[Home] | [Total List]

[193645_at] ubiquitin-conjugating enzyme E2-17 KD

Description M7.1 /REP_DB=WormBase Gene ID /WP=CE03482 /GEN=let-70 /TR=SW:P35129 /GB=CAA92745.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=ubiquitin-conjugating enzyme E2-17 KD
Cluster 6grp_highest_10_10 > 83      6grp_high1_10_10 > 48      4grp_highest_8_8 > 15      4grp_high_8_8 > 14      6grp_highest_nonorm > 48      6grp_total > 49      4grp_total > 10      6grp_highest_sub > Cu      6grp_cgc > 07      6grp_high1_sub > Cu      6grp_total_sub > Cup      4grp_rule_based > L4      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 4070
1 2 3 4 range
A 4854.2
(-3)
P 		5959.7
(-1.3)
P 		4834.1
(-3)
P 		8876.6
(3)
P 		4043
B 5260.3
(-3)
P 		5626.2
(-2.4)
P 		5874.1
(-2)
P 		8904.2
(3)
P 		3644
C 5478.2
(-2.1)
P 		5587.9
(-1.9)
P 		5069.8
(-3)
P 		7898.8
(3)
P 		2829
avr 5197.6
(-3) 		5724.6
(-2.1) 		5259.3
(-2.9) 		8559.9
(3) 		3362

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 2020
1 2 3 4 5 6 range
A 5316.5
(2.4)
P 		3913.7
(-1.7)
P 		4048.8
(-1.3)
P 		3491.1
(-3)
P 		4182.2
(-0.9)
P 		5510.9
(3)
P 		2020
B 4399.5
(1.8)
P 		3671.8
(-3)
P 		4573.4
(3)
P 		4207
(0.6)
P 		4110.1
(-0.1)
P 		4360.9
(1.6)
P 		902
C 5187.8
(3)
P 		3667.1
(-3)
P 		3859
(-2.2)
P 		4006.7
(-1.7)
P 		4251.5
(-0.7)
P 		4633.4
(0.8)
P 		1521
avr 4967.9
(3) 		3750.9
(-3) 		4160.4
(-1) 		3901.6
(-2.3) 		4181.3
(-0.9) 		4835.1
(2.3) 		1217
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 634
1 2 3 4 range
A 1767.4
(3)
P 		1293.7
(-2.6)
P 		1263.7
(-3)
P 		1299.4
(-2.6)
P 		504
B 1677.5
(0.5)
P 		1389.5
(-2.7)
P 		1361.2
(-3)
P 		1897.5
(3)
P 		536
C 1813.5
(3)
P 		1606.6
(0.4)
P 		1767
(2.4)
P 		1331.9
(-3)
P 		482
avr 1752.8
(3) 		1429.9
(-3) 		1464
(-2.4) 		1509.6
(-1.5) 		323

