[Home] | [Total List]

[193858_s_at]

Description F18H3.5A /REP_DB=WormBase Gene ID /WP=CE18608 /GEN=cdk-4 /TR=Q9XTB6 /GB=CAA90447.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=serine-threonine kinase (CDC2-CDKX subfamily)
Cluster 6grp_total > 11      4grp_total > 52      6grp_cgc > 44      6grp_cgc_sub > 02      6grp_total_sub > Hat      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 115
1 2 3 4 range
A 106.8
(-0.7)
A 		149.9
(3)
A 		115.6
(0)
A 		80.8
(-3)
A 		69
B 148.3
(2.7)
A 		153.4
(3)
A 		124.5
(1.5)
A 		38
(-3)
A 		115
C 152.1
(3)
A 		112.1
(-1.3)
A 		95.7
(-3)
A 		132
(0.9)
A 		56
avr 135.7
(2.7) 		138.5
(3) 		111.9
(0.1) 		83.6
(-3) 		55

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 129
1 2 3 4 5 6 range
A 92.3
(-0.9)
A 		126.4
(1.3)
A 		153.8
(3)
A 		94.7
(-0.7)
A 		70.9
(-2.2)
A 		58.4
(-3)
A 		95
B 128
(1.4)
A 		148.9
(3)
A 		146.9
(2.8)
A 		72.6
(-3)
A 		87.3
(-1.8)
A 		106.8
(-0.3)
A 		76
C 121.5
(-0.4)
A 		187.3
(3)
A 		84.9
(-2.3)
A 		70.9
(-3)
A 		93.4
(-1.8)
A 		105.2
(-1.2)
A 		116
avr 113.9
(-0.2) 		154.2
(3) 		128.5
(0.9) 		79.4
(-3) 		83.9
(-2.6) 		90.1
(-2.1) 		75
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 42
1 2 3 4 range
A 38.9
(3)
A 		32.5
(1.6)
A 		30.2
(1.1)
A 		11.8
(-3)
A 		27
B 47.3
(3)
A 		37.9
(1.6)
A 		28.8
(0.2)
A 		8.1
(-3)
A 		39
C 50.3
(3)
A 		32.2
(-0.9)
A 		33.4
(-0.6)
A 		22.3
(-3)
A 		28
avr 45.5
(3) 		34.2
(0.8) 		30.8
(0.2) 		14.1
(-3) 		31

