::: Dauer Metabolic Database :::

[193860_s_at] glyceraldehyde 3-phosphate dehydrogenase 4 /// glyceraldehyde 3-phosphate dehydrogenase 1

NetAffx Links

Cluster Members
Consensus/Exemplar
Group Members

GeneChip Array Information

Probe Set ID

193860_s_at

GeneChip Array

C. elegans Genome Array

Organism Common Name

Nematode

Probe Design Information

Transcript ID(Array Design)

affy.Ce.2890

Sequence Type

Exemplar sequence

Representative Public ID

F33H1.2 NCBI

Target Description

F33H1.2 /REP_DB=WormBase Gene ID /WP=CE01568 /GEN=gpd-4 /TR=SW:P17331 /GB=CAA88697.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=glyceraldehyde 3-phosphate dehydrogenase 4

Cluster Evidence

This cluster is supported by a Sanger Annotation.

Annotation Method Description

Annotation Description

This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).

Annotation Grade

This is a grade A annotation.

Annotation Transcript Cluster (# of Matching Probes)

NM_063791(11), NM_063836(11)

Transcript Assignments

Representative Transcript	Description	Matching Probes	Related Probesets by Grade
NM_063791 NCBI	Caenorhabditis elegans GPD (glyceraldehyde 3-phosphate dehydrogenase) family member (gpd-4) (gpd-4) mRNA, complete cds.	11/11	None
NM_063836 NCBI	Caenorhabditis elegans GPD (glyceraldehyde 3-phosphate dehydrogenase) family member (gpd-1) (gpd-1) mRNA, complete cds.	11/11	None
SNAP00000009658 ENSEMBL	cdna:SNAP chromosome:CEL140:II:10394047:10395172:1	11/11	None
GENEFINDER00000009664 ENSEMBL	cdna:GeneFinder chromosome:CEL140:II:10394047:10395172:1	11/11	None
SNAP00000027288 ENSEMBL	cdna:SNAP chromosome:CEL140:II:10171191:10172316:1	11/11	None
GENEFINDER00000027294 ENSEMBL	cdna:GeneFinder chromosome:CEL140:II:10171191:10172316:1	11/11	None
F33H1.2 ENSEMBL	cdna:known chromosome:CEL140:II:10171181:10172350:1 gene:F33H1.2	11/11	None
T09F3.3.2 ENSEMBL	cdna:known chromosome:CEL140:II:10393671:10395241:1 gene:T09F3.3	11/11	None
T09F3.3.1 ENSEMBL	cdna:known chromosome:CEL140:II:10394024:10395241:1 gene:T09F3.3	11/11	None
T09F3.3.3 ENSEMBL	cdna:known chromosome:CEL140:II:10394039:10395241:1 gene:T09F3.3	11/11	None

Annotation Notes

There are no noteworthy cross hybridizing mRNAs found for this probe set.

Genomic Alignment of Consensus/Exemplar Sequence

Assembly

Wormbase March 2004

Alignment(s)

Position	Identity	Coverage	Cytoband
chrII:10171187-10172313(+)	100.0	100.0
chrII:10394043-10395169(+)	99.03	99.03

Public Domain and Genome References

Gene Title

glyceraldehyde 3-phosphate dehydrogenase 4
glyceraldehyde 3-phosphate dehydrogenase 1

