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[193666_at] F-actin capping protein beta subunit

Description M106.5 /REP_DB=WormBase Gene ID /WP=CE01608 /GEN=cap-2 /TR=SW:P34686 /GB=CAA87051.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=F-actin capping protein beta subunit
Cluster 6grp_highest_10_10 > 10      6grp_high1_10_10 > 09      4grp_highest_8_8 > 39      4grp_high_8_8 > 12      6grp_highest_nonorm > 13      6grp_total > 04      4grp_total > 20      6grp_cgc > 41      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 1450
1 2 3 4 range
A 2851.9
(1.4)
P 		2455
(-1.9)
P 		2326.9
(-3)
P 		3034.8
(3)
P 		708
B 2344.3
(-1.1)
P 		2484.4
(-0.5)
P 		1891.6
(-3)
P 		3341.8
(3)
P 		1450
C 2345
(-3)
P 		2389.3
(-2.3)
P 		2348.7
(-2.9)
P 		2730.8
(3)
P 		386
avr 2513.7
(-0.7) 		2442.9
(-1.2) 		2189.1
(-3) 		3035.8
(3) 		847

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1569
1 2 3 4 5 6 range
A 3289.6
(2.8)
P 		3320.8
(3)
P 		2101.2
(-3)
P 		2802.6
(0.5)
P 		2705.7
(-0)
P 		2096.7
(-3)
P 		1224
B 3194
(3)
P 		3015.4
(2.1)
P 		2048.1
(-3)
P 		3124.5
(2.6)
P 		3073.8
(2.4)
P 		2078.4
(-2.8)
P 		1146
C 3616.9
(3)
P 		2928.2
(-0.1)
P 		2856.1
(-0.4)
P 		2772.9
(-0.8)
P 		2676.6
(-1.2)
P 		2274.9
(-3)
P 		1342
avr 3366.8
(3) 		3088.1
(1.6) 		2335.1
(-2.1) 		2900
(0.7) 		2818.7
(0.3) 		2150
(-3) 		1217
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 600
1 2 3 4 range
A 1038.4
(3)
P 		532.9
(-2.1)
P 		608.3
(-1.3)
P 		444.2
(-3)
P 		594
B 747.6
(3)
P 		613.6
(0.4)
P 		438.3
(-3)
P 		712.1
(2.3)
P 		309
C 776.3
(2.3)
P 		686.9
(0.8)
P 		818.6
(3)
P 		460.5
(-3)
P 		358
avr 854.1
(3) 		611.1
(-1.6) 		621.7
(-1.4) 		538.9
(-3) 		315

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 883
1 2 3 4 5 6 range
A 606.4
(-1.8)
P 		1181
(3)
P 		457.6
(-3)
P 		710.8
(-0.9)
P 		816.5
(-0)
P 		510.5
(-2.6)
P 		723
B 1111.4
(1.9)
P 		1003.7
(1)
P 		497.3
(-3)
P 		827.6
(-0.4)
P 		1248.8
(3)
P 		775
(-0.8)
P 		752
C 1340.6
(3)
P 		893.5
(-0.4)
P 		726.9
(-1.7)
P 		557.6
(-3)
P 		866.1
(-0.6)
P 		761.5
(-1.4)
P 		783
avr 1019.5
(2.9) 		1026.1
(3) 		560.6
(-3) 		698.7
(-1.2) 		977.1
(2.4) 		682.3
(-1.4) 		466
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193666_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.4002
Sequence Type Exemplar sequence
Representative Public ID M106.5 NCBI
Target Description M106.5 /REP_DB=WormBase Gene ID /WP=CE01608 /GEN=cap-2 /TR=SW:P34686 /GB=CAA87051.1 /SUBMIT=HINXTON /CHR=2 /FEA=Sanger Annotation /DEF=F-actin capping protein beta subunit
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_063935(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_063935 NCBI Caenorhabditis elegans CAP-z protein family member (cap-2) (cap-2) mRNA, complete cds. 11/11 A 
SNAP00000018722 ENSEMBL cdna:SNAP chromosome:CEL140:II:10869226:10870326:1 11/11 None
GENEFINDER00000018731 ENSEMBL cdna:GeneFinder chromosome:CEL140:II:10869142:10870326:1 11/11 None
M106.5 ENSEMBL cdna:known chromosome:CEL140:II:10869100:10870710:1 gene:M106.5 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrII:10869188-10870323(+) 99.75 99.75
Public Domain and Genome References
Gene Title F-actin capping protein beta subunit
Gene Symbol cap-2
Ensembl M106.5
Entrez Gene 174673 Entrez gene
SwissProt P34686 EMBL-EBI
WormBase CE01608 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:261512_AT F-actin capping protein beta subunit family protein at
CANINE_2:CFA.1044.1.S1_AT similar to F-actin capping protein beta subunit cfa
CANINE_2:CFAAFFX.23315.1.S1_S_AT similar to F-actin capping protein beta subunit cfa
DROSOPHILA_2:1630572_AT capping protein beta dm
DROSGENOME1:141707_AT capping protein beta dm
CHICKEN:GGA.4050.2.S1_A_AT capping protein (actin filament) muscle Z-line, beta gga
HG-U133_PLUS_2:215097_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133A_2:215097_AT capping protein (actin filament) muscle Z-line, beta hs
HG-FOCUS:215097_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133A:215097_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133A_2:201950_X_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133A:201950_X_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133_PLUS_2:201950_X_AT capping protein (actin filament) muscle Z-line, beta hs
