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[193702_s_at] PDZ domain (Also known as DHR or GLGF).

Description T26E3.3 /REP_DB=WormBase Gene ID /WP=CE28089 /GEN=par-6 /TR=Q9NAN2 /GB=CAB61018.2 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=PDZ domain (Also known as DHR or GLGF).
Cluster 6grp_highest_10_10 > 71      6grp_high1_10_10 > 28      4grp_highest_8_8 > 08      4grp_high_8_8 > 44      6grp_highest_nonorm > 80      6grp_total > 18      4grp_total > 51      6grp_highest_sub > De      6grp_cgc > 06      6grp_high1_sub > De      6grp_cgc_sub > Cu      6grp_total_sub > Decrease      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 144
1 2 3 4 range
A 251.4
(-0.8)
P 		292.7
(3)
P 		247.7
(-1.1)
P 		227.2
(-3)
P 		66
B 233.8
(-1.1)
P 		281.9
(2.7)
P 		285.7
(3)
P 		209.2
(-3)
P 		77
C 271.4
(0.6)
P 		329.5
(3)
P 		287.4
(1.2)
P 		186
(-3)
P 		144
avr 252.2
(-0.1) 		301.4
(3) 		273.6
(1.2) 		207.5
(-3) 		94

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 251
1 2 3 4 5 6 range
A 222.7
(2.4)
P 		228.9
(3)
P 		175.7
(-1.9)
P 		173.9
(-2)
P 		163.3
(-3)
P 		184.5
(-1.1)
P 		66
B 233.8
(3)
P 		181.6
(-1.4)
P 		217.9
(1.6)
P 		178.4
(-1.7)
P 		163.2
(-3)
P 		197.3
(-0.1)
P 		71
C 356.1
(3)
P 		176.8
(-1.3)
P 		199.6
(-0.7)
P 		104.9
(-3)
P 		246.4
(0.4)
P 		205.3
(-0.6)
P 		251
avr 270.9
(3) 		195.8
(-0.8) 		197.7
(-0.7) 		152.4
(-3) 		191
(-1) 		195.7
(-0.8) 		119
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 69
1 2 3 4 range
A 91.5
(3)
P 		63.5
(0.1)
P 		64.7
(0.2)
P 		33.3
(-3)
P 		58
B 74.6
(3)
P 		69.6
(2)
P 		66.2
(1.3)
P 		44.6
(-3)
P 		30
C 89.8
(2.1)
P 		94.7
(2.5)
P 		100.2
(3)
P 		31.4
(-3)
P 		69
avr 85.3
(3) 		75.9
(1.8) 		77
(2) 		36.4
(-3) 		49