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 1117
1 2 3 4 5 6 range
A 980.1
(-1.8)
P 		1391.9
(3)
P 		881.7
(-3)
P 		885.4
(-3)
P 		1262
(1.5)
P 		1341.7
(2.4)
P 		510
B 1530.8
(1.5)
P 		1222.2
(-1.8)
P 		1110.6
(-3)
P 		1114.3
(-3)
P 		1669.9
(3)
P 		1626.2
(2.5)
P 		559
C 1922.9
(3)
P 		1118.9
(-1.3)
P 		982.2
(-2.1)
P 		805.7
(-3)
P 		1375.7
(0.1)
P 		1551.1
(1)
P 		1117
avr 1477.9
(2.7) 		1244.3
(0.2) 		991.5
(-2.4) 		935.1
(-3) 		1435.9
(2.3) 		1506.3
(3) 		571
NetAffx Links Cluster Members
Consensus/Exemplar
GeneChip Array Information
Probe Set ID 193645_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.9128
Sequence Type Exemplar sequence
Representative Public ID M7.1 NCBI
Target Description M7.1 /REP_DB=WormBase Gene ID /WP=CE03482 /GEN=let-70 /TR=SW:P35129 /GB=CAA92745.1 /SUBMIT=HINXTON /CHR=4 /FEA=Sanger Annotation /DEF=ubiquitin-conjugating enzyme E2-17 KD
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_069664(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_069664 NCBI Caenorhabditis elegans LEThal family member (let-70) (let-70) mRNA, complete cds. 11/11 None
SNAP00000010381 ENSEMBL cdna:SNAP chromosome:CEL140:IV:11081550:11082179:-1 11/11 None
GENEFINDER00000010391 ENSEMBL cdna:GeneFinder chromosome:CEL140:IV:11081550:11082179:-1 11/11 None
M7.1 ENSEMBL cdna:known chromosome:CEL140:IV:11081055:11082225:-1 gene:M7.1 11/11 A 
Annotation Notes
There are no noteworthy cross hybridizing mRNAs found for this probe set.
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrIV:11081555-11082185(-) 100.0 100.0
Public Domain and Genome References
Gene Title ubiquitin-conjugating enzyme E2-17 KD
Gene Symbol let-70
Ensembl M7.1
Entrez Gene 178006 Entrez gene
SwissProt P35129 EMBL-EBI
WormBase CE03482 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:253826_S_AT ubiquitin-conjugating enzyme 10 (UBC10) at
CANINE:1597600_AT similar to Ubiquitin-conjugating enzyme E2 D2 (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2) cfa
CANINE:1595537_AT similar to Ubiquitin-conjugating enzyme E2 D2 (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2) cfa
CANINE_2:CFA.19401.1.S1_AT similar to Ubiquitin-conjugating enzyme E2 D2 (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2) cfa
CANINE_2:CFA.19401.1.S1_S_AT similar to Ubiquitin-conjugating enzyme E2 D2 (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2) cfa
CANINE_2:CFA.4263.1.S1_AT similar to Ubiquitin-conjugating enzyme E2 D2 (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2) cfa
CANINE_2:CFAAFFX.9524.1.S1_S_AT similar to Ubiquitin-conjugating enzyme E2 D2 (Ubiquitin-protein ligase D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (E2(17)KB 2) cfa
DROSGENOME1:143638_AT effete dm
DROSOPHILA_2:1636436_AT effete dm
HG-U133_PLUS_2:201344_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133A:201344_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133A_2:201344_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U95AV2:832_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HC-G110:832_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133A:201345_S_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133_PLUS_2:201345_S_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133A_2:201345_S_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133A:201343_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133_PLUS_2:201343_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133A_2:201343_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-FOCUS:201343_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HU35KSUBB:RC_N57480_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HU35KSUBD:RC_H68221_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HUGENEFL:U39317_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
U133_X3P:G4507774_3P_A_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
U133_X3P:HS.108332.0.S3_3P_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