Gene Symbol

gpd-4
gpd-1

Ensembl

F33H1.2
T09F3.3

Entrez Gene

174578 Entrez gene
174603 Entrez gene

SwissProt

P17331 EMBL-EBI
P04970 EMBL-EBI

WormBase

CE01568 Wormbase
CE02343 Wormbase

Functional Annotations

Ortholog

ID	Title	Organism
ATH1-121501:262939_S_AT	glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative / NAD-dependent glyceraldehyde-3-phosphate dehydrogenase, putative	at
ATGENOME1:17463_AT	glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative / NAD-dependent glyceraldehyde-3-phosphate dehydrogenase, putative	at
ATH1-121501:262939_S_AT	glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative / NAD-dependent glyceraldehyde-3-phosphate dehydrogenase, putative	at
ATGENOME1:17463_AT	glyceraldehyde 3-phosphate dehydrogenase, cytosolic, putative / NAD-dependent glyceraldehyde-3-phosphate dehydrogenase, putative	at
CANINE_2:CFA.16332.1.S1_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.11198.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.12458.1.S1_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.12458.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.13010.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.15326.1.S1_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.15326.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.22564.1.S1_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.23015.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.26731.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.30894.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.5711.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.8103.1.S1_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFA.16332.1.S1_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.11198.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.12458.1.S1_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.12458.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.13010.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.15326.1.S1_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.15326.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.22564.1.S1_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.23015.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.26731.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.30894.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.5711.1.S1_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
CANINE_2:CFAAFFX.8103.1.S1_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	cfa
MOUSE430A_2:1447999_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOE430A:1447999_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430_2:1447999_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MU11KSUBB:MSA.677.0_F_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74AV2:101214_F_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74CV2:137249_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74AV2:162176_R_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOE430A:1418625_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430A_2:1418625_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430_2:1418625_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430A_2:1447999_X_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOE430A:1447999_X_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430_2:1447999_X_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MU11KSUBB:MSA.677.0_F_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74AV2:101214_F_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74CV2:137249_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74AV2:162176_R_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOE430A:1418625_S_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430A_2:1418625_S_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430_2:1418625_S_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430A_2:1447999_X_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MOE430A:1447999_X_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MOUSE430_2:1447999_X_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MU11KSUBB:MSA.677.0_F_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MG-U74AV2:101214_F_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MG-U74CV2:137249_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MG-U74AV2:162176_R_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MG-U74CV2:169710_I_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MOE430A:1418625_S_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MOUSE430A_2:1418625_S_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MOUSE430_2:1418625_S_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MU19KSUBC:TC35630_F_AT	Glyceraldehyde-3-phosphate dehydrogenase, mRNA (cDNA clone MGC:106375 IMAGE:2649847)	mm
MU19KSUBC:TC35630_I_AT	Glyceraldehyde-3-phosphate dehydrogenase, mRNA (cDNA clone MGC:106375 IMAGE:2649847)	mm
MOUSE430A_2:1447999_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOE430A:1447999_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430_2:1447999_X_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MU11KSUBB:MSA.677.0_F_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74AV2:101214_F_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74CV2:137249_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74AV2:162176_R_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOE430A:1418625_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430A_2:1418625_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430_2:1418625_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430A_2:1447999_X_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOE430A:1447999_X_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430_2:1447999_X_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MU11KSUBB:MSA.677.0_F_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74AV2:101214_F_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74CV2:137249_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MG-U74AV2:162176_R_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOE430A:1418625_S_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430A_2:1418625_S_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430_2:1418625_S_AT	glyceraldehyde-3-phosphate dehydrogenase	mm
MOUSE430A_2:1447999_X_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MOE430A:1447999_X_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MOUSE430_2:1447999_X_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MU11KSUBB:MSA.677.0_F_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MG-U74AV2:101214_F_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MG-U74CV2:137249_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MG-U74AV2:162176_R_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MG-U74CV2:169710_I_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MOE430A:1418625_S_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MOUSE430A_2:1418625_S_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MOUSE430_2:1418625_S_AT	similar to Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)	mm
MU19KSUBC:TC35630_F_AT	Glyceraldehyde-3-phosphate dehydrogenase, mRNA (cDNA clone MGC:106375 IMAGE:2649847)	mm
MU19KSUBC:TC35630_I_AT	Glyceraldehyde-3-phosphate dehydrogenase, mRNA (cDNA clone MGC:106375 IMAGE:2649847)	mm
RT-U34:M17701_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	rn
RG-U34A:M17701_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	rn
RAE230A:1367557_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	rn
RAT230_2:1367557_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	rn
RT-U34:M17701_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	rn
RG-U34A:M17701_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	rn
RAE230A:1367557_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	rn
RAT230_2:1367557_S_AT	similar to glyceraldehyde-3-phosphate dehydrogenase	rn
YEAST_2:1775388_AT	Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall	Sc
YEAST_2:1775388_AT	Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall	Sc

Gene Ontology

GO Biological Process (view graph)
ID	Description	Evidence	Links
6006	glucose metabolism	inferred from electronic annotation	QuickGO AmiGO
6096	glycolysis	inferred from electronic annotation	QuickGO AmiGO
GO Molecular Function (view graph)
ID	Description	Evidence	Links
4365	glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) activity	inferred from electronic annotation	QuickGO AmiGO
8943	glyceraldehyde-3-phosphate dehydrogenase activity	inferred from electronic annotation	QuickGO AmiGO

