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[193916_s_at] FKBP-type peptidyl-prolyl cis-trans isomerases

Description F31D4.3 /REP_DB=WormBase Gene ID /WP=CE15929 /GEN=fkb-6 /TR=O45418 /GB=CAB07371.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=FKBP-type peptidyl-prolyl cis-trans isomerases
Cluster 6grp_highest_10_10 > 66      6grp_high1_10_10 > 75      4grp_highest_8_8 > 12      4grp_high_8_8 > 31      6grp_highest_nonorm > 78      6grp_total > 66      4grp_total > 32      6grp_highest_sub > Da      6grp_cgc > 47      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1469
1 2 3 4 range
A 658.3
(-3)
P 		1279.7
(-0.5)
P 		1796.1
(1.7)
P 		2124.6
(3)
P 		1466
B 655.5
(-3)
P 		1341.2
(0.1)
P 		1962.3
(3)
P 		1807.6
(2.3)
P 		1307
C 693.4
(-3)
P 		1224.9
(-0.5)
P 		1976.5
(3)
P 		1901.3
(2.6)
P 		1283
avr 669.1
(-3) 		1281.9
(-0.1) 		1911.6
(2.8) 		1944.5
(3) 		1275

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 988
1 2 3 4 5 6 range
A 1387.9
(-0.8)
P 		1528.2
(0.6)
P 		1373.9
(-0.9)
P 		1160.6
(-3)
P 		1416.1
(-0.5)
P 		1779.6
(3)
P 		619
B 1307
(-3)
P 		1565.2
(-0.7)
P 		1993.4
(3)
P 		1540
(-1)
P 		1496.2
(-1.3)
P 		1843.6
(1.7)
P 		686
C 1107.5
(-3)
P 		1467.9
(-0.8)
P 		1494.9
(-0.6)
P 		1346.8
(-1.5)
P 		1309.9
(-1.8)
P 		2095.3
(3)
P 		988
avr 1267.5
(-3) 		1520.4
(-0.6) 		1620.7
(0.3) 		1349.1
(-2.2) 		1407.4
(-1.7) 		1906.2
(3) 		639
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 480
1 2 3 4 range
A 239.7
(-3)
P 		277.8
(-2)
P 		469.5
(3)
P 		311
(-1.1)
P 		230
B 209
(-3)
P 		331.3
(-0)
P 		454.7
(3)
P 		385.2
(1.3)
P 		246
C 229.5
(-3)
P 		352.2
(-1.4)
P 		688.9
(3)
P 		320.6
(-1.8)
P 		459
avr 226.1
(-3) 		320.4
(-1.2) 		537.7
(3) 		338.9
(-0.8) 		312

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 446
1 2 3 4 5 6 range
A 255.8
(-3)
P 		543.5
(3)
P 		299.2
(-2.1)
P 		294.3
(-2.2)
P 		427.3
(0.6)
P 		433.3
(0.7)
P 		288
B 454.8
(-2)
P 		521
(-0.6)
P 		484
(-1.4)
P 		407.9
(-3)
P 		607.9
(1.3)
P 		687.5
(3)
P 		280
C 410.5
(-1.1)
P 		447.9
(-0.5)
P 		380.5
(-1.5)
P 		270.8
(-3)
P 		423.9
(-0.9)
P 		701.4
(3)
P 		431
avr 373.7
(-2) 		504.1
(0.8) 		387.9
(-1.7) 		324.3
(-3) 		486.4
(0.4) 		607.4
(3) 		283
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193916_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.13972
Sequence Type Exemplar sequence
Representative Public ID F31D4.3 NCBI
Target Description F31D4.3 /REP_DB=WormBase Gene ID /WP=CE15929 /GEN=fkb-6 /TR=O45418 /GB=CAB07371.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=FKBP-type peptidyl-prolyl cis-trans isomerases
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_075625(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_075625 NCBI Caenorhabditis elegans FK506-Binding protein family member (fkb-6) (fkb-6) mRNA, complete cds. 11/11 None