U133_X3P:HS.108332.0.S2_3P_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U95AV2:38705_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U95B:50909_AT ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133A_2:215604_X_AT Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133_PLUS_2:215604_X_AT Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133A:215604_X_AT Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133_PLUS_2:240139_AT Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133B:240139_AT Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U95E:71723_AT Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
U133_X3P:HS.221216.0.A1_3P_AT Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133_PLUS_2:210717_AT Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133A:210717_AT Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
HG-U133A_2:210717_AT Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) hs
MOE430A:1416475_AT ubiquitin-conjugating enzyme E2D 2 mm
MOUSE430A_2:1416475_AT ubiquitin-conjugating enzyme E2D 2 mm
MOUSE430_2:1416475_AT ubiquitin-conjugating enzyme E2D 2 mm
MOE430A:1416477_AT ubiquitin-conjugating enzyme E2D 2 mm
MOUSE430_2:1416477_AT ubiquitin-conjugating enzyme E2D 2 mm
MOUSE430A_2:1416477_AT ubiquitin-conjugating enzyme E2D 2 mm
MOE430A:1416476_A_AT ubiquitin-conjugating enzyme E2D 2 mm
MOUSE430A_2:1416476_A_AT ubiquitin-conjugating enzyme E2D 2 mm
MOUSE430_2:1416476_A_AT ubiquitin-conjugating enzyme E2D 2 mm
MOE430A:1448356_AT ubiquitin-conjugating enzyme E2D 2 mm
MOUSE430_2:1448356_AT ubiquitin-conjugating enzyme E2D 2 mm
MOUSE430A_2:1448356_AT ubiquitin-conjugating enzyme E2D 2 mm
MU11KSUBA:U62483_S_AT ubiquitin-conjugating enzyme E2D 2 mm
MG-U74AV2:93069_AT ubiquitin-conjugating enzyme E2D 2 mm
MG-U74AV2:162499_F_AT ubiquitin-conjugating enzyme E2D 2 mm
MG-U74CV2:170136_R_AT ubiquitin-conjugating enzyme E2D 2 mm
MOUSE430_2:1439655_AT Ubiquitin-conjugating enzyme E2D 2, mRNA (cDNA clone MGC:7285 IMAGE:3485259) mm
MOE430B:1439655_AT Ubiquitin-conjugating enzyme E2D 2, mRNA (cDNA clone MGC:7285 IMAGE:3485259) mm
MOE430B:1445885_AT Ubiquitin-conjugating enzyme E2D 2, mRNA (cDNA clone MGC:7285 IMAGE:3485259) mm
MOUSE430_2:1445885_AT Ubiquitin-conjugating enzyme E2D 2, mRNA (cDNA clone MGC:7285 IMAGE:3485259) mm
YEAST_2:1778788_AT Ubiquitin-conjugating enzyme that mediates degradation of short-lived and abnormal proteins; interacts with E3-CaM in ubiquitinating calmodulin; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6464 protein modification inferred from electronic annotation QuickGO AmiGO
6512 ubiquitin cycle inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
4840 ubiquitin conjugating enzyme activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAA92745 Hypothetical protein M7.1 [Caenorhabditis elegans] ref|NP_502065.1| LEThal family member (let-70) [Caenorhabditis elegans] gb|AAB25489.2| ubiquitin-conjugating enzyme [Caenorhabditis elegans] sp|P35129|UBC2_CAEEL Ubiquitin-conjugating enzyme E2 2 (Ubiquitin-protein ligase 2) (Ubiquitin carrier protein 2) emb|CAE61994.1| Hypothetical protein CBG06002 [Caenorhabditis briggsae] 6.0E-85
blast 1Z2U Chain , The 1.1a Crystallographic Structure Of Ubiquitin- Conjugating Enzyme (Ubc-2) From Caenorhabditis Elegans: Functional And Evolutionary Significance 6.0E-85
blast A48145 ubiquitin-conjugating enzyme ubc-2 - Caenorhabditis elegans 2.0E-84
Protein Domains
Database ID Description E-Value
Pfam IPR000608 EMBL-EBI Ubiquitin-conjugating enzymes 1.1E-81
Sequence
Target Sequence 
>C. ELEGANS:193645_AT
acaatgctccgctggaccagttggtgatgatttgttccattggcaagctacgattatggg
cccaccagagtctccctatcagggaggtgtcttcttcctcactatccacttcccaacaga
ctatccattcaaaccaccaaaggttgccttcaccactcgaatttatcatccgaacatcaa
ttcaaacggaagcatctgccttgacattctccgttcgcagtggtcgccggctctgaccat
ttcgaaagttctgctttcgatctgctcgctgctctgtgatccaaatccggatgatccact
tgtgccagagattgcacgcatctacaagacggatc

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
ACAATGCTCCGCTGGACCAGTTGGT 97 115 69 Antisense
ATCAGGGAGGTGTCTTCTTCCTCAC 610 29 146 Antisense
AACAGACTATCCATTCAAACCACCA 458 137 183 Antisense
TCAAACCACCAAAGGTTGCCTTCAC 680 627 197 Antisense
TGCCTTCACCACTCGAATTTATCAT 563 585 213 Antisense
TATCATCCGAACATCAATTCAAACG 495 659 232 Antisense
CGGAAGCATCTGCCTTGACATTCTC 190 243 255 Antisense
GGCTCTGACCATTTCGAAAGTTCTG 695 537 297 Antisense
AAATCCGGATGATCCACTTGTGCCA 669 117 351 Antisense
ACTTGTGCCAGAGATTGCACGCATC 207 103 366 Antisense
ATTGCACGCATCTACAAGACGGATC 514 5 379 Antisense
Sequence Source Affymetrix Proprietary Database