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[193663_s_at] dihydroxypolyprenylbenzoate methyltransferase

Description Y57G11C.11 /REP_DB=WormBase Gene ID /WP=CE14946 /TR=O18235 /GB=CAB16512.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=dihydroxypolyprenylbenzoate methyltransferase
Cluster 6grp_highest_10_10 > 01      6grp_high1_10_10 > 0      4grp_highest_8_8 > 05      4grp_high_8_8 > 29      6grp_highest_nonorm > 51      6grp_total > 09      4grp_total > 26      6grp_cgc > 0      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 237
1 2 3 4 range
A 676.8
(0.1)
P 		716.7
(1.7)
P 		597.3
(-3)
P 		748.9
(3)
P 		152
B 566.9
(-3)
P 		595.6
(-1.3)
P 		669.6
(3)
P 		620.9
(0.2)
P 		103
C 511.7
(-3)
P 		695.8
(3)
P 		523.7
(-2.6)
P 		660
(1.8)
P 		184
avr 585.1
(-3) 		669.4
(2.5) 		596.9
(-2.2) 		676.6
(3) 		92

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 319
1 2 3 4 5 6 range
A 785.7
(3)
P 		538.6
(-2.2)
P 		657.6
(0.3)
P 		660.7
(0.4)
P 		610.2
(-0.7)
P 		498.8
(-3)
P 		287
B 742.2
(3)
P 		525.3
(-1.9)
P 		592.9
(-0.4)
P 		580.7
(-0.7)
P 		578.8
(-0.7)
P 		478.7
(-3)
P 		264
C 590.8
(-0.7)
P 		553.9
(-1.4)
P 		581.9
(-0.8)
P 		786
(3)
P 		488.1
(-2.6)
P 		467.3
(-3)
P 		319
avr 706.2
(3) 		539.3
(-1.5) 		610.8
(0.5) 		675.8
(2.2) 		559
(-0.9) 		481.6
(-3) 		225
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 137
1 2 3 4 range
A 246.4
(3)
P 		155.6
(-1)
P 		156.2
(-1)
P 		109.6
(-3)
P 		137
B 180.8
(3)
P 		147.1
(-1.2)
P 		155.2
(-0.2)
P 		132.3
(-3)
P 		49
C 169.4
(0.9)
P 		200.1
(3)
P 		182.5
(1.8)
P 		111.3
(-3)
P 		89
avr 198.9
(3) 		167.6
(0.7) 		164.6
(0.5) 		117.7
(-3) 		81

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 137
1 2 3 4 5 6 range
A 144.8
(-1)
P 		191.6
(3)
P 		143.2
(-1.1)
P 		167.6
(0.9)
P 		184.1
(2.4)
P 		121.4
(-3)
P 		70
B 258.3
(3)
P 		174.9
(-1.4)
P 		144
(-3)
P 		153.8
(-2.5)
P 		235.1
(1.8)
P 		178.5
(-1.2)
P 		114
C 219
(3)
P 		169
(-1.2)
P 		148.1
(-3)
P 		158.1
(-2.2)
P 		158
(-2.2)
P 		156.4
(-2.3)
P 		71
avr 207.4
(3) 		178.5
(0.2) 		145.1
(-3) 		159.8
(-1.6) 		192.4
(1.6) 		152.1
(-2.3) 		62
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193663_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9183
Sequence Type Exemplar sequence
Representative Public ID Y57G11C.11 NCBI
Target Description Y57G11C.11 /REP_DB=WormBase Gene ID /WP=CE14946 /TR=O18235 /GB=CAB16512.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=dihydroxypolyprenylbenzoate methyltransferase
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_070388(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_070388 NCBI Caenorhabditis elegans COenzyme Q (ubiquinone) biosynthesis family member (coq-3) (coq-3) mRNA, complete cds. 11/11 None
GENEFINDER00000003588 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:14791100:14796286:-1 11/11 None
