SeRPin family member (srp-6) [Caenorhabditis elegans] gb|AAS13530.1| serine or cysteine protease inhibitor [Caenorhabditis elegans] 5.0E-77
Protein Domains
Database ID Description E-Value
Pfam IPR000215 EMBL-EBI Serpin 1.0E-6
Pfam IPR000215 EMBL-EBI Serpin 5.3E-19
Pfam IPR000215 EMBL-EBI Serpin 3.1E-17
Sequence
Target Sequence 
>C. ELEGANS:193925_AT
tgccgttcttctcttctaaaaactcttctcgccgaatcgaatttcttcacaaaagcgaaa
tgacgaaattcaacgaaaacgctcacttcaaggtgatcagtatgccttataaagacgata
atttcgcgcttgcaatttttctgcccaaaaagagatttgcattgaaaaaggctctcaaat
cattggattctgcgagcattttgcgattgctgacttcattttcggaatgttttgttaagg
acttgggaatcaaggatgccttcgacaattgcacagctaattttgaagatttatacactt
cagcaggaggagccccattgtacattaataaggcacttcacaaggcagtcattgaggttg
acaaaatgggaaccactgcggcggctgtcacttcgcataattatgtgacactgtgcggcg
cgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TGCCGTTCTTCTCTTCTAAAAACTC 219 583 533 Antisense
CTCTTCTAAAAACTCTTCTCGCCGA 57 231 543 Antisense
CTCGCCGAATCGAATTTCTTCACAA 553 233 560 Antisense
GACGATAATTTCGCGCTTGCAATTT 439 377 646 Antisense
GCGATTGCTGACTTCATTTTCGGAA 698 287 735 Antisense
GGATGCCTTCGACAATTGCACAGCT 464 513 786 Antisense
ATACACTTCAGCAGGAGGAGCCCCA 305 25 825 Antisense
GAGGAGCCCCATTGTACATTAATAA 678 403 839 Antisense
AAGGCACTTCACAAGGCAGTCATTG 63 161 862 Antisense
CGGCTGTCACTTCGCATAATTATGT 117 243 914 Antisense
AATTATGTGACACTGTGCGGCGCGC 608 175 931 Antisense
Sequence Source Affymetrix Proprietary Database