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[193729_at] WD domain, G-beta repeat (4 domains)

Description Y45F10B.10 /REP_DB=WormBase Gene ID /WP=CE18408 /GEN=qui-1 /TR=O62471 /GB=CAA16357.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=WD domain, G-beta repeat (4 domains)
Cluster 6grp_highest_10_10 > 60      6grp_high1_10_10 > 16      4grp_high_8_8 > 24      6grp_highest_nonorm > 70      6grp_total > 06      4grp_total > 39      6grp_highest_sub > De      6grp_cgc > 13      6grp_high1_sub > De      6grp_cgc_sub > De      6grp_total_sub > Decrease      6grp_rule_based > S1      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 466
1 2 3 4 range
A 546.5
(3)
P 		162.5
(-2.4)
P 		118.3
(-3)
A 		217.3
(-1.6)
P 		428
B 538.6
(3)
P 		135.3
(-2.3)
P 		80.2
(-3)
M 		259.7
(-0.7)
P 		458
C 425.3
(3)
P 		176.9
(-2.1)
M 		135.7
(-3)
P 		227.2
(-1.1)
P 		290
avr 503.5
(3) 		158.2
(-2.3) 		111.4
(-3) 		234.7
(-1.1) 		392

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 481
1 2 3 4 5 6 range
A 592.8
(3)
P 		385
(0.4)
P 		111.9
(-3)
P 		253.5
(-1.2)
P 		179.3
(-2.2)
P 		176.3
(-2.2)
P 		481
B 538.5
(3)
P 		431
(1.3)
P 		168.3
(-2.8)
P 		250.3
(-1.5)
P 		154
(-3)
P 		165.2
(-2.8)
P 		385
C 574.6
(3)
P 		327.9
(-0.3)
P 		289.3
(-0.9)
P 		139.1
(-2.9)
P 		207.6
(-2)
P 		130.7
(-3)
P 		444
avr 568.6
(3) 		381.3
(0.3) 		189.8
(-2.5) 		214.3
(-2.2) 		180.3
(-2.7) 		157.4
(-3) 		411
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 180
1 2 3 4 range
A 199
(3)
P 		35.3
(-2.8)
P 		30.9
(-3)
A 		31.8
(-3)
P 		168
B 171.8
(3)
P 		33.4
(-2.4)
P 		18.6
(-3)
M 		55.3
(-1.6)
P 		153
C 140.8
(3)
P 		50.9
(-2.3)
M 		47.3
(-2.5)
P 		38.3
(-3)
P 		103
avr 170.5
(3) 		39.9
(-2.7) 		32.3
(-3) 		41.8
(-2.6) 		138

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 189
1 2 3 4 5 6 range
A 109.3
(1.5)
P 		136.9
(3)
P 		24.4
(-3)
P 		64.3
(-0.9)
P 		54.1
(-1.4)
P 		42.9
(-2)
P 		113
B 187.4
(3)
P 		143.5
(1.2)
P 		40.9
(-3)
P 		66.3
(-2)
P 		62.6
(-2.1)
P 		61.6
(-2.2)
P 		147
C 213
(3)
P 		100.1
(-0.7)
P 		73.6
(-1.5)
P 		28
(-3)
P 		67.2
(-1.7)
P 		43.8
(-2.5)
P 		185
avr 169.9
(3) 		126.8
(0.9) 		46.3
(-3) 		52.9
(-2.7) 		61.3
(-2.3) 		49.4
(-2.8) 		124
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193729_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.10357
Sequence Type Exemplar sequence
Representative Public ID Y45F10B.10 NCBI
Target Description Y45F10B.10 /REP_DB=WormBase Gene ID /WP=CE18408 /GEN=qui-1 /TR=O62471 /GB=CAA16357.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=WD domain, G-beta repeat (4 domains)
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070212(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070212 NCBI Caenorhabditis elegans QUInine non-avoider family member (qui-1) (qui-1) mRNA, complete cds. 11/11 None
SNAP00000007852 ENSEMBL cdna:SNAP chromosome:CEL140:IV:13565167:13574310:1 11/11 None
GENEFINDER00000007873 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:13565957:13574310:1 11/11 None
Y45F10B.10 ENSEMBL cdna:known chromosome:CEL140:IV:13561842:13574388:1 gene:Y45F10B.10 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:13568559-13574316(+) 100.0 100.0
Public Domain and Genome References
Gene Title WD domain, G-beta repeat (4 domains)
Gene Symbol qui-1
Ensembl Y45F10B.10
Entrez Gene 178326 Entrez gene
SwissProt O62471 EMBL-EBI
WormBase CE36361 Wormbase
Functional Annotations
Ortholog
ID Title Organism
DROSOPHILA_2:1630676_AT dm
DROSOPHILA_2:1639615_S_AT dm
DROSGENOME1:151995_AT dm
DROSGENOME1:147442_AT dm
Protein Similarities
Method ID Description E-Value
blast CAA16357 Hypothetical protein Y45F10B.10 [Caenorhabditis elegans] ref|NP_502613.2| QUInine non-avoider family member (qui-1) [Caenorhabditis elegans] 0.0
blast CAE58586 Hypothetical protein CBG01752 [Caenorhabditis briggsae] 0.0
blast XP_781967 PREDICTED: similar to CG30116-PB, isoform B [Strongylocentrotus purpuratus] 1.0E-113
Protein Domains
Database ID Description E-Value
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 5.0E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.3E-5
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 2.0E-7
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0046
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0010
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.039
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.084
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 6.8E-9
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 4.7E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 5.0E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.3E-5
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 2.0E-7
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0046
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0010
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.039
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.084
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 6.8E-9
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 4.7E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 5.0E-10
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 1.3E-5
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 2.0E-7
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0046
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.0010
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.039
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 0.084
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 6.8E-9
Pfam IPR001680 EMBL-EBI G-protein beta WD-40 repeat 4.7E-10
Sequence
Target Sequence 
>C. ELEGANS:193729_AT
ttaacactacagcagccatcacgtcactgtcaatgactggggattctactgtcgtgtttt
caactacggaagatggctgggtagagacatggtctaccacgaaaggtcgcctactttcga
ccttcaacgctcatcgacctatcaagaagctcatcaactcgtacgaatctcaccgaatgc
tccttttgctcgaaaactgtgctcaactgccaattctctgtctacataatacccctgccg
taggagtagaggcaacaagacggcgaagtgcgagagctcaatctgtgtcaagtgcgtcga
atgagcccgtcgcatcgacaagtgctggtgagataaagaaggatcccatcttgtcatcga
ataacggaggaaatgcacaatctgctccgcg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTAACACTACAGCAGCCATCACGTC 387 683 2786 Antisense
GGGATTCTACTGTCGTGTTTTCAAC 267 497 2825 Antisense
GAAGCTCATCAACTCGTACGAATCT 167 343 2931 Antisense
AATGCTCCTTTTGCTCGAAAACTGT 675 165 2961 Antisense
AAACTGTGCTCAACTGCCAATTCTC 169 127 2979 Antisense
TTCTCTGTCTACATAATACCCCTGC 273 693 2999 Antisense
GACGGCGAAGTGCGAGAGCTCAATC 535 375 3044 Antisense
GAGCTCAATCTGTGTCAAGTGCGTC 555 387 3059 Antisense
CAAGTGCGTCGAATGAGCCCGTCGC 14 183 3074 Antisense
AAGAAGGATCCCATCTTGTCATCGA 109 153 3121 Antisense
GAGGAAATGCACAATCTGCTCCGCG 67 405 3152 Antisense
Sequence Source Affymetrix Proprietary Database