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[193810_at] G-protein coupled receptor (gastrin/cholecystokinin)

Description F59D12.1 /REP_DB=WormBase Gene ID /WP=CE11490 /TR=O17899 /GB=CAB04539.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=G-protein coupled receptor (gastrin-cholecystokinin)
Cluster 6grp_highest_10_10 > 60      6grp_high1_10_10 > 06      4grp_highest_8_8 > 59      4grp_high_8_8 > 25      6grp_highest_nonorm > 80      6grp_total > 06      4grp_total > 38      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 343
1 2 3 4 range
A 374.8
(3)
P 		123.1
(-3)
P 		136.2
(-2.7)
P 		167.6
(-1.9)
P 		252
B 331.3
(3)
P 		154.4
(-1)
P 		64.6
(-3)
P 		176
(-0.5)
P 		267
C 407.1
(3)
P 		199.5
(-1.6)
P 		135.2
(-3)
P 		185.2
(-1.9)
P 		272
avr 371.1
(3) 		159
(-1.9) 		112
(-3) 		176.3
(-1.5) 		259

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 332
1 2 3 4 5 6 range
A 313.7
(3)
P 		196.5
(-0.3)
P 		143.8
(-1.8)
P 		138.7
(-2)
P 		113.1
(-2.7)
P 		102.6
(-3)
P 		211
B 426
(3)
P 		213.3
(-0.8)
P 		174
(-1.6)
P 		164.6
(-1.7)
P 		136
(-2.2)
P 		93.9
(-3)
P 		332
C 335.6
(3)
P 		281.4
(1.5)
P 		177.1
(-1.3)
P 		118.3
(-3)
P 		116.9
(-3)
P 		121.6
(-2.9)
P 		219
avr 358.4
(3) 		230.4
(-0) 		165
(-1.6) 		140.5
(-2.2) 		122
(-2.6) 		106
(-3) 		252
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 121
1 2 3 4 range
A 136.4
(3)
P 		26.7
(-2.9)
P 		35.6
(-2.4)
P 		24.5
(-3)
P 		112
B 105.6
(3)
P 		38.1
(-1.5)
P 		15
(-3)
P 		37.5
(-1.5)
P 		91
C 134.8
(3)
P 		57.4
(-1.5)
P 		47.1
(-2.1)
P 		31.2
(-3)
P 		104
avr 125.6
(3) 		40.7
(-2.4) 		32.6
(-2.9) 		31.1
(-3) 		95

