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[193644_s_at] translational initiation factor 2 beta subunit

Description K04G2.1 /REP_DB=WormBase Gene ID /WP=CE16227 /TR=SW:Q21230 /GB=CAB00049.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=translational initiation factor 2 beta subunit
Cluster 6grp_highest_10_10 > 05      6grp_high1_10_10 > 20      4grp_highest_8_8 > 19      4grp_high_8_8 > 63      6grp_highest_nonorm > 67      6grp_total > 50      4grp_total > 56      6grp_highest_sub > 03_04      6grp_total_sub > Hat      

Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 909
1 2 3 4 range
A 1972.6
(-0.5)
P 		1597.9
(-3)
P 		2506.4
(3)
P 		1982
(-0.5)
P 		909
B 1677.9
(-3)
P 		2038.4
(1)
P 		2221.5
(3)
P 		2091.4
(1.6)
P 		544
C 1887.3
(-1.1)
P 		2176.4
(1.3)
P 		2387
(3)
P 		1649.7
(-3)
P 		737
avr 1845.9
(-3) 		1937.6
(-2) 		2371.6
(3) 		1907.7
(-2.3) 		526

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 867
1 2 3 4 5 6 range
A 2070.3
(3)
P 		1721.8
(-0.2)
P 		1981.2
(2.2)
P 		2002.3
(2.4)
P 		1407.3
(-3)
P 		1593.8
(-1.3)
P 		663
B 1776.5
(-0.7)
P 		1786.2
(-0.6)
P 		2274.1
(3)
P 		1773.3
(-0.7)
P 		1514.3
(-2.6)
P 		1462.6
(-3)
P 		812
C 1927.5
(1.5)
P 		1779.6
(-0)
P 		1716.1
(-0.7)
P 		2068
(3)
P 		1495.2
(-3)
P 		1497.4
(-3)
P 		573
avr 1924.8
(2.2) 		1762.5
(0.4) 		1990.5
(3) 		1947.9
(2.5) 		1472.3
(-3) 		1517.9
(-2.5) 		518
No Scale
G range Absolute graph Relative graph Expression Table Dauer Comp.
4 554
1 2 3 4 range
A 718.2
(3)
P 		346.9
(-2.2)
P 		655.2
(2.1)
P 		290.1
(-3)
P 		428
B 535.1
(3)
P 		503.4
(0.9)
P 		514.8
(1.6)
P 		445.7
(-3)
P 		89
C 624.7
(0.8)
P 		625.7
(0.8)
P 		831.9
(3)
P 		278.2
(-3)
P 		554
avr 626
(2.2) 		492
(-0.2) 		667.3
(3) 		338
(-3) 		329