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 111
1 2 3 4 5 6 range
A 41
(-2.6)
P 		81.4
(3)
P 		38.3
(-3)
P 		44.1
(-2.2)
P 		49.3
(-1.5)
P 		44.9
(-2.1)
P 		43
B 81.3
(3)
P 		60.5
(-0.7)
P 		52.9
(-2)
P 		47.3
(-3)
P 		66.3
(0.4)
P 		73.6
(1.6)
P 		34
C 132
(3)
P 		54
(-1.2)
P 		50.8
(-1.4)
P 		21.1
(-3)
P 		79.7
(0.2)
P 		68.7
(-0.4)
P 		111
avr 84.8
(3) 		65.3
(0.5) 		47.3
(-1.8) 		37.5
(-3) 		65.1
(0.5) 		62.4
(0.2) 		47
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193702_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.2149
Sequence Type Exemplar sequence
Representative Public ID T26E3.3 NCBI
Target Description T26E3.3 /REP_DB=WormBase Gene ID /WP=CE28089 /GEN=par-6 /TR=Q9NAN2 /GB=CAB61018.2 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=PDZ domain (Also known as DHR or GLGF).
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_060807(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_060807 NCBI Caenorhabditis elegans abnormal embryonic PARtitioning of cytoplasm family member (par-6) (par-6) mRNA, complete cds. 11/11 A 
SNAP00000034748 ENSEMBL cdna:SNAP chromosome:CEL140:I:12673241:12682166:1 11/11 None
GENEFINDER00000034755 ENSEMBL cdna:GeneFinder chromosome:CEL140:I:12677747:12682166:1 11/11 None
T26E3.3 ENSEMBL cdna:known chromosome:CEL140:I:12677501:12682570:1 gene:T26E3.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:12677677-12682097(+) 100.0 100.0
Public Domain and Genome References
Gene Title PDZ domain (Also known as DHR or GLGF).
Gene Symbol par-6
Ensembl T26E3.3
Entrez Gene 173137 Entrez gene
SwissProt Q9NAN2 EMBL-EBI
WormBase CE28089 Wormbase
Functional Annotations
Ortholog
ID Title Organism
CANINE_2:CFAAFFX.985.1.S1_AT similar to par-6 partitioning defective 6 homolog gamma cfa
DROSOPHILA_2:1625748_S_AT dm
DROSGENOME1:154471_AT dm
CHICKEN:GGAAFFX.8663.1.S1_AT similar to Par-6 partitioning defective 6 homolog gamma gga
HG-U133_PLUS_2:232132_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HG-U133B:232132_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HG-U133_PLUS_2:224538_S_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HG-U133B:224538_S_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HU35KSUBA:RC_AA456039_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
U133_X3P:G13537118_3P_S_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
U133_X3P:HS.105421.0.A1_3P_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HG-U133_PLUS_2:227204_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HG-U133B:227204_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HG-U95B:48050_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HG-U95E:84124_AT par-6 partitioning defective 6 homolog gamma (C. elegans) hs
U133_X3P:HS2.182262.1.S1_3P_AT Par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HG-U133_PLUS_2:1558845_AT Par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HG-U95E:71173_AT Par-6 partitioning defective 6 homolog gamma (C. elegans) hs
HG-U95E:85077_R_AT Par-6 partitioning defective 6 homolog gamma (C. elegans) hs
MG-U74BV2:106623_AT par-6 partitioning defective 6 homolog gamma (C. elegans) mm
MOE430A:1450025_AT par-6 partitioning defective 6 homolog gamma (C. elegans) mm
MOUSE430A_2:1450025_AT par-6 partitioning defective 6 homolog gamma (C. elegans) mm
MOUSE430_2:1450025_AT par-6 partitioning defective 6 homolog gamma (C. elegans) mm
MOE430A:1420851_AT par-6 partitioning defective 6 homolog gamma (C. elegans) mm
MOUSE430A_2:1420851_AT par-6 partitioning defective 6 homolog gamma (C. elegans) mm
MOUSE430_2:1420851_AT par-6 partitioning defective 6 homolog gamma (C. elegans) mm
MG-U74CV2:140654_AT Par-6 partitioning defective 6 homolog gamma (C. elegans), mRNA (cDNA clone MGC:47087 IMAGE:3483559) mm
MU19KSUBB:TC29445_AT Par-6 partitioning defective 6 homolog gamma (C. elegans), mRNA (cDNA clone MGC:47087 IMAGE:3483559) mm
RAE230B:1385974_AT par-6 partitioning defective 6 homolog gamma (C. elegans) (predicted) rn
RAT230_2:1385974_AT par-6 partitioning defective 6 homolog gamma (C. elegans) (predicted) rn
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
5515 protein binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB61018 Hypothetical protein T26E3.3 [Caenorhabditis elegans] ref|NP_493208.1| abnormal embryonic PARtitioning of cytoplasm family member (par-6) [Caenorhabditis elegans] sp|Q9NAN2|PAR6_CAEEL Partitioning defective 6 protein gb|AAD15926.1| PAR-6 [Caenorhabditis elegans] 1.0E-172
blast T25297 hypothetical protein T26E3.3 - Caenorhabditis elegans 1.0E-166
blast CAE64104 Hypothetical protein CBG08713 [Caenorhabditis briggsae] 1.0E-151
Protein Domains
Database ID Description E-Value
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 1.4E-7
Pfam IPR000270 EMBL-EBI Octicosapeptide/Phox/Bem1p 1.2E-16
Pfam IPR006575 EMBL-EBI RWD 1.9E-33
Pfam IPR001478 EMBL-EBI PDZ/DHR/GLGF domain 1.4E-7
Pfam IPR000270 EMBL-EBI Octicosapeptide/Phox/Bem1p 1.2E-16
Sequence
Target Sequence 
>C. ELEGANS:193702_S_AT
cgacaggtctctgcaatcatcgacgtggacattgtgccagaagctcatcgccgtgtccgt
ctctgcaagcacggacaagaacgaccacttggattctatattcgtgacggaacatcggtt
cgagtgacagaacgaggcgtcgtcaaagtttcaggaattttcatttcccggcttgtcgat
ggtgggctcgccgagtccacaggccttcttggtgttaatgacgaggttctcggaaagacg
ctggatcaggtcactgatatgatggtcgccaatgctcataacttgattattactgtaaaa
cctgccaaccaacgaaacacactgtcacgaggaccgtcacaacaaggaacaccgaacgcc
agtgagatgtcggccgccaccgcagccgctacaggtggaattcagcgcccgatgaaaatg
aacggaagctccgacggcagttatcatcc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CGACAGGTCTCTGCAATCATCGACG 486 251 427 Antisense
GACATTGTGCCAGAAGCTCATCGCC 587 369 454 Antisense
ACGAGGCGTCGTCAAAGTTTCAGGA 423 93 558 Antisense
CATTTCCCGGCTTGTCGATGGTGGG 428 211 588 Antisense
TCCACAGGCCTTCTTGGTGTTAATG 700 585 622 Antisense
TGATGGTCGCCAATGCTCATAACTT 104 567 686 Antisense
GAAACACACTGTCACGAGGACCGTC 429 355 740 Antisense
GAGGACCGTCACAACAAGGAACACC 11 405 755 Antisense
CGAACGCCAGTGAGATGTCGGCCGC 5 253 779 Antisense
CTACAGGTGGAATTCAGCGCCCGAT 364 227 815 Antisense
GAAGCTCCGACGGCAGTTATCATCC 689 341 851 Antisense
Sequence Source Affymetrix Proprietary Database