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[193787_at] TATA binding protein associated factor

Description Y37E11B.4 /REP_DB=WormBase Gene ID /WP=CE19614 /GEN=taf-2 /TR=Q9TYN3 /GB=AAD12824.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=TATA binding protein associated factor
Cluster 6grp_total > 17      4grp_total > 22      6grp_cgc > 11      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 108
1 2 3 4 range
A 74.6
(3)
P 		23.9
(-3)
A 		24.1
(-3)
A 		53.1
(0.5)
A 		51
B 61.6
(2.9)
A 		62.1
(3)
A 		43.3
(0.4)
A 		19.5
(-3)
A 		43
C 53.4
(-0.4)
A 		7.3
(-3)
A 		25.3
(-2)
A 		115.5
(3)
A 		108
avr 63.2
(3) 		31.1
(-3) 		30.9
(-3) 		62.7
(2.9) 		32

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 69
1 2 3 4 5 6 range
A 68.5
(3)
A 		34.1
(-0.5)
A 		63.3
(2.5)
A 		9.7
(-3)
A 		42
(0.3)
A 		9.5
(-3)
A 		59
B 70.1
(3)
A 		15.5
(-2.1)
A 		24.7
(-1.2)
A 		5.5
(-3)
A 		12.2
(-2.4)
A 		33.1
(-0.4)
A 		65
C 74.8
(3)
P 		32.3
(-0.9)
A 		18.2
(-2.2)
A 		27.3
(-1.3)
A 		9.1
(-3)
A 		13.3
(-2.6)
A 		66
avr 71.1
(3) 		27.3
(-1.6) 		35.4
(-0.8) 		14.2
(-3) 		21.1
(-2.3) 		18.6
(-2.5) 		57
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 25
1 2 3 4 range
A 27.1
(3)
P 		5.2
(-3)
A 		6.3
(-2.7)
A 		7.8
(-2.3)
A 		22
B 19.7
(3)
A 		15.3
(1.3)
A 		10
(-0.8)
A 		4.2
(-3)
A 		16
C 17.7
(2.4)
A 		2.1
(-3)
A 		8.8
(-0.7)
A 		19.5
(3)
A 		17
avr 21.5
(3) 		7.5
(-3) 		8.4
(-2.6) 		10.5
(-1.7) 		14

