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[193744_s_at] ATP-binding protein (AAA protein family member)

Description M03C11.5 /REP_DB=WormBase Gene ID /WP=CE03496 /TR=SW:P54813 /GB=CAA88955.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=ATP-binding protein (AAA protein family member)
Cluster 6grp_highest_10_10 > 71      6grp_high1_10_10 > 28      4grp_highest_8_8 > 55      4grp_high_8_8 > 10      6grp_highest_nonorm > 71      6grp_total > 17      4grp_total > 21      6grp_highest_sub > De      6grp_high1_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 155
1 2 3 4 range
A 386.7
(1.1)
P 		383.6
(1)
P 		292
(-3)
P 		429.1
(3)
P 		137
B 389.6
(3)
P 		297.6
(-3)
P 		350.6
(0.5)
P 		348.4
(0.3)
P 		92
C 350.5
(0.9)
P 		312.7
(-1)
P 		274.1
(-3)
P 		391.8
(3)
P 		118
avr 375.6
(2) 		331.3
(-1.2) 		305.6
(-3) 		389.8
(3) 		84

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 340
1 2 3 4 5 6 range
A 348.1
(2.3)
P 		368
(3)
P 		192.9
(-3)
P 		330.6
(1.7)
P 		283.2
(0.1)
P 		364.3
(2.9)
P 		175
B 334.5
(3)
P 		260.2
(-1.4)
P 		309.1
(1.5)
P 		232.4
(-3)
P 		290.7
(0.4)
P 		233.1
(-3)
P 		102
C 532.6
(3)
P 		348.3
(-1.3)
P 		392.2
(-0.3)
P 		276.4
(-3)
P 		351.3
(-1.2)
P 		310.6
(-2.2)
P 		256
avr 405.1
(3) 		325.5
(-0.8) 		298.1
(-2.1) 		279.8
(-3) 		308.4
(-1.6) 		302.7
(-1.9) 		125
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 78
1 2 3 4 range
A 140.8
(3)
P 		83.3
(-1.4)
P 		76.3
(-2)
P 		62.8
(-3)
P 		78
B 124.2
(3)
P 		73.5
(-3)
P 		81.2
(-2.1)
P 		74.3
(-2.9)
P 		51
C 116
(3)
P 		89.9
(-0.1)
P 		95.5
(0.5)
P 		66.1
(-3)
P 		50
avr 127
(3) 		82.2
(-1.5) 		84.3
(-1.3) 		67.7
(-3) 		59

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 155
1 2 3 4 5 6 range
A 64.2
(-1.5)
P 		130.9
(3)
P 		42
(-3)
P 		83.8
(-0.2)
P 		85.4
(-0.1)
P 		88.7
(0.2)
P 		89
B 116.4
(2.8)
P 		86.6
(-0.3)
P 		75.1
(-1.6)
P 		61.6
(-3)
P 		118.1
(3)
P 		86.9
(-0.3)
P 		57
C 197.4
(3)
P 		106.3
(-0.9)
P 		99.8
(-1.1)
P 		55.6
(-3)
P 		113.7
(-0.5)
P 		104
(-1)
P 		142
avr 126
(3) 		107.9
(1.2) 		72.3
(-2.5) 		67
(-3) 		105.7
(0.9) 		93.2
(-0.3) 		59
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193744_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.6971
Sequence Type Exemplar sequence
Representative Public ID M03C11.5 NCBI
Target Description M03C11.5 /REP_DB=WormBase Gene ID /WP=CE03496 /TR=SW:P54813 /GB=CAA88955.1 /SUBMIT=HINXTON /CHR=3 /FEA=Sanger Annotation /DEF=ATP-binding protein (AAA protein family member)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_066897(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_066897 NCBI Caenorhabditis elegans M03C11.5 (M03C11.5) mRNA, complete cds. 11/11 None
SNAP00000000518 ENSEMBL cdna:SNAP chromosome:CEL140:III:10416034:10421240:1 11/11 None
GENEFINDER00000000559 ENSEMBL cdna:GeneFinder chromosome:CEL140:III:10416034:10421240:1 11/11 None
M03C11.5.2 ENSEMBL cdna:known chromosome:CEL140:III:10415952:10421631:1 gene:M03C11.5 11/11 None
M03C11.5.1 ENSEMBL cdna:known chromosome:CEL140:III:10416022:10421631:1 gene:M03C11.5 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIII:10416029-10421236(+) 100.0 100.0
Public Domain and Genome References
Gene Title ATP-binding protein (AAA protein family member)