SNAP00000041982 ENSEMBL cdna:SNAP chromosome:CEL140:V:20844231:20845618:1 11/11 None
GENEFINDER00000041994 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:20844231:20845618:1 11/11 None
F31D4.3 ENSEMBL cdna:known chromosome:CEL140:V:20844209:20845933:1 gene:F31D4.3 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:20844230-20845618(+) 100.0 100.0
Public Domain and Genome References
Gene Title FKBP-type peptidyl-prolyl cis-trans isomerases
Gene Symbol fkb-6
Ensembl F31D4.3
Entrez Gene 180371 Entrez gene
SwissProt O45418 EMBL-EBI
WormBase CE15929 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:248657_AT peptidyl-prolyl cis-trans isomerase, putative / FK506-binding protein, putative at
CANINE:1588562_AT similar to FK506-binding protein 4 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506 binding protein) (FKBP59) cfa
CANINE:1588409_AT similar to FK506-binding protein 4 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506 binding protein) (FKBP59) cfa
CANINE_2:CFA.14166.2.A1_A_AT similar to FK506-binding protein 4 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506 binding protein) (FKBP59) cfa
CANINE_2:CFAAFFX.23913.1.S1_S_AT similar to FK506-binding protein 4 (Peptidyl-prolyl cis-trans isomerase) (PPIase) (Rotamase) (p59 protein) (HSP binding immunophilin) (HBI) (FKBP52 protein) (52 kDa FK506 binding protein) (FKBP59) cfa
DROSOPHILA_2:1624150_AT FK506-binding protein FKBP59 dm
DROSGENOME1:141255_AT FK506-binding protein FKBP59 dm
CHICKEN:GGA.9013.1.S1_AT FK506 binding protein 4, 59kDa gga
CHICKEN:GGA.9013.2.S1_S_AT FK506 binding protein 4, 59kDa gga
HG-U133_PLUS_2:200894_S_AT FK506 binding protein 4, 59kDa hs
HG-U133A_2:200894_S_AT FK506 binding protein 4, 59kDa hs
HG-U133A:200894_S_AT FK506 binding protein 4, 59kDa hs
HG-U133A:200895_S_AT FK506 binding protein 4, 59kDa hs
HG-U133A_2:200895_S_AT FK506 binding protein 4, 59kDa hs
HG-U133_PLUS_2:200895_S_AT FK506 binding protein 4, 59kDa hs
HG-FOCUS:200895_S_AT FK506 binding protein 4, 59kDa hs
HU35KSUBC:RC_H24460_S_AT FK506 binding protein 4, 59kDa hs
HUGENEFL:M88279_AT FK506 binding protein 4, 59kDa hs
U133_X3P:G4503728_3P_A_AT FK506 binding protein 4, 59kDa hs
U133_X3P:HS.848.0.A1_3P_A_AT FK506 binding protein 4, 59kDa hs
HG-U95AV2:38729_AT FK506 binding protein 4, 59kDa hs
MOE430A:1416363_AT FK506 binding protein 4 mm
MOUSE430_2:1416363_AT FK506 binding protein 4 mm
MOUSE430A_2:1416363_AT FK506 binding protein 4 mm
MOE430A:1416362_A_AT FK506 binding protein 4 mm
MOUSE430_2:1416362_A_AT FK506 binding protein 4 mm
MOUSE430A_2:1416362_A_AT FK506 binding protein 4 mm
MU11KSUBB:MSA.28767.0_S_AT FK506 binding protein 4 mm
MU11KSUBB:MSA.42653.0_S_AT FK506 binding protein 4 mm
MU11KSUBB:X17069_S_AT FK506 binding protein 4 mm
