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[193720_at] Drosophila tissue polarity protein like

Description T23D8.1 /REP_DB=WormBase Gene ID /WP=CE14048 /GEN=mom-5 /TR=O16147 /GB=CAB03398.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Drosophila tissue polarity protein like
Cluster 6grp_high1_10_10 > 34      4grp_high_8_8 > 04      6grp_total > 25      4grp_total > 05      6grp_cgc > 43      6grp_high1_sub > 02      6grp_cgc_sub > 02      6grp_total_sub > Decrease      6grp_rule_based > S2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 248
1 2 3 4 range
A 140.9
(-0.8)
P 		84.3
(-3)
M 		103.4
(-2.3)
P 		242.1
(3)
P 		158
B 192.5
(3)
P 		94.3
(-2.4)
P 		83.3
(-3)
A 		188.3
(2.8)
P 		109
C 133.7
(-2.3)
P 		128.6
(-2.5)
P 		108.5
(-3)
A 		331.2
(3)
P 		223
avr 155.7
(-0.8) 		102.4
(-2.8) 		98.4
(-3) 		253.9
(3) 		156

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 171
1 2 3 4 5 6 range
A 163.7
(3)
P 		114.1
(-0.4)
P 		77.3
(-3)
P 		100.6
(-1.4)
A 		95.5
(-1.7)
P 		111.6
(-0.6)
P 		86
B 141.8
(1)
P 		176.7
(3)
P 		76.6
(-2.7)
P 		126.2
(0.1)
P 		70.4
(-3)
P 		85.7
(-2.1)
P 		106
C 116
(-1.4)
P 		240.4
(3)
P 		122.2
(-1.2)
P 		69.7
(-3)
A 		77.7
(-2.7)
A 		82.8
(-2.5)
P 		171
avr 140.5
(0.7) 		177.1
(3) 		92
(-2.3) 		98.8
(-1.9) 		81.2
(-3) 		93.4
(-2.2) 		96
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 43
1 2 3 4 range
A 51.3
(3)
P 		18.3
(-3)
M 		27
(-1.4)
P 		35.4
(0.1)
P 		33
B 61.4
(3)
P 		23.3
(-2.4)
P 		19.3
(-3)
A 		40.1
(-0)
P 		42
C 44.3
(-0.7)
P 		37
(-3)
P 		37.8
(-2.7)
A 		55.8
(3)
P 		19
avr 52.3
(3) 		26.2
(-3) 		28
(-2.6) 		43.8
(1) 		26

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 59
1 2 3 4 5 6 range
A 30.2
(0.4)
P 		40.6
(3)
P 		16.8
(-3)
P 		25.5
(-0.8)
A 		28.8
(0)
P 		27.2
(-0.4)
P 		24
B 49.3
(1.6)
P 		58.8
(3)
P 		18.6
(-3)
P 		33.4
(-0.8)
P 		28.6
(-1.5)
P 		32
(-1)
P 		40
C 43
(-0.1)
P 		73.4
(3)
P 		31.1
(-1.3)
P 		14
(-3)
A 		25.1
(-1.9)
A 		27.7
(-1.6)
P 		59
avr 40.8
(0.2) 		57.6
(3) 		22.2
(-3) 		24.3
(-2.6) 		27.5
(-2.1) 		29
(-1.8) 		35
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193720_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.848
Sequence Type Exemplar sequence
Representative Public ID T23D8.1 NCBI
Target Description T23D8.1 /REP_DB=WormBase Gene ID /WP=CE14048 /GEN=mom-5 /TR=O16147 /GB=CAB03398.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=Drosophila tissue polarity protein like
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060234(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060234 NCBI Caenorhabditis elegans More Of MS family member (mom-5) (mom-5) mRNA, complete cds. 11/11 A 
SNAP00000036746 ENSEMBL cdna:SNAP chromosome:CEL140:I:9973762:9977455:1 11/11 None
GENEFINDER00000036758 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:9973762:9977455:1 11/11 None
T23D8.1 ENSEMBL cdna:known chromosome:CEL140:I:9973709:9978082:1 gene:T23D8.1 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:9973692-9977386(+) 100.0 100.0
Public Domain and Genome References
Gene Title Drosophila tissue polarity protein like
Gene Symbol mom-5
Ensembl T23D8.1
Entrez Gene 172856 Entrez gene
SwissProt O16147 EMBL-EBI
WormBase CE14048 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.3783.1.S1_AT similar to Frizzled 1 precursor (Frizzled-1) (Fz-1) (hFz1) (FzE1) cfa
DROSOPHILA_2:1631231_AT frizzled dm
DROSGENOME1:154598_AT frizzled dm
DROSOPHILA_2:1639883_AT frizzled dm
DROSGENOME1:143173_AT frizzled dm
CHICKEN:GGA.4087.1.S1_AT frizzled homolog 1 (Drosophila) gga
CHICKEN:GGA.4087.1.S2_AT frizzled homolog 1 (Drosophila) gga
HG-U133_PLUS_2:204451_AT frizzled homolog 1 (Drosophila) hs
HG-U133A:204451_AT frizzled homolog 1 (Drosophila) hs
HG-FOCUS:204451_AT frizzled homolog 1 (Drosophila) hs
HG-U133A_2:204451_AT frizzled homolog 1 (Drosophila) hs
HG-U133_PLUS_2:204452_S_AT frizzled homolog 1 (Drosophila) hs
HG-U133A_2:204452_S_AT frizzled homolog 1 (Drosophila) hs
HG-U133A:204452_S_AT frizzled homolog 1 (Drosophila) hs
HU35KSUBB:RC_AA158995_AT frizzled homolog 1 (Drosophila) hs
HU35KSUBC:RC_N70776_AT frizzled homolog 1 (Drosophila) hs
HU35KSUBD:RC_AA358618_S_AT frizzled homolog 1 (Drosophila) hs
U133_X3P:G5305406_3P_A_AT frizzled homolog 1 (Drosophila) hs
U133_X3P:G4503824_3P_AT frizzled homolog 1 (Drosophila) hs
HG-U95AV2:38300_AT frizzled homolog 1 (Drosophila) hs
MG-U74AV2:161040_AT frizzled homolog 1 (Drosophila) mm
MG-U74BV2:162796_AT frizzled homolog 1 (Drosophila) mm
MOE430A:1422985_AT frizzled homolog 1 (Drosophila) mm
MOUSE430A_2:1422985_AT frizzled homolog 1 (Drosophila) mm
MOUSE430_2:1422985_AT frizzled homolog 1 (Drosophila) mm
MOE430B:1437284_AT frizzled homolog 1 (Drosophila) mm
MOUSE430_2:1437284_AT frizzled homolog 1 (Drosophila) mm
MU11KSUBB:MSA.19508.0_S_AT Frizzled homolog 1 (Drosophila) (Fzd1), mRNA mm
MU11KSUBB:MSA.21920.0_S_AT Frizzled homolog 1 (Drosophila) (Fzd1), mRNA mm
MU19KSUBA:TC15071_AT Frizzled homolog 1 (Drosophila) (Fzd1), mRNA mm
MU19KSUBC:TC35550_AT Frizzled homolog 1 (Drosophila) (Fzd1), mRNA mm
RG-U34A:L02529_AT frizzled homolog 1 (Drosophila) rn
RAE230A:1370256_AT frizzled homolog 1 (Drosophila) rn
RAT230_2:1370256_AT frizzled homolog 1 (Drosophila) rn
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
7166 cell surface receptor linked signal transduction inferred from electronic annotation QuickGO AmiGO
7275 development inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16020 membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4888 transmembrane receptor activity inferred from electronic annotation QuickGO AmiGO
4926 non-G-protein coupled 7TM receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB03398 Hypothetical protein T23D8.1 [Caenorhabditis elegans] ref|NP_492635.1| More Of MS family member (mom-5) [Caenorhabditis elegans] gb|AAC47750.1| mom-5 gene product [Caenorhabditis elegans] 0.0
blast CAE60250 Hypothetical protein CBG03824 [Caenorhabditis briggsae] 0.0
blast XP_685530 PREDICTED: similar to 7-transmembrane receptor frizzled-1 [Danio rerio] 1.0E-105
Protein Domains
Database ID Description E-Value
Pfam IPR000539 EMBL-EBI Frizzled protein 1.0E-126
Pfam IPR000024 EMBL-EBI Frizzled CRD region 7.9E-77
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_492635.1 7 229-251,263-282,314-336,349-371,396-418,446-468,514-536
T23D8.1 7 229-251,263-282,314-336,349-371,396-418,446-468,514-536
SNAP00000036746 7 229-251,263-282,314-336,349-371,396-418,446-468,514-536
GENEFINDER00000036758 7 229-251,263-282,314-336,349-371,396-418,446-468,514-536
Sequence
Target Sequence 
>C. ELEGANS:193720_AT
ttccagcagttctctcggttactgtactagtgacaaattctgtcgatggagatgtattta
ctggaatctgttcagttggaaatttgaatccctctgctctcgtctatttctttttcactc
cgatcgttgtatcgttggcactcggagcagttttactcgtttgtggaatttggtcaatga
tccgtattcgaagttatattaaacttcaacacgccgatgttgagaggaatatcagtaaat
tggagaaattaatgttgagaatcggtgccttcgccataatgtactctctaccaactgcaa
tgaatgctgcaattatgtggtatcaggcagtaaatatgcctgcctggcttgaaggatggc
ttcatcatcgatgtgttcgacttcaagatcgagaattattcggtttcacgtatccagttg
atgattgtccgatggatccgaaagttgcagctccggagattattgtttttcttttaaaat
atgtgtctcaattggttgttggtataacctgtgccatttgggttgtctcttcaaaaactc
tttcaagttatcacaaggcttacctggcactctcttcgaggtcacctactgtacc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TTCCAGCAGTTCTCTCGGTTACTGT 55 697 1094 Antisense
TGGAAATTTGAATCCCTCTGCTCTC 691 547 1170 Antisense
TTCTTTTTCACTCCGATCGTTGTAT 258 691 1201 Antisense
ATCGTTGTATCGTTGGCACTCGGAG 578 35 1216 Antisense
GGCACTCGGAGCAGTTTTACTCGTT 498 533 1230 Antisense
AATGTTGAGAATCGGTGCCTTCGCC 52 165 1344 Antisense
TGTACTCTCTACCAACTGCAATGAA 496 559 1373 Antisense
TGCCTGCCTGGCTTGAAGGATGGCT 431 585 1430 Antisense
ACCTGTGCCATTTGGGTTGTCTCTT 297 87 1600 Antisense
TATCACAAGGCTTACCTGGCACTCT 246 659 1642 Antisense
TCTCTTCGAGGTCACCTACTGTACC 412 613 1664 Antisense
Sequence Source Affymetrix Proprietary Database