1 : 1 state (S1, L1)
2 : dauer (ST, LT)
6 333
1 2 3 4 5 6 range
A 381.6
(-3)
P 		612.4
(3)
P 		431.5
(-1.7)
P 		507.8
(0.3)
P 		424.7
(-1.9)
P 		388
(-2.8)
P 		231
B 618.1
(3)
P 		594.6
(2)
P 		552.2
(0.3)
P 		469.7
(-3)
P 		615.2
(2.9)
P 		545.4
(0.1)
P 		148
C 714.4
(3)
P 		543
(-0.4)
P 		436.8
(-2.6)
P 		415.9
(-3)
P 		483.8
(-1.6)
P 		501.3
(-1.3)
P 		299
avr 571.4
(2.4) 		583.3
(3) 		473.5
(-2.5) 		464.5
(-3) 		507.9
(-0.8) 		478.2
(-2.3) 		119
NetAffx Links Cluster Members
Consensus/Exemplar
Group Members
GeneChip Array Information
Probe Set ID 193644_s_at
GeneChip Array C. elegans Genome Array
Organism Common Name Nematode
Probe Design Information
Transcript ID(Array Design) affy.Ce.761
Sequence Type Exemplar sequence
Representative Public ID K04G2.1 NCBI
Target Description K04G2.1 /REP_DB=WormBase Gene ID /WP=CE16227 /TR=SW:Q21230 /GB=CAB00049.1 /SUBMIT=HINXTON /CHR=1 /FEA=Sanger Annotation /DEF=translational initiation factor 2 beta subunit
Cluster Evidence This cluster is supported by a Sanger Annotation.
Annotation Method Description
Annotation Description This probe set was annotated using the Matching Probes based pipeline to a RefSeq identifier using 1 transcript(s).
Annotation Grade This is a grade A annotation.
Annotation Transcript Cluster (# of Matching Probes) NM_059808(11)
Transcript Assignments
Representative
Transcript		 Description Matching Probes Related Probesets by Grade
NM_059808 NCBI Caenorhabditis elegans K04G2.1 (K04G2.1) mRNA, complete cds. 11/11 None
K04G2.1.1 ENSEMBL cdna:known chromosome:CEL140:I:8034732:8035918:-1 gene:K04G2.1 11/11 None
K04G2.1.2 ENSEMBL cdna:known chromosome:CEL140:I:8034801:8036878:-1 gene:K04G2.1 11/11 None
Annotation Notes
Cross Hybridizing mRNA Matched Probes Nature of Assignment Related Probesets by Grade
SNAP00000009068 5/11 Cross Hyb Matching Probes None
GENEFINDER00000009101 4/11 Cross Hyb Matching Probes None
GENEFINDER00000028910 4/11 Cross Hyb Matching Probes None
Genomic Alignment of Consensus/Exemplar Sequence
Assembly Wormbase March 2004
Alignment(s)
Position Identity Coverage Cytoband
chrI:8034846-8035819(-) 100.0 100.0
Public Domain and Genome References
Gene Title translational initiation factor 2 beta subunit
Ensembl K04G2.1
Entrez Gene 172584 Entrez gene
SwissProt Q21230 EMBL-EBI
WormBase CE16227 Wormbase
Functional Annotations
Ortholog
ID Title Organism
ATH1-121501:246192_AT eukaryotic translation initiation factor 2 subunit 2, putative / eIF-2-beta, putative at
CANINE:1601074_X_AT similar to Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 beta subunit) (eIF-2-beta) cfa
CANINE:1601073_AT similar to Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 beta subunit) (eIF-2-beta) cfa
CANINE:1586638_X_AT similar to Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 beta subunit) (eIF-2-beta) cfa
CANINE_2:CFA.304.1.A1_S_AT similar to Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 beta subunit) (eIF-2-beta) cfa
DROSOPHILA_2:1636176_AT Eukaryotic initiation factor 2 dm
DROSGENOME1:142531_AT Eukaryotic initiation factor 2 dm
CHICKEN:GGA.1487.1.S1_AT eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa gga
CHICKEN:GGA.1487.1.S2_AT eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa gga
HG-U133_PLUS_2:208726_S_AT eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa hs
HG-U133A:208726_S_AT eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa hs
HG-U133A_2:208726_S_AT eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa hs
HG-FOCUS:208726_S_AT eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa hs
HUGENEFL:M29536_AT eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa hs
U133_X3P:G12653382_3P_A_AT eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa hs
MOE430A:1417712_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430A_2:1417712_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430_2:1417712_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOE430A:1417713_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430_2:1417713_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430A_2:1417713_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOE430A:1448820_A_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430_2:1448820_A_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430A_2:1448820_A_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MG-U74AV2:160365_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430_2:1448819_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430A_2:1448819_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOE430A:1448819_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MG-U74AV2:97083_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430_2:1456617_A_