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[193907_at] Armadillo/beta-catenin-like repeats (4 domains)

Description K05C4.6 /REP_DB=WormBase Gene ID /WP=CE19974 /GEN=hmp-2 /TR=O44326 /GB=CAB04572.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Armadillo-beta-catenin-like repeats (4 domains)
Cluster 6grp_highest_10_10 > 95      6grp_high1_10_10 > 69      4grp_highest_8_8 > 38      4grp_high_8_8 > 03      6grp_highest_nonorm > 82      6grp_total > 49      4grp_total > 05      6grp_highest_sub > Cu      6grp_cgc > 29      6grp_high1_sub > Cu      6grp_cgc_sub > Cu      6grp_total_sub > Cup      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 213
1 2 3 4 range
A 368.3
(1.1)
P 		287
(-2.4)
P 		272.5
(-3)
P 		412.1
(3)
P 		140
B 320
(-0.1)
P 		271.7
(-2.9)
P 		269.8
(-3)
P 		374.8
(3)
P 		105
C 314.4
(0.1)
P 		202.9
(-3)
P 		274.8
(-1)
P 		416.3
(3)
P 		213
avr 334.2
(0.3) 		253.9
(-3) 		272.4
(-2.2) 		401.1
(3) 		147

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 271
1 2 3 4 5 6 range
A 329.2
(-0.5)
P 		384
(1.1)
P 		248.1
(-3)
P 		256.9
(-2.7)
P 		345.7
(-0)
P 		445.1
(3)
P 		197
B 444.8
(1.2)
P 		370.6
(-0.5)
P 		267.1
(-3)
P 		317.6
(-1.8)
P 		488.9
(2.3)
P 		518.9
(3)
P 		252
C 448.1
(2.6)
P 		344
(-1.8)
P 		332.7
(-2.3)
P 		315
(-3)
P 		419.7
(1.4)
P 		456.7
(3)
P 		142
avr 407.4
(0.9) 		366.2
(-0.4) 		282.6
(-3) 		296.5
(-2.6) 		418.1
(1.3) 		473.6
(3) 		191
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 76
1 2 3 4 range
A 134.1
(3)
P 		62.3
(-2.8)
P 		71.2
(-2.1)
P 		60.3
(-3)
P 		74
B 102
(3)
P 		67.1
(-2.3)
P 		62.5
(-3)
P 		79.9
(-0.4)
P 		40
C 104.1
(3)
P 		58.3
(-3)
P 		95.8
(1.9)
P 		70.2
(-1.4)
P 		46
avr 113.4
(3) 		62.6
(-3) 		76.5
(-1.4) 		70.1
(-2.1) 		51