HU35KSUBC:RC_N98494_AT capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:G4826658_3P_S_AT capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:HS.76368.1.S1_3P_AT capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:HS.76368.0.S2_3P_S_AT capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:201949_3P_X_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133A_2:201949_X_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133_PLUS_2:201949_X_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133A:201949_X_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133A_2:37012_AT capping protein (actin filament) muscle Z-line, beta hs
HG-FOCUS:37012_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133_PLUS_2:37012_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U133A:37012_AT capping protein (actin filament) muscle Z-line, beta hs
HG-U95AV2:37012_AT capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:HS.301153.0.S1_3P_AT Capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:HS.176496.0.A1_3P_AT Capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:4901305_3P_S_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U133_PLUS_2:232949_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U133B:232949_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U133_PLUS_2:242066_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U133B:242066_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U95D:85947_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U133_PLUS_2:238351_X_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U133B:238351_X_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U133_PLUS_2:238352_S_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U133B:238352_S_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U133_PLUS_2:238388_X_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U133B:238388_X_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U95E:72427_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U95E:79967_AT Capping protein (actin filament) muscle Z-line, beta hs
HG-U95E:90223_F_AT Capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:238351_3P_X_AT Capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:238388_3P_X_AT Capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:HS.133296.0.S1_3P_A_AT Capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:HS.133296.0.S1_3P_S_AT Capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:HS.133296.1.A1_3P_A_AT Capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:HS.133296.1.S1_3P_A_AT Capping protein (actin filament) muscle Z-line, beta hs
U133_X3P:HS.133296.1.S1_3P_S_AT Capping protein (actin filament) muscle Z-line, beta hs
MU11KSUBA:U10406_F_AT capping protein (actin filament) muscle Z-line, beta mm
MU11KSUBB:MSA.15385.0_F_AT capping protein (actin filament) muscle Z-line, beta mm
MU11KSUBB:MSA.1333.0_F_AT capping protein (actin filament) muscle Z-line, beta mm
MU11KSUBB:MSA.23546.0_F_AT capping protein (actin filament) muscle Z-line, beta mm
MG-U74AV2:95142_S_AT capping protein (actin filament) muscle Z-line, beta mm
MG-U74AV2:161329_F_AT capping protein (actin filament) muscle Z-line, beta mm
MG-U74CV2:171104_I_AT capping protein (actin filament) muscle Z-line, beta mm
MOE430A:1453960_A_AT capping protein (actin filament) muscle Z-line, beta mm
MOUSE430A_2:1453960_A_AT capping protein (actin filament) muscle Z-line, beta mm
MOUSE430_2:1453960_A_AT capping protein (actin filament) muscle Z-line, beta mm
MOE430A:1431668_AT capping protein (actin filament) muscle Z-line, beta mm
MOUSE430A_2:1431668_AT capping protein (actin filament) muscle Z-line, beta mm
MOUSE430_2:1431668_AT capping protein (actin filament) muscle Z-line, beta mm
MOE430A:1417259_A_AT capping protein (actin filament) muscle Z-line, beta mm
MOUSE430A_2:1417259_A_AT capping protein (actin filament) muscle Z-line, beta mm
MOUSE430_2:1417259_A_AT capping protein (actin filament) muscle Z-line, beta mm
MG-U74AV2:95141_AT capping protein (actin filament) muscle Z-line, beta mm
