[Home] | [Total List]

[193780_at] membrane-associated guanylate kinase homolog (MAGUK)

Description K01A6.2 /REP_DB=WormBase Gene ID /WP=CE06035 /TR=Q21074 /GB=CAA92964.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=membrane-associated guanylate kinase homolog (MAGUK)
Cluster 6grp_high1_10_10 > 20      4grp_high_8_8 > 61      6grp_total > 03      4grp_total > 51      6grp_cgc > 40      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 68
1 2 3 4 range
A 61.2
(-1.5)
A 		112.5
(3)
P 		51.7
(-2.4)
A 		44.5
(-3)
P 		68
B 79.1
(1)
P 		91.6
(3)
P 		87.8
(2.4)
A 		53.3
(-3)
A 		38
C 81.8
(-0.7)
A 		95.4
(1.5)
A 		104.8
(3)
P 		67.3
(-3)
M 		38
avr 74
(-0.5) 		99.8
(3) 		81.4
(0.5) 		55
(-3) 		45

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 87
1 2 3 4 5 6 range
A 69.7
(-3)
A 		90.6
(0.3)
P 		71.7
(-2.7)
P 		107.5
(3)
P 		73.1
(-2.5)
P 		75.4
(-2.1)
P 		38
B 83.7
(2.2)
P 		72.2
(1.2)
P 		20.8
(-3)
A 		94
(3)
A 		40.6
(-1.4)
P 		65.4
(0.7)
P 		73
C 84.8
(1.6)
P 		99.8
(2.7)
P 		103.8
(3)
P 		62.9
(-0.1)
A 		48.2
(-1.2)
P 		24.7
(-3)
A 		79
avr 79.4
(1.5) 		87.5
(2.9) 		65.4
(-1) 		88.1
(3) 		54
(-3) 		55.2
(-2.8) 		34
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 30
1 2 3 4 range
A 22.3
(2.3)
A 		24.4
(3)
P 		13.5
(-0.7)
A 		6.5
(-3)
P 		18
B 25.2
(3)
P 		22.6
(1.9)
P 		20.3
(0.9)
A 		11.4
(-3)
A 		14
C 27.1
(0.8)
A 		27.4
(0.8)
A 		36.5
(3)
P 		11.3
(-3)
M 		25
avr 24.9
(3) 		24.8
(3) 		23.4
(2.4) 		9.7
(-3) 		15

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 27
1 2 3 4 5 6 range
A 12.9
(-3)
A 		32.2
(3)
P 		15.6
(-2.2)
P 		27.3
(1.5)
P 		22.1
(-0.1)
P 		18.4
(-1.3)
P 		19
B 29.1
(3)
P 		24
(1.7)
P 		5
(-3)
A 		24.9
(2)
A 		16.5
(-0.1)
P 		24.4
(1.8)
P 		24
C 31.4
(3)
P 		30.4
(2.7)
P 		26.4
(1.7)
P 		12.7
(-1.9)
A 		15.6
(-1.1)
P 		8.3
(-3)
A 		23
avr 24.5
(1) 		28.9
(3) 		15.7
(-3) 		21.6
(-0.3) 		18.1
(-1.9) 		17
(-2.4) 		13
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193780_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9190
Sequence Type Exemplar sequence
Representative Public ID K01A6.2 NCBI
Target Description K01A6.2 /REP_DB=WormBase Gene ID /WP=CE06035 /TR=Q21074 /GB=CAA92964.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=membrane-associated guanylate kinase homolog (MAGUK)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069818(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069818 NCBI Caenorhabditis elegans K01A6.2 (K01A6.2) mRNA, complete cds. 11/11 None
SNAP00000040610 ENSEMBL cdna:SNAP chromosome:CEL140:IV:11715060:11716996:1 11/11 None
GENEFINDER00000040623 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:11706538:11728967:1 11/11 None
K01A6.2 ENSEMBL cdna:known chromosome:CEL140:IV:11713972:11729249:1 gene:K01A6.2 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11713977-11717002(+) 100.0 100.0
Public Domain and Genome References
Gene Title membrane-associated guanylate kinase homolog (MAGUK)
Gene Symbol magi-1
Ensembl K01A6.2
Entrez Gene 178107 Entrez gene
SwissProt Q21074 EMBL-EBI
WormBase CE37387 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.11008.1.S1_AT similar to Membrane associated guanylate kinase, WW and PDZ domain containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane associated guanylate kinase inverted-1) (MAGI-1) (Atrophin-1 interacting protein 3) (AIP3) (WW domain-containing p... cfa
CANINE_2:CFAAFFX.11008.1.S1_S_AT similar to Membrane associated guanylate kinase, WW and PDZ domain containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane associated guanylate kinase inverted-1) (MAGI-1) (Atrophin-1 interacting protein 3) (AIP3) (WW domain-containing p... cfa
CANINE_2:CFAAFFX.11023.1.S1_S_AT similar to Membrane associated guanylate kinase, WW and PDZ domain containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane associated guanylate kinase inverted-1) (MAGI-1) (Atrophin-1 interacting protein 3) (AIP3) (WW domain-containing p... cfa
CANINE_2:CFAAFFX.11033.1.S1_AT similar to Membrane associated guanylate kinase, WW and PDZ domain containing protein 1 (BAI1-associated protein 1) (BAP-1) (Membrane associated guanylate kinase inverted-1) (MAGI-1) (Atrophin-1 interacting protein 3) (AIP3) (WW domain-containing p... cfa
CHICKEN:GGA.2195.1.S1_AT similar to MAGI1c alpha beta2 gamma gga
CHICKEN:GGAAFFX.4634.1.S1_AT similar to MAGI1c alpha beta2 gamma gga
CHICKEN:GGAAFFX.4634.2.S1_S_AT similar to MAGI1c alpha beta2 gamma gga
CHICKEN:GGAAFFX.4634.4.S1_AT similar to MAGI1c alpha beta2 gamma gga