Y57G11C.11 ENSEMBL cdna:known chromosome:CEL140:IV:14793081:14796337:-1 gene:Y57G11C.11 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000003477 5/11 Cross Hyb Matching Probes None
SNAP00000003478 6/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:14793177-14796292(-) 100.0 100.0
Public Domain and Genome References
Gene Title dihydroxypolyprenylbenzoate methyltransferase
Gene Symbol coq-3
Ensembl Y57G11C.11
Entrez Gene 178403 Entrez gene
SwissProt O18235 EMBL-EBI
WormBase CE14946 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATGENOME1:13984_G_AT hexaprenyldihydroxybenzoate methyltransferase at
ATGENOME1:13983_AT hexaprenyldihydroxybenzoate methyltransferase at
ATH1-121501:267210_AT hexaprenyldihydroxybenzoate methyltransferase at
CANINE_2:CFA.19331.1.S1_AT coenzyme Q3 homolog, methyltransferase (yeast) cfa
CANINE_2:CFAAFFX.6146.1.S1_AT coenzyme Q3 homolog, methyltransferase (yeast) cfa
CANINE_2:CFAAFFX.6146.1.S1_S_AT coenzyme Q3 homolog, methyltransferase (yeast) cfa
DROSOPHILA_2:1627050_AT dm
DROSGENOME1:141494_AT dm
CHICKEN:GGA.11388.1.S1_AT coenzyme Q3 homolog, methyltransferase (yeast) gga
CHICKEN:GGAAFFX.20190.1.S1_AT Coenzyme Q3 homolog, methyltransferase (yeast) gga
HG-U133_PLUS_2:221227_X_AT coenzyme Q3 homolog, methyltransferase (yeast) hs
HG-U133A:221227_X_AT coenzyme Q3 homolog, methyltransferase (yeast) hs
HG-FOCUS:221227_X_AT coenzyme Q3 homolog, methyltransferase (yeast) hs
HG-U133A_2:221227_X_AT coenzyme Q3 homolog, methyltransferase (yeast) hs
HG-U133_PLUS_2:223515_S_AT coenzyme Q3 homolog, methyltransferase (yeast) hs
HG-U133B:223515_S_AT coenzyme Q3 homolog, methyltransferase (yeast) hs
U133_X3P:G12052970_3P_S_AT coenzyme Q3 homolog, methyltransferase (yeast) hs
U133_X3P:G12052970_3P_AT coenzyme Q3 homolog, methyltransferase (yeast) hs
U133_X3P:223515_3P_S_AT coenzyme Q3 homolog, methyltransferase (yeast) hs
HG-U95E:88452_AT coenzyme Q3 homolog, methyltransferase (yeast) hs
MG-U74AV2:99365_AT coenzyme Q3 homolog, methyltransferase (yeast) mm
MU11KSUBA:C78422_RC_AT coenzyme Q3 homolog, methyltransferase (yeast) mm
MG-U74BV2:105230_AT coenzyme Q3 homolog, methyltransferase (yeast) mm
MOE430A:1437364_AT coenzyme Q3 homolog, methyltransferase (yeast) mm
MOUSE430A_2:1437364_AT coenzyme Q3 homolog, methyltransferase (yeast) mm
MOUSE430_2:1437364_AT coenzyme Q3 homolog, methyltransferase (yeast) mm
MOE430A:1436351_AT coenzyme Q3 homolog, methyltransferase (yeast) mm
MOUSE430A_2:1436351_AT coenzyme Q3 homolog, methyltransferase (yeast) mm
MOUSE430_2:1436351_AT coenzyme Q3 homolog, methyltransferase (yeast) mm
MG-U74CV2:171413_AT Coenzyme Q3 homolog, methyltransferase (yeast), mRNA (cDNA clone MGC:74049 IMAGE:30312962) mm
MU19KSUBC:TC41802_AT Coenzyme Q3 homolog, methyltransferase (yeast), mRNA (cDNA clone MGC:74049 IMAGE:30312962) mm
RG-U34A:L20427_AT coenzyme Q3 homolog, methyltransferase (yeast) rn
