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[193892_at] Serpins (serine protease inhibitors) (2 domains)

Description F09C6.5 /REP_DB=WormBase Gene ID /WP=CE15764 /GEN=srp-9 /TR=O45332 /GB=CAB04072.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Serpins (serine protease inhibitors) (2 domains)
Cluster 6grp_total > 70      4grp_total > 40      6grp_cgc > 95      6grp_cgc_sub > 04      6grp_total_sub > Hat      6grp_rule_based > S4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3
1 2 3 4 range
A 3
(-2.7)
A 		2.9
(-3)
A 		5.2
(3)
A 		5.1
(2.7)
A 		2
B 1.8
(-3)
A 		5.1
(3)
A 		4.1
(1.2)
A 		3.2
(-0.5)
A 		3
C 2.1
(-3)
A 		2.6
(0.3)
A 		3
(3)
A 		2.9
(2.3)
A 		1
avr 2.3
(-3) 		3.5
(1) 		4.1
(3) 		3.7
(1.7) 		2

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 5
1 2 3 4 5 6 range
A 2.9
(-2.2)
A 		2.7
(-3)
A 		3.2
(-1)
A 		4.2
(3)
A 		3.3
(-0.6)
A 		3.2
(-1)
A 		2
B 2.4
(-2)
A 		2.1
(-2.4)
A 		2.9
(-1.4)
A 		6.4
(3)
A 		2.1
(-2.4)
A 		1.6
(-3)
A 		5
C 2.4
(-2)
A 		2.8
(-0.9)
A 		2.6
(-1.4)
A 		4.3
(3)
A 		2.8
(-0.9)
A 		2
(-3)
A 		2
avr 2.6
(-2.3) 		2.5
(-2.6) 		2.9
(-1.7) 		5
(3) 		2.7
(-2.1) 		2.3
(-3) 		3
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1
1 2 3 4 range
A 1.1
(0.8)
A 		0.6
(-3)
A 		1.4
(3)
A 		0.7
(-2.3)
A 		1
B 0.6
(-3)
A 		1.3
(3)
A 		1
(0.4)
A 		0.7
(-2.1)
A 		1
C 0.7
(-0.6)
A 		0.7
(-0.6)
A 		1
(3)
A 		0.5
(-3)
A 		1
avr 0.8
(-0.6) 		0.9
(0.6) 		1.1
(3) 		0.6
(-3) 		1

