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[193876_at] transforming growth factor beta proteins

Description B0412.2 /REP_DB=WormBase Gene ID /WP=CE01758 /GEN=daf-7 /TR=SW:P92172 /GB=AAB52554.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=transforming growth factor beta proteins
Cluster 6grp_highest_10_10 > 40      6grp_high1_10_10 > 16      4grp_highest_8_8 > 57      4grp_high_8_8 > 34      6grp_highest_nonorm > 41      6grp_total > 15      4grp_total > 46      6grp_highest_sub > De      6grp_cgc > 23      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1782
1 2 3 4 range
A 2406.5
(3)
P
1424.8
(-1.3)
P
1031.1
(-3)
P
1181.2
(-2.3)
P
1375
B 2812.7
(3)
P
1747.4
(-0.7)
P
1077.4
(-2.9)
P
1062.2
(-3)
P
1751
C 2290.4
(3)
P
1757.1
(0.4)
P
1063.7
(-3)
P
1062.6
(-3)
P
1228
avr 2503.2
(3)
1643.1
(-0.6)
1057.4
(-3)
1102
(-2.8)
1446

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 778
1 2 3 4 5 6 range
A 902.4
(0.7)
P
1166.3
(3)
P
646
(-1.6)
P
694.6
(-1.1)
P
480.7
(-3)
P
545.3
(-2.4)
P
686
B 1036.7
(3)
P
829.7
(0.7)
P
592.4
(-2)
P
623.3
(-1.7)
P
506.1
(-3)
P
522.7
(-2.8)
P
531
C 1258.5
(3)
P
716.9
(-1.4)
P
847.4
(-0.4)
P
528.5
(-3)
P
621.2
(-2.2)
P
523
(-3)
P
736
avr 1065.9
(3)
904.3
(1.2)
695.3
(-1.2)
615.5
(-2)
536
(-2.9)
530.3
(-3)
536
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 724
1 2 3 4 range
A 876.2
(3)
P
309.3
(-1.8)
P
269.6
(-2.2)
P
172.9
(-3)
P
703
B 896.9
(3)
P
431.6
(-1.2)
P
249.7
(-2.8)
P
226.4
(-3)
P
671
C 758.2
(3)
P
505.2
(0.4)
P
370.7
(-1)
P
179.2
(-3)
P
579
avr 843.8
(3)
415.4
(-0.9)
296.7
(-2)
192.8
(-3)
651