MU19KSUBB:TC26589_AT Capping protein (actin filament) muscle Z-line, beta, mRNA (cDNA clone MGC:6082 IMAGE:3590980) mm
MU19KSUBB:TC26590_F_AT Capping protein (actin filament) muscle Z-line, beta, mRNA (cDNA clone MGC:6082 IMAGE:3590980) mm
MU19KSUBB:TC26590_I_AT Capping protein (actin filament) muscle Z-line, beta, mRNA (cDNA clone MGC:6082 IMAGE:3590980) mm
MU19KSUBC:TC39614_F_AT Capping protein (actin filament) muscle Z-line, beta, mRNA (cDNA clone MGC:6082 IMAGE:3590980) mm
MU19KSUBC:TC39614_I_AT Capping protein (actin filament) muscle Z-line, beta, mRNA (cDNA clone MGC:6082 IMAGE:3590980) mm
MU19KSUBC:TC39615_F_AT Capping protein (actin filament) muscle Z-line, beta, mRNA (cDNA clone MGC:6082 IMAGE:3590980) mm
MU19KSUBC:TC39615_I_AT Capping protein (actin filament) muscle Z-line, beta, mRNA (cDNA clone MGC:6082 IMAGE:3590980) mm
RG-U34C:RC_AI232101_AT F-actin capping protein beta subunit rn
RG-U34C:RC_AI171273_AT F-actin capping protein beta subunit rn
RAE230A:1399091_AT F-actin capping protein beta subunit rn
RAT230_2:1399091_AT F-actin capping protein beta subunit rn
RAE230B:1381494_AT F-actin capping protein beta subunit rn
RAT230_2:1381494_AT F-actin capping protein beta subunit rn
YEAST_2:1772418_AT Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
30036 actin cytoskeleton organization and biogenesis inferred from electronic annotation QuickGO AmiGO
30036 actin cytoskeleton organization and biogenesis inferred from direct assay QuickGO AmiGO
GO Cellular Component (view graph)
ID Description Evidence Links
8290 F-actin capping protein complex inferred from electronic annotation QuickGO AmiGO
5737 cytoplasm inferred from direct assay QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3779 actin binding inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA87051 Hypothetical protein M106.5 [Caenorhabditis elegans] emb|CAA79306.1| capping protein beta subunit [Caenorhabditis elegans] emb|CAA79270.1| capping protein beta subunit [Caenorhabditis elegans] ref|NP_496336.1| CAP-z protein family member (cap-2) [Caenorhabditis elegans] sp|P34686|CAPZB_CAEEL F-actin capping protein beta subunit 1.0E-156
blast AAY54264 F-actin capping protein beta subunit [Caenorhabditis remanei] 1.0E-153
blast CAE59593 Hypothetical protein CBG03000 [Caenorhabditis briggsae] 1.0E-152
blast AAY54264 F-actin capping protein beta subunit [Caenorhabditis remanei] 1.0E-152
blast CAA87051 Hypothetical protein M106.5 [Caenorhabditis elegans] emb|CAA79306.1| capping protein beta subunit [Caenorhabditis elegans] emb|CAA79270.1| capping protein beta subunit [Caenorhabditis elegans] ref|NP_496336.1| CAP-z protein family member (cap-2) [Caenorhabditis elegans] sp|P34686|CAPZB_CAEEL F-actin capping protein beta subunit 1.0E-149
Protein Domains
Database ID Description E-Value
Pfam IPR001698 EMBL-EBI F-actin capping protein, beta subunit 1.0E-126
Pfam IPR001698 EMBL-EBI F-actin capping protein, beta subunit 1.0E-126
Pfam IPR001698 EMBL-EBI F-actin capping protein, beta subunit 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:193666_AT
ggagtaatacctatgatccaccactcgaggatggacaattgccatcggaaaagcgcagaa
aaatggaaatcgaggcaaatgccgcttttgagtcataccgtgatttatacttcgagggag
gcgtctcatcagtttacttctgggacttggataatggaggtttcgccggaattgtgctca
tcaagaaagagggagacggagccaaaaatataacaggatgttgggattctattcacgtta
ttgagatcacggaaagagcacgccaggctcactacaagctcacctccactatcatgctgt
ggctgcagacaaacaaaagctccagcggtgtgatgaacctcggtggctcccttacaagac
agcatgagatggatgcaccaatcaacgatcagaacacacacttggctaatatgggacgaa
tgattgaggatcaggagtcgaaaatgcgtctgacgatcaatgagatatactttggaaaga
cgaagaaggtgatgtcggatctccgttcaaca

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GGAGTAATACCTATGATCCACCACT 550 513 236 Antisense
ATGCCGCTTTTGAGTCATACCGTGA 553 41 314 Antisense
GGCGTCTCATCAGTTTACTTCTGGG 557 541 355 Antisense
GAGGTTTCGCCGGAATTGTGCTCAT 357 403 392 Antisense
GGATGTTGGGATTCTATTCACGTTA 56 515 451 Antisense
GGAAAGAGCACGCCAGGCTCACTAC 700 525 486 Antisense
CTCACCTCCACTATCATGCTGTGGC 698 227 514 Antisense
AGCGGTGTGATGAACCTCGGTGGCT 544 79 559 Antisense
GTGGCTCCCTTACAAGACAGCATGA 651 491 578 Antisense
AACGATCAGAACACACACTTGGCTA 24 145 619 Antisense
GGTGATGTCGGATCTCCGTTCAACA 109 501 723 Antisense
Sequence Source Affymetrix Proprietary Database