HG-U133_PLUS_2:232859_S_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133B:232859_S_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95AV2:32268_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95AV2:32269_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95AV2:150_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HC-G110:150_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133_PLUS_2:206144_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133A:206144_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-FOCUS:206144_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133A_2:206144_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HU35KSUBA:RC_AA026617_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HU35KSUBA:HUM_ALU_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HU35KSUBB:HUM_ALU_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HU35KSUBC:HUM_ALU_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HU35KSUBD:HUM_ALU_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HUGENEFL:HUM_ALU_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HC-G110:HUM_ALU_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HU35KSUBD:RC_AA621788_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HUGENEFL:U96115_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
U133_X3P:G9257194_3P_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
U133_X3P:HS2.157093.1.A1_3P_S_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
U133_X3P:HS2.157093.1.A1_3P_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
U133_X3P:HS2.169441.3.S1_3P_S_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
U133_X3P:HS.21610.1.S1_3P_A_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
U133_X3P:HS.21610.0.S2_3P_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
U133_X3P:HS.21610.0.S1_3P_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133_PLUS_2:1555262_A_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133_PLUS_2:1559256_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133_PLUS_2:1559257_A_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133_PLUS_2:225465_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133B:225465_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133_PLUS_2:225474_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133B:225474_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95AV2:32270_G_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95B:58218_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95C:63817_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95E:67248_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95D:81395_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95D:83698_R_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
U133_X3P:HS.287475.0.S1_3P_X_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
U133_X3P:215372_3P_X_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133A_2:215372_X_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133_PLUS_2:215372_X_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133A:215372_X_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133_PLUS_2:1566538_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133_PLUS_2:1566539_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133A_2:222372_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133_PLUS_2:222372_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U133A:222372_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95B:43227_R_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95C:49850_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95C:53325_R_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95C:66124_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95D:68061_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95D:68074_R_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HG-U95D:76773_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HU35KSUBB:RC_AA015985_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HU35KSUBB:RC_AA076238_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
HU35KSUBC:RC_AA486073_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
U133_X3P:HS.291289.0.A1_3P_AT Membrane associated guanylate kinase, WW and PDZ domain containing 1 hs