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 360
1 2 3 4 5 6 range
A 166.4
(-2.3)
P
414.8
(3)
P
140.7
(-2.8)
P
176.2
(-2.1)
P
145.1
(-2.7)
P
132.8
(-3)
P
282
B 360.7
(3)
P
276.2
(0.7)
P
143.9
(-3)
P
165.1
(-2.4)
P
205.6
(-1.3)
P
194.9
(-1.6)
P
217
C 466.5
(3)
P
218.7
(-1.1)
P
215.7
(-1.2)
P
106.3
(-3)
P
201
(-1.4)
P
175.1
(-1.9)
P
360
avr 331.2
(3)
303.2
(2.1)
166.8
(-2.4)
149.2
(-3)
183.9
(-1.9)
167.6
(-2.4)
182
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193876_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8170
Sequence Type Exemplar sequence
Representative Public ID B0412.2 NCBI
Target Description B0412.2 /REP_DB=WormBase Gene ID /WP=CE01758 /GEN=daf-7 /TR=SW:P92172 /GB=AAB52554.1 /SUBMIT=ST.LOUIS /CHR=3 /FEA=Sanger Annotation /DEF=transforming growth factor beta proteins
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_064864(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_064864 NCBI Caenorhabditis elegans abnormal DAuer Formation family member (daf-7) (daf-7) mRNA, complete cds. 11/11 None
SNAP00000002844 ENSEMBL cdna:SNAP chromosome:CEL140:III:811931:813268:1 11/11 None
GENEFINDER00000002850 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:811931:813268:1 11/11 None
B0412.2 ENSEMBL cdna:known chromosome:CEL140:III:811821:813757:1 gene:B0412.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:811930-813268(+) 100.0 100.0
Public Domain and Genome References
Gene Title transforming growth factor beta proteins
Gene Symbol daf-7
Ensembl B0412.2
Entrez Gene 175237 Entrez gene
SwissProt P92172 EMBL-EBI
WormBase CE01758 Wormbase
Functional Annotations
Ortholog
ID Title Organism
HG-U133_PLUS_2:216860_S_AT growth differentiation factor 11 hs
HG-U133A_2:216860_S_AT growth differentiation factor 11 hs
HG-FOCUS:216860_S_AT growth differentiation factor 11 hs
HG-U133A:216860_S_AT growth differentiation factor 11 hs
HU35KSUBA:RC_AA053348_R_AT growth differentiation factor 11 hs
HU35KSUBA:N52656_S_AT growth differentiation factor 11 hs
HU35KSUBB:RC_W93682_AT growth differentiation factor 11 hs
U133_X3P:HS.34941.2.S1_3P_A_AT growth differentiation factor 11 hs
HG-U95B:50113_AT growth differentiation factor 11 hs
HG-U133_PLUS_2:216854_AT growth differentiation factor 11 hs
HG-U133A_2:216854_AT growth differentiation factor 11 hs
HG-U133A:216854_AT growth differentiation factor 11 hs
HG-U95AV2:37881_AT growth differentiation factor 11 hs
MOUSE430_2:1427723_AT growth differentiation factor 11 mm
MOUSE430A_2:1427723_AT growth differentiation factor 11 mm
MOE430A:1427723_AT growth differentiation factor 11 mm
MG-U74AV2:101814_AT growth differentiation factor 11 mm
Protein Similarities
Method ID Description E-Value
blast AAB52554 Abnormal dauer formation protein 7 [Caenorhabditis elegans] ref|NP_497265.1| abnormal DAuer Formation family member (daf-7) [Caenorhabditis elegans] sp|P92172|DAF7_CAEEL Dauer larva development regulatory growth factor daf-7 precursor (Abnormal dauer formation protein 7) gb|AAC47390.1| dauer larva development regulatory growth factor [Caenorhabditis elegans] gb|AAC47389.1| DAF-7 [Caenorhabditis elegans] 0.0
blast CAE57030 Hypothetical protein CBG24910 [Caenorhabditis briggsae] 6.0E-84
blast AAX36084 transforming growth factor beta [Ancylostoma caninum] gb|AAX36082.1| transforming growth factor beta [Ancylostoma caninum] 5.0E-54
Protein Domains
Database ID Description E-Value
Pfam IPR001839 EMBL-EBI Transforming growth factor beta 2.0E-20
Sequence
Target Sequence
>C. ELEGANS:193876_AT
gttggttcacaatttctccgatccaaggtatcttcgtcaaggcaatgctcgacgggcgca
acgttgcccttcatccccaacagaccactgctgacgttgacaacatgcgtcttcagctct
ccactcgtccaaaggggtcccgcaaacgccgttctcatgccaaaccggtttgcaatgccg
aagcacagtccaaggggtgctgcttgtatgacctcgaaatcgaattcgaaaagatcggat
gggactggatcgtggccccaccacgttacaatgcctacatgtgccgcggggattgccact
ataacgcacaccacttcaacttggcggaaaccggacacagcaagatcatgcgcgcagctc
acaaagtctccaatcctgagatcggatactgctgccatccaaccgagtacgactacatca
agctgatctatgtcaaccgcgacggacgcgtctcaatcgccaatgtcaacgg


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
GTTGGTTCACAATTTCTCCGATCCA 90 437 563 Antisense
TTGACAACATGCGTCTTCAGCTCTC 522 705 659 Antisense
AATGCCGAAGCACAGTCCAAGGGGT 204 167 736 Antisense
GTGCTGCTTGTATGACCTCGAAATC 464 479 759 Antisense
ACGTTACAATGCCTACATGTGCCGC 106 95 825 Antisense
GCCGCGGGGATTGCCACTATAACGC 514 285 845 Antisense
TAACGCACACCACTTCAACTTGGCG 300 639 864 Antisense
TGAGATCGGATACTGCTGCCATCCA 479 567 939 Antisense
TGCCATCCAACCGAGTACGACTACA 289 585 955 Antisense
CAAGCTGATCTATGTCAACCGCGAC 643 185 981 Antisense
GCGTCTCAATCGCCAATGTCAACGG 562 291 1010 Antisense
Sequence Source Affymetrix Proprietary Database