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 43
1 2 3 4 5 6 range
A 17
(-2.5)
A 		45
(3)
A 		33.5
(0.8)
A 		24
(-1.1)
A 		21.4
(-1.6)
A 		14.2
(-3)
A 		31
B 44.5
(2)
A 		49.6
(3)
A 		35.7
(0.3)
A 		19.2
(-3)
A 		35.5
(0.2)
A 		39.8
(1.1)
A 		30
C 45
(1.3)
A 		57.2
(3)
A 		21.6
(-2)
A 		14.2
(-3)
A 		30.2
(-0.8)
A 		35.2
(-0.1)
A 		43
avr 35.5
(0.1) 		50.6
(3) 		30.3
(-0.9) 		19.1
(-3) 		29
(-1.1) 		29.7
(-1) 		32
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193858_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17455
Sequence Type Exemplar sequence
Representative Public ID F18H3.5A NCBI
Target Description F18H3.5A /REP_DB=WormBase Gene ID /WP=CE18608 /GEN=cdk-4 /TR=Q9XTB6 /GB=CAA90447.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=serine-threonine kinase (CDC2-CDKX subfamily)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077855(11), NM_001029420(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077855 NCBI Caenorhabditis elegans Cyclin-Dependent Kinase family member (cdk-4) (cdk-4) mRNA, complete cds. 11/11 A 
NM_001029420 NCBI Caenorhabditis elegans Cyclin-Dependent Kinase family member (cdk-4) (cdk-4) mRNA, complete cds. 11/11 None
SNAP00000033178 ENSEMBL cdna:SNAP chromosome:CEL140:X:13515970:13517270:-1 11/11 None
GENEFINDER00000033179 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:13515970:13517270:-1 11/11 None
F18H3.5a ENSEMBL cdna:known chromosome:CEL140:X:13515773:13518823:-1 gene:F18H3.5 11/11 A 
F18H3.5b ENSEMBL cdna:known chromosome:CEL140:X:13515970:13517673:-1 gene:F18H3.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:13515969-13518823(-) 100.0 100.0
Public Domain and Genome References
Ensembl F18H3.5
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast CAA90447 Hypothetical protein F18H3.5a [Caenorhabditis elegans] emb|CAB16925.1| Hypothetical protein F18H3.5a [Caenorhabditis elegans] ref|NP_510256.1| Cyclin-Dependent Kinase family member (cdk-4) [Caenorhabditis elegans] gb|AAD48898.1| cyclin-dependent kinase CDK-4 [Caenorhabditis elegans] 0.0
blast CAB16923 Hypothetical protein F18H3.5b [Caenorhabditis elegans] ref|NP_001024591.1| Cyclin-Dependent Kinase family member (cdk-4) [Caenorhabditis elegans] 0.0
blast CAB16923 Hypothetical protein F18H3.5b [Caenorhabditis elegans] ref|NP_001024591.1| Cyclin-Dependent Kinase family member (cdk-4) [Caenorhabditis elegans] 1.0E-172
blast CAA90447 Hypothetical protein F18H3.5a [Caenorhabditis elegans] emb|CAB16925.1| Hypothetical protein F18H3.5a [Caenorhabditis elegans] ref|NP_510256.1| Cyclin-Dependent Kinase family member (cdk-4) [Caenorhabditis elegans] gb|AAD48898.1| cyclin-dependent kinase CDK-4 [Caenorhabditis elegans] 1.0E-172
Protein Families
Method ID Description E-Value
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 1.0E-69
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 4.0E-70
ec A2S7_HUMAN (Q96Q40) Serine/threonine-protein kinase ALS2CR7 (EC 2.7.1.37) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene protein 7) 6.0E-70
hanks 3.1.4 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk4 1.0E-79
hanks 3.1.4 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk4 7.0E-80
hanks 3.1.4 CMCG Group; CMGC I Cyclin-dependent (CDKs) and close relatives; Cdk4 5.0E-80
Protein Domains
Database ID Description E-Value
Pfam IPR000719 EMBL-EBI Protein kinase 1.9E-88
Pfam IPR000719 EMBL-EBI Protein kinase 1.1E-84
Pfam IPR000719 EMBL-EBI Protein kinase 1.7E-84
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_001024591.1 1 76-98
F18H3.5b 1 76-98
Sequence
Target Sequence 
>C. ELEGANS:193858_S_AT
gcgcaatattccacgcggagttccggagcaacaagcaaaacatgtcactgcacaaattgt
tcgagcactggattttcttcacacacacagtatcattcatcgggatttgaagcctcagaa
tattctactcaacagagatcaaaccgtgaaattggctgattttggattgtcaaaagagta
ctcaaatacaacggctttcacaacattagttgtcactctttggtatcgatcaccggaagt
tcttcttcaatcctactacaacagtacagttgacatgtgggctctcgggtgcattgtatc
ggaaatttactgccgacagccactttttgtaggccaaaacgaggctgagcagttgacaga
cattttcaagaaaatgggcaccccagttggcaaggattggccgagtgaatctgtcatcgc
ccgagactcattcccacaatatcgcccgaccaacctcaaggatctgagcccgcagatgtc
aaaacaggcaatcgagtttgtgcaacagtgcctgagatatgatcattcgaagcgactttc
tgctcgtggagcattgagccatccgttcttgaagcctgcggtggca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCGCAATATTCCACGCGGAGTTCCG 598 287 414 Antisense
TCGAGCACTGGATTTTCTTCACACA 697 601 474 Antisense
AGTTCTTCTTCAATCCTACTACAAC 21 65 651 Antisense
GGCTCTCGGGTGCATTGTATCGGAA 10 539 693 Antisense
TTACTGCCGACAGCCACTTTTTGTA 76 675 720 Antisense
GGCACCCCAGTTGGCAAGGATTGGC 218 535 790 Antisense
TGGCCGAGTGAATCTGTCATCGCCC 259 545 811 Antisense
CCGAGACTCATTCCCACAATATCGC 672 263 834 Antisense
ACCAACCTCAAGGATCTGAGCCCGC 291 85 862 Antisense
TTCGAAGCGACTTTCTGCTCGTGGA 710 693 939 Antisense
TCCGTTCTTGAAGCCTGCGGTGGCA 667 593 975 Antisense
Sequence Source Affymetrix Proprietary Database