Protein Similarities

Method	ID	Description	E-Value
blast	CAA88697	Hypothetical protein F33H1.2 [Caenorhabditis elegans] emb\|CAA36899.1\| gpd-4 [Caenorhabditis elegans] ref\|NP_496192.1\| GPD (glyceraldehyde 3-phosphate dehydrogenase) family member (gpd-4) [Caenorhabditis elegans] sp\|P17331\|G3P4_CAEEL Glyceraldehyde-3-phosphate dehydrogenase 4 (GAPDH-4)	0.0
blast	CAA88870	Hypothetical protein T09F3.3 [Caenorhabditis elegans] emb\|CAA36900.1\| gpd-1 [Caenorhabditis elegans] emb\|CAA28504.1\| glyceraldehyde-3-phosphate dehydrogenase [Caenorhabditis elegans] ref\|NP_496237.1\| GPD (glyceraldehyde 3-phosphate dehydrogenase) family member (gpd-1) [Caenorhabditis elegans] sp\|P04970\|G3P1_CAEEL Glyceraldehyde-3-phosphate dehydrogenase 1 (GAPDH-1)	0.0
blast	CAE58358	Hypothetical protein CBG01479 [Caenorhabditis briggsae]	0.0

Protein Domains

Database	ID	Description	E-Value
Pfam	IPR000173 EMBL-EBI	Glyceraldehyde 3-phosphate dehydrogenase	4.6E-122
Pfam	IPR000173 EMBL-EBI	Glyceraldehyde 3-phosphate dehydrogenase	1.0E-126
Pfam	IPR000173 EMBL-EBI	Glyceraldehyde 3-phosphate dehydrogenase	9.6E-121

Sequence

Target Sequence

>C. ELEGANS:193860_S_AT
gtacgacgcttcgaatgatcacgttatttctaacgcatcgtgcaccaccaactgtctggc
accactggcgaaggttatcaatgataacttcggtatcatcgaaggactcatgacgacagt
gcacgctgtaaccgcaacccagaagacagtcgatggaccatccggaaagctgtggagaga
tggacgcggtgctggacaaaacatcattccagcttccactggagccgccaaggctgtggg
aaaagtcattccggagctgaacggaaagctcactggaatggctttccgtgtccctacacc
agatgtttccgtcgttgatctgaccgttcgcctcgagaaaccagcttcgatggatgacat
caagaaggtagtcaaggccgctgccgatggaccaatgaagggaatcctcgcctacaccga
agatcaagttgtgtcgactgacttcgtgtccgaccctcactcgtccattttcgatactgg
agcatgcatttcgctcaacccgaacttcgtcaagctcgtctcttggtacgacaatgaata
tggatactcgaaccgtgttgtc

BLASTn GenBank NR

Probe Info

Probe Sequence(5'-3')	Probe X	Probe Y	Probe Interrogation Position	Strandedness
GTACGACGCTTCGAATGATCACGTT	119	459	444	Antisense
CTGGCACCACTGGCGAAGGTTATCA	638	239	499	Antisense
GAAGGACTCATGACGACAGTGCACG	594	333	544	Antisense
TGACGACAGTGCACGCTGTAACCGC	61	571	554	Antisense
AACCGCAACCCAGAAGACAGTCGAT	315	145	573	Antisense
GGACCATCCGGAAAGCTGTGGAGAG	458	523	598	Antisense
GAGAGATGGACGCGGTGCTGGACAA	650	393	618	Antisense
AAAACATCATTCCAGCTTCCACTGG	298	131	641	Antisense
CACTGGAGCCGCCAAGGCTGTGGGA	275	199	660	Antisense
GAAAAGTCATTCCGGAGCTGAACGG	497	351	683	Antisense
ATATGGATACTCGAACCGTGTTGTC	255	21	981	Antisense

Sequence Source

Affymetrix Proprietary Database

Description	F33H1.2 /REP_DB=WormBase Gene ID /WP=CE01568 /GEN=gpd-4 /TR=SW:P17331 /GB=CAA88697.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=glyceraldehyde 3-phosphate dehydrogenase 4
Cluster	6grp_highest_10_10 > 88 6grp_high1_10_10 > 98 4grp_highest_8_8 > 04 4grp_high_8_8 > 38 6grp_highest_nonorm > 69 6grp_total > 98 4grp_total > 33 6grp_highest_sub > Da 6grp_cgc > 69 6grp_high1_sub > In 6grp_cgc_sub > Da 6grp_total_sub > Increase 6grp_rule_based > S6 4grp_rule_based > L2