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[193703_s_at]

Description F33D4.2B /REP_DB=WormBase Gene ID /WP=CE24938 /CHR=4 /FEA=Sanger Annotation /DEF=locus:itr-1 inositol 1,4,5-triphosphate receptor (ST.LOUIS) TR:O61194 protein_id:AAB88375.1
Cluster 6grp_high1_10_10 > 54      6grp_total > 55      4grp_total > 47      6grp_cgc > 46      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 178
1 2 3 4 range
A 358.7
(3)
P 		219.5
(-3)
P 		244.3
(-1.9)
P 		312.3
(1)
A 		139
B 339.1
(3)
P 		212.8
(-1.8)
P 		196.3
(-2.4)
P 		180.7
(-3)
A 		158
C 291.9
(3)
P 		215.1
(-1.5)
P 		272.5
(1.9)
P 		190.1
(-3)
A 		102
avr 329.9
(3) 		215.8
(-3) 		237.7
(-1.8) 		227.7
(-2.4) 		114

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 223
1 2 3 4 5 6 range
A 186.9
(-0.5)
A 		239.2
(3)
P 		223.1
(1.9)
P 		207.7
(0.9)
P 		150.8
(-3)
P 		208.9
(0.9)
P 		88
B 166.1
(0.2)
P 		185
(1)
P 		197.5
(1.5)
P 		198
(1.5)
P 		86.9
(-3)
P 		233.7
(3)
P 		147
C 190.9
(-0.8)
P 		225.7
(0.3)
P 		309.6
(3)
P 		140.2
(-2.4)
A 		120.4
(-3)
P 		240.8
(0.8)
P 		189
avr 181.3
(-0) 		216.6
(1.7) 		243.4
(3) 		182
(0) 		119.4
(-3) 		227.8
(2.2) 		124
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 99
1 2 3 4 range
A 130.6
(3)
P 		47.6
(-2.9)
P 		63.9
(-1.7)
P 		45.7
(-3)
A 		85
B 108.1
(3)
P 		52.6
(-1.8)
P 		45.5
(-2.4)
P 		38.5
(-3)
A 		70
C 96.6
(3)
P 		61.8
(-0.2)
P 		95
(2.9)
P 		32.1
(-3)
A 		65
avr 111.8
(3) 		54
(-1.8) 		68.1
(-0.6) 		38.8
(-3) 		73

