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[193733_at] inward rectifier potassium channel (IRK)

Description K04G11.5 /REP_DB=WormBase Gene ID /WP=CE11750 /GEN=irk-3 /TR=Q93849 /GB=CAB01762.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=inward rectifier potassium channel (IRK)
Cluster 6grp_high1_10_10 > 15      4grp_high_8_8 > 27      6grp_total > 14      4grp_total > 37      6grp_cgc > 23      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 223
1 2 3 4 range
A 305.2
(3)
P
177.4
(-1.5)
P
134.1
(-3)
P
298.9
(2.8)
P
171
B 177.5
(-0.3)
P
255.3
(3)
P
114.1
(-3)
A
136.5
(-2)
P
141
C 336.8
(3)
P
245
(-0)
P
156.2
(-3)
M
195.5
(-1.7)
P
181
avr 273.2
(3)
225.9
(0.9)
134.8
(-3)
210.3
(0.3)
138

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 217
1 2 3 4 5 6 range
A 227.5
(1.3)
P
272.7
(3)
P
150.9
(-1.5)
P
180
(-0.4)
P
143.1
(-1.8)
P
109
(-3)
A
164
B 216.2
(3)
P
209.1
(2.6)
P
155.4
(-0.7)
P
143.2
(-1.4)
P
152.4
(-0.9)
P
117.7
(-3)
P
99
C 323.8
(3)
P
246.3
(0.9)
P
176.4
(-1.1)
P
179.6
(-1)
P
106.6
(-3)
P
133.6
(-2.3)
P
217
avr 255.8
(3)
242.7
(2.4)
160.9
(-1.2)
167.6
(-0.9)
134
(-2.4)
120.1
(-3)
136
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 85
1 2 3 4 range
A 111.1
(3)
P
38.5
(-2.7)
P
35.1
(-3)
P
43.8
(-2.3)
P
76
B 56.6
(1.9)
P
63.1
(3)
P
26.4
(-3)
A
29.1
(-2.6)
P
37
C 111.5
(3)
P
70.4
(-0.1)
P
54.4
(-1.4)
M
33
(-3)
P
79
avr 93.1
(3)
57.3
(-0.7)
38.6
(-2.7)
35.3
(-3)
58

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 94
1 2 3 4 5 6 range
A 41.9
(-1.7)
P
97
(3)
P
32.9
(-2.5)
P
45.7
(-1.4)
P
43.2
(-1.6)
P
26.5
(-3)
A
71
B 75.2
(3)
P
69.6
(2.1)
P
37.7
(-3)
P
37.9
(-3)
P
61.9
(0.9)
P
43.9
(-2)
P
38
C 120
(3)
P
75.2
(-0.1)
P
44.9
(-2.3)
P
36.1
(-2.9)
P
34.5
(-3)
P
44.7
(-2.3)
P
86
avr 79
(2.8)
80.6
(3)
38.5
(-3)
39.9
(-2.8)
46.5
(-1.8)
38.4
(-3)
42
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193733_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.18051
Sequence Type Exemplar sequence
Representative Public ID K04G11.5 NCBI
Target Description K04G11.5 /REP_DB=WormBase Gene ID /WP=CE11750 /GEN=irk-3 /TR=Q93849 /GB=CAB01762.1 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=inward rectifier potassium channel (IRK)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077994(10)
Transcript Assignments
Representative
Transcript
Description Matching Probes Related Probesets by Grade
NM_077994 NCBI Caenorhabditis elegans Inward Rectifying K (potassium) channel family member (irk-3) (irk-3) mRNA, complete cds. 10/11 None
GENEFINDER00000024620 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:14353704:14359351:-1 10/11 None
K04G11.5 ENSEMBL cdna:known chromosome:CEL140:X:14353228:14358984:-1 gene:K04G11.5 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000024616 8/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:14353703-14358304(-) 100.0 100.0
Public Domain and Genome References
Gene Title inward rectifier potassium channel (IRK)
Gene Symbol irk-3
Ensembl K04G11.5
Entrez Gene 191696 Entrez gene
SwissProt Q93849 EMBL-EBI
WormBase CE35580 Wormbase
Functional Annotations
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6813 potassium ion transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
5242 inward rectifier potassium channel activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB01762 Hypothetical protein K04G11.5 [Caenorhabditis elegans] ref|NP_510395.3| Inward Rectifying K (potassium) channel family member (irk-3) [Caenorhabditis elegans] 0.0
blast CAE65616 Hypothetical protein CBG10649 [Caenorhabditis briggsae] 1.0E-128
blast CAC87637 inwardly rectifying K+ channel protein [Drosophila melanogaster] gb|AAF56107.1| CG6747-PA [Drosophila melanogaster] ref|NP_651131.2| CG6747-PA [Drosophila melanogaster] 1.0E-60
blast CAC87637 inwardly rectifying K+ channel protein [Drosophila melanogaster] gb|AAF56107.1| CG6747-PA [Drosophila melanogaster] ref|NP_651131.2| CG6747-PA [Drosophila melanogaster] 2.0E-60
Protein Domains
Database ID Description E-Value
Pfam IPR001838 EMBL-EBI K+ channel, inward rectifier 6.3E-92
Pfam IPR001838 EMBL-EBI K+ channel, inward rectifier 6.3E-92
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_510395.3 2 81-103,150-172
K04G11.5 2 81-103,150-172
GENEFINDER00000024620 2 148-170,217-239
Sequence
Target Sequence
>C. ELEGANS:193733_AT
gtattgccaacgttgacacgcttattagtgcttttttgttcagtatggaatcacaacata
ccatcggatacggactgcggtacatgacggatttatgtccacctgcatatctaacgcttt
gcgtacaatgcgtcgtaggagtctttttacaaactatcttagcgggaatcgttattgcga
aaattttaagaccaaaaaagcggcggcagagaggtgatcgagaattaattggtgttaagg
atatgaacgttggttatgatagtggatgggatcgtgtattactactctggcccattattg
tccgtcatgttataaatgaagacagtccactttatggaatgtcacgagaaaatattgtga
aagccgattttgaattaataatgacagtcgaaggaatagtcgaagcaacaggaatgacgt
ttcaagcaaggacgtcatttttacccgacgaaattttatggggttacaaattcaaaccga
tggtgttgatgaacgagaagctatccaagtatgaagtacactactcattttttgaccaga
ctga


BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position
Strandedness
GTATTGCCAACGTTGACACGCTTAT 621 451 218 Antisense
ACATACCATCGGATACGGACTGCGG 72 105 273 Antisense
TACGGACTGCGGTACATGACGGATT 44 647 286 Antisense
ATGACGGATTTATGTCCACCTGCAT 502 43 301 Antisense
CCACCTGCATATCTAACGCTTTGCG 94 275 316 Antisense
GCTTTGCGTACAATGCGTCGTAGGA 326 303 333 Antisense
GCGGCGGCAGAGAGGTGATCGAGAA 689 293 417 Antisense
GGATCGTGTATTACTACTCTGGCCC 300 511 486 Antisense
GCCCATTATTGTCCGTCATGTTATA 176 287 507 Antisense
CAAGCAAGGACGTCATTTTTACCCG 513 181 640 Antisense
ACTACTCATTTTTTGACCAGACTGA 198 101 737 Antisense
Sequence Source Affymetrix Proprietary Database