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[193692_s_at] ER lumen protein retaining receptor

Description F09B9.3 /REP_DB=WormBase Gene ID /WP=CE23635 /GEN=erd-2 /TR=SW:P48583 /GB=CAA90056.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=ER lumen protein retaining receptor
Cluster 6grp_highest_10_10 > 06      6grp_high1_10_10 > 60      4grp_highest_8_8 > 02      4grp_high_8_8 > 46      6grp_highest_nonorm > 34      6grp_total > 50      4grp_total > 49      6grp_highest_sub > 04      6grp_cgc > 84      6grp_high1_sub > 04      6grp_cgc_sub > 04      6grp_total_sub > Hat      4grp_rule_based > L2      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 2242
1 2 3 4 range
A 1689.1
(-3)
P 		3885.6
(3)
P 		3092.3
(0.8)
P 		2572.8
(-0.6)
P 		2197
B 1756.6
(-3)
P 		3589.6
(2.7)
P 		3674.2
(3)
P 		1955.6
(-2.4)
P 		1918
C 1777.7
(-2.5)
P 		3136.6
(2.9)
P 		3160.8
(3)
P 		1643.7
(-3)
P 		1517
avr 1741.1
(-3) 		3537.3
(3) 		3309.1
(2.2) 		2057.4
(-1.9) 		1796

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2544
1 2 3 4 5 6 range
A 2920.3
(0.8)
P 		2706.5
(0.2)
P 		3806.6
(3)
P 		3417.9
(2)
P 		2594.6
(-0.1)
P 		1424.4
(-3)
P 		2382
B 2767.5
(0.1)
P 		2663.1
(-0.2)
P 		3125.8
(1)
P 		3968.1
(3)
P 		2425.2
(-0.7)
P 		1487.3
(-3)
P 		2481
C 2741.6
(0.5)
P 		2598.3
(0.1)
P 		2832
(0.8)
P 		3536.1
(3)
P 		2190.6
(-1.2)
P 		1613.6
(-3)
P 		1923
avr 2809.8
(0.7) 		2656
(0.2) 		3254.8
(1.9) 		3640.7
(3) 		2403.5
(-0.5) 		1508.4
(-3) 		2132
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 824
1 2 3 4 range
A 615
(0.1)
P 		843.5
(3)
P 		808.4
(2.5)
P 		376.6
(-3)
P 		467
B 560.2
(-1.2)
P 		886.5
(3)
P 		851.4
(2.6)
P 		416.7
(-3)
P 		470
C 588.5
(-0.7)
P 		901.8
(1.5)
P 		1101.6
(3)
P 		277.2
(-3)
P 		824
avr 587.9
(-0.5) 		877.3
(2.5) 		920.5
(3) 		356.8
(-3) 		564