Ensembl M03C11.5
Entrez Gene 176460 Entrez gene
SwissProt P54813 EMBL-EBI
WormBase CE03496 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:18278_AT FtsH protease, putative at
ATH1-121501:266842_AT FtsH protease, putative at
CANINE:1587447_AT similar to YME1-like 1 isoform 3 cfa
CANINE_2:CFA.1083.1.S1_AT similar to YME1-like 1 isoform 3 cfa
CANINE_2:CFAAFFX.7542.1.S1_S_AT similar to YME1-like 1 isoform 3 cfa
DROSOPHILA_2:1638394_AT dm
DROSGENOME1:152570_AT dm
CHICKEN:GGA.8899.1.S1_S_AT YME1-like 1 (S. cerevisiae) gga
HG-U133A:201351_S_AT YME1-like 1 (S. cerevisiae) hs
HG-U133A_2:201351_S_AT YME1-like 1 (S. cerevisiae) hs
HG-U133_PLUS_2:201351_S_AT YME1-like 1 (S. cerevisiae) hs
HG-FOCUS:201351_S_AT YME1-like 1 (S. cerevisiae) hs
HG-U133A:201352_AT YME1-like 1 (S. cerevisiae) hs
HG-U133A_2:201352_AT YME1-like 1 (S. cerevisiae) hs
HG-U133_PLUS_2:201352_AT YME1-like 1 (S. cerevisiae) hs
HG-U133_PLUS_2:216304_X_AT YME1-like 1 (S. cerevisiae) hs
HG-U133A_2:216304_X_AT YME1-like 1 (S. cerevisiae) hs
HG-U133A:216304_X_AT YME1-like 1 (S. cerevisiae) hs
HG-U133_PLUS_2:232216_AT YME1-like 1 (S. cerevisiae) hs
HG-U133B:232216_AT YME1-like 1 (S. cerevisiae) hs
HU35KSUBA:RC_AA452161_AT YME1-like 1 (S. cerevisiae) hs
HU35KSUBA:W23553_AT YME1-like 1 (S. cerevisiae) hs
HU35KSUBA:HUM_ALU_AT YME1-like 1 (S. cerevisiae) hs
HU35KSUBB:HUM_ALU_AT YME1-like 1 (S. cerevisiae) hs
HU35KSUBC:HUM_ALU_AT YME1-like 1 (S. cerevisiae) hs
HU35KSUBD:HUM_ALU_AT YME1-like 1 (S. cerevisiae) hs
HUGENEFL:HUM_ALU_AT YME1-like 1 (S. cerevisiae) hs
HC-G110:HUM_ALU_AT YME1-like 1 (S. cerevisiae) hs
HU35KSUBA:AA306135_AT YME1-like 1 (S. cerevisiae) hs
HU35KSUBC:RC_AA425447_AT YME1-like 1 (S. cerevisiae) hs
U133_X3P:G7657688_3P_AT YME1-like 1 (S. cerevisiae) hs
U133_X3P:G4454687_3P_A_AT YME1-like 1 (S. cerevisiae) hs
U133_X3P:HS.287544.0.S1_3P_AT YME1-like 1 (S. cerevisiae) hs
HG-U95AV2:40988_AT YME1-like 1 (S. cerevisiae) hs
HG-U95C:51843_F_AT YME1-like 1 (S. cerevisiae) hs
HG-U95E:67175_AT YME1-like 1 (S. cerevisiae) hs
HG-U95D:70682_AT YME1-like 1 (S. cerevisiae) hs
MOE430A:1450954_AT YME1-like 1 (S. cerevisiae) mm
MOUSE430A_2:1450954_AT YME1-like 1 (S. cerevisiae) mm
MOUSE430_2:1450954_AT YME1-like 1 (S. cerevisiae) mm
MOE430A:1423361_AT YME1-like 1 (S. cerevisiae) mm
MOUSE430A_2:1423361_AT YME1-like 1 (S. cerevisiae) mm
MOUSE430_2:1423361_AT YME1-like 1 (S. cerevisiae) mm
MG-U74AV2:104535_AT YME1-like 1 (S. cerevisiae) mm
MOE430A:1423360_AT YME1-like 1 (S. cerevisiae) mm
MOUSE430A_2:1423360_AT YME1-like 1 (S. cerevisiae) mm
MOUSE430_2:1423360_AT YME1-like 1 (S. cerevisiae) mm
MOE430B:1437822_AT YME1-like 1 (S. cerevisiae) mm
MOUSE430_2:1437822_AT YME1-like 1 (S. cerevisiae) mm
MG-U74CV2:166123_AT YME1-like 1 (S. cerevisiae), mRNA (cDNA clone MGC:5753 IMAGE:3591123) mm
MG-U74CV2:168000_AT YME1-like 1 (S. cerevisiae), mRNA (cDNA clone MGC:5753 IMAGE:3591123) mm
MG-U74AV2:97102_AT YME1-like 1 (S. cerevisiae), mRNA (cDNA clone MGC:5753 IMAGE:3591123) mm
MU11KSUBA:AA276948_AT YME1-like 1 (S. cerevisiae), mRNA (cDNA clone MGC:5753 IMAGE:3591123) mm
MU19KSUBB:TC32393_AT YME1-like 1 (S. cerevisiae), mRNA (cDNA clone MGC:5753 IMAGE:3591123) mm