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 26
1 2 3 4 5 6 range
A 12.6
(2.4)
A 		12.1
(2.1)
A 		13.8
(3)
A 		2.5
(-2.9)
A 		12.7
(2.4)
A 		2.3
(-3)
A 		12
B 24.4
(3)
A 		5.2
(-2)
A 		6
(-1.8)
A 		1.4
(-3)
A 		5
(-2.1)
A 		12.4
(-0.1)
A 		23
C 27.7
(3)
P 		9.9
(-1.3)
A 		4.6
(-2.6)
A 		5.5
(-2.4)
A 		2.9
(-3)
A 		4.5
(-2.6)
A 		25
avr 21.6
(3) 		9.1
(-1.1) 		8.1
(-1.4) 		3.1
(-3) 		6.9
(-1.8) 		6.4
(-1.9) 		19
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193787_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10987
Sequence Type Exemplar sequence
Representative Public ID Y37E11B.4 NCBI
Target Description Y37E11B.4 /REP_DB=WormBase Gene ID /WP=CE19614 /GEN=taf-2 /TR=Q9TYN3 /GB=AAD12824.1 /SUBMIT=ST.LOUIS /CHR=4 /FEA=Sanger Annotation /DEF=TATA binding protein associated factor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_067977(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_067977 NCBI Caenorhabditis elegans TAF (TBP-associated transcription factor) family member (taf-2) (taf-2) mRNA, complete cds. 11/11 None
SNAP00000044692 ENSEMBL cdna:SNAP chromosome:CEL140:IV:3581063:3593594:-1 9/11 None
GENEFINDER00000044703 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:3584730:3598541:-1 11/11 None
Y37E11B.4 ENSEMBL cdna:known chromosome:CEL140:IV:3584309:3593594:-1 gene:Y37E11B.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:3584735-3593600(-) 100.0 100.0
Public Domain and Genome References
Gene Title TATA binding protein associated factor
Gene Symbol taf-2
Ensembl Y37E11B.4
Entrez Gene 192051 Entrez gene
SwissProt Q9TYN3 EMBL-EBI
WormBase CE19614 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE:1589324_AT similar to TBP-associated factor 2 cfa
CANINE_2:CFAAFFX.2228.1.S1_AT similar to TBP-associated factor 2 cfa
CANINE_2:CFAAFFX.2228.1.S1_S_AT similar to TBP-associated factor 2 cfa
DROSOPHILA_2:1629974_AT TBP-associated factor 2 dm
DROSGENOME1:155034_AT TBP-associated factor 2 dm
CHICKEN:GGAAFFX.10509.1.S1_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa gga
CHICKEN:GGAAFFX.10509.2.S1_S_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa gga
CHICKEN:GGAAFFX.12938.1.S1_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa gga
CHICKEN:GGAAFFX.12938.1.S1_S_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa gga
HU35KSUBB:RC_R34694_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
U133_X3P:HS2.122752.2.S1_3P_S_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
U133_X3P:HS.122752.0.S2_3P_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
HG-U133_PLUS_2:1554721_A_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
HG-U133A_2:209523_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
HG-FOCUS:209523_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
HG-U133_PLUS_2:209523_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
HG-U133A:209523_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
HG-U95AV2:37770_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
HG-U95B:43916_I_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
HG-U95B:43917_R_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa hs
RAE230B:1392511_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor rn
RAT230_2:1392511_AT TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor rn
YEAST_2:1770535_AT TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4179 membrane alanyl aminopeptidase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast AAD12824 Taf (tbp-associated transcription factor) family protein 2 [Caenorhabditis elegans] ref|NP_500378.1| TAF (TBP-associated transcription factor) family member (taf-2) [Caenorhabditis elegans] 0.0
blast CAE63786 Hypothetical protein CBG08327 [Caenorhabditis briggsae] 0.0
blast AAD12825 Hypothetical protein Y37E11B.5 [Caenorhabditis elegans] ref|NP_500379.1| Y37E11B.5 [Caenorhabditis elegans] 0.0
blast CAE63785 Hypothetical protein CBG08326 [Caenorhabditis briggsae] 0.0
blast XP_393397 PREDICTED: similar to ENSANGP00000016472 [Apis mellifera] 1.0E-161
Protein Domains
Database ID Description E-Value
Pfam IPR001930 EMBL-EBI Peptidase M1, membrane alanine aminopeptidase 5.0E-6
Pfam IPR001269 EMBL-EBI Protein of unknown function UPF0034 1.5E-54
Pfam IPR001930 EMBL-EBI Peptidase M1, membrane alanine aminopeptidase 5.0E-6
Sequence
Target Sequence 
>C. ELEGANS:193787_AT
gctggactcgcaacttttgtggacattttcccatccgaactgttgtgttcaaatgcgacg
atgtgccattactctgatcattgatcggattgttaatgatccgcacgcggcggatactcg
gatgctcgacttgtcaaggatcctggagctcgccgagctggaacaagatccgtcgattcg
gagaatgattccgaggctgttggcgcaaactccgcccacaattttcggctcggaaaatgc
cgcgaacaccgctgaaactgcagaaagactatggaaactgtgcacaaattcgtcaattga
tagctgtattcggagtggttttctggatgtctactactctttatatgctctcggagcacc
accggctcttggtggacccgaggagtctgttggaattcatcgagcctacgtcacagtt

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GCTGGACTCGCAACTTTTGTGGACA 268 295 2739 Antisense
TTGTGGACATTTTCCCATCCGAACT 201 709 2755 Antisense
GACGATGTGCCATTACTCTGATCAT 377 379 2795 Antisense
GATACTCGGATGCTCGACTTGTCAA 63 425 2851 Antisense
CTTGTCAAGGATCCTGGAGCTCGCC 511 217 2868 Antisense
TGATTCCGAGGCTGTTGGCGCAAAC 286 563 2924 Antisense
TCCGCCCACAATTTTCGGCTCGGAA 285 597 2949 Antisense
AAAATGCCGCGAACACCGCTGAAAC 521 133 2972 Antisense
GTGGTTTTCTGGATGTCTACTACTC 575 489 3053 Antisense
CTACTACTCTTTATATGCTCTCGGA 293 227 3069 Antisense
AATTCATCGAGCCTACGTCACAGTT 111 177 3132 Antisense
Sequence Source Affymetrix Proprietary Database