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 704
1 2 3 4 5 6 range
A 538.3
(-1.1)
P 		962.6
(3)
P 		829
(1.7)
P 		866.9
(2.1)
P 		782.9
(1.2)
P 		346.8
(-3)
P 		616
B 963
(1.9)
P 		886.4
(1)
P 		759
(-0.5)
P 		1051
(3)
P 		985.3
(2.2)
P 		554.6
(-3)
P 		496
C 1016.2
(3)
P 		792.8
(0.2)
P 		720.8
(-0.7)
P 		711.1
(-0.8)
P 		708.8
(-0.9)
P 		540.2
(-3)
P 		476
avr 839.2
(2.4) 		880.6
(3) 		769.6
(1.3) 		876.3
(2.9) 		825.7
(2.2) 		480.5
(-3) 		400
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193692_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.16651
Sequence Type Exemplar sequence
Representative Public ID F09B9.3 NCBI
Target Description F09B9.3 /REP_DB=WormBase Gene ID /WP=CE23635 /GEN=erd-2 /TR=SW:P48583 /GB=CAA90056.2 /SUBMIT=HINXTON /CHR=X /FEA=Sanger Annotation /DEF=ER lumen protein retaining receptor
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_077302(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_077302 NCBI Caenorhabditis elegans ERD (yeast endoplasmic reticulum retention defective) related family member (erd-2) (erd-2) mRNA, complete cds. 11/11 A 
GENEFINDER00000037098 ENSEMBL cdna:GeneFinder chromosome:CEL140:X:10156911:10158670:-1 11/11 None
SNAP00000037097 ENSEMBL cdna:SNAP chromosome:CEL140:X:10157385:10158670:-1 11/11 None
F09B9.3 ENSEMBL cdna:known chromosome:CEL140:X:10156799:10160367:-1 gene:F09B9.3 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrX:10157135-10158670(-) 100.0 100.0
Public Domain and Genome References
Gene Title ER lumen protein retaining receptor
Gene Symbol erd-2
Ensembl F09B9.3
Entrez Gene 181228 Entrez gene
WormBase CE23635 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:260897_AT ER lumen protein retaining receptor (ERD2) / HDEL receptor at
ATGENOME1:18681_AT ER lumen protein retaining receptor (ERD2) / HDEL receptor at
CANINE_2:CFA.17420.1.S1_AT similar to KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (predicted) cfa
CANINE_2:CFA.18703.1.S1_S_AT similar to KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (predicted) cfa
CANINE_2:CFAAFFX.6938.1.S1_AT similar to KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (predicted) cfa
DROSOPHILA_2:1641295_S_AT KDEL receptor dm
DROSGENOME1:153581_AT KDEL receptor dm
HG-U133_PLUS_2:200922_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
HG-U133A:200922_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
HG-FOCUS:200922_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
HG-U133A_2:200922_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
HG-U95AV2:37386_I_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
HUGENEFL:X55885_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
U133_X3P:G5803047_3P_X_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
U133_X3P:G5803047_3P_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
U133_X3P:HS2.78040.2.S1_3P_A_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
HG-U133_PLUS_2:1555575_A_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
HG-U95AV2:37387_R_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
HG-U95D:75231_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 hs
MU11KSUBA:AA212981_S_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 mm
MU11KSUBB:MSA.8345.0_S_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 mm
MU11KSUBB:MSA.18482.0_S_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 mm
MG-U74AV2:95490_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 mm
MOE430A:1460211_A_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 mm
MOUSE430A_2:1460211_A_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 mm
MOUSE430_2:1460211_A_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 mm
MU19KSUBA:TC18417_S_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (Kdelr1), mRNA mm
RG-U34C:RC_AI230458_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (predicted) rn
RAE230A:1371514_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (predicted) rn
RAT230_2:1371514_AT KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 (predicted) rn
YEAST_2:1779835_AT Integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
15031 protein transport inferred from electronic annotation QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
16021 integral to membrane inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4872 receptor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA90056 Hypothetical protein F09B9.3 [Caenorhabditis elegans] ref|NP_509703.1| ERD (yeast endoplasmic reticulum retention defective) related family member (erd-2) [Caenorhabditis elegans] sp|P48583|ERD2_CAEEL ER lumen protein retaining receptor gb|AAC31954.1| ER lumen protein retaining receptor [Caenorhabditis elegans] 1.0E-118
blast C89623 protein F09B9.3 [imported] - Caenorhabditis elegans 1.0E-115
blast CAA90056 Hypothetical protein F09B9.3 [Caenorhabditis elegans] ref|NP_509703.1| ERD (yeast endoplasmic reticulum retention defective) related family member (erd-2) [Caenorhabditis elegans] sp|P48583|ERD2_CAEEL ER lumen protein retaining receptor gb|AAC31954.1| ER lumen protein retaining receptor [Caenorhabditis elegans] 1.0E-112
blast C89623 protein F09B9.3 [imported] - Caenorhabditis elegans 1.0E-111
blast CAA90056 Hypothetical protein F09B9.3 [Caenorhabditis elegans] ref|NP_509703.1| ERD (yeast endoplasmic reticulum retention defective) related family member (erd-2) [Caenorhabditis elegans] sp|P48583|ERD2_CAEEL ER lumen protein retaining receptor gb|AAC31954.1| ER lumen protein retaining receptor [Caenorhabditis elegans] 1.0E-111
blast CAE70531 Hypothetical protein CBG17162 [Caenorhabditis briggsae] 1.0E-107
Protein Domains
Database ID Description E-Value
Pfam IPR000133 EMBL-EBI ER lumen protein retaining receptor 1.0E-126
Trans Membrane
ID Number Of Domains Domain Boundaries
NP_509703.1 5 58-80,93-115,119-138,151-168,178-200
F09B9.3 5 58-80,93-115,119-138,151-168,178-200
GENEFINDER00000037098 5 58-80,93-115,119-138,151-168,178-200
SNAP00000037097 5 58-80,93-115,119-138,151-168,178-200
Sequence
Target Sequence 
>C. ELEGANS:193692_S_AT
ccatcgttgttcttctgcttaaaatatggaagtcacgcagttgcgaaggaatttctggtc
ggtcccaactgctttttgctctcgtctttgtaaccagatacttggatctcttcactaact
tcttttccttttacaacactgcgatgaagatcttctaccttgttgcatcatttggaaccg
tatacttgatgtgggcaaagtttaaggcaacctacgacagaaataacgattcttttcgta
ttgagttcttggttattccaagtatgatcctcgcactgctcatcaaccacgagtttatct
tcatggaggttatgtggacattctccatctatttggaagctgtcgccattatgccacaac
ttttcatgctttctcggactggaaatgcggaaactatcactgctcattatctctttgcac
tcgggtcatacagattcctctacattctcaactgggtctacagatactacactgagagct
tcttcgacccaatttcggttgttgctggaatcgtgcaaaccgttctctacgc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
CCATCGTTGTTCTTCTGCTTAAAAT 370 271 56 Antisense
TTTTGCTCTCGTCTTTGTAACCAGA 586 677 129 Antisense
GGATCTCTTCACTAACTTCTTTTCC 147 511 159 Antisense
TTCTTTTCCTTTTACAACACTGCGA 514 689 175 Antisense
AGATCTTCTACCTTGTTGCATCATT 58 67 203 Antisense
TTGGAAGCTGTCGCCATTATGCCAC 313 709 388 Antisense
CTATCACTGCTCATTATCTCTTTGC 284 225 449 Antisense
GCACTCGGGTCATACAGATTCCTCT 46 317 472 Antisense
ATTCCTCTACATTCTCAACTGGGTC 245 9 489 Antisense
TCGACCCAATTTCGGTTGTTGCTGG 566 601 539 Antisense
GAATCGTGCAAACCGTTCTCTACGC 113 329 563 Antisense
Sequence Source Affymetrix Proprietary Database