MU19KSUBC:TC35135_AT YME1-like 1 (S. cerevisiae), mRNA (cDNA clone MGC:5753 IMAGE:3591123) mm
MU19KSUBC:TC35135_G_AT YME1-like 1 (S. cerevisiae), mRNA (cDNA clone MGC:5753 IMAGE:3591123) mm
RG-U34C:RC_AA817882_AT YME1-like 1 (S. cerevisiae) rn
RAE230A:1368843_AT YME1-like 1 (S. cerevisiae) rn
RAT230_2:1368843_AT YME1-like 1 (S. cerevisiae) rn
RAE230B:1394059_S_AT YME1-like 1 (S. cerevisiae) rn
RAT230_2:1394059_S_AT YME1-like 1 (S. cerevisiae) rn
RAE230B:1385999_AT YME1-like 1 (S. cerevisiae) rn
RAT230_2:1385999_AT YME1-like 1 (S. cerevisiae) rn
RAE230A:1375841_AT YME1-like 1 (S. cerevisiae) rn
RAT230_2:1375841_AT YME1-like 1 (S. cerevisiae) rn
RG-U34B:RC_AA925799_AT YME1-like 1 (S. cerevisiae) rn
RG-U34C:RC_AI137819_AT YME1-like 1 (S. cerevisiae) rn
YEAST_2:1777772_AT Mitochondrial inner membrane protease of the AAA family, responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6508 proteolysis inferred from electronic annotation QuickGO AmiGO
30163 protein catabolism inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
166 nucleotide binding inferred from electronic annotation QuickGO AmiGO
4222 metalloendopeptidase activity inferred from electronic annotation QuickGO AmiGO
5524 ATP binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA88955 Hypothetical protein M03C11.5 [Caenorhabditis elegans] ref|NP_499298.1| M03C11.5 [Caenorhabditis elegans] sp|P54813|YME1_CAEEL YME1 protein homolog 0.0
blast CAE71473 Hypothetical protein CBG18391 [Caenorhabditis briggsae] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR000642 EMBL-EBI Peptidase M41 2.1E-122
Pfam IPR003959 EMBL-EBI AAA ATPase, central region 1.2E-87
Pfam IPR000642 EMBL-EBI Peptidase M41 2.1E-122
Pfam IPR003959 EMBL-EBI AAA ATPase, central region 1.2E-87
Pfam IPR000642 EMBL-EBI Peptidase M41 2.1E-122
Pfam IPR003959 EMBL-EBI AAA ATPase, central region 1.2E-87
Trans Membrane
ID Number Of Domains Domain Boundaries
SNAP00000000518 1 198-217
GENEFINDER00000000559 1 198-220
Sequence
Target Sequence 
>C. ELEGANS:193744_S_AT
ttccacgtggacaatctctcggacacactgcaatgcttcctgaaaaggatagttatcagt
tgactaaagcacaaatgcttgctacgttggatgtgatgatgggcggtcgggtggctgaag
agctcatctttggagatgataaggtcaccactggtgctgcggatgatttgagtaaggcca
ctcagttggcggtgcagatggttaaggtttttggaatgagtgataaggtcggactccgtg
atttcactgcccaagacaatgaaagtgcactggtaaaagtgtcggatttggcaccacaaa
cagccgaactaattgatgcagagattaatcgtgtactacaggagagctataaaagggcta
aagtcattttggaaaccaagaagaaagagcatcaactgctcgcggaagctcttctcgaat
acgaaactctctcagctgacgaggtgaaacgtgttatcagtggacagaaaatcaagcgac
caacaccggcggcagtgaagaaaagtaatgaaacaaaacgaaatcaaccgtcgcttgttc
ttc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCCACGTGGACAATCTCTCGGACA 652 699 1466 Antisense
TCGGACACACTGCAATGCTTCCTGA 302 607 1484 Antisense
GTCGGGTGGCTGAAGAGCTCATCTT 352 473 1571 Antisense
TCACCACTGGTGCTGCGGATGATTT 27 625 1610 Antisense
GTAAGGCCACTCAGTTGGCGGTGCA 196 461 1637 Antisense
TCCGTGATTTCACTGCCCAAGACAA 299 595 1700 Antisense
AAAAGTGTCGGATTTGGCACCACAA 338 133 1740 Antisense
GAGCATCAACTGCTCGCGGAAGCTC 324 389 1852 Antisense
GAATACGAAACTCTCTCAGCTGACG 9 327 1882 Antisense
CGACCAACACCGGCGGCAGTGAAGA 471 251 1942 Antisense
CGAAATCAACCGTCGCTTGTTCTTC 141 251 1984 Antisense
Sequence Source Affymetrix Proprietary Database