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOE430A:1456617_A_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430A_2:1456617_A_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MU11KSUBA:AA544671_G_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MU11KSUBA:AA544671_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MU11KSUBA:AA600468_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MU11KSUBB:MSA.15780.0_F_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MU11KSUBB:MSA.4559.0_S_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MU11KSUBB:MSA.11506.0_F_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOE430A:1441023_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430A_2:1441023_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MOUSE430_2:1441023_AT eukaryotic translation initiation factor 2, subunit 2 (beta) mm
MU19KSUBC:TC39845_AT Eukaryotic translation initiation factor 2, subunit 2 (beta) (Eif2s2), mRNA mm
MU19KSUBC:TC39846_AT Eukaryotic translation initiation factor 2, subunit 2 (beta) (Eif2s2), mRNA mm
MU19KSUBC:TC39848_F_AT Eukaryotic translation initiation factor 2, subunit 2 (beta) (Eif2s2), mRNA mm
MU19KSUBC:TC41194_AT Eukaryotic translation initiation factor 2, subunit 2 (beta) (Eif2s2), mRNA mm
MU19KSUBC:TC41364_AT Eukaryotic translation initiation factor 2, subunit 2 (beta) (Eif2s2), mRNA mm
RG-U34B:RC_AA901338_AT eukaryotic translation initiation factor 2, subunit 2 (beta) rn
RAE230A:1374397_AT eukaryotic translation initiation factor 2, subunit 2 (beta) rn
RAT230_2:1374397_AT eukaryotic translation initiation factor 2, subunit 2 (beta) rn
RAE230A:1374721_AT Eukaryotic translation initiation factor 2, subunit 2 (beta) rn
RAT230_2:1374721_AT Eukaryotic translation initiation factor 2, subunit 2 (beta) rn
RG-U34B:RC_AA964681_AT Eukaryotic translation initiation factor 2, subunit 2 (beta) rn
RG-U34B:RC_AI070205_AT Eukaryotic translation initiation factor 2, subunit 2 (beta) rn
RG-U34C:RC_AI178647_AT Eukaryotic translation initiation factor 2, subunit 2 (beta) rn
YEAST_2:1774071_AT Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding Sc
Gene Ontology
GO Biological Process (view graph)
ID Description Evidence Links
6413 translational initiation inferred from electronic annotation QuickGO AmiGO
GO Molecular Function (view graph)
ID Description Evidence Links
3743 translation initiation factor activity inferred from electronic annotation QuickGO AmiGO
Protein Similarities
Method ID Description E-Value
blast CAB00049 Hypothetical protein K04G2.1 [Caenorhabditis elegans] emb|CAA99824.1| Hypothetical protein K04G2.1 [Caenorhabditis elegans] ref|NP_492209.1| K04G2.1 [Caenorhabditis elegans] sp|Q21230|IF2B_CAEEL Putative eukaryotic translation initiation factor 2 beta subunit (eIF-2-beta) 1.0E-112
blast CAE63699 Hypothetical protein CBG08214 [Caenorhabditis briggsae] 5.0E-99
blast NP_080306 eukaryotic translation initiation factor 2, subunit 2 (beta) [Mus musculus] gb|AAH03848.1| Eukaryotic translation initiation factor 2, subunit 2 (beta) [Mus musculus] dbj|BAE26433.1| unnamed protein product [Mus musculus] dbj|BAE26414.1| unnamed protein product [Mus musculus] dbj|BAE39077.1| unnamed protein product [Mus musculus] sp|Q99L45|IF2B_MOUSE Eukaryotic translation initiation factor 2 subunit 2 (Eukaryotic translation initiation factor 2 beta subunit) (eIF-2-beta) 4.0E-56
Protein Domains
Database ID Description E-Value
Pfam IPR002735 EMBL-EBI Translation initiation factor IF5 2.5E-74
Sequence
Target Sequence 
>C. ELEGANS:193644_S_AT
gaaaactccaaagacagccggcgaagaagtagttgaagagaaagttccaactctcgaaat
cggaattggagctcaaaacttgatcgatgcaaaaggggcatggccagattacacatacga
agaagctctcactcttgtctatcaggttatgaaagacaaaaatccagactttgctggaga
caagaagaagttcgccatcaagctcccagaagttgcaagagctggatcaaagaagactgc
tttctccaacttcctcgaaatttgccggcttatgaaaagacaagacaaacacgtgctcca
atttttgctcgcggaattgggaacgactggatccatcgacggaagtaactgtttgattgt
gaaaggaagatggcaacagaaacaatttgaaagtgtcctccggaaatatatcaaggagta
cgtaatgtgccatacttgcaagtcgccagaaacacagctcaccaaggatactcgtctctt
cttcctccaatgtactaactg

BLASTn GenBank NR
Probe Info
Probe Sequence(5'-3') Probe X Probe Y Probe Interrogation
Position 		Strandedness
GAAAACTCCAAAGACAGCCGGCGAA 439 351 162 Antisense
GAAAGTTCCAACTCTCGAAATCGGA 483 357 201 Antisense
GGGCATGGCCAGATTACACATACGA 446 493 257 Antisense
CTCTCACTCTTGTCTATCAGGTTAT 383 231 287 Antisense
ACTTCCTCGAAATTTGCCGGCTTAT 604 99 410 Antisense
AAGACAAACACGTGCTCCAATTTTT 682 147 443 Antisense
GGAACGACTGGATCCATCGACGGAA 61 531 481 Antisense
AATGTGCCATACTTGCAAGTCGCCA 145 163 585 Antisense
GCAAGTCGCCAGAAACACAGCTCAC 395 321 599 Antisense
AACACAGCTCACCAAGGATACTCGT 541 135 612 Antisense
TCTTCTTCCTCCAATGTACTAACTG 17 617 638 Antisense
Sequence Source Affymetrix Proprietary Database