MOE430A:1451893_S_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOUSE430A_2:1451893_S_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOUSE430_2:1451893_S_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOE430A:1427246_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOUSE430A_2:1427246_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOUSE430_2:1427246_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MG-U74CV2:136595_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOE430A:1452369_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOUSE430A_2:1452369_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOUSE430_2:1452369_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOE430B:1440871_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOUSE430_2:1440871_AT membrane associated guanylate kinase, WW and PDZ domain containing 1 mm
MOUSE430_2:1458240_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOE430B:1458240_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOE430B:1440071_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOUSE430_2:1440071_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOUSE430_2:1443231_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOE430B:1443231_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOE430B:1445088_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOUSE430_2:1445088_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOE430B:1445952_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOUSE430_2:1445952_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOE430B:1446050_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOUSE430_2:1446050_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOE430B:1457572_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MOUSE430_2:1457572_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
MU19KSUBC:TC35581_AT Putative membrane-associated guanylate kinase 1 (Magi-1) mRNA, alternatively spliced c form mm
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5515 protein binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92964 Hypothetical protein K01A6.2 [Caenorhabditis elegans] ref|NP_502219.2| K01A6.2 [Caenorhabditis elegans] 0.0
blast T23160 hypothetical protein K01A6.1 - Caenorhabditis elegans 0.0
blast CAE62065 Hypothetical protein CBG06086 [Caenorhabditis briggsae] 0.0
blast CAA92964 Hypothetical protein K01A6.2 [Caenorhabditis elegans] ref|NP_502219.2| K01A6.2 [Caenorhabditis elegans] 3.0E-93
Protein Domains
Database ID Description E-Value
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 9.7E-8
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 7.2E-16
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 8.0E-15
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 5.7E-22
Pfam IPR001202 EMBL-EBI WW/Rsp5/WWP domain 1.2E-13
Pfam IPR001202 EMBL-EBI WW/Rsp5/WWP domain 1.3E-11
Pfam IPR008144 EMBL-EBI Guanylate kinase 2.4E-15
Pfam IPR008144 EMBL-EBI Guanylate kinase 5.8E-13
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 9.7E-8
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 7.2E-16
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 8.0E-15
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 5.7E-22
Pfam IPR001202 EMBL-EBI WW/Rsp5/WWP domain 1.2E-13
Pfam IPR008144 EMBL-EBI Guanylate kinase 2.4E-15
Pfam IPR003165 EMBL-EBI Stem cell self-renewal protein Piwi 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:193780_AT
agcacttcactagattccactgacaaactgccatccggacttgctgctcgtcgactgatc
cgtattgccagtgaacatcatcatatttccacgacatcttcttgccattcggactctgga
aactcttcatctcgagacgtcatcaccccgtttacagtacatggcggagcctcaattgga
cgactcattctgattgatattgtgcgacgtgatgatttaattggaattgttcatcctaac
gatattcttttaacaattgagaacataaaagtatcaggaatggtaagatctgaagtgaat
aggatattggaagatatgatgagagaacatgatcaaattgcgattgaaattctaccagct
ggagcaattaccgatgatatttgtgaactactggccgatagaaaatcatctggtgaactt
cagactatcattcgagaaaatttatatcagaagacagttccttacacaactcgacctcca
cgagaaggtgaagttgatggagaacactatcgatttgtgtctgtagatgattttaataag
cttctcgacagtggtgacttgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AGCACTTCACTAGATTCCACTGACA 466 77 250 Antisense
TCCACTGACAAACTGCCATCCGGAC 412 589 265 Antisense
GTCGACTGATCCGTATTGCCAGTGA 218 475 299 Antisense
ACATCATCATATTTCCACGACATCT 158 107 324 Antisense
GCCATTCGGACTCTGGAAACTCTTC 588 279 353 Antisense
GAAACTCTTCATCTCGAGACGTCAT 164 357 368 Antisense
TCATCACCCCGTTTACAGTACATGG 167 619 389 Antisense
AGCCTCAATTGGACGACTCATTCTG 398 83 417 Antisense
AAGACAGTTCCTTACACAACTCGAC 467 151 700 Antisense
CACAACTCGACCTCCACGAGAAGGT 78 189 714 Antisense
AAGCTTCTCGACAGTGGTGACTTGC 425 149 787 Antisense
Sequence Source Affymetrix Proprietary Database