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 59
1 2 3 4 5 6 range
A 34.4
(-3)
A 		85.1
(3)
P 		48.6
(-1.3)
P 		52.7
(-0.8)
P 		45.5
(-1.7)
P 		50.9
(-1)
P 		51
B 57.8
(-0.4)
P 		61.6
(0)
P 		48
(-1.5)
P 		52.4
(-1)
P 		35.3
(-3)
P 		87.1
(3)
P 		52
C 70.8
(1.9)
P 		68.9
(1.7)
P 		78.8
(2.8)
P 		28.2
(-3)
A 		39
(-1.8)
P 		80.6
(3)
P 		52
avr 54.3
(-0.4) 		71.9
(2.8) 		58.5
(0.4) 		44.4
(-2.2) 		39.9
(-3) 		72.9
(3) 		33
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193703_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.8953
Sequence Type Exemplar sequence
Representative Public ID F33D4.2B NCBI
Target Description F33D4.2B /REP_DB=WormBase Gene ID /WP=CE24938 /CHR=4 /FEA=Sanger Annotation /DEF=locus:itr-1 inositol 1,4,5-triphosphate receptor (ST.LOUIS) TR:O61194 protein_id:AAB88375.1
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_001027999(11), NM_001028000(11), NM_001028002(11), NM_001028001(11), NM_001028003(9)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_001027999 NCBI Caenorhabditis elegans Inositol Triphosphate Receptor family member (itr-1) (itr-1) mRNA, complete cds. 11/11 None
NM_001028000 NCBI Caenorhabditis elegans Inositol Triphosphate Receptor family member (itr-1) (itr-1) mRNA, complete cds. 11/11 None
NM_001028002 NCBI Caenorhabditis elegans Inositol Triphosphate Receptor family member (itr-1) (itr-1) mRNA, complete cds. 11/11 None
NM_001028001 NCBI Caenorhabditis elegans Inositol Triphosphate Receptor family member (itr-1) (itr-1) mRNA, complete cds. 11/11 None
NM_001028003 NCBI Caenorhabditis elegans Inositol Triphosphate Receptor family member (itr-1) (itr-1) mRNA, complete cds. 9/11 None
SNAP00000032720 ENSEMBL cdna:SNAP chromosome:CEL140:IV:7685641:7696687:1 11/11 None
GENEFINDER00000032732 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:7681694:7692973:1 11/11 None
F33D4.2a ENSEMBL cdna:known chromosome:CEL140:IV:7675157:7696907:1 gene:F33D4.2 11/11 A 
F33D4.2d ENSEMBL cdna:known chromosome:CEL140:IV:7677552:7696687:1 gene:F33D4.2 11/11 A 
F33D4.2f ENSEMBL cdna:known chromosome:CEL140:IV:7681343:7696907:1 gene:F33D4.2 11/11 A 
F33D4.2e ENSEMBL cdna:known chromosome:CEL140:IV:7681343:7696907:1 gene:F33D4.2 11/11 A 
F33D4.2g ENSEMBL cdna:known chromosome:CEL140:IV:7681409:7691799:1 gene:F33D4.2 9/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:7681699-7692258(+) 100.0 100.0
Public Domain and Genome References
Ensembl F33D4.2
Functional Annotations
Protein Similarities
Method ID Description E-Value
blast AAW30668 Inositol triphosphate receptor protein 1, isoform a [Caenorhabditis elegans] emb|CAB45861.1| inositol 1,4,5-trisphosphate receptor [Caenorhabditis elegans] ref|NP_001023170.1| Inositol Triphosphate Receptor family member (itr-1) [Caenorhabditis elegans] 0.0
blast AAW30669 Inositol triphosphate receptor protein 1, isoform d [Caenorhabditis elegans] emb|CAB45862.1| inositol 1,4,5-trisphosphate receptor [Caenorhabditis elegans] ref|NP_001023171.1| Inositol Triphosphate Receptor family member (itr-1) [Caenorhabditis elegans] 0.0
blast AAK68366 Inositol triphosphate receptor protein 1, isoform f [Caenorhabditis elegans] emb|CAB45860.1| inositol 1,4,5-trisphosphate receptor [Caenorhabditis elegans] ref|NP_001023173.1| Inositol Triphosphate Receptor family member (itr-1) [Caenorhabditis elegans] gb|AAF05302.1| inositol 1,4,5-trisphosphate receptor [Caenorhabditis elegans] 0.0
blast AAK68365 Inositol triphosphate receptor protein 1, isoform e [Caenorhabditis elegans] emb|CAB45863.1| inositol 1,4,5-trisphosphate receptor [Caenorhabditis elegans] ref|NP_001023172.1| Inositol Triphosphate Receptor family member (itr-1) [Caenorhabditis elegans] 0.0
Protein Domains
Database ID Description E-Value
Pfam IPR005821 EMBL-EBI Ion transport protein 2.6E-12
Pfam IPR003608 EMBL-EBI MIR domain 6.7E-6
Pfam IPR003608 EMBL-EBI MIR domain 5.4E-15
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 9.5E-53
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 3.0E-22
Pfam IPR005821 EMBL-EBI Ion transport protein 2.6E-12
Pfam IPR003608 EMBL-EBI MIR domain 6.7E-6
Pfam IPR003608 EMBL-EBI MIR domain 5.4E-15
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 9.5E-53
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 3.0E-22
Pfam IPR005821 EMBL-EBI Ion transport protein 2.6E-12
Pfam IPR003608 EMBL-EBI MIR domain 6.7E-6
Pfam IPR003608 EMBL-EBI MIR domain 5.4E-15
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 9.5E-53
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 3.0E-22
Pfam IPR005821 EMBL-EBI Ion transport protein 2.6E-12
Pfam IPR003608 EMBL-EBI MIR domain 3.5E-12
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 9.5E-53
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 3.0E-22
Pfam IPR005821 EMBL-EBI Ion transport protein 2.6E-12
Pfam IPR003608 EMBL-EBI MIR domain 5.4E-15
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 9.5E-53
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 3.0E-22
Pfam IPR003608 EMBL-EBI MIR domain 7.6E-12
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 9.5E-53
Pfam IPR000699 EMBL-EBI Intracellular calcium-release channel 3.0E-22
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_001023170.1 5 2475-2497,2510-2532,2571-2593,2616-2638,2731-2753
NP_001023171.1 5 2419-2441,2454-2476,2515-2537,2560-2582,2675-2697
NP_001023173.1 5 2429-2451,2464-2486,2525-2547,2570-2592,2685-2707
NP_001023172.1 5 2440-2462,2475-2497,2536-2558,2581-2603,2696-2718
F33D4.2a 5 2475-2497,2510-2532,2571-2593,2616-2638,2731-2753
F33D4.2d 5 2419-2441,2454-2476,2515-2537,2560-2582,2675-2697
F33D4.2f 5 2429-2451,2464-2486,2525-2547,2570-2592,2685-2707
F33D4.2e 5 2440-2462,2475-2497,2536-2558,2581-2603,2696-2718
SNAP00000032720 5 2143-2165,2178-2200,2239-2261,2284-2306,2399-2421
Sequence
Target Sequence 
>C. ELEGANS:193703_S_AT
aagagcacaatatcacgctcccagcaacacttgctggaccacagatgtctggtcaaacgt
cggttcgacaaaaatggcaacaagctgcgtcttctgcaaaatggattggaattggaaaga
gactcaatcgtcaaaatacgctcaatcctggtcatcgactctatggaacatcaaactcta
tgactgagcatacctctgcaaatgttgtaacctgttatcatatgatgatcggagagttta
aattctatcttcatccacttcatgctgccgaaggaagtgttcttgttgaagttctacata
cacctgaactactcttcccagaaggatcagcacttcgtgatcaatgtgctcgtggaggtg
ttgttgcaaaactcattcaacattgtaaaaccctgatgcaaaacaaacaagataatctct
gtgctcgtgtgcttcagacgttgtgcaaaatgtgcgattgcacaaaacagcagcttactc
atcagggccaacagcttcggcaacttctgctccaaagatactttggacatcataataatc
atcacccaccattagatcggcaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAGAGCACAATATCACGCTCCCAGC 147 153 4844 Antisense
GCAACACTTGCTGGACCACAGATGT 507 319 4867 Antisense
AGATGTCTGGTCAAACGTCGGTTCG 582 67 4886 Antisense
TGGCAACAAGCTGCGTCTTCTGCAA 234 547 4918 Antisense
AAATACGCTCAATCCTGGTCATCGA 231 117 4977 Antisense
TGGTCATCGACTCTATGGAACATCA 132 553 4992 Antisense
ACTCTATGACTGAGCATACCTCTGC 395 99 5018 Antisense
ATACCTCTGCAAATGTTGTAACCTG 146 23 5033 Antisense
TTCTACATACACCTGAACTACTCTT 164 689 5135 Antisense
GGACATCATAATAATCATCACCCAC 362 525 5368 Antisense
TCATCACCCACCATTAGATCGGCAA 355 619 5382 Antisense
Sequence Source Affymetrix Proprietary Database