MU11KSUBB:MSA.40688.0_F_AT FK506 binding protein 4 mm
MG-U74AV2:92809_R_AT FK506 binding protein 4 mm
MG-U74AV2:92808_F_AT FK506 binding protein 4 mm
MG-U74CV2:171417_R_AT FK506 binding protein 4 mm
MG-U74CV2:170497_AT FK506 binding protein 4 mm
MOE430B:1459808_AT FK506 binding protein 4 mm
MOUSE430_2:1459808_AT FK506 binding protein 4 mm
MOE430B:1458729_AT FK506 binding protein 4, mRNA (cDNA clone MGC:6528 IMAGE:2651490) mm
MOUSE430_2:1458729_AT FK506 binding protein 4, mRNA (cDNA clone MGC:6528 IMAGE:2651490) mm
MU11KSUBB:MSA.41385.0_S_AT FK506 binding protein 4, mRNA (cDNA clone MGC:6528 IMAGE:2651490) mm
RT-U34:RC_AI136977_G_AT FK506 binding protein 4 rn
RG-U34A:RC_AI136977_G_AT FK506 binding protein 4 rn
RT-U34:RC_AI136977_AT FK506 binding protein 4 rn
RG-U34A:RC_AI136977_AT FK506 binding protein 4 rn
RT-U34:RC_AI231547_AT FK506 binding protein 4 rn
RG-U34A:RC_AI231547_AT FK506 binding protein 4 rn
RG-U34B:RC_AI012177_AT FK506 binding protein 4 rn
RAE230A:1389844_AT FK506 binding protein 4 rn
RAT230_2:1389844_AT FK506 binding protein 4 rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB07371 Hypothetical protein F31D4.3 [Caenorhabditis elegans] ref|NP_508026.1| FK506-Binding protein family member (fkb-6) [Caenorhabditis elegans] 0.0
blast CAE60766 Hypothetical protein CBG04454 [Caenorhabditis briggsae] 0.0
blast AAD01597 peptidyl-prolyl cis-trans isomerase [Brugia malayi] 1.0E-123
Protein Domains
Database ID Description E-Value
Pfam IPR001179 EMBL-EBI Peptidylprolyl isomerase, FKBP-type 2.5E-47
Pfam IPR001179 EMBL-EBI Peptidylprolyl isomerase, FKBP-type 5.7E-15
Pfam IPR001440 EMBL-EBI TPR repeat 2.2E-6
Sequence
Target Sequence 
>C. ELEGANS:193916_S_AT
atcgtggaaccatgtacttgcagaagggaaatctcaaattggcctacaacaagtacaagc
gggccgaggaagtgttggagtatgaaaagtcaactgatcccgagaagatggccgaaagag
agacaattttgaacggagcgtatcttaatttgagtctggtttgttcgaagcaaaacgagc
aattggagtgcatcaagtggtgcgataaggtcctggaaacgaaaccaggaaacgtcaagg
cactgtatcgcaaagcaactgccctcttgaccatgaacgaagtccgagatgccatgaagt
tgttcgagaagattgtggaagtagagccggagaataaggccgccgctcaacaaatcatcg
tctgccgtaacacgatccgcgagcaaaacgagcgtgacaagaagcgcttcaagaatctat
tcgccaaaatctccaca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ATCGTGGAACCATGTACTTGCAGAA 612 33 788 Antisense
TACAACAAGTACAAGCGGGCCGAGG 486 627 832 Antisense
GTCAACTGATCCCGAGAAGATGGCC 238 465 876 Antisense
ATTTGAGTCTGGTTTGTTCGAAGCA 268 17 935 Antisense
ACTGTATCGCAAAGCAACTGCCCTC 348 97 1029 Antisense
GCCCTCTTGACCATGAACGAAGTCC 395 285 1048 Antisense
AACGAAGTCCGAGATGCCATGAAGT 244 145 1063 Antisense
GAATAAGGCCGCCGCTCAACAAATC 465 323 1119 Antisense
AACAAATCATCGTCTGCCGTAACAC 163 135 1136 Antisense
CCGTAACACGATCCGCGAGCAAAAC 545 261 1152 Antisense
GAATCTATTCGCCAAAATCTCCACA 154 329 1200 Antisense
Sequence Source Affymetrix Proprietary Database