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1
1 2 3 4 5 6 range
A 0.5
(-3)
A 		1
(2)
A 		0.7
(-1)
A 		1.1
(3)
A 		1
(2)
A 		0.8
(0)
A 		1
B 0.8
(-1.9)
A 		0.7
(-2.5)
A 		0.7
(-2.5)
A 		1.7
(3)
A 		0.8
(-1.9)
A 		0.6
(-3)
A 		1
C 0.9
(3)
A 		0.8
(0)
A 		0.7
(-3)
A 		0.9
(3)
A 		0.9
(3)
A 		0.7
(-3)
A 		0
avr 0.7
(-3) 		0.8
(-1.8) 		0.7
(-3) 		1.2
(3) 		0.9
(-0.6) 		0.7
(-3) 		1
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193892_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.14325
Sequence Type Exemplar sequence
Representative Public ID F09C6.5 NCBI
Target Description F09C6.5 /REP_DB=WormBase Gene ID /WP=CE15764 /GEN=srp-9 /TR=O45332 /GB=CAB04072.1 /SUBMIT=HINXTON /CHR=5 /FEA=Sanger Annotation /DEF=Serpins (serine protease inhibitors) (2 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_074867(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_074867 NCBI Caenorhabditis elegans SeRPin family member (srp-9) (srp-9) mRNA, complete cds. 11/11 None
SNAP00000006346 ENSEMBL cdna:SNAP chromosome:CEL140:V:16896810:16898133:-1 11/11 None
GENEFINDER00000006367 ENSEMBL cdna:GeneFinder chromosome:CEL140:V:16896810:16898506:-1 11/11 None
F09C6.5 ENSEMBL cdna:known chromosome:CEL140:V:16896810:16898133:-1 gene:F09C6.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrV:16896809-16898133(-) 100.0 100.0
Public Domain and Genome References
Gene Title Serpins (serine protease inhibitors) (2 domains)
Gene Symbol srp-9
Ensembl F09C6.5
Entrez Gene 191961 Entrez gene
SwissProt O45332 EMBL-EBI
WormBase CE31848 Wormbase
Functional Annotations
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
4867 serine-type endopeptidase inhibitor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04072 Hypothetical protein F09C6.5 [Caenorhabditis elegans] ref|NP_507268.2| SeRPin family member (srp-9) [Caenorhabditis elegans] 0.0
blast CAB04072 Hypothetical protein F09C6.5 [Caenorhabditis elegans] ref|NP_507268.2| SeRPin family member (srp-9) [Caenorhabditis elegans] 1.0E-166
blast CAB04071 Hypothetical protein F09C6.4 [Caenorhabditis elegans] ref|NP_507269.1| SeRPin family member (srp-10) [Caenorhabditis elegans] 1.0E-157
blast CAB04072 Hypothetical protein F09C6.5 [Caenorhabditis elegans] ref|NP_507268.2| SeRPin family member (srp-9) [Caenorhabditis elegans] 1.0E-155
blast CAB04071 Hypothetical protein F09C6.4 [Caenorhabditis elegans] ref|NP_507269.1| SeRPin family member (srp-10) [Caenorhabditis elegans] 1.0E-121
blast AAB52318 Serpin protein 6 [Caenorhabditis elegans] ref|NP_504890.1| SeRPin family member (srp-6) [Caenorhabditis elegans] gb|AAS13530.1| serine or cysteine protease inhibitor [Caenorhabditis elegans] 9.0E-85
Protein Domains
Database ID Description E-Value
Pfam IPR000215 EMBL-EBI Serpin 5.1E-66
Pfam IPR000215 EMBL-EBI Serpin 1.1E-53
Pfam IPR000215 EMBL-EBI Serpin 1.1E-53
Sequence
Target Sequence 
>C. ELEGANS:193892_AT
agttgggaggtgtcgtttttctctgctaaaaaaacttctcgccaagttgaatttcttcac
atgtgcgaaatgacaaaattcaacgagaacgctcacttcaaggtcatcagtatgccgtac
aaagacgagaatttcgctcttgcaatttttttgcccaaaaagagatttgcgttgaaaaag
gctctcaaatcattggattctgcgagcattttgcaattgctcacttcattttcagaatgt
tttgttaagatcgcgattccaaaatggagcattgaaacagatatggacatcggcgcggca
cttcaggacttgggaatcaaggatgcctttgacaattgtgctgcaaattttgaagatatg
tacacttcggcaggaggcgacccattgtacatcagtaaagcacttcacaaggcaatcatt
gaggtttgtggtagatatgatagtgaaggttcgaaattttttgattttaaggttgacaaa
atgggaaccactgctgcggctgtcacatcgcttatgtatacggacggcgtcccacagct

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGTTGGGAGGTGTCGTTTTTCTCTG 103 63 502 Antisense
TCTGCTAAAAAAACTTCTCGCCAAG 709 603 523 Antisense
TTCAAGGTCATCAGTATGCCGTACA 499 685 598 Antisense
GACGAGAATTTCGCTCTTGCAATTT 440 377 625 Antisense
ATGTTTTGTTAAGATCGCGATTCCA 335 47 738 Antisense
AAACAGATATGGACATCGGCGCGGC 530 127 776 Antisense
GCGGCACTTCAGGACTTGGGAATCA 587 291 796 Antisense
AGGATGCCTTTGACAATTGTGCTGC 8 57 821 Antisense
AGGCGACCCATTGTACATCAGTAAA 630 45 876 Antisense
GGCTGTCACATCGCTTATGTATACG 332 541 999 Antisense
TGTATACGGACGGCGTCCCACAGCT 563 557 1016 Antisense
Sequence Source Affymetrix Proprietary Database