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[193755_s_at] protein disulphide isomerase ER-60 precursor like

Description H06O01.1 /REP_DB=WormBase Gene ID /WP=CE11570 /TR=O17908 /GB=CAB07480.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=protein disulphide isomerase ER-60 precursor like
Cluster 6grp_highest_10_10 > 21      6grp_high1_10_10 > 01      4grp_highest_8_8 > 13      4grp_high_8_8 > 30      6grp_highest_nonorm > 17      6grp_total > 23      4grp_total > 24      6grp_highest_sub > De      6grp_cgc > 31      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 10622
1 2 3 4 range
A 10343.8
(-3)
P 		14698.7
(-0.3)
P 		15424.7
(0.2)
P 		19911
(3)
P 		9567
B 10019.5
(-3)
P 		12655.3
(-0.4)
P 		15364.6
(2.2)
P 		16174.8
(3)
P 		6155
C 9289.3
(-3)
P 		13318.3
(0.6)
P 		13054
(0.3)
P 		16097
(3)
P 		6808
avr 9884.2
(-3) 		13557.4
(-0.1) 		14614.4
(0.8) 		17394.3
(3) 		7510

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 6391
1 2 3 4 5 6 range
A 13729.7
(3)
P 		11544.9
(0.2)
P 		9757.1
(-2.1)
P 		10442.9
(-1.2)
P 		9049.5
(-3)
P 		9656.5
(-2.2)
P 		4680
B 11792
(3)
P 		10636
(1.4)
P 		11740.4
(2.9)
P 		10191.3
(0.8)
P 		8628.3
(-1.3)
P 		7338.3
(-3)
P 		4454
C 11927.3
(3)
P 		11111.5
(1.9)
P 		11636.3
(2.6)
P 		10195.7
(0.7)
P 		9998
(0.4)
P 		7388.8
(-3)
P 		4539
avr 12483
(3) 		11097.5
(1.1) 		11044.6
(1) 		10276.6
(-0) 		9225.3
(-1.5) 		8127.9
(-3) 		4355
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1836
1 2 3 4 range
A 3766.2
(1.6)
P 		3190.7
(-1.5)
P 		4032.3
(3)
P 		2914.6
(-3)
P 		1118
B 3195.2
(-2)
P 		3125.6
(-3)
P 		3560.3
(3)
P 		3446.9
(1.4)
P 		435
C 3075
(-1.8)
P 		3829.1
(0.6)
P 		4549.7
(3)
P 		2714.2
(-3)
P 		1836
avr 3345.5
(-1.1) 		3381.8
(-0.9) 		4047.4
(3) 		3025.2
(-3) 		1022