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 145
1 2 3 4 5 6 range
A 60.7
(-2.5)
P 		136.6
(3)
P 		54
(-3)
P 		65.1
(-2.2)
P 		104.3
(0.7)
P 		108.4
(1)
P 		83
B 154.8
(1)
P 		123.3
(-0.4)
P 		64.9
(-3)
P 		84.1
(-2.1)
P 		198.6
(3)
P 		193.5
(2.8)
P 		134
C 166.1
(3)
P 		105
(-0.6)
P 		84.7
(-1.8)
P 		63.4
(-3)
P 		135.8
(1.2)
P 		152.9
(2.2)
P 		103
avr 127.2
(1.3) 		121.6
(0.8) 		67.9
(-3) 		70.9
(-2.8) 		146.2
(2.6) 		151.6
(3) 		84
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193907_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.522
Sequence Type Exemplar sequence
Representative Public ID K05C4.6 NCBI
Target Description K05C4.6 /REP_DB=WormBase Gene ID /WP=CE19974 /GEN=hmp-2 /TR=O44326 /GB=CAB04572.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Armadillo-beta-catenin-like repeats (4 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_061165(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_061165 NCBI Caenorhabditis elegans HuMPback (dorsal lumps) family member (hmp-2) (hmp-2) mRNA, complete cds. 11/11 None
SNAP00000018540 ENSEMBL cdna:SNAP chromosome:CEL140:I:14745821:14750640:1 11/11 None
GENEFINDER00000018552 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:14745821:14750640:1 11/11 None
K05C4.6 ENSEMBL cdna:known chromosome:CEL140:I:14747687:14750787:1 gene:K05C4.6 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:14747639-14750571(+) 100.0 100.0
Public Domain and Genome References
Gene Title Armadillo/beta-catenin-like repeats (4 domains)
Gene Symbol hmp-2
Ensembl K05C4.6
Entrez Gene 173338 Entrez gene
SwissProt O44326 EMBL-EBI
WormBase CE19974 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1605226_AT similar to catenin (cadherin-associated protein), beta 1, 88kDa cfa
CANINE:1589978_S_AT similar to catenin (cadherin-associated protein), beta 1, 88kDa cfa
CANINE_2:CFA.415.1.S1_AT similar to catenin (cadherin-associated protein), beta 1, 88kDa cfa
CANINE_2:CFAAFFX.8762.1.S1_S_AT similar to catenin (cadherin-associated protein), beta 1, 88kDa cfa
DROSOPHILA_2:1629020_S_AT armadillo dm
DROSGENOME1:154145_AT armadillo dm
CHICKEN:GGA.4283.1.S1_AT catenin (cadherin-associated protein), beta 1, 88kDa gga
HG-U133_PLUS_2:201533_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U133A:201533_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-FOCUS:201533_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U133A_2:201533_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
HUGENEFL:X87838_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
U133_X3P:G4503130_3P_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
U133_X3P:HS2.382858.3.S1_3P_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
U133_X3P:HS2.171271.2.S1_3P_S_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U133_PLUS_2:1554411_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U133_PLUS_2:1570507_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U95AV2:40777_AT catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U133_PLUS_2:242558_AT Catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U133B:242558_AT Catenin (cadherin-associated protein), beta 1, 88kDa hs
HU35KSUBD:RC_R60044_AT Catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U133B:223679_AT Catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U133_PLUS_2:223679_AT Catenin (cadherin-associated protein), beta 1, 88kDa hs
U133_X3P:G11493474_RC_3P_AT Catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U95C:54930_AT Catenin (cadherin-associated protein), beta 1, 88kDa hs
HG-U95D:82077_AT Catenin (cadherin-associated protein), beta 1, 88kDa hs
U133_X3P:HS.162459.0.A1_3P_AT Catenin (cadherin-associated protein), beta 1, 88kDa hs
MOUSE430A_2:1450008_A_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MOUSE430_2:1450008_A_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MOE430A:1450008_A_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MOUSE430A_2:1420811_A_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MOE430A:1420811_A_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MOUSE430_2:1420811_A_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MU11KSUBA:M90364_S_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MG-U74AV2:160430_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MOE430A:1430533_A_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MOUSE430A_2:1430533_A_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MOUSE430_2:1430533_A_AT catenin (cadherin associated protein), beta 1, 88kDa mm
MU19KSUBA:TC24306_AT Catenin (cadherin associated protein), beta 1, 88kDa, mRNA (cDNA clone IMAGE:3156732) mm
MU19KSUBA:TC24307_AT Catenin (cadherin associated protein), beta 1, 88kDa, mRNA (cDNA clone IMAGE:3156732) mm
MU19KSUBC:TC39397_AT Catenin (cadherin associated protein), beta 1, 88kDa, mRNA (cDNA clone IMAGE:3156732) mm
RAE230A:1369733_AT catenin (cadherin associated protein), beta 1, 88kDa rn
RAT230_2:1369733_AT catenin (cadherin associated protein), beta 1, 88kDa rn
RAE230A:1373067_AT Catenin beta rn
RAT230_2:1373067_AT Catenin beta rn
RAE230A:1375284_AT Catenin beta rn
RAT230_2:1375284_AT Catenin beta rn
RG-U34C:RC_AA819695_AT Catenin beta rn
RG-U34B:RC_AI013204_AT Catenin beta rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
45944 positive regulation of transcription from RNA polymerase II promoter inferred from direct assay QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5913 cell-cell adherens junction inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3713 transcription coactivator activity inferred from direct assay QuickGO AmiGO
5515 protein binding inferred from physical interaction QuickGO AmiGO
45294 alpha-catenin binding inferred from physical interaction QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04572 Hypothetical protein K05C4.6 [Caenorhabditis elegans] ref|NP_493566.1| HuMPback (dorsal lumps) family member (hmp-2) [Caenorhabditis elegans] gb|AAB94552.1| HMP-2 [Caenorhabditis elegans] 0.0
blast CAE72561 Hypothetical protein CBG19745 [Caenorhabditis briggsae] 0.0
blast CAB04573 Hypothetical protein K05C4.7 [Caenorhabditis elegans] ref|NP_493565.1| K05C4.7 [Caenorhabditis elegans] 1.0E-157
blast CAB04573 Hypothetical protein K05C4.7 [Caenorhabditis elegans] ref|NP_493565.1| K05C4.7 [Caenorhabditis elegans] 1.0E-152
Protein Domains
Database ID Description E-Value
Pfam IPR000225 EMBL-EBI Armadillo 5.5E-7
Pfam IPR000225 EMBL-EBI Armadillo 5.5E-7
Pfam IPR000225 EMBL-EBI Armadillo 5.5E-7
Sequence
Target Sequence 
>C. ELEGANS:193907_AT
tcgaaggagctgtctcggctcttcatcagctcgcgaatcatccggcagtcgctgcagcat
gctgtgatgatattggacaagtcggaaatccagaatgtccaccattcttggatcttctcc
atcgtcttctggctcatccgagactcggatccatggatgatgaagttctcgaacgcgaga
ttcttgggcttctctatcagttgagcaagcggccagacggagcccgtgctgttgagagta
ctggagttagtgctcttttaatggaatctcgtggctcacagtacaaatcagtcgtcactt
atgcgaatggagtgttgagtaatttgaagagaggagattcagctgccatcatgaatatgt
ctaattcgtacgactacgagatgagtggaagtgctgcggattggcaacgtgatgggctgg
aacgagagcttttcgctgaaatgtatccgacaaacgacggcggacactcggaatc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCGAAGGAGCTGTCTCGGCTCTTCA 298 601 1508 Antisense
GCAGTCGCTGCAGCATGCTGTGATG 684 311 1552 Antisense
GAATGTCCACCATTCTTGGATCTTC 688 331 1600 Antisense
GAACGCGAGATTCTTGGGCTTCTCT 141 347 1678 Antisense
TCAGTTGAGCAAGCGGCCAGACGGA 546 623 1704 Antisense
AGCCCGTGCTGTTGAGAGTACTGGA 428 81 1728 Antisense
TGGAATCTCGTGGCTCACAGTACAA 219 547 1769 Antisense
GAGAGGAGATTCAGCTGCCATCATG 322 395 1836 Antisense
GGAAGTGCTGCGGATTGGCAACGTG 694 531 1894 Antisense
GGGCTGGAACGAGAGCTTTTCGCTG 160 493 1921 Antisense
CAAACGACGGCGGACACTCGGAATC 367 191 1958 Antisense
Sequence Source Affymetrix Proprietary Database