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[193723_s_at] human Max-interacting bHLH-Zip protein

Description R03E9.1 /REP_DB=WormBase Gene ID /WP=CE04784 /GEN=mdl-1 /TR=Q21663 /GB=AAC48067.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=human Max-interacting bHLH-Zip protein
Cluster 6grp_highest_10_10 > 90      6grp_high1_10_10 > 09      4grp_highest_8_8 > 47      4grp_high_8_8 > 11      6grp_highest_nonorm > 57      6grp_total > 02      4grp_total > 21      6grp_cgc > 52      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 3449
1 2 3 4 range
A 2398.6
(-0.2)
P 		1864.1
(-1.1)
P 		779.8
(-3)
P 		4228.4
(3)
P 		3449
B 2950.8
(1.3)
P 		1572.5
(-1.8)
P 		1006.5
(-3)
P 		3728.4
(3)
P 		2722
C 2376.5
(0.4)
P 		1536.5
(-1.4)
P 		798.1
(-3)
P 		3609.8
(3)
P 		2812
avr 2575.3
(0.4) 		1657.7
(-1.4) 		861.5
(-3) 		3855.5
(3) 		2994

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1820
1 2 3 4 5 6 range
A 3410.4
(2.8)
P 		3355.1
(2.6)
P 		1643
(-3)
P 		2094.4
(-1.5)
P 		3463.1
(3)
P 		2174.3
(-1.2)
P 		1820
B 2779
(0.7)
P 		3374.1
(3)
P 		1811.2
(-3)
P 		2742.7
(0.6)
P 		3109.3
(2)
P 		1916.5
(-2.6)
P 		1563
C 2180.8
(-0.9)
P 		3155.1
(2.9)
P 		1655.9
(-3)
P 		2563.6
(0.6)
P 		3180.3
(3)
P 		1802.6
(-2.4)
P 		1524
avr 2790.1
(1.1) 		3294.8
(3) 		1703.4
(-3) 		2466.9
(-0.1) 		3250.9
(2.8) 		1964.5
(-2) 		1591
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 737
1 2 3 4 range
A 873.3
(3)
P 		404.6
(-1.2)
P 		203.8
(-3)
P 		618.9
(0.7)
P 		670
B 941
(3)
P 		388.4
(-1.7)
P 		233.2
(-3)
P 		794.5
(1.8)
P 		708
C 786.7
(3)
P 		441.8
(-1.1)
P 		278.2
(-3)
P 		608.7
(0.9)
P 		509
avr 867
(3) 		411.6
(-1.3) 		238.4
(-3) 		674
(1.2) 		629

