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[193775_at] cyclin A/CDK2-associated protein P19 like

Description F46A9.4 /REP_DB=WormBase Gene ID /WP=CE10578 /GEN=skr-2 /TR=Q93731 /GB=CAB03108.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cyclin A-CDK2-associated protein P19 like
Cluster 6grp_highest_10_10 > 79      6grp_high1_10_10 > 96      4grp_highest_8_8 > 14      4grp_high_8_8 > 15      6grp_highest_nonorm > 99      6grp_total > 96      4grp_total > 08      6grp_highest_sub > In      6grp_cgc > 68      6grp_high1_sub > In      6grp_cgc_sub > In      6grp_total_sub > Increase      6grp_rule_based > S6      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1221
1 2 3 4 range
A 204.3
(-3)
P
355.7
(-1.9)
P
508.6
(-0.9)
P
1056.4
(3)
P
852
B 229
(-3)
P
361.9
(-2.3)
P
597.9
(-1.1)
P
1425
(3)
P
1196
C 240.2
(-3)
P
326.4
(-2.5)
P
502.5
(-1.5)
P
1283.1
(3)
P
1043
avr 224.5
(-3)
348
(-2.3)
536.3
(-1.2)
1254.8
(3)
1030

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2213
1 2 3 4 5 6 range
A 202.1
(-3)
P
274.2
(-2.8)
P
493.1
(-2.1)
P
958.1
(-0.7)
P
1194.1
(0)
P
2158.2
(3)
P
1956
B 174.9
(-3)
P
283.4
(-2.6)
P
482.1
(-1.9)
P
628.5
(-1.4)
P
1107.9
(0.3)
P
1880.2
(3)
P
1705
C 191.6
(-3)
P
265
(-2.8)
P
542
(-2)
P
875.8
(-1.1)
P
1683.6
(1.1)
P
2387.6
(3)
P
2196
avr 189.5
(-3)
274.2
(-2.7)
505.7
(-2)
820.8
(-1.1)
1328.5
(0.5)
2142
(3)
1953
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 231
1 2 3 4 range
A 74.4
(-3)
P
77.2
(-2.8)
P
133
(1.4)
P
154.6
(3)
P
80
B 73
(-3)
P
89.4
(-2.6)
P
138.5
(-1.3)
P
303.7
(3)
P
231
C 79.5
(-3)
P
93.8
(-2.4)
P
175.2
(1.2)
P
216.4
(3)
P
137
avr 75.6
(-3)
86.8
(-2.5)
148.9
(-0.1)
224.9
(3)
149

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 762
1 2 3 4 5 6 range
A 37.2
(-3)
P
97.5
(-2.3)
P
107.4
(-2.1)
P
243
(-0.5)
P
360.3
(1)
P
525.5
(3)
P
488
B 60.9
(-3)
P
94.3
(-2.7)
P
117.1
(-2.5)
P
166.5
(-2)
P
450.1
(0.6)
P
701.1
(3)
P
640
C 71
(-3)
P
80.9
(-2.9)
P
138
(-2.4)
P
176.1
(-2.1)
P
544.8
(0.9)
P
799.3
(3)
P
728
avr 56.4
(-3)
90.9
(-2.7)
120.8
(-2.4)
195.2
(-1.7)
451.7
(0.8)
675.3
(3)
619
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193775_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.878
Sequence Type Exemplar sequence
Representative Public ID F46A9.4 NCBI
Target Description F46A9.4 /REP_DB=WormBase Gene ID /WP=CE10578 /GEN=skr-2 /TR=Q93731 /GB=CAB03108.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=cyclin A-CDK2-associated protein P19 like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060111(11)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_060111 NCBI Caenorhabditis elegans SKp1 Related (ubiquitin ligase complex component) family member (skr-2) (skr-2) mRNA, complete cds. 11/11 None
SNAP00000008778 ENSEMBL cdna:SNAP chromosome:CEL140:I:9477827:9478577:1 11/11 None
GENEFINDER00000008780 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:9477827:9478577:1 11/11 None
F46A9.4 ENSEMBL cdna:known chromosome:CEL140:I:9477813:9478756:1 gene:F46A9.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:9477757-9478508(+) 100.0 100.0
Public Domain and Genome References
Gene Title cyclin A/CDK2-associated protein P19 like
Gene Symbol skr-2
Ensembl F46A9.4
Entrez Gene 172773 Entrez gene
SwissProt Q93731 EMBL-EBI
WormBase CE10578 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:20416_S_AT E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 (At11), putative at
ATH1-121501:253271_S_AT E3 ubiquitin ligase SCF complex subunit SKP1/ASK1 (At11), putative at
Gene Ontology
GO Cellular Component (view graph)
ID Description Evidence Links
19005 SCF ubiquitin ligase complex inferred from physical interaction QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03108 Hypothetical protein F46A9.4 [Caenorhabditis elegans] ref|NP_492512.1| SKp1 Related (ubiquitin ligase complex component) family member (skr-2) [Caenorhabditis elegans] gb|AAL34094.1| SKR-2 [Caenorhabditis elegans] 1.0E-88
blast CAB03110 Hypothetical protein F46A9.5 [Caenorhabditis elegans] emb|CAB03027.1| Hypothetical protein F46A9.5 [Caenorhabditis elegans] ref|NP_492513.1| SKp1 Related (ubiquitin ligase complex component) family member (skr-1) [Caenorhabditis elegans] 3.0E-70
blast AAL34093 SKR-1 [Caenorhabditis elegans] 4.0E-67
Protein Domains
Database ID Description E-Value
Pfam IPR001232 EMBL-EBI SKP1 component 4.4E-51
Pfam IPR001232 EMBL-EBI SKP1 component 1.2E-31
Sequence
Target Sequence
>C. ELEGANS:193775_AT
gcatccgaagcagcaaagaaccgcgaaatcaagatctcgtcttcggatgatgaaatcttc
ttggtcccacgcaatgtgatccgtctctcaaacactctcaacactcttcttgtggacctc
gggctcgacgacgatgaaggaaccaacgctgagccaattccagtgcaaaacgtcactgcc
tcgattttgaagaaggttatcaactggtgcaccaaacaccagtccgacccaattccaact
gaagacagtgagaagaaaacggatggttccatccaagactgggacaaaaaatttctcgat
attgaccaaggaacccttttcgagctcattttggctgccaactatttggacatcaaagga
cttcttgatgtcgcctgccagtctgtcgccaacatgatcaagggaaaatctccagatgaa
attcgtcgtgctttcaacatcaaggacgacttcactgcagaggag


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
GCATCCGAAGCAGCAAAGAACCGCG 201 309 31 Antisense
GAACCGCGAAATCAAGATCTCGTCT 27 347 48 Antisense
GATCTCGTCTTCGGATGATGAAATC 42 419 63 Antisense
CACTCTCAACACTCTTCTTGTGGAC 99 197 123 Antisense
GAAGGTTATCAACTGGTGCACCAAA 687 333 222 Antisense
GTCCGACCCAATTCCAACTGAAGAC 657 475 252 Antisense
GATGGTTCCATCCAAGACTGGGACA 202 407 292 Antisense
CAAAGGACTTCTTGATGTCGCCTGC 195 193 384 Antisense
CCAGTCTGTCGCCAACATGATCAAG 628 271 408 Antisense
TTCGTCGTGCTTTCAACATCAAGGA 17 697 452 Antisense
CAAGGACGACTTCACTGCAGAGGAG 287 183 471 Antisense
Sequence Source Affymetrix Proprietary Database