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2371
1 2 3 4 5 6 range
A 2531
(-1.8)
P 		4106
(3)
P 		2124.9
(-3)
P 		2648.6
(-1.4)
P 		2730.7
(-1.2)
P 		2351.1
(-2.3)
P 		1981
B 4103
(3)
P 		3540.3
(0.6)
P 		2850.9
(-2.4)
P 		2699.3
(-3)
P 		3505.6
(0.4)
P 		2736.4
(-2.8)
P 		1404
C 4420.9
(3)
P 		3390.5
(0.4)
P 		2961.6
(-0.7)
P 		2050.4
(-3)
P 		3235.2
(-0)
P 		2473.5
(-1.9)
P 		2371
avr 3685
(3) 		3678.9
(3) 		2645.8
(-2.1) 		2466.1
(-3) 		3157.2
(0.4) 		2520.3
(-2.7) 		1219
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193755_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2016
Sequence Type Exemplar sequence
Representative Public ID H06O01.1 NCBI
Target Description H06O01.1 /REP_DB=WormBase Gene ID /WP=CE11570 /TR=O17908 /GB=CAB07480.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=protein disulphide isomerase ER-60 precursor like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059594(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059594 NCBI Caenorhabditis elegans Protein Disulfide Isomerase family member (pdi-3) (pdi-3) mRNA, complete cds. 11/11 None
SNAP00000021145 ENSEMBL cdna:SNAP chromosome:CEL140:I:7024269:7026906:-1 11/11 None
H06O01.1.3 ENSEMBL cdna:known chromosome:CEL140:I:7023595:7028922:-1 gene:H06O01.1 11/11 None
H06O01.1.2 ENSEMBL cdna:known chromosome:CEL140:I:7024040:7028932:-1 gene:H06O01.1 11/11 None
H06O01.1.1 ENSEMBL cdna:known chromosome:CEL140:I:7024040:7028922:-1 gene:H06O01.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:7024199-7028850(-) 100.0 100.0
Public Domain and Genome References
Gene Title protein disulphide isomerase ER-60 precursor like
Gene Symbol pdi-3
Ensembl H06O01.1
Entrez Gene 172433 Entrez gene
SwissProt O17908 EMBL-EBI
WormBase CE11570 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:259757_AT protein disulfide isomerase, putative at
CANINE:1589034_AT similar to protein disulfide isomerase-associated 3 precursor cfa
CANINE_2:CFA.15120.1.S1_S_AT similar to protein disulfide isomerase-associated 3 precursor cfa
CANINE_2:CFA.21639.1.S1_S_AT similar to protein disulfide isomerase-associated 3 precursor cfa
DROSOPHILA_2:1631379_A_AT dm
DROSGENOME1:152545_AT dm
CHICKEN:GGA.3802.1.S1_S_AT protein disulfide isomerase family A, member 3 gga
CHICKEN:GGA.3802.2.S1_A_AT protein disulfide isomerase family A, member 3 gga
CHICKEN:GGAAFFX.22540.1.A1_AT protein disulfide isomerase family A, member 3 gga
HG-U133_PLUS_2:208612_AT protein disulfide isomerase family A, member 3 hs
HG-U133A:208612_AT protein disulfide isomerase family A, member 3 hs
HG-FOCUS:208612_AT protein disulfide isomerase family A, member 3 hs
HG-U133A_2:208612_AT protein disulfide isomerase family A, member 3 hs
HU35KSUBB:RC_AA115310_AT protein disulfide isomerase family A, member 3 hs
HU35KSUBC:RC_AA026318_S_AT protein disulfide isomerase family A, member 3 hs
HU35KSUBD:RC_AA478521_AT protein disulfide isomerase family A, member 3 hs
HUGENEFL:Z49835_S_AT protein disulfide isomerase family A, member 3 hs
U133_X3P:G1208426_3P_AT protein disulfide isomerase family A, member 3 hs
U133_X3P:HS.289101.1.A1_3P_AT protein disulfide isomerase family A, member 3 hs
HG-U133_PLUS_2:227033_AT protein disulfide isomerase family A, member 3 hs
HG-U133B:227033_AT protein disulfide isomerase family A, member 3 hs
HG-U95AV2:38986_AT protein disulfide isomerase family A, member 3 hs
HG-U95B:48098_AT protein disulfide isomerase family A, member 3 hs
HG-U95D:74821_S_AT protein disulfide isomerase family A, member 3 hs
HG-U95C:63529_AT Protein disulfide isomerase family A, member 3 hs
MOE430A:1423423_AT protein disulfide isomerase associated 3 mm
MOUSE430A_2:1423423_AT protein disulfide isomerase associated 3 mm
MOUSE430_2:1423423_AT protein disulfide isomerase associated 3 mm
MOUSE430_2:1445330_AT protein disulfide isomerase associated 3 mm
MOE430B:1445330_AT protein disulfide isomerase associated 3 mm
MU11KSUBA:M73329_S_AT protein disulfide isomerase associated 3 mm
MG-U74AV2:101060_AT protein disulfide isomerase associated 3 mm
MU19KSUBC:TC36787_AT Protein disulfide isomerase associated 3, mRNA (cDNA clone MGC:28333 IMAGE:4016310) mm
RT-U34:X12355_S_AT glucose regulated protein, 58 kDa rn
RG-U34A:X12355_S_AT glucose regulated protein, 58 kDa rn
RAE230A:1398788_AT glucose regulated protein, 58 kDa rn
RAT230_2:1398788_AT glucose regulated protein, 58 kDa rn
RAE230A:1375388_AT Glucose regulated protein, 58 kDa rn
RAT230_2:1375388_AT Glucose regulated protein, 58 kDa rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6118 electron transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
5783 endoplasmic reticulum inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5489 electron transporter activity inferred from electronic annotation QuickGO AmiGO
16853 isomerase activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB07480 Hypothetical protein H06O01.1 [Caenorhabditis elegans] ref|NP_491995.1| Protein Disulfide Isomerase family member (pdi-3) [Caenorhabditis elegans] dbj|BAB88817.1| ceERp57 [Caenorhabditis elegans] 0.0
blast CAE65710 Hypothetical protein CBG10789 [Caenorhabditis briggsae] 0.0
blast CAD29445 protein disulfide isomerase 1 [Ostertagia ostertagi] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 7.8E-18
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 6.7E-46
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 3.8E-49
Pfam IPR006662 EMBL-EBI Thioredoxin type domain 6.7E-46
Sequence
Target Sequence 
>C. ELEGANS:193755_S_AT
ttcaattcgccgtttccaacaaagaagaattctcttctgaaattgaaaccaatggactag
gagagcgcaaggactcggataagccaatcgttgccattctcactaatgaaggaaagtatc
caatggaccaagaattcagcgttgacaatctccagcaattcgttgatgaagttctcgccg
gaaatgccgaaccatacatgaagtctgagccaatcccagatgaacaaggagacgttaagg
ttgccgttggaaagaacttcaaggaacttatcatggatgctgataaggatgtgctcattg
aattttatgctccatggtgcggacattgcaaatcattggctccaaaatacgaggaacttg
ctgagaagctcaacaaggaagatgttatcattgctaagatggatgccaccgccaatgatg
ttccaccaatgttcgaagttagaggattcccaactctcttctggcttccaaagaacgcta
agtcgaacccgatcccatacaatggaggacgcgaagttaaggatttcgtcagcttcatct
caaagcactctactgat

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCAATTCGCCGTTTCCAACAAAGA 244 685 869 Antisense
GAGAGCGCAAGGACTCGGATAAGCC 349 395 929 Antisense
GATAAGCCAATCGTTGCCATTCTCA 223 423 946 Antisense
GAATTCAGCGTTGACAATCTCCAGC 316 325 1000 Antisense
GACAATCTCCAGCAATTCGTTGATG 476 363 1012 Antisense
GATGAAGTTCTCGCCGGAAATGCCG 221 411 1033 Antisense
ATACATGAAGTCTGAGCCAATCCCA 29 23 1062 Antisense
GGACATTGCAAATCATTGGCTCCAA 249 525 1189 Antisense
TGCTAAGATGGATGCCACCGCCAAT 253 579 1260 Antisense
TCGAACCCGATCCCATACAATGGAG 331 601 1351 Antisense
CTTCATCTCAAAGCACTCTACTGAT 516 221 1401 Antisense
Sequence Source Affymetrix Proprietary Database