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 906
1 2 3 4 5 6 range
A 628.7
(-1.1)
P 		1193.2
(3)
P 		357.8
(-3)
P 		531.2
(-1.8)
P 		1045
(1.9)
P 		529.4
(-1.8)
P 		835
B 967
(0.8)
P 		1123.1
(2)
P 		439.8
(-3)
P 		726.4
(-0.9)
P 		1263.3
(3)
P 		714.7
(-1)
P 		824
C 808.3
(0.8)
P 		962.7
(2.3)
P 		421.4
(-3)
P 		515.5
(-2.1)
P 		1029.1
(3)
P 		603.4
(-1.2)
P 		608
avr 801.3
(0.4) 		1093
(2.8) 		406.3
(-3) 		591
(-1.4) 		1112.5
(3) 		615.8
(-1.2) 		706
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193723_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16279
Sequence Type Exemplar sequence
Representative Public ID R03E9.1 NCBI
Target Description R03E9.1 /REP_DB=WormBase Gene ID /WP=CE04784 /GEN=mdl-1 /TR=Q21663 /GB=AAC48067.1 /SUBMIT=ST.LOUIS /CHR=X /FEA=Sanger Annotation /DEF=human Max-interacting bHLH-Zip protein
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_076735(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_076735 NCBI Caenorhabditis elegans MAD-Like family member (mdl-1) (mdl-1) mRNA, complete cds. 11/11 None
SNAP00000044141 ENSEMBL cdna:SNAP chromosome:CEL140:X:6742439:6743622:1 11/11 None
GENEFINDER00000044149 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:6742439:6743622:1 11/11 None
R03E9.1 ENSEMBL cdna:known chromosome:CEL140:X:6742356:6743855:1 gene:R03E9.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:6742438-6743622(+) 100.0 100.0
Public Domain and Genome References
Gene Title human Max-interacting bHLH-Zip protein
Gene Symbol mdl-1
Ensembl R03E9.1
Entrez Gene 180942 Entrez gene
SwissProt Q21663 EMBL-EBI
WormBase CE04784 Wormbase
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast NP_509136 MAD-Like family member (mdl-1) [Caenorhabditis elegans] gb|AAC48067.1| Mad-like protein 1 [Caenorhabditis elegans] gb|AAB40927.1| MAD-like-1 homolog [Caenorhabditis elegans] 1.0E-123
blast NP_509136 MAD-Like family member (mdl-1) [Caenorhabditis elegans] gb|AAC48067.1| Mad-like protein 1 [Caenorhabditis elegans] gb|AAB40927.1| MAD-like-1 homolog [Caenorhabditis elegans] 1.0E-121
blast CAE65784 Hypothetical protein CBG10881 [Caenorhabditis briggsae] 1.0E-93
blast CAE65784 Hypothetical protein CBG10881 [Caenorhabditis briggsae] 3.0E-91
blast XP_852395 PREDICTED: similar to MAX interactor 1 isoform b [Canis familiaris] 7.0E-9
Protein Domains
Database ID Description E-Value
Pfam IPR001092 EMBL-EBI Basic helix-loop-helix dimerization domain bHLH 1.7E-15
Pfam IPR001092 EMBL-EBI Basic helix-loop-helix dimerization domain bHLH 1.7E-15
Sequence
Target Sequence 
>C. ELEGANS:193723_S_AT
ctccccaccagctagaaaatcttcgaagcacagccggacggcacacaacgagcttgagaa
aacccgccgagctaacctccgaggatgcctcgaaactctcaaaatgttggtcccatgtgt
cagcgatgccaccagaaatacgacgcttgcactgttaacacgagcccgagatcacatcat
tgaattgcaagacagcaatgcagctcaaatgaagaagcttaacgatttaagagacgaaca
ggatgaacttgttgcagaacttgcccaacttcaagccgacgaagaagttgctcaagcaac
tagccaagcttgccaaacgctttcacaaagcagacccgaatctcgagcatcttctttcac
ctccacatcttctcgcgattcaccctgctacctggagtactcaccatcaagcaaaccaat
ggattcacataagccaacaattatcgacctttacgctgaaggccttatcccaaggggtcc
aatcacttttccaagacctctggtctaccctcataatgtttttgatctcatgaatcttcc
acctac

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CTCCCCACCAGCTAGAAAATCTTCG 5 235 267 Antisense
CGAGCTAACCTCCGAGGATGCCTCG 247 249 334 Antisense
AATGTTGGTCCCATGTGTCAGCGAT 463 161 369 Antisense
TACGACGCTTGCACTGTTAACACGA 588 647 405 Antisense
TTAACACGAGCCCGAGATCACATCA 239 685 421 Antisense
GCCAAGCTTGCCAAACGCTTTCACA 169 279 569 Antisense
AAAGCAGACCCGAATCTCGAGCATC 607 123 593 Antisense
GCTACCTGGAGTACTCACCATCAAG 91 303 653 Antisense
TTACGCTGAAGGCCTTATCCCAAGG 122 681 717 Antisense
CCTCTGGTCTACCCTCATAATGTTT 610 267 763 Antisense
TTGATCTCATGAATCTTCCACCTAC 669 705 788 Antisense
Sequence Source Affymetrix Proprietary Database