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 124
1 2 3 4 5 6 range
A 57.8
(1.4)
P 		69.9
(3)
P 		31.3
(-2.2)
P 		35.2
(-1.6)
P 		34.1
(-1.8)
P 		25
(-3)
P 		45
B 148.2
(3)
P 		71
(-1.1)
P 		42.3
(-2.6)
P 		43.6
(-2.5)
P 		55.2
(-1.9)
P 		35
(-3)
P 		113
C 124.4
(3)
P 		85.9
(0.7)
P 		45.1
(-1.7)
P 		23.8
(-3)
P 		37.8
(-2.2)
P 		40.7
(-2)
P 		101
avr 110.1
(3) 		75.6
(0.3) 		39.6
(-2.5) 		34.2
(-3) 		42.4
(-2.3) 		33.6
(-3) 		77
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193810_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.17548
Sequence Type Exemplar sequence
Representative Public ID F59D12.1 NCBI
Target Description F59D12.1 /REP_DB=WormBase Gene ID /WP=CE11490 /TR=O17899 /GB=CAB04539.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=G-protein coupled receptor (gastrin-cholecystokinin)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_078179(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_078179 NCBI Caenorhabditis elegans F59D12.1 (F59D12.1) mRNA, complete cds. 11/11 None
SNAP00000026819 ENSEMBL cdna:SNAP chromosome:CEL140:X:15670349:15671789:1 9/11 None
F59D12.1 ENSEMBL cdna:known chromosome:CEL140:X:15666679:15672281:1 gene:F59D12.1 11/11 A 
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
GENEFINDER00000026822 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:15667371-15671789(+) 100.0 100.0
Public Domain and Genome References
Gene Title G-protein coupled receptor (gastrin/cholecystokinin)
Ensembl F59D12.1
Entrez Gene 181656 Entrez gene
SwissProt O17899 EMBL-EBI
WormBase CE11490 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1637636_AT dm
DROSGENOME1:152630_AT dm
HG-U133_PLUS_2:221313_AT G protein-coupled receptor 52 hs
HG-U133A:221313_AT G protein-coupled receptor 52 hs
HG-FOCUS:221313_AT G protein-coupled receptor 52 hs
HG-U133A_2:221313_AT G protein-coupled receptor 52 hs
U133_X3P:G5031720_3P_AT G protein-coupled receptor 52 hs
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7186 G-protein coupled receptor protein signaling pathway inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
1584 rhodopsin-like receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB04539 Hypothetical protein F59D12.1 [Caenorhabditis elegans] ref|NP_510580.1| F59D12.1 [Caenorhabditis elegans] 1.0E-159
blast CAE63350 Hypothetical protein CBG07754 [Caenorhabditis briggsae] 1.0E-149
blast CAB04539 Hypothetical protein F59D12.1 [Caenorhabditis elegans] ref|NP_510580.1| F59D12.1 [Caenorhabditis elegans] 8.0E-66
blast CAE63350 Hypothetical protein CBG07754 [Caenorhabditis briggsae] 3.0E-60
blast CAH10219 G-protein coupled receptor [Drosophila melanogaster] gb|AAX52733.1| CG18314-PC, isoform C [Drosophila melanogaster] gb|AAX52732.1| CG18314-PB, isoform B [Drosophila melanogaster] gb|AAF47893.1| CG18314-PA, isoform A [Drosophila melanogaster] ref|NP_647897.2| CG18314-PA, isoform A [Drosophila melanogaster] ref|NP_001014560.1| CG18314-PB, isoform B [Drosophila melanogaster] ref|NP_001014559.1| CG18314-PC, isoform C [Drosophila melanogaster] 6.0E-37
Protein Domains
Database ID Description E-Value
Pfam IPR000276 EMBL-EBI Rhodopsin-like GPCR superfamily 7.5E-16
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510580.1 7 20-42,51-73,93-115,136-158,173-195,224-243,258-280
F59D12.1 7 20-42,51-73,93-115,136-158,173-195,224-243,258-280
SNAP00000026819 4 7-29,44-66,92-111,126-148
Sequence
Target Sequence 
>C. ELEGANS:193810_AT
taacttcaatgcttctatgctgcccaataattgttgcaagaatgcaggttgtgttctatc
ccgacgcgcagttatgtgtcctggactggtccgcaacatctgcatacagtgtgaccttac
tcctacttgtctttgtaccaactttagtaaccgtctttaacacaggctggaaaatctggt
cagctatgagaaatcctgcagcgcttgatgatagtcaaagaatgctcgtggaaacagacc
caaactttgtattaactggttttctgtttgtcacatttttcttgtcatggcttccattga
ttacattgaaggtgtgcgaattaatatggggcccatttgatatggatttatcaatgctca
cattcttcttcgtgtggttagcggtgtctggtccgtgttgcaagtttttgatctacatgt
tcacaaatcatcagttccgaaggtccttcctttcctacatttcatgctcaatgtgctgtt
cgagccggagtcg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TAACTTCAATGCTTCTATGCTGCCC 567 639 437 Antisense
GAATGCAGGTTGTGTTCTATCCCGA 613 327 476 Antisense
CCGACGCGCAGTTATGTGTCCTGGA 466 263 497 Antisense
CTGGTCCGCAACATCTGCATACAGT 416 241 522 Antisense
CATACAGTGTGACCTTACTCCTACT 651 211 539 Antisense
TACTCCTACTTGTCTTTGTACCAAC 270 647 554 Antisense
GTAACCGTCTTTAACACAGGCTGGA 176 463 583 Antisense
ATGCTCACATTCTTCTTCGTGTGGT 424 43 790 Antisense
AATCATCAGTTCCGAAGGTCCTTCC 658 169 862 Antisense
TTCCTTTCCTACATTTCATGCTCAA 594 699 883 Antisense
CAATGTGCTGTTCGAGCCGGAGTCG 703 167 905 Antisense
Sequence Source Affymetrix Proprietary Database