RAE230A:1367818_AT coenzyme Q3 homolog, methyltransferase (yeast) rn
RAT230_2:1367818_AT coenzyme Q3 homolog, methyltransferase (yeast) rn
YEAST_2:1779936_AT O-methyltransferase, catalyzes two different O-methylation steps in ubiquinone (Coenzyme Q) biosynthesis; component of a mitochondrial ubiquinone-synthesizing complex Sc
Gene Ontology
GO Molecular Function (view graph)
ID Description Evidence Links
8168 methyltransferase activity inferred from sequence similarity QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB16511 Hypothetical protein Y57G11C.10 [Caenorhabditis elegans] ref|NP_502788.1| GDI (RabGDP Dissociation Inhibitor) family member (gdi-1) [Caenorhabditis elegans] gb|AAA17051.1| Guanine nucleotide dissociation inhibitor (GDI) for rab GTPase 0.0
blast CAE73908 Hypothetical protein CBG21516 [Caenorhabditis briggsae] 0.0
blast AAF52777 CG4422-PA [Drosophila melanogaster] ref|NP_523524.2| CG4422-PA [Drosophila melanogaster] gb|AAL39842.1| LD46767p [Drosophila melanogaster] gb|AAO39567.1| LP03430p [Drosophila melanogaster] 1.0E-166
blast CAB16512 Hypothetical protein Y57G11C.11 [Caenorhabditis elegans] ref|NP_502789.1| COenzyme Q (ubiquinone) biosynthesis family member (coq-3) [Caenorhabditis elegans] 1.0E-147
blast CAE73907 Hypothetical protein CBG21513 [Caenorhabditis briggsae] 1.0E-112
blast XP_419824 PREDICTED: similar to Hexaprenyldihydroxybenzoate methyltransferase, mitochondrial precursor (Dihydroxyhexaprenylbenzoate methyltransferase) (3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase) (DHHB methyltransferase) (DHHB-MT) (DHHB-MTase)... [Gallus gallus] 4.0E-48
Protein Domains
Database ID Description E-Value
Pfam IPR002005 EMBL-EBI Rab GTPase activator 1.0E-126
Sequence
Target Sequence 
>C. ELEGANS:193663_S_AT
aaaagcgatcagaaggctcctcctcgattagtggacgttggaagcggagggggtcttttg
tcgattccactggccagaagtggattcgatgttacaggaattgatgcgacgaagcaagct
gtagaagctgcgaatcagtccctcacagcgaaaccccttcaaattgccggaatctcgaag
cgcctccggttcgagcataccagcgtcgaggatttctgtcagaagccacacaataaatcg
gcctacgatgcagtcgtcgcttcggaaattgtcgaacacgtcgccgatcttcccggattc
attggctgcctcgctgagctggctcgccccggtgccccgctcttcatcacaactatcaac
agaacgtggctgagcaaattggcagctatttggcttgcagagaatgtactcaaaatcgtg
ccgcccggagtccacgactgggaaaaattcatcacacccgccgagctcacttcacatctc
gaaaa

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
AAAAGCGATCAGAAGGCTCCTCCTC 649 131 220 Antisense
CTCCTCCTCGATTAGTGGACGTTGG 333 233 236 Antisense
CTTTTGTCGATTCCACTGGCCAGAA 92 219 274 Antisense
TAGAAGCTGCGAATCAGTCCCTCAC 81 653 341 Antisense
TCACAGCGAAACCCCTTCAAATTGC 136 627 362 Antisense
GAGCATACCAGCGTCGAGGATTTCT 325 389 412 Antisense
TGCAGTCGTCGCTTCGGAAATTGTC 329 571 468 Antisense
GGAAATTGTCGAACACGTCGCCGAT 476 525 483 Antisense
CGCTCTTCATCACAACTATCAACAG 449 255 557 Antisense
AGAATGTACTCAAAATCGTGCCGCC 29 75 620 Antisense
CCGAGCTCACTTCACATCTCGAAAA 96 265 680 Antisense
Sequence Source Affymetrix Proprietary Database