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[193708_s_at] peptidyl-prolyl cis-trans isomerase

Description T01B7.4 /REP_DB=WormBase Gene ID /WP=CE03588 /GEN=cyp-11 /TR=SW:P52018 /GB=CAA91297.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=peptidyl-prolyl cis-trans isomerase
Cluster 6grp_highest_10_10 > 89      6grp_high1_10_10 > 99      4grp_highest_8_8 > 19      4grp_high_8_8 > 63      6grp_highest_nonorm > 93      6grp_total > 99      4grp_total > 56      6grp_highest_sub > In      6grp_cgc > 79      6grp_cgc_sub > Da      6grp_total_sub > Increase      6grp_rule_based > S5      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 202
1 2 3 4 range
A 281
(-2.2)
P 		273.9
(-3)
P 		294.5
(-0.7)
P 		327.5
(3)
P 		54
B 316.7
(-2.7)
P 		307.8
(-3)
P 		467.5
(3)
P 		314.2
(-2.8)
P 		160
C 298.4
(-1.3)
P 		314.4
(-0.4)
P 		380.6
(3)
P 		265.2
(-3)
P 		115
avr 298.7
(-3) 		298.7
(-3) 		380.9
(3) 		302.3
(-2.7) 		82

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 419
1 2 3 4 5 6 range
A 335.3
(-1.2)
P 		273.3
(-3)
P 		362.1
(-0.4)
P 		313.4
(-1.8)
P 		478
(3)
P 		412.6
(1.1)
P 		205
B 378.4
(-2.2)
P 		372.2
(-2.4)
P 		335
(-3)
P 		380.7
(-2.2)
P 		678.6
(3)
P 		585.2
(1.4)
P 		344
C 320.5
(-1.7)
P 		312.8
(-1.9)
P 		259.3
(-3)
P 		289.3
(-2.4)
P 		452.6
(1)
P 		548.7
(3)
P 		289
avr 344.7
(-2.3) 		319.4
(-3) 		318.8
(-3) 		327.8
(-2.8) 		536.4
(3) 		515.5
(2.4) 		218
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 88
1 2 3 4 range
A 102.3
(3)
P 		59.5
(-1.7)
P 		77
(0.2)
P 		47.9
(-3)
P 		54
B 101
(1.9)
P 		76
(-1.7)
P 		108.3
(3)
P 		67
(-3)
P 		41
C 98.8
(0.7)
P 		90.4
(0.1)
P 		132.6
(3)
P 		44.7
(-3)
P 		88
avr 100.7
(2.4) 		75.3
(-0.5) 		106
(3) 		53.2
(-3) 		53

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 218
1 2 3 4 5 6 range
A 61.8
(-3)
P 		97.2
(-0.4)
P 		78.9
(-1.8)
P 		79.5
(-1.7)
P 		144.2
(3)
P 		100.5
(-0.2)
P 		82
B 131.7
(-1.4)
P 		123.9
(-1.7)
P 		81.3
(-3)
P 		100.8
(-2.4)
P 		275.7
(3)
P 		218.2
(1.2)
P 		194
C 118.8
(-0.1)
P 		95.4
(-1.2)
P 		66
(-2.6)
P 		58.2
(-3)
P 		146.4
(1.2)
P 		183.7
(3)
P 		126
avr 104.1
(-1.5) 		105.5
(-1.4) 		75.4
(-3) 		79.5
(-2.8) 		188.8
(3) 		167.5
(1.9) 		113
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193708_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.3492
Sequence Type Exemplar sequence
Representative Public ID T01B7.4 NCBI
Target Description T01B7.4 /REP_DB=WormBase Gene ID /WP=CE03588 /GEN=cyp-11 /TR=SW:P52018 /GB=CAA91297.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=peptidyl-prolyl cis-trans isomerase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063454(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063454 NCBI Caenorhabditis elegans CYclophyliN family member (cyn-11) (cyn-11) mRNA, complete cds. 11/11 None
SNAP00000025604 ENSEMBL cdna:SNAP chromosome:CEL140:II:8715116:8716203:-1 9/11 None
GENEFINDER00000025628 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:8715116:8716203:-1 11/11 None
T01B7.4 ENSEMBL cdna:known chromosome:CEL140:II:8715116:8716204:-1 gene:T01B7.4 11/11 None
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:8715112-8716200(-) 100.0 100.0
Public Domain and Genome References
Gene Title peptidyl-prolyl cis-trans isomerase
Gene Symbol cyn-11
Ensembl T01B7.4
Entrez Gene 174394 Entrez gene
SwissProt P52018 EMBL-EBI
WormBase CE03588 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:12432_AT peptidyl-prolyl cis-trans isomerase, putative / cyclophilin, putative / rotamase, putative at
ATH1-121501:266411_AT peptidyl-prolyl cis-trans isomerase, putative / cyclophilin, putative / rotamase, putative at
CANINE_2:CFAAFFX.4685.1.S1_S_AT similar to peptidyl prolyl isomerase H cfa
DROSOPHILA_2:1627399_AT dm
DROSGENOME1:146684_AT dm
CHICKEN:GGA.7074.1.S1_AT similar to peptidyl prolyl isomerase H; cyclophilin H; rotamase H gga
HG-U133_PLUS_2:204228_AT peptidyl prolyl isomerase H (cyclophilin H) hs
HG-U133A:204228_AT peptidyl prolyl isomerase H (cyclophilin H) hs
HG-FOCUS:204228_AT peptidyl prolyl isomerase H (cyclophilin H) hs
HG-U133A_2:204228_AT peptidyl prolyl isomerase H (cyclophilin H) hs
HU35KSUBA:RC_AA403116_AT peptidyl prolyl isomerase H (cyclophilin H) hs
U133_X3P:G5454153_3P_AT peptidyl prolyl isomerase H (cyclophilin H) hs
HG-U95AV2:38352_AT peptidyl prolyl isomerase H (cyclophilin H) hs
HG-U95C:63947_AT peptidyl prolyl isomerase H (cyclophilin H) hs
HG-U95D:82401_AT peptidyl prolyl isomerase H (cyclophilin H) hs
HG-U95D:91767_S_AT Peptidyl prolyl isomerase H (cyclophilin H) hs
MOE430A:1429832_AT peptidyl prolyl isomerase H mm
MOUSE430A_2:1429832_AT peptidyl prolyl isomerase H mm
MOUSE430_2:1429832_AT peptidyl prolyl isomerase H mm
MG-U74AV2:160456_AT peptidyl prolyl isomerase H mm
MU11KSUBB:MSA.5891.0_S_AT peptidyl prolyl isomerase H mm
MG-U74CV2:167111_R_AT peptidyl prolyl isomerase H mm
MOE430A:1424136_A_AT peptidyl prolyl isomerase H mm
MOUSE430A_2:1424136_A_AT peptidyl prolyl isomerase H mm
MOUSE430_2:1424136_A_AT peptidyl prolyl isomerase H mm
MOE430A:1431506_S_AT peptidyl prolyl isomerase H mm
MOUSE430A_2:1431506_S_AT peptidyl prolyl isomerase H mm
MOUSE430_2:1431506_S_AT peptidyl prolyl isomerase H mm
MOE430A:1431505_AT peptidyl prolyl isomerase H mm
MOUSE430A_2:1431505_AT peptidyl prolyl isomerase H mm
MOUSE430_2:1431505_AT peptidyl prolyl isomerase H mm
MG-U74BV2:116750_AT peptidyl prolyl isomerase H mm
MU19KSUBA:TC14380_AT Peptidyl prolyl isomerase H (Ppih), mRNA mm
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6457 protein folding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA91297 Hypothetical protein T01B7.4 [Caenorhabditis elegans] ref|NP_495855.1| CYclophyliN family member (cyn-11) [Caenorhabditis elegans] sp|P52018|CYP11_CAEEL Peptidyl-prolyl cis-trans isomerase 11 (PPIase) (Rotamase) (Cyclophilin-11) gb|AAC47115.1| cyclophilin isoform 11 (CYP-11) 1.0E-106
blast CAE59725 Hypothetical protein CBG03161 [Caenorhabditis briggsae] 1.0E-105
blast CAA91297 Hypothetical protein T01B7.4 [Caenorhabditis elegans] ref|NP_495855.1| CYclophyliN family member (cyn-11) [Caenorhabditis elegans] sp|P52018|CYP11_CAEEL Peptidyl-prolyl cis-trans isomerase 11 (PPIase) (Rotamase) (Cyclophilin-11) gb|AAC47115.1| cyclophilin isoform 11 (CYP-11) 2.0E-88
blast CAE59725 Hypothetical protein CBG03161 [Caenorhabditis briggsae] 9.0E-88
blast EAA04625 ENSANGP00000018327 [Anopheles gambiae str. PEST] ref|XP_308440.2| ENSANGP00000018327 [Anopheles gambiae str. PEST] 5.0E-75
Protein Domains
Database ID Description E-Value
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 1.0E-92
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 1.6E-57
Pfam IPR002130 EMBL-EBI Peptidyl-prolyl cis-trans isomerase, cyclophilin type 3.2E-10
Sequence
Target Sequence 
>C. ELEGANS:193708_S_AT
tacgacaagtttgccgagcagctccgtcatccggataacccaatcgtttttctagaagtt
accgccggtggtgcaccaatcggaactattgttatcgagttatttgctgatgtaacaccg
agaactgctgaaaactttcgtcagttctgtacaggagaatacaaaaaagatggtgtccca
aacggatacaaaaactgcacatttcatcgtgtgatcaaggactttatgattcagggtggc
gacttctgcaacggcgatggaaccggtttgatgagcatctatggttcaaagttccgtgac
gagaatttcgagctgaagcacataggaccaggaatgctttcgatggctaacgctggctct
gacacaaatggttgtcagttttttatcacttgcgcaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
TACGACAAGTTTGCCGAGCAGCTCC 429 647 22 Antisense
GTCATCCGGATAACCCAATCGTTTT 369 467 47 Antisense
TTTCTAGAAGTTACCGCCGGTGGTG 367 439 70 Antisense
GCCGGTGGTGCACCAATCGGAACTA 451 281 85 Antisense
GAAAACTTTCGTCAGTTCTGTACAG 381 353 151 Antisense
TGATTCAGGGTGGCGACTTCTGCAA 195 565 248 Antisense
GGCGATGGAACCGGTTTGATGAGCA 270 541 274 Antisense
GAGCATCTATGGTTCAAAGTTCCGT 525 387 294 Antisense
ATGCTTTCGATGGCTAACGCTGGCT 362 43 355 Antisense
TAACGCTGGCTCTGACACAAATGGT 195 635 369 Antisense
GTCAGTTTTTTATCACTTGCGCAAA 347 467 395 Antisense
Sequence Source Affymetrix Proprietary Database