[Home] | [Total List]

[193805_at] female germline-specific tumor suppressor

Description T23G11.3 /REP_DB=WormBase Gene ID /WP=CE14096 /GEN=gld-1 /TR=Q17339 /GB=CAB03417.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=female germline-specific tumor suppressor
Cluster 6grp_total > 88      4grp_total > 50      6grp_cgc > 59      6grp_cgc_sub > Da      6grp_total_sub > Increase      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 79
1 2 3 4 range
A 61.6
(-3)
A 		97
(3)
A 		80.8
(0.3)
A 		83.8
(0.8)
P 		35
B 77.5
(-2)
M 		104.9
(3)
A 		89.4
(0.2)
P 		71.7
(-3)
P 		33
C 70.1
(-1)
A 		123.4
(3)
A 		107.6
(1.8)
P 		44.4
(-3)
A 		79
avr 69.7
(-2.6) 		108.4
(3) 		92.6
(0.7) 		66.6
(-3) 		42

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 236
1 2 3 4 5 6 range
A 49.5
(-3)
A 		78.1
(-2.2)
A 		61.5
(-2.7)
P 		71.9
(-2.4)
P 		187.3
(1)
P 		258.4
(3)
P 		209
B 85.7
(-1.9)
A 		95
(-1.6)
P 		56.9
(-3)
P 		91.5
(-1.7)
P 		141.9
(0.2)
P 		215.8
(3)
P 		159
C 50.4
(-2.2)
A 		103.8
(-0.7)
P 		22.9
(-3)
A 		92
(-1)
A 		146.9
(0.5)
P 		233.8
(3)
P 		211
avr 61.9
(-2.5) 		92.3
(-1.6) 		47.1
(-3) 		85.1
(-1.8) 		158.7
(0.5) 		236
(3) 		189
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 30
1 2 3 4 range
A 22.4
(3)
A 		21.1
(2.2)
A 		21.1
(2.2)
A 		12.3
(-3)
P 		10
B 24.7
(2.3)
M 		25.9
(3)
A 		20.7
(0.1)
P 		15.3
(-3)
P 		11
C 23.2
(0.1)
A 		35.5
(2.6)
A 		37.5
(3)
P 		7.5
(-3)
A 		30
avr 23.4
(1.4) 		27.5
(3) 		26.4
(2.6) 		11.7
(-3) 		16

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 75
1 2 3 4 5 6 range
A 9.1
(-3)
A 		27.8
(-0.9)
A 		13.4
(-2.5)
P 		18.2
(-2)
P 		56.5
(2.3)
P 		62.9
(3)
P 		54
B 29.8
(-1.6)
A 		31.6
(-1.4)
P 		13.8
(-3)
P 		24.2
(-2.1)
P 		57.7
(0.9)
P 		80.5
(3)
P 		67
C 18.7
(-1.9)
A 		31.7
(-0.9)
P 		5.8
(-3)
A 		18.5
(-1.9)
A 		47.5
(0.5)
P 		78.3
(3)
P 		73
avr 19.2
(-2.2) 		30.4
(-1.1) 		11
(-3) 		20.3
(-2.1) 		53.9
(1.1) 		73.9
(3) 		63
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193805_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.887
Sequence Type Exemplar sequence
Representative Public ID T23G11.3 NCBI
Target Description T23G11.3 /REP_DB=WormBase Gene ID /WP=CE14096 /GEN=gld-1 /TR=Q17339 /GB=CAB03417.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=female germline-specific tumor suppressor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059742(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059742 NCBI Caenorhabditis elegans defective in Germ Line Development family member (gld-1) (gld-1) mRNA, complete cds. 11/11 None
SNAP00000027650 ENSEMBL cdna:SNAP chromosome:CEL140:I:7703486:7705537:1 11/11 None
GENEFINDER00000027661 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:7703823:7705537:1 11/11 None
T23G11.3 ENSEMBL cdna:known chromosome:CEL140:I:7703808:7706333:1 gene:T23G11.3 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7703753-7705468(+) 100.0 100.0
Public Domain and Genome References
Gene Title female germline-specific tumor suppressor
Gene Symbol gld-1
Ensembl T23G11.3
Entrez Gene 172532 Entrez gene
SwissProt Q17339 EMBL-EBI
WormBase CE14096 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:14507_AT KH domain-containing protein at
ATH1-121501:266420_AT KH domain-containing protein at
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
3676 nucleic acid binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03417 Hypothetical protein T23G11.3 [Caenorhabditis elegans] ref|NP_492143.1| defective in Germ Line Development family member (gld-1) [Caenorhabditis elegans] sp|Q17339|GLD1_CAEEL Female germline-specific tumor suppressor gld-1 (Defective in germ line development protein 1) gb|AAC46632.1| female germline-specific tumor suppressor; similar to human GAP-associated tyrosine phosphoprotein p62, PIR Accession Number A38219, and C. elegans B0280.11 gene product encoded by GenBank Accession Number U10438 prf||2116296A tumor suppressor 0.0
blast CAE57359 Hypothetical protein CBG00303 [Caenorhabditis briggsae] 0.0
blast CAE67291 Hypothetical protein CBG12740 [Caenorhabditis briggsae] 3.0E-70
Protein Domains
Database ID Description E-Value
Pfam IPR004087 EMBL-EBI KH 7.6E-5
Pfam IPR004087 EMBL-EBI KH 7.6E-5
Sequence
Target Sequence 
>C. ELEGANS:193805_AT
tcattccggctcccgagggaactgacgagctgaagagaaaacaacttatggaacttgcaa
tcatcaacggtacgtatcgtccaatgaagtcgccaaacccagctcgtgtgatgactgcag
ttcctctgctctctccaactccactacgtagttcaggtccagttttgatgtcgccaactc
ctggatcaggactcccgtcaacgacatttggaggatcgatcttgagccccactctcactg
catccaaccttctcggatctaacgtcttcgattactcgcttctgagcccgagcatgtttg
attcattcagctctcttcaacttgcaagtgatttgacgttcccgaagtacccaacaacca
cttcgtttgtcaactcattccctggtcttttcacttctgcatcttcttttgccaatcaaa
caaacaccaatgtgtccccgagtggagcaagtcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TCATTCCGGCTCCCGAGGGAACTGA 650 615 917 Antisense
GTCCAATGAAGTCGCCAAACCCAGC 702 477 995 Antisense
CGTGTGATGACTGCAGTTCCTCTGC 273 245 1021 Antisense
TCTCCAACTCCACTACGTAGTTCAG 502 609 1048 Antisense
TTGGAGGATCGATCTTGAGCCCCAC 325 705 1124 Antisense
TGCATCCAACCTTCTCGGATCTAAC 301 579 1155 Antisense
CTAACGTCTTCGATTACTCGCTTCT 51 225 1175 Antisense
TTCATTCAGCTCTCTTCAACTTGCA 30 689 1218 Antisense
TGATTTGACGTTCCCGAAGTACCCA 243 561 1245 Antisense
AACCACTTCGTTTGTCAACTCATTC 518 147 1272 Antisense
ATGTGTCCCCGAGTGGAGCAAGTCC 296 49 1346 Antisense
Sequence